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Company ReportsSmith+Nephew

Smith+Nephew(SNN)

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Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Regranex	Becaplermin	1997-12-16		Diabetic neuropathies , Skin ulcer , Wound healing
Santyl	Collagenase clostridium histolyticum	1965-06-04		—

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Collagenase clostridium histolyticum

,

,

plantar fasciitis

,

,

,

dupuytren contracture

,

penile induration

,

,

,

,

,

male genital diseases

,

psychological sexual dysfunctions

,

genital diseases

Hyaluronate sodium

temporomandibular joint disorders

,

,

rheumatoid arthritis

,

,

,

,

,

ocular hypertension

,

,

open-angle glaucoma

,

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

neoplasm metastasis

,

hematologic neoplasms

,

neurofibromatosis 1

,

neurofibrosarcoma

,

neurofibromatoses

,

nerve sheath neoplasms

,

breast neoplasms

,

,

non-small-cell lung carcinoma

Tribasic calcium phosphate

sickle cell anemia

,

metabolic diseases

,

iron-deficiency anemia

,

,

oxidative stress

,

,

body composition

,

food hypersensitivity

,

protein deficiency

,

,

,

diastolic heart failure

,

macular degeneration

,

,

clostridium infections

,

clostridioides difficile

,

postoperative period

,

feeding and eating disorders

,

health behavior

,

,

endocrine system diseases

,

nutritional and metabolic diseases

,

endocrine bone diseases

,

chronic progressive multiple sclerosis

,

mental processes

,

,

respiratory tract diseases

,

respiration disorders

,

streptococcus agalactiae

,

overactive urinary bladder

,

,

replacement arthroplasty knee

,

substance-related disorders

,

multiple acyl coenzyme a dehydrogenase deficiency

,

essential hypertension

,

,

binge-eating disorder

,

,

,

knee osteoarthritis

,

cardiovascular diseases

,

,

respiratory tract infections

,

,

breast neoplasms

,

digestive signs and symptoms

,

,

,

,

parkinson disease

,

,

,

depressive disorder

,

,

ulcerative colitis

,

,

,

,

bacterial vaginosis

,

alcoholic fatty liver

,

,

autistic disorder

,

autism spectrum disorder

,

,

bone resorption

,

multiple sclerosis

,

,

,

,

major depressive disorder

,

,

,

immunosenescence

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

alcohol drinking

,

,

,

peanut hypersensitivity

,

,

,

,

hyperandrogenism

,

respiratory aspiration of gastric contents

,

,

behavioral symptoms

,

,

pervasive child development disorders

,

,

hepatocellular carcinoma

,

liver neoplasms

,

pneumococcal pneumonia

,

pneumococcal infections

,

,

,

treatment-resistant depressive disorder

,

,

female infertility

,

chemical and drug induced liver injury

,

post-traumatic stress disorders

,

,

,

metabolic syndrome

,

type 2 diabetes mellitus

,

non-alcoholic fatty liver disease

,

gastrointestinal diseases

,

,

communicable diseases

,

,

prediabetic state

,

,

,

,

,

critical illness

,

,

,

glucose intolerance

,

,

,

,

premature birth

,

neonatal sepsis

,

,

,

,

prehypertension

,

postoperative complications

,

urinary tract infections

,

muscle weakness

,

sickle cell anemia

,

,

,

male infertility

,

pediatric obesity

,

,

,

,

,

hypertriglyceridemia

,

colonic neoplasms

,

,

rectal neoplasms

,

,

enteral nutrition

,

gastroenteritis

,

,

,

lactose intolerance

,

migraine disorders

,

prostatic neoplasms

,

female genital neoplasms

,

multiple organ failure

