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Trade Name	Drug Name	Approved	Patent Expires	Indication
Copiktra	Duvelisib	2018-09-24	2029-2032	B-cell chronic lymphocytic leukemia , Follicular lymphoma
Farydak	Panobinostat	2015-02-23	2028	Multiple myeloma

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

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Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

non-small-cell lung carcinoma

,

liver neoplasms

,

head and neck neoplasms

,

triple negative breast neoplasms

,

castration-resistant prostatic neoplasms

,

myeloproliferative disorders

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelodysplastic-myeloproliferative diseases

,

,

myeloid leukemia accelerated phase

,

malignant mesothelioma

,

,

hepatocellular carcinoma

,

nasopharyngeal carcinoma

,

,

,

,

,

sickle cell anemia

,

colonic neoplasms

,

rectal neoplasms

,

esophageal neoplasms

,

,

medulloblastoma

,

,

,

breast neoplasms

,

non-hodgkin lymphoma

,

,

prostatic neoplasms

,

,

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

hematologic neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

large b-cell lymphoma diffuse

,

,

diffuse intrinsic pontine glioma

,

b-cell lymphoma

,

t-cell lymphoma cutaneous

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

t-cell leukemia

,

mantle-cell lymphoma

,

,

renal cell carcinoma

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia chronic

,

myeloid leukemia chronic-phase

,

neoplasm metastasis

,

myelomonocytic leukemia juvenile

,

,

extranodal nk-t-cell lymphoma

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

kidney neoplasms

,

waldenstrom macroglobulinemia

,

adult t-cell leukemia-lymphoma

,

brain neoplasms

,

small cell lung carcinoma

,

pancreatic neoplasms

,

,

,

myelomonocytic leukemia acute

,

,

,

sezary syndrome

,

lymphoproliferative disorders

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mycosis fungoides

,

burkitt lymphoma

,

,

essential thrombocythemia

,

,

,

colorectal neoplasms

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell leukemia

,

enteropathy-associated t-cell lymphoma

,

plasma cell leukemia

,

biphenotypic leukemia acute

,

,

stomach neoplasms

,

,

bronchiolitis obliterans syndrome

,

thyroid neoplasms

,

thyroid diseases

,

neuroendocrine tumors

,

thrombocytopenia

,

interdigitating dendritic cell sarcoma

,

,

phenylketonurias

,

,

multiple myeloma

,

,

plasma cell neoplasms

,

myelodysplastic syndromes

,

hodgkin disease

,

,

myeloid leukemia acute

,

myeloid leukemia

,

primary myelofibrosis

,

graft vs host disease

,

polycythemia vera

,

,

non-hodgkin lymphoma

,

,

multiple myeloma

,

hodgkin disease

,

plasma cell neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

large-cell lymphoma anaplastic

,

lymphoid leukemia

,

,

b-cell chronic lymphocytic leukemia

,

reactive arthritis

,

,

,

,

head and neck neoplasms

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

small cell lung carcinoma

,

,

,

urinary bladder neoplasms

,

esophageal squamous cell carcinoma

,

triple negative breast neoplasms

,

malignant mesothelioma

,

breast neoplasms

,

,

colorectal neoplasms

,

pancreatic neoplasms

,

tumor virus infections

,

non-small-cell lung carcinoma

,

,

,

b-cell lymphoma marginal zone

,

t-cell lymphoma cutaneous

,

pancreatic neoplasms

,

non-small-cell lung carcinoma

,

,

,

diffuse intrinsic pontine glioma

,

multiple myeloma

,

,

brain neoplasms

,

,

plasma cell neoplasms

,

,

brain neoplasms

,

nutritional status

,

,

pneumococcal pneumonia

,

,

male breast neoplasms

,

respiratory tract infections

,

embryo transfer

,

,

,

,

postpartum hemorrhage

,

inflammatory bowel diseases

,

,

tendon injuries

,

,

community-acquired infections

,

haemophilus influenzae

,

streptococcus pneumoniae

,

prostatic neoplasms

,

cytomegalovirus infections

,

,

energy metabolism

,

ovarian epithelial carcinoma

,

head and neck neoplasms

,

