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Smith+Nephew
Smith+Nephew
(SNN)
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Clinical Trials
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Therapeutic Areas:
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Classification:
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Include Generics:
Trade Name
Drug Name
Approved
Patent Expires
Indication
Regranex
Becaplermin
1997-12-16
Diabetic neuropathies
,
Skin ulcer
,
Wound healing
Santyl
Collagenase
1965-06-04
Burns
,
Skin ulcer
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Collagenase clostridium histolyticum
bursitis
,
cutis laxa
,
edema
,
dupuytren contracture
,
penile induration
,
cellulite
,
contracture
,
recurrence
,
male genital diseases
,
psychological sexual dysfunctions
,
genital diseases
Collagenase
ulcer
,
pressure ulcer
,
diabetic foot
,
foot ulcer
Hyaluronate sodium
temporomandibular joint disorders
,
temporomandibular joint dysfunction syndrome
,
osteoarthritis
Fibrinogen
ischemia
,
diabetic foot
,
arterial occlusive diseases
Sodium chloride
urinary bladder neoplasms
,
non-muscle invasive bladder neoplasms
Petrolatum, white
atopic dermatitis
,
eczema
,
dermatitis
,
staphylococcal infections
Foster
pediatric obesity
,
pneumococcal infections
,
herpes zoster
Hydroxyapatite
rheumatoid arthritis
,
arthritis
,
osteoarthritis
Maltodextrin
diarrhea
Monovisc
knee osteoarthritis
,
osteoarthritis
Alginate
wounds and injuries
,
wound infection
,
surgical wound infection
,
infections
,
communicable diseases
,
cesarean section
,
surgical wound
,
surgical wound dehiscence
,
rupture
,
varicose ulcer
,
ulcer
,
leg ulcer
,
venous insufficiency
Allograft
diabetes mellitus
,
type 1 diabetes mellitus
,
hypoglycemia
,
diabetic nephropathies
,
hypertension
,
glomerulonephritis
,
iga glomerulonephritis
,
renal hypertension
,
lung transplantation
,
leukemia
,
myelodysplastic syndromes
,
bcr-abl positive chronic myelogenous leukemia
,
myeloid leukemia
,
preleukemia
,
syndrome
,
cytomegalovirus infections
,
kidney transplantation
,
chronic kidney failure
,
renal insufficiency
,
immunosuppression therapy
,
heart transplantation
,
kidney diseases
,
fibrosis
,
interstitial lung diseases
,
transplantation
,
graft rejection
Collastat
acne vulgaris
,
hypertrophy
,
rupture
,
anterior cruciate ligament injuries
,
peripheral nerve injuries
,
aging
,
neoplasms
,
type 2 diabetes mellitus
,
hereditary corneal dystrophies
,
myocardial infarction
,
pathologic constriction
,
hypertrophic cicatrix
,
depression
,
crohn disease
,
inflammatory bowel diseases
,
intestinal diseases
,
hydrophthalmos
,
renal cell carcinoma
,
urethral stricture
,
brain injuries
,
skin neoplasms
,
melanoma
,
radius fractures
,
wrist fractures
,
corneal injuries
,
temporomandibular joint disorders
,
temporomandibular joint dysfunction syndrome
,
ulcerative colitis
,
left ventricular dysfunction
,
ventricular dysfunction
,
stem cell transplantation
,
vocal cord dysfunction
,
urinary retention
,
foot injuries
,
lymphoma
,
juvenile arthritis
,
hematologic diseases
,
uterine cervical incompetence
,
dental pulp exposure
,
junctional epidermolysis bullosa
,
cicatrix
,
fibrosis
,
rheumatoid arthritis
,
spinal cord injuries
,
pulmonary fibrosis
,
lymphedema
,
systemic scleroderma
,
diffuse scleroderma
,
liver cirrhosis
,
bone fractures
,
female infertility
,
cardiomyopathies
,
disease
,
edentulous jaw
,
urinary incontinence
,
erectile dysfunction
,
retinal detachment
,
recurrence
,
premature birth
,
type 1 diabetes mellitus
,
muscular diseases
,
myopia
,
hyperopia
,
connective tissue diseases
,
enuresis
,
edentulous jaw partially
,
aggressive periodontitis
,
knee injuries
,
pigmentation
,
pathologic processes
,
localized scleroderma
,
herniorrhaphy
,
metabolic diseases
,