,

cross infection

,

rotavirus infections

,

alzheimer disease

,

mobility limitation

,

physical fitness

,

,

,

urinary bladder neoplasms

,

,

uterine cervical neoplasms

,

ovarian epithelial carcinoma

,

atrial fibrillation

,

systemic scleroderma

,

diffuse scleroderma

,

central serous chorioretinopathy

,

bifidobacterium

,

vaso-occlusive crises

,

,

,

muscle strength

,

,

erectile dysfunction

,

,

,

carpal tunnel syndrome

,

,

healthy volunteers/patients

,

,

,

,

insulin resistance

,

irritable bowel syndrome

,

,

diabetes mellitus

,

,

gastrointestinal microbiome

,

,

iron deficiencies

,

,

,

hypersensitivity

,

,

dietary supplements

,

atopic dermatitis

,

,

anxiety disorders

,

,

kidney diseases

,

,

hypercholesterolemia

,

,

heart disease risk factors

,

polycystic ovary syndrome

,

type 1 diabetes mellitus

,

,

hyperlipidemias

,

human influenza

,

cystic fibrosis

,

chronic kidney failure

,

liver cirrhosis

,

colorectal neoplasms

,

head and neck neoplasms

,

,

congenital hypothyroidism

,

,

attention deficit disorder with hyperactivity

,

digestive system neoplasms

,

,

stomach neoplasms

,

hormone replacement therapy

,

,

,

drug resistant epilepsy

,

,

,

nutritional status

,

,

hyperlipoproteinemias

,

gastrointestinal stromal tumors

,

,

hepatic encephalopathy

,

,

,

,

,

left ventricular dysfunction

,

right ventricular dysfunction

,

ventricular dysfunction

,

,

,

,

cognitive dysfunction

,

,

,

muscular atrophy

,

digestive system diseases

,

chronic renal insufficiency

,

,

,

allergic rhinitis

,

abdominal obesity

,

,

,

chronic obstructive pulmonary disease

,

appetitive behavior

,

intestinal diseases

,

,

sports nutritional physiological phenomena

,

psychological stress

,

metabolic bone diseases

,

sleep initiation and maintenance disorders

,

sleep wake disorders

,

,

glucose metabolism disorders

,

exercise tolerance

,

,

food diet and nutrition

,

,

,

feeding behavior

,

,

satiety response

,

,

inflammatory bowel diseases

,

necrotizing enterocolitis

,

,

male breast neoplasms

,

,

,

,

bariatric surgery

,

,

sensitivity training groups

,

postmenopausal osteoporosis

,

,

body weight changes

,

,

exercise-induced asthma

,

child development

,

congenital heart defects

,

gastric emptying

,

,

,

,

food intolerance

,

resistance training

,

psychological well-being

,

,

psychotic disorders

,

,

vaginal diseases

,

sprains and strains

,

breast milk expression

,

nutrition therapy

,

,

,

,

signs and symptoms

,

growth disorders

,

,

,

atherosclerosis

,

,

hyperlactatemia

,

,

,

,

,

myofascial pain syndromes

,

,

,

obstructive lung diseases

,

,

,

,

,

healthy lifestyle

,

pregnancy complications

,

emotional regulation

,

biological availability

,

,

obstetric labor complications

,

,

coronary artery disease

,

myocardial ischemia

,

,

allergic rhinitis seasonal

,

,

fetal growth retardation

,

,

neurocognitive disorders

,

respiratory signs and symptoms

,

neurodegenerative diseases

,

recovery of function

,

alopecia areata

,

,

post-acute covid-19 syndrome

,

,

extracellular polymeric substance matrix

,

,

,

,

,

learning disabilities

,

neuroprotection

,

preconception care

,

microcirculation

,

pregnancy in obesity

,

laparoscopic cholecystectomy

,

blood glucose self-monitoring

,

,

appetite regulation

,

acid-base imbalance

,

psychological power

,

sweetening agents

,

,