stomach neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

neoplasms by site

,

non-small-cell lung carcinoma

,

,

,

falciparum malaria

,

ovarian neoplasms

,

renal cell carcinoma

,

,

healthy volunteers/patients

,

colorectal neoplasms

,

,

,

multiple myeloma

,

plasma cell neoplasms

,

pancreatic neoplasms

,

uterine cervical neoplasms

,

,

type 1 diabetes mellitus

,

sickle cell anemia

,

sjogren's syndrome

,

,

,

respiration disorders

,

chronic hepatitis b

,

,

endometrial neoplasms

,

,

malignant mesothelioma

,

squamous cell carcinoma of head and neck

,

cutaneous malignant melanoma

,

streptococcus agalactiae

,

follicular lymphoma

,

microsatellite repeats

,

small cell lung carcinoma

,

macular degeneration

,

b-cell lymphoma

,

,

,

respiratory tract diseases

,

,

focal segmental glomerulosclerosis

,

chronic hepatitis

,

membranous glomerulonephritis

,

nephrotic syndrome

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

systemic scleroderma

,

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

,

,

,

kidney transplantation

,

,

,

,

b-cell chronic lymphocytic leukemia

,

beta-thalassemia

,

,

sickle cell trait

,

,

,

clear cell adenocarcinoma

,

large cell carcinoma

,

vaginal neoplasms

,

vulvar neoplasms

,

adenomyoepithelioma

,

breast neoplasms

,

,

rheumatoid arthritis

,

,

haemophilus influenzae type b

,

haemophilus infections

,

chronic renal insufficiency

,

,

neisseria meningitidis

,

respiratory syncytial virus infections

,

streptococcal infections

,

,

muscle spasticity

,

kidney diseases

,

postmenopausal osteoporosis

,

non-hodgkin lymphoma

,

,

human influenza

,

,

insulin resistance

,

,

pneumococcal infections

,

thrombocytopenic purpura idiopathic

,

inflammatory breast neoplasms

,

,

ductal carcinoma breast

,

,

,

abdominal obesity

,

,

,

,

chronic kidney failure

,

,

large b-cell lymphoma diffuse

,

,

renal insufficiency

,

systemic lupus erythematosus

,

myocardial infarction

,

st elevation myocardial infarction

,

acute coronary syndrome

,

,

,

left ventricular hypertrophy

,

rotavirus infections

,

,

,

meningococcal infections

,

,

mucinous adenocarcinoma

,

,

meningococcal meningitis

,

,

thrombocytopenia

,

respiratory syncytial viruses

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

,

,

chronic obstructive pulmonary disease

,

acquired immunodeficiency syndrome

,

,

,

,

,

metabolic bone diseases

,

obstructive lung diseases

,

pulmonary eosinophilia

,

,

,

chronic bronchitis

,

,

chronic disease

,

growth and development

,

,

,

immunologic tests

,

,

alzheimer disease

,

cardiovascular diseases

,

wasting syndrome

,

,

lipid metabolism

,

resistance training

,

,

,

major depressive disorder

,

depressive disorder

,

,

allergic rhinitis seasonal

,

clostridioides difficile

Microcrystalline cellulose

,

muscular atrophy

,

,

,

hiv-associated lipodystrophy syndrome

,

colorectal neoplasms

,

,

chronic obstructive pulmonary disease

,

ulcerative colitis

,

,

,

respiratory tract diseases

,

respiration disorders

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

,

,

healthy volunteers/patients

,

,

human influenza

,

,

falciparum malaria

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

non-hodgkin lymphoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

prehypertension

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

neisseria meningitidis

,

haemophilus infections

,

,

type 2 diabetes mellitus

,

,

,

diabetes mellitus

,

acquired immunodeficiency syndrome

,

,

immunologic deficiency syndromes

,

,

communicable diseases

,

,

,

,

haemophilus influenzae type b

,

,

renal insufficiency

,

,

,

,

,

,

chronic hepatitis b

,

,

chronic hepatitis

,

,

immunologic tests

Globulin, immune

hematologic neoplasms

,

,

pancreatic ductal carcinoma

,

neurofibromatosis 1

,

hereditary sensory and autonomic neuropathies

,

multiple sclerosis

,

thyroid neoplasms

,

,

myelodysplastic syndromes

,