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Disease Reports

Company ReportsSmith+Nephew

Smith+Nephew(SNN)

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Clinical Trials

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Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Regranex	Becaplermin	1997-12-16		Diabetic neuropathies , Skin ulcer , Wound healing
Santyl	Collagenase clostridium histolyticum	1965-06-04		—

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Collagenase clostridium histolyticum

dupuytren contracture

,

Hyaluronate sodium

healthy volunteers/patients

,

pediatric obesity

,

pneumococcal infections

,

Tribasic calcium phosphate

periodontal pocket

,

bone regeneration

,

,

,

dental restoration failure

,

,

fracture healing

,

spinal cord neoplasms

,

spinal cord compression

,

,

,

bone resorption

,

tooth demineralization

,

alveolar bone grafting

,

spinal diseases

,

,

spondylolisthesis

,

edentulous jaw partially

,

,

spinal stenosis

,

alveolar ridge augmentation

,

humeral fractures

,

root canal therapy

,

,

,

,

sickle cell anemia

,

,

foot deformities

,

congenital foot deformities

,

,

chronic periodontitis

,

femoral neck fractures

,

tibial fractures

,

peri-implantitis

,

,

,

,

,

edentulous mouth

,

orbital implants

,

,

mandibular fractures

,

,

craniocerebral trauma

,

carpal tunnel syndrome

,

,

,

,

dentin sensitivity

,

hypersensitivity

,

alveolar bone loss

,

periodontal diseases

,

calcium metabolism disorders

,

intervertebral disc degeneration

,

hip osteoarthritis

,

replacement arthroplasty hip

,

,

,

tooth extraction

,

,

femoral fractures

,

metabolic bone diseases

,

furcation defects

,

stress urinary incontinence

,

osteoporotic fractures

,

intervertebral disc displacement

,

periodontal attachment loss

,

,

,

ossification of posterior longitudinal ligament

,

craniosynostoses

,

dental caries susceptibility

,

,

,

sinus floor augmentation

,

dental implants

,

congenital abnormalities

,

gingival recession

,

,

rheumatoid arthritis

,

healthy volunteers/patients

,

,

,

tissue preservation

,

,

,

,

cartilage diseases

,

dentofacial deformities

,

,

,

mandibular prosthesis

,

dental enamel hypoplasia

,

molar hypomineralization

,

,

,

,

,

,

diabetes mellitus

,

knee osteoarthritis

,

,

tooth discoloration

,

urinary incontinence

,

,

,

conductive hearing loss

,

,

mixed conductive-sensorineural hearing loss

,

jaw abnormalities

,

tooth bleaching

,

spinal fractures

,

chondrocalcinosis

,

,

neoplasm metastasis

,

,

,

,

,

,

,

,

forearm injuries

,

thoracic injuries

,

communicable diseases

,

replacement arthroplasty knee

,

coronary artery bypass

,

maxillary sinusitis

,

paranasal sinus diseases

,

,

deglutition disorders

,

,

,

pathologic constriction

,

,

,

maxillofacial abnormalities

,

,

,

spinal cord diseases

,

,

spinal dysraphism

,

tooth abnormalities

,

,

ununited fractures

,

,

coronary artery disease

,

hemiarthroplasty

,

,

,

,

,

,

gene expression

,

,

hypercholesterolemia

,

congenital hip dislocation

,

femur head necrosis

,

developmental dysplasia of the hip

,

hip dislocation

,

breast neoplasms

,

,

gustatory sweating

,

patient acceptance of health care

,

,

allergic rhinitis

,

,

bone malalignment

,

gastroesophageal reflux

,

,

dental pulp diseases

,

,

dental occlusion

,

,

bone transplantation

,

type 2 diabetes mellitus

,

,

dental enamel hypomineralization

,

iron-deficiency anemia