,

,

sedentary behavior

,

,

,

raynaud disease

,

magnetic resonance imaging

,

,

,

decision making

,

hemochromatosis

,

,

,

facioscapulohumeral muscular dystrophy

,

muscular dystrophies

,

myocardial infarction

,

cardiovascular abnormalities

,

acquired immunodeficiency syndrome

,

wounds and injuries

,

wound infection

,

surgical wound infection

,

,

vascular stiffness

,

emotional eating

,

periodontal diseases

,

,

periodontal pocket

,

rheumatoid arthritis

,

,

chronic disease

,

,

severe acute respiratory syndrome

,

blood flow restriction therapy

,

,

,

failure to thrive

,

,

pathologic dilatation

,

,

cardiogenic shock

,

,

vulvovaginal candidiasis

,

gastrointestinal neoplasms

,

coronavirus infections

,

prader-willi syndrome

,

,

echocardiography

,

autonomic nervous system diseases

,

chronobiology disorders

,

,

,

renal insufficiency

,

,

,

anterior cruciate ligament reconstruction

,

,

blood circulation

,

,

,

hyperhomocysteinemia

,

immunologic deficiency syndromes

,

task performance and analysis

,

peripheral arterial disease

,

peripheral vascular diseases

,

,

,

diabetic neuropathies

,

polyneuropathies

,

,

oxygen consumption

,

colonic diseases

,

allergic rhinitis perennial

,

muscle development

,

altitude sickness

,

,

memory disorders

,

lipid metabolism disorders

,

pharmacokinetics

,

ischemic stroke

,

congenital microtia

,

,

,

,

,

waist circumference

,

sjogren's syndrome

,

deglutition disorders

,

,

physical exertion

,

anorexia nervosa

,

,

,

psychogenic polydipsia

,

diabetes insipidus

,

neurogenic diabetes insipidus

,

,

,

,

hip osteoarthritis

,

,

,

microscopic colitis

,

cognition disorders

,

neurodevelopmental disorders

,

diabetic nephropathies

,

hyperinsulinism

,

orthopedic procedures

,

perioperative care

,

carbohydrate loading diet

,

intermittent fasting

,

,

esophageal neoplasms

,

multiple myeloma

,

,

plasma cell neoplasms

,

carbohydrate metabolism

,

,

psychosocial functioning

,

heat exhaustion

,

,

newborn infant diseases

,

systolic heart failure

,

nutrition surveys

,

,

,

,

consciousness disorders

,

,

,

mediterranean diet

,

,

urologic neoplasms

,

,

polysomnography

,

,

,

,

,

chronic hepatitis b

,

,

chronic hepatitis

,

,

addictive behavior

,

,

non-small-cell lung carcinoma

,

,

scheuermann disease

,

spinal osteochondrosis

,

,

,

,

bipolar disorder

,

bipolar and related disorders

,

mycoplasma pneumonia

,

mycoplasma pneumoniae

,

mycoplasma infections

,

pleuropneumonia

,

,

,

,

postpartum depression

,

,

nutrition disorders

,

infant nutrition disorders

,

biliary atresia

,

child nutrition disorders

,

,

,

cardiomyopathies

,

,

systemic inflammatory response syndrome

,

vitamin d deficiency

,

body temperature regulation

,

,

postoperative pain

,

,

patient compliance

,

,

cardiac surgical procedures

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

,

keratoconjunctivitis

,

depressive disorder

,

knee osteoarthritis

,

,

,

myocardial infarction

,

st elevation myocardial infarction

,

,

inferior wall myocardial infarction

,

,

lymph node excision

,

carpal tunnel syndrome

,

open-angle glaucoma

,

,

gingival overgrowth

,

,

dental pulp diseases

,

,

stomach neoplasms

,

striae distensae

,

gingival hyperplasia

,

gingival hypertrophy

,

stomatognathic diseases

,

low-level light therapy

,

non-small-cell lung carcinoma

,

,

,

intra-articular injections