liver neoplasms
,
muscular dystrophies
,
sclerosis
,
pseudarthrosis
,
body weight
,
nasal septal perforation
,
dry socket
,
osteitis
,
osteochondrodysplasias
,
stress urinary incontinence
,
aggression
,
phototoxic dermatitis
,
ketosis
,
sleep
,
idiopathic pulmonary fibrosis
,
malnutrition
,
hyperpigmentation
,
primary ovarian insufficiency
,
premature menopause
,
islets of langerhans transplantation
,
non-alcoholic fatty liver disease
,
fatty liver
,
alcoholic fatty liver
,
leiomyoma
,
myofibroma
,
keratosis
,
astigmatism
,
surgical anastomosis
,
root canal therapy
,
cytokine release syndrome
,
hereditary eye diseases
,
sensorineural hearing loss
,
craniofacial abnormalities
,
congenital microtia
,
hepatectomy
,
breast cancer lymphedema
,
chronic disease
,
cystectomy
,
lung diseases
,
interstitial lung diseases
,
cell- and tissue-based therapy
,
glycogen storage disease type ii
,
lysosomal storage diseases
,
glycogen storage disease
,
ununited fractures
,
growth disorders
,
child nutrition disorders
,
child development
,
carcinoma
,
squamous cell carcinoma
,
squamous cell neoplasms
,
pathologic dilatation
,
intervertebral disc degeneration
,
hernia
,
epidermolysis bullosa
,
epidermolysis bullosa dystrophica
,
communicable diseases
,
keratitis
,
corneal ulcer
,
burns
,
facies
,
wound infection
,
surgical wound infection
,
cleft lip
,
renal insufficiency
,
pterygium
,
alopecia
,
dental pulp necrosis
,
necrosis
,
rectal fistula
,
osteochondritis
,
cartilage fractures
,
inguinal hernia
,
chronic kidney failure
,
kidney diseases
,
congenital abnormalities
,
cataract
,
neoplasm metastasis
,
abdominoplasty
,
overweight
,
rectal neoplasms
,
obesity
,
periapical periodontitis
,
covid-19
,
osteochondritis dissecans
,
ventral hernia
,
arteriovenous fistula
,
weight loss
,
mammaplasty
,
breast implantation
,
uveitis
,
incisional hernia
,
chronic renal insufficiency
,
tendon entrapment
,
arterial occlusive diseases
,
intermittent claudication
,
chronic hepatitis c
,
hepatitis
,
hepatitis a
,
neovascular glaucoma
,
angle-closure glaucoma
,
trabeculectomy
,
endometrial neoplasms
,
uterine cervical neoplasms
,
cardiac surgical procedures
,
hypercholesterolemia
,
brain neoplasms
,
apexification
,
replacement arthroplasty
,
vascular system injuries
,
skin transplantation
,
angina pectoris
,
stable angina
,
pelvic neoplasms
,
bone malalignment
,
keratoconus
,
gingival recession
,
diabetic foot
,
wounds and injuries
,
ulcer
,
foot ulcer
,
osteoarthritis
,
dental implants
,
knee osteoarthritis
,
alveolar bone loss
,
atrophy
,
glaucoma
,
periodontitis
,
peri-implantitis
,
alveolar ridge augmentation
,
corneal diseases
,
wound healing
,
tooth extraction
,
infections
,
tooth loss
,
bone resorption
,
skin diseases
,
postoperative pain
,
syndrome
,
periodontal diseases
,
rotator cuff injuries
,
fistula
,
varicose ulcer
,
surgical wound
,
breast neoplasms
,
heart failure
,
osteoporosis
,
tendinopathy
,
skin aging
,
cutis laxa
,
furcation defects
,
hemorrhage
,
arthritis
,
edentulous mouth
,
hypertension
,
inflammation
,
infertility
,
leg ulcer
,
open-angle glaucoma
,
stress fractures
,
tissue adhesions
,
diabetes mellitus
,
chronic periodontitis
,
cardiovascular diseases
,
dry eye syndromes
,
eye diseases
,
cartilage diseases
,
arthralgia
,
coronary artery disease
,
dental implantation
,
pancreatic fistula
,
stroke
,
ischemia
,
bone diseases
,
anodontia
,
pain
,
hemostasis
,
edema
,
malocclusion
,
thrombosis
,
acute coronary syndrome
,
vascular diseases
,
infarction
,
keratoconjunctivitis sicca
,
postmenopausal osteoporosis
,
pulmonary arterial hypertension
,
peripheral arterial disease
,
peripheral vascular diseases
,
postoperative complications
,
plantar fasciitis
,
fasciitis
,
seroma
,
gingival diseases
,
hereditary nephritis
,
cerebral infarction
,
atherosclerosis
,
glioblastoma