,

metabolic diseases

,

oxidative stress

,

,

,

body composition

,

food hypersensitivity

,

protein deficiency

,

,

,

coronary artery disease

,

myocardial ischemia

,

,

neuroendocrine tumors

,

colonic neoplasms

,

coronary disease

,

diastolic heart failure

,

macular degeneration

,

overactive urinary bladder

,

,

clostridium infections

,

clostridioides difficile

,

postoperative period

,

feeding and eating disorders

,

health behavior

,

,

endocrine system diseases

,

nutritional and metabolic diseases

,

endocrine bone diseases

,

chronic progressive multiple sclerosis

,

mental processes

,

,

,

respiratory tract diseases

,

respiration disorders

,

streptococcus agalactiae

,

,

replacement arthroplasty knee

,

substance-related disorders

,

multiple acyl coenzyme a dehydrogenase deficiency

,

essential hypertension

,

,

binge-eating disorder

,

,

,

,

cardiovascular diseases

,

respiratory tract infections

,

thyroid neoplasms

,

thyroid diseases

,

,

breast neoplasms

,

digestive signs and symptoms

,

,

,

,

parkinson disease

,

metabolic bone diseases

,

,

papillary thyroid cancer

,

,

ulcerative colitis

,

,

,

,

,

brain concussion

,

neuroendocrine carcinoma

,

,

,

bacterial vaginosis

,

alcohol drinking

,

alcoholic fatty liver

,

autistic disorder

,

autism spectrum disorder

,

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

,

,

traumatic brain injuries

,

,

post-concussion syndrome

,

bone resorption

,

multiple sclerosis

,

,

,

angina pectoris

,

,

cluster headache

,

,

major depressive disorder

,

,

immunosenescence

,

,

temporomandibular joint disorders

,

temporomandibular joint dysfunction syndrome

,

,

,

peanut hypersensitivity

,

follicular adenocarcinoma

,

,

brain stem neoplasms

,

medullary carcinoma

,

,

,

,

hyperandrogenism

,

respiratory aspiration of gastric contents

,

,

behavioral symptoms

,

,

pervasive child development disorders

,

paroxysmal hemicrania

,

,

trigeminal neuralgia

,

,

giant cell granuloma

,

,

hepatocellular carcinoma

,

liver neoplasms

,

hepatic insufficiency

,

pneumococcal pneumonia

,

pneumococcal infections

,

,

,

,

headache disorders

,

primary headache disorders

,

trigeminal autonomic cephalalgias

,

trigeminal nerve diseases

,

female infertility

,

,

neurofibromatoses

,

,

chemical and drug induced liver injury

,

post-traumatic stress disorders

,

,

,

metabolic syndrome

,

type 2 diabetes mellitus

,

,

communicable diseases

,

non-alcoholic fatty liver disease

,

,

gastrointestinal diseases

,

,

knee osteoarthritis

,

,

prediabetic state

,

,

,

postmenopausal osteoporosis

,

,

,

critical illness

,

,

glucose intolerance

,

,

,

,

,

premature birth

,

neonatal sepsis

,

,

urinary tract infections

,

muscle weakness

,

sickle cell anemia

,

,

,

male infertility

,

,

pediatric obesity

,

,

,

,

,

hypertriglyceridemia

,

prehypertension

,

postoperative complications

,

,

,

enteral nutrition

,

gastroenteritis

,

,

,

lactose intolerance

,

prostatic neoplasms

,

multiple organ failure

,

atrial fibrillation

,

cross infection

,

rotavirus infections

,

alzheimer disease

,

mobility limitation

,

physical fitness

,

,

,

ovarian neoplasms

,

urinary bladder neoplasms

,

female genital neoplasms

,

uterine cervical neoplasms

,

systemic scleroderma

,

diffuse scleroderma

,

central serous chorioretinopathy

,

bifidobacterium

,

,

,

muscle strength

,

,

erectile dysfunction

,

,

,