,

,

respiratory tract diseases

,

respiration disorders

,

alcoholic hepatitis

,

thyroid neoplasms

,

,

,

cartilage diseases

,

rotator cuff injuries

,

,

urinary bladder neoplasms

,

diabetic retinopathy

,

congenital abnormalities

,

,

patellofemoral pain syndrome

,

corneal diseases

,

somatoform disorders

,

,

lower urinary tract symptoms

,

,

oxidative stress

,

,

head and neck neoplasms

,

,

,

conjunctival diseases

,

fecal incontinence

,

,

sudden hearing loss

,

multiple myeloma

,

plasma cell neoplasms

,

carcinoma in situ

,

,

non-muscle invasive bladder neoplasms

,

urinary incontinence

,

parkinson disease

,

,

obstructive lung diseases

,

cartilage fractures

,

,

interstitial lung diseases

,

stress urinary incontinence

,

stem cell research

,

noise-induced hearing loss

,

meniere disease

,

large b-cell lymphoma diffuse

,

papillary carcinoma

,

pancreatic neoplasms

,

spinal cord injuries

,

bacterial conjunctivitis

,

male breast neoplasms

,

,

squamous cell carcinoma of head and neck

,

voice disorders

,

laryngeal neoplasms

,

hereditary corneal dystrophies

,

,

arterial occlusive diseases

,

chronic limb-threatening ischemia

,

,

alpha 1-antitrypsin deficiency

,

pulmonary emphysema

,

,

,

,

sprains and strains

,

,

multiple endocrine neoplasia type 1

,

facial paralysis

,

,

pulmonary hypertension

,

hidradenitis suppurativa

,

,

basal cell carcinoma

,

basal cell neoplasms

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

intratympanic injection

,

,

,

type 2 diabetes mellitus

,

periodontal diseases

,

intervertebral disc degeneration

,

interstitial cystitis

,

,

,

capsule opacification

,

trigger finger disorder

,

shoulder impingement syndrome

,

spontaneous abortion

,

,

,

aphthous stomatitis

,

postoperative pain

,

,

,

erectile dysfunction

,

colorectal neoplasms

,

,

,

radiodermatitis

,

gingival hemorrhage

,

bone resorption

,

premature birth

,

,

pancreatic ductal carcinoma

,

,

,

,

cumulative trauma disorders

,

retinal diseases

,

phacoemulsification

,

premature ejaculation

,

,

musculoskeletal diseases

,

,

tendon entrapment

,

,

ductal carcinoma

,

chronic hepatitis c

,

oral submucous fibrosis

,

,

dental calculus

,

critical illness

,

,

,

,

,

olfactory nerve injuries

,

shoulder injuries

,

retinopathy of prematurity

,

,

prostatic diseases

,

failed back surgery syndrome

,

,

knee osteoarthritis

,

dry eye syndromes

,

keratoconjunctivitis sicca

,

,

,

,

,

wounds and injuries

,

,

tissue adhesions

,

,

,

,

,

,

healthy volunteers/patients

,

temporomandibular joint disorders

,

,

,

,

gingival recession

,

hip osteoarthritis

,

,

,

atrophic vaginitis

,

,

,

temporomandibular joint dysfunction syndrome

,

,

diabetes mellitus

,

periodontal pocket

,

urinary tract infections

,

breast neoplasms

,

,

,

meibomian gland dysfunction

,

,

,

,

,

prostatic neoplasms

,

chronic periodontitis

,

,

sjogren's syndrome

,

,

,

,

alveolar bone loss

,

,

keratoconjunctivitis

,

,

,

dental implants

,

,

,

,

,

postoperative complications

,

,

patient satisfaction

,

,

elbow tendinopathy

,

vesico-ureteral reflux

,

,

,

communicable diseases

,

,

anterior cruciate ligament injuries

,

peri-implantitis

,

,

,

,

allergic conjunctivitis

,

,

chronic obstructive pulmonary disease

,

,

,

,

thyroid diseases

,

,

photorefractive keratectomy

,

male infertility

,

,

,

,