,
tenosynovitis
,
pancreatic neoplasms
,
multiple myeloma
,
plasma cell neoplasms
,
familial primary pulmonary hypertension
,
pulmonary hypertension
,
penile induration
,
keloid
,
contracture
,
sinus floor augmentation
,
mucositis
,
angle class i malocclusion
,
diastolic heart failure
,
glomerulonephritis
,
iga glomerulonephritis
,
tibial fractures
,
morphine dependence
,
endometrial hyperplasia
,
dupuytren contracture
,
bandages
,
drainage
,
craniosynostoses
,
stomatitis
,
stem cell research
,
ichthyosis
,
digestive signs and symptoms
,
death
,
albuminuria
,
diabetes complications
,
urinary tract infections
,
dental prosthesis
,
healthy volunteers/patients
,
tissue preservation
,
bone regeneration
,
spinal diseases
,
pressure ulcer
,
ehlers-danlos syndrome
,
dental caries
,
metabolic bone diseases
,
hypersensitivity
,
heart diseases
,
exercise
,
sarcopenia
,
prolapse
,
osteogenesis imperfecta
,
regeneration
,
dermatitis
,
tennis elbow
,
tooth diseases
,
alveolar bone grafting
,
impacted tooth
,
skin manifestations
,
bone density
,
myocardial ischemia
,
food diet and nutrition
,
alopecia areata
,
hypotrichosis
,
gastroesophageal reflux
,
dietary supplements
,
periodontal pocket
,
congenital heart defects
,
vitiligo
,
ingrown nails
,
pelvic organ prolapse
,
heterologous transplantation
,
erythema
,
soft tissue infections
,
stomatognathic diseases
,
striae distensae
,
aortic valve stenosis
,
osteochondrosis
,
injection site reaction
,
dwarfism
,
maxillary sinusitis
,
coronary disease
,
chronic pain
,
tooth fractures
,
traumatic brain injuries
,
hip osteoarthritis
,
rheumatic diseases
,
collagen diseases
,
prediabetic state
,
aortic dissection
,
purpura
,
intervertebral disc displacement
,
cerebrospinal fluid leak
,
sciatica
,
allergic contact dermatitis
,
metabolic syndrome
,
urogenital diseases
,
gingivitis
,
meniscectomy
,
atrophic vaginitis
,
adenocarcinoma
,
tooth avulsion
,
hemophilia b
,
mandibular prosthesis
,
liver diseases
,
uterine cervical diseases
,
thyroid neoplasms
,
thyroid diseases
,
guided tissue regeneration
,
surgical wound dehiscence
,
muscle strength
,
hiatal hernia
,
biological availability
,
surgical blood loss
,
head and neck neoplasms
,
periodontal attachment loss
,
neck pain
,
body composition
,
low back pain
,
spondylosis
,
osteonecrosis
,
colorectal neoplasms
,
marfan syndrome
,
arachnodactyly
,
radiodermatitis
,
tibial meniscus injuries
,
salivation
,
environmental biomarkers
,
somatoform disorders
,
food
,
diet
,
thrombocytopenic purpura idiopathic
,
thrombocytopenic purpura
,
surgical amputation
,
von willebrand diseases
,
calcium metabolism disorders
,
osteoporotic fractures
,
extracellular polymeric substance matrix
,
cardiotoxicity
,
therapeutics
,
spinal fusion
,
neurofibromatosis 1
,
neurofibromatoses
,
neurofibroma
,
pregnancy
,
appetitive behavior
,
facial paralysis
,
facial nerve diseases
,
bell palsy
,
paralysis
,
varicose veins
,
esthetics
,
male urogenital diseases
,
mood disorders
,
mental disorders
,
problem behavior
,
corneal opacity
,
cardiovascular abnormalities
,
lichen sclerosus et atrophicus
,
joint diseases
,
congenital hand deformities
,
colonic neoplasms
,
blister
,
nerve compression syndromes
,
charcot-marie-tooth disease
,
hereditary sensory and motor neuropathy
,
alcoholic liver diseases
,
tympanic membrane perforation
,
biliary fistula
,
laparoscopy
,
lymph node excision
,
bacterial drug resistance
,
pierre robin syndrome
,
voice disorders
,
thyroid nodule
,
disease progression
,
heart valve diseases
,
tetralogy of fallot
,
peritonitis
,
shoulder injuries
,
refractive errors
,
prosthesis failure
,
patient satisfaction
,
mesial movement of teeth
,
infectious arthritis
,
platelet activation
,
skin abnormalities
,
periapical granuloma
,
gastrointestinal microbiome
,
atopic dermatitis
,