carpal tunnel syndrome

,

migraine disorders

,

healthy volunteers/patients

,

,

,

,

,

,

insulin resistance

,

irritable bowel syndrome

,

,

diabetes mellitus

,

,

,

gastrointestinal microbiome

,

,

,

hypersensitivity

,

iron deficiencies

,

dietary supplements

,

,

atopic dermatitis

,

,

,

kidney diseases

,

,

hypercholesterolemia

,

,

anxiety disorders

,

depressive disorder

,

,

heart disease risk factors

,

polycystic ovary syndrome

,

type 1 diabetes mellitus

,

,

post-traumatic headache

,

chronic kidney failure

,

hyperlipidemias

,

human influenza

,

liver cirrhosis

,

myofascial pain syndromes

,

,

cystic fibrosis

,

head and neck neoplasms

,

colorectal neoplasms

,

,

,

,

hyperparathyroidism

,

,

,

congenital hypothyroidism

,

,

attention deficit disorder with hyperactivity

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

,

,

stomach neoplasms

,

,

forearm injuries

,

primary hyperparathyroidism

,

,

,

premenstrual syndrome

,

hormone replacement therapy

,

secondary headache disorders

,

prescription drug overuse

,

,

,

,

drug resistant epilepsy

,

,

,

nutritional status

,

,

hyperlipoproteinemias

,

gastrointestinal stromal tumors

,

hepatic encephalopathy

,

,

,

,

,

left ventricular dysfunction

,

right ventricular dysfunction

,

ventricular dysfunction

,

,

,

,

,

cognitive dysfunction

,

,

chronic renal insufficiency

,

digestive system diseases

,

muscular atrophy

,

chronic obstructive pulmonary disease

,

allergic rhinitis

,

,

abdominal obesity

,

migraine with aura

,

,

,

obstructive lung diseases

,

appetitive behavior

,

intestinal diseases

,

sports nutritional physiological phenomena

,

sleep wake disorders

,

,

glucose metabolism disorders

,

exercise tolerance

,

,

food diet and nutrition

,

,

body weight changes

,

migraine without aura

,

psychological stress

,

,

feeding behavior

,

,

satiety response

,

,

,

congenital heart defects

,

necrotizing enterocolitis

,

,

male breast neoplasms

,

,

,

,

post-acute covid-19 syndrome

,

bariatric surgery

,

sensitivity training groups

,

,

,

exercise-induced asthma

,

child development

,

inflammatory bowel diseases

,

gastric emptying

,

,

,

,

food intolerance

,

resistance training

,

,

psychotic disorders

,

,

vaginal diseases

,

sprains and strains

,

breast milk expression

,

nutrition therapy

,

,

,

,

signs and symptoms

,

diabetes insipidus

,

growth disorders

,

,

,

atherosclerosis

,

,

hyperlactatemia

,

,

,

,

wounds and injuries

,

,

,

hypophosphatemia

,

,

,

,

,

,

rectal neoplasms

,

healthy lifestyle

,

,

pregnancy complications

,

sleep initiation and maintenance disorders

,

emotional regulation

,

biological availability

,

,

obstetric labor complications

,

,

,

allergic rhinitis seasonal

,

,

fetal growth retardation

,

,

,

respiratory signs and symptoms

,

neurodegenerative diseases

,

recovery of function

,

alopecia areata

,

,

,

endocrine gland neoplasms

,

islet cell adenoma

,

multiple endocrine neoplasia

,

extracellular polymeric substance matrix

,

,

,

,

nephrogenic diabetes insipidus

,

neuroprotection

,

,

preconception care

,

microcirculation

,

pregnancy in obesity

,

laparoscopic cholecystectomy

,

blood glucose self-monitoring

,

,

appetite regulation

,

acid-base imbalance

,

psychological power

,

sweetening agents

,

ulnar neuropathies

,

,

,

,

sedentary behavior

,

,

,

raynaud disease

,

magnetic resonance imaging

,

,

,