beta-thalassemia

,

,

,

injection site reaction

,

,

,

,

induced abortion

,

actinic keratosis

,

,

,

graves ophthalmopathy

,

,

cesarean section

,

obstetric delivery

,

,

uterine cervical neoplasms

,

alveolar ridge augmentation

,

physiological sexual dysfunction

,

,

sensorineural hearing loss

,

polycystic ovary syndrome

,

,

,

,

procedural pain

,

linear energy transfer

,

,

,

,

depressive disorder

,

re-epithelialization

,

cosmetic techniques

,

uterine diseases

,

retained placenta

,

,

,

intraocular pressure

,

physiological stress

,

breast implantation

,

ethmoid sinusitis

,

,

,

surgical blood loss

,

,

bacterial vaginosis

,

surgical wound dehiscence

,

,

rheumatoid arthritis

,

gastrointestinal diseases

,

intestinal diseases

,

,

,

gastroesophageal reflux

,

,

vaginal diseases

,

peptic esophagitis

,

,

vocal cord paralysis

,

,

,

oral lichen planus

,

retinal detachment

,

,

rectal neoplasms

,

,

intratracheal intubation

,

,

,

,

venous insufficiency

,

cataract extraction

,

,

,

coronary artery disease

,

spinal stenosis

,

papillomavirus infections

,

,

,

fuchs' endothelial dystrophy

,

furcation defects

,

skin manifestations

,

,

,

femoracetabular impingement

,

intervertebral disc displacement

,

refractive errors

,

,

,

hypertrophic cicatrix

,

dissociative disorders

,

,

phototoxic dermatitis

,

contact dermatitis

,

photoallergic dermatitis

,

,

neuroendocrine tumors

,

penile prosthesis

,

,

,

,

,

endometrial neoplasms

,

retinal vein occlusion

,

,

penile induration

,

endoscopic mucosal resection

,

atopic dermatitis

,

,

myofascial pain syndromes

,

,

,

periodontal attachment loss

,

,

,

,

,

,

patient reported outcome measures

,

disease progression

,

peripheral arterial disease

,

peripheral vascular diseases

,

iron-deficiency anemia

,

iron deficiencies

,

,

viral pneumonia

,

,

coronary disease

,

chondromalacia patellae

,

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

,

intradermal injections

,

,

hemorrhagic cystitis

,

squamous intraepithelial lesions of the cervix

,

,

male urogenital diseases

,

urogenital diseases

,

,

personal satisfaction

,

,

executive function

,

physical fitness

,

habitual abortion

,

,

,

topical administration

,

endophthalmitis

,

gynecologic surgical procedures

,

precancerous conditions

,

alcoholic liver diseases

,

,

metabolic diseases

,

metabolic syndrome

,

,

high-risk pregnancy

,

stress fractures

,

randomized controlled trials as topic

,

spinal diseases

,

,

,

,

gender dysphoria

,

cerebral infarction

,

,

magnetic resonance angiography

,

,

neurodegenerative diseases

,

,

refractive surgical procedures

,

surgical amputation

,

,

,

,

,

sleep apnea syndromes

,

,

hypersensitivity

,

nociceptive pain

,

,

acute kidney injury

,

,

gastrointestinal microbiome

,

,

fertilization in vitro

,

deglutition disorders

,

,

,

tooth extraction

,

,

,

pleural diseases

,

respiratory system abnormalities

,

cystic fibrosis

,

tibial meniscus injuries

,

open abdomen techniques

,

angle-closure glaucoma

,

embryo implantation

,

corneal transplantation

,

,

,

,

,

central nervous system neoplasms

,

kidney neoplasms

,

,

nervous system neoplasms

,

,

body dysmorphic disorders

,

,

premature aging

,

drug-related side effects and adverse reactions

,

choroid diseases

,

,

dental pulp necrosis

,

,

,

multiple abnormalities

,

pityriasis rubra pilaris