eczema
,
alzheimer disease
,
neuroimaging
,
cognitive dysfunction
,
functional food
,
irritable bowel syndrome
,
nutrition therapy
,
resistance training
,
osteosclerosis
,
oral hygiene
,
pelvic pain
,
callosities
,
metatarsalgia
,
solid-state lasers
,
gas lasers
,
lymphadenopathy
,
accessory nerve injuries
,
paresthesia
,
replacement arthroplasty knee
,
neurogenic urinary bladder
,
hypospadias
,
spinal dysraphism
,
bladder exstrophy
,
sleep quality
,
epiretinal membrane
,
retinal perforations
,
gastrointestinal neoplasms
,
asthma
,
airway remodeling
,
dehydration
,
periapical diseases
,
barrett esophagus
,
keratectomy
,
venous thrombosis
,
rectal prolapse
,
nonpenetrating wounds
,
lung neoplasms
,
chronic obstructive pulmonary disease
,
pneumonia
,
bacterial pneumonia
,
tissue transplantation
,
spinal stenosis
,
radiculopathy
,
abdominal hernia
,
internal hernia
,
strabismus
,
exotropia
,
gynatresia
,
tooth injuries
,
bone neoplasms
,
maxillofacial abnormalities
,
jaw fractures
,
dentofacial deformities
,
dilated cardiomyopathy
,
dental fistula
,
congenital hip dislocation
,
hip dislocation
,
developmental dysplasia of the hip
,
acquired joint deformities
,
clubfoot
,
equinus deformity
,
talipes
,
intra-articular fractures
,
fracture fixation
,
non-therapeutic body modification
,
cystocele
,
vesico-ureteral reflux
,
uterine prolapse
,
developmental bone diseases
,
nail-patella syndrome
,
facial expression
,
back pain
,
root planing
,
ischemic stroke
,
male breast neoplasms
,
female urogenital diseases
,
joint instability
,
tooth abrasion
,
cerebrovascular disorders
,
stomach neoplasms
,
spondylolisthesis
,
may-thurner syndrome
,
sleep wake disorders
,
dyssomnias
,
parasomnias
,
goiter
,
glucose metabolism disorders
,
lipid metabolism
,
autonomic nervous system diseases
,
zika virus infection
,
recovery of function
,
lasers
,
keratoconjunctivitis
,
infectious keratoconjunctivitis
,
traumatic dental occlusion
,
gender identity
,
crush injuries
,
tendon injuries
,
muscle hypertonia
,
dentin sensitivity
,
intracranial aneurysm
,
cerebellar neoplasms
,
cerebral ventricle neoplasms
,
femoracetabular impingement
,
tuberous sclerosis
,
lymphangioleiomyomatosis
,
lacerations
,
acute pain
,
healthy aging
,
oral hemorrhage
,
digestive system diseases
,
mast cell activation syndrome
,
bursitis
,
hip fractures
,
plastic surgery procedures
,
dental pulp diseases
,
cleft palate
,
jaw cysts
,
uterine hemorrhage
,
hypoxia
,
breast diseases
,
dentin dysplasia
,
patellar dislocation
,
bacterial vaginosis
,
vaginitis
,
blood coagulation disorders
,
hemostatic disorders
,
connective and soft tissue neoplasms
,
systolic heart failure
,
thrombasthenia
,
cri-du-chat syndrome
,
bone transplantation
,
vitamin d deficiency
,
shoulder pain
,
scheuermann disease
,
spinal osteochondrosis
,
cone-beam computed tomography
,
endometriosis
,
humans
,
dental occlusion
,
muscle diastasis
,
vascular malformations
,
lipedema
,
nephritis
,
hallux rigidus
,
hallux limitus
,
neuromuscular diseases
,
lambert-eaton myasthenic syndrome
,
congenital myasthenic syndromes
,
fatigue
,
paranasal sinus diseases
,
hypocalcemia
,
equipment and supplies
,
bariatric surgery
,
skin physiological phenomena
,
randomized controlled trials as topic
,
aneurysm
,
thoracic aortic aneurysm
,
rare diseases
,
aortic aneurysm
,
aortic diseases
,
lymphatic metastasis
,
spondylarthropathies
,
myofascial pain syndromes
,
fibromyalgia
,
hemophilia a
Provisc
knee osteoarthritis
,
osteoarthritis
Articular
joint diseases
,
arthralgia
,
sjogren's syndrome
,
syndrome
,
osteoarthritis
,
knee osteoarthritis
,
rheumatoid arthritis
,
arthritis
,
hemophilia a
,
glycogen storage disease type ii
,
diabetes mellitus
,
hyperglycemia
,
cooperative behavior
,
cartilage diseases
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