decision making

,

hemochromatosis

,

,

mental disorders

,

problem behavior

,

,

facioscapulohumeral muscular dystrophy

,

muscular dystrophies

,

myocardial infarction

,

cardiovascular abnormalities

,

acquired immunodeficiency syndrome

,

wound infection

,

surgical wound infection

,

bacterial infections

,

,

,

nervous system diseases

,

chronic periodontitis

,

infectious arthritis

,

familial hypophosphatemic rickets

,

hypophosphatemic rickets

,

,

,

vascular stiffness

,

periodontal diseases

,

periodontal pocket

,

rheumatoid arthritis

,

chronic disease

,

,

severe acute respiratory syndrome

,

blood flow restriction therapy

,

,

failure to thrive

,

,

pathologic dilatation

,

,

cardiogenic shock

,

,

vulvovaginal candidiasis

,

coronavirus infections

,

prader-willi syndrome

,

,

echocardiography

,

autonomic nervous system diseases

,

chronobiology disorders

,

,

,

renal insufficiency

,

,

,

anterior cruciate ligament reconstruction

,

,

blood circulation

,

,

hyperhomocysteinemia

,

immunologic deficiency syndromes

,

task performance and analysis

,

peripheral arterial disease

,

peripheral vascular diseases

,

,

diabetic neuropathies

,

polyneuropathies

,

,

oxygen consumption

,

colonic diseases

,

allergic rhinitis perennial

,

muscle development

,

,

memory disorders

,

lipid metabolism disorders

,

pharmacokinetics

,

ischemic stroke

,

congenital microtia

,

,

,

,

spinal cord injuries

,

,

,

,

,

,

osteoporotic fractures

,

medication adherence

,

waist circumference

,

sjogren's syndrome

,

deglutition disorders

,

,

physical exertion

,

anorexia nervosa

,

,

,

psychogenic polydipsia

,

neurogenic diabetes insipidus

,

,

,

,

hip osteoarthritis

,

microscopic colitis

,

cognition disorders

,

neurocognitive disorders

,

psychological well-being

,

neurodevelopmental disorders

,

diabetic nephropathies

,

hyperinsulinism

,

orthopedic procedures

,

perioperative care

,

carbohydrate loading diet

,

intermittent fasting

,

,

esophageal neoplasms

,

multiple myeloma

,

,

plasma cell neoplasms

,

carbohydrate metabolism

,

,

psychosocial functioning

,

heat exhaustion

,

,

newborn infant diseases

,

systolic heart failure

,

nutrition surveys

,

,

,

consciousness disorders

,

,

,

,

mediterranean diet

,

,

urologic neoplasms

,

,

polysomnography

,

interstitial cystitis

,

,

,

,

,

chronic hepatitis b

,

,

chronic hepatitis

,

,

,

addictive behavior

,

,

non-small-cell lung carcinoma

,

,

scheuermann disease

,

spinal osteochondrosis

,

,

,

,

,

,

bipolar disorder

,

bipolar and related disorders

,

mycoplasma pneumonia

,

mycoplasma pneumoniae

,

mycoplasma infections

,

pleuropneumonia

,

,

,

,

postpartum depression

,

,

,

nutrition disorders

,

infant nutrition disorders

,

biliary atresia

,

child nutrition disorders

,

,

,

cardiomyopathies

,

,

systemic inflammatory response syndrome

,

vitamin d deficiency

,

body temperature regulation

healthy volunteers/patients

,

wounds and injuries

,

wound infection

,

surgical wound infection

,

,

communicable diseases

,

cesarean section

,

,

surgical wound dehiscence

,

,

,

,

,

venous insufficiency

Decellularized dermal allograft

chronic kidney failure

,

kidney diseases

,

renal insufficiency

tooth extraction

,

alveolar bone loss

,

alveolar ridge augmentation

healthy volunteers/patients

,

,

,

,

venous insufficiency

vaginal diseases

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