,

,

,

,

,

uterine hemorrhage

,

,

dental pulp exposure

,

metabolic bone diseases

,

afibrinogenemia

,

transitional cell carcinoma

,

corneal opacity

,

nasal obstruction

,

,

muscle spasticity

,

non-alcoholic fatty liver disease

,

,

,

tendon injuries

,

,

prostatic hyperplasia

,

,

,

,

muscle rigidity

,

esophageal neoplasms

,

,

,

sinus floor augmentation

,

,

,

,

,

,

maxillofacial injuries

,

teratozoospermia

,

ventilator-associated pneumonia

,

cross infection

,

healthcare-associated pneumonia

,

,

,

,

,

,

,

suppurative otitis media

,

,

,

dietary supplements

,

,

,

otorhinolaryngologic diseases

,

,

pediatric obesity

,

rheumatic diseases

,

rheumatic fever

,

collagen diseases

,

alphapapillomavirus

,

uterine cervical dysplasia

,

subarachnoid hemorrhage

,

acute lung injury

,

plantar fasciitis

,

,

retinal perforations

,

,

radiofrequency ablation

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

,

pathologic constriction

,

dentin sensitivity

,

tooth discoloration

,

dental implantation

,

,

hyperpigmentation

,

,

,

,

,

plastic surgery procedures

,

,

general anesthesia

,

vascular malformations

,

,

peripheral nervous system diseases

,

tissue transplantation

,

,

acupuncture therapy

cartilage diseases

bowen's disease

,

,

healthy volunteers/patients

,

,

actinic keratosis

,

,

,

basal cell neoplasms

,

,

herpes labialis

,

hypertrophic cicatrix

,

,

wound infection

,

,

surgical wound infection

,

,

breast neoplasms

,

,

pulmonary hypertension

,

pulmonary arterial hypertension

,

cutaneous leishmaniasis

,

,

,

vascular diseases

,

peripheral arterial disease

,

peripheral vascular diseases

,

,

obstetric labor complications

,

surgical wound dehiscence

,

,

,

,

communicable diseases

,

,

wounds and injuries

,

catheter-related infections

,

postoperative pain

,

,

,

,

,

,

catheterization

,

basal cell carcinoma

,

postoperative cognitive complications

,

,

emergence delirium

,

cognitive dysfunction

,

,

local anesthesia

,

,

,

tobacco use disorder

,

connective tissue diseases

,

,

,

,

,

,

coronary artery disease

,

,

,

,

central venous catheters

,

,

,

cardiovascular diseases

,

atherosclerosis

,

,

arterial occlusive diseases

,

,

,

peripheral catheterization

,

,

aortic dissection

,

hip osteoarthritis

,

replacement arthroplasty hip

,

conduction anesthesia

,

brachial plexus block

,

replacement arthroplasty knee

,

spinal anesthesia

,

cesarean section

,

,

eosinophilic esophagitis

,

,

squamous cell carcinoma

,

squamous cell neoplasms

,

postoperative complications

,

,

postoperative nausea and vomiting

,

,

,

,

,

pulmonary ventilation

,

,

traumatic brain injuries

,

,

myasthenia gravis

,

,

,

,

obstetrical analgesia

,

angina pectoris

,

,

,

pituitary neoplasms

,

plastic surgery procedures

,

,

ultrasonography

,

blood specimen collection

,

,

respiratory distress syndrome

,

respiratory insufficiency

,

traumatic amputation

,

premature birth

,

,

diabetes mellitus

,

spinal cord injuries

,

rheumatic diseases

,

vascular access devices

,

,

randomized controlled trials as topic

,

newborn infant diseases

,

occlusive dressings

,

prosthesis-related infections

,

tissue adhesions

,

chronic kidney failure

,

kidney diseases

,

,

venous thrombosis

,

head and neck neoplasms

,

pain management

,

,

1

2

>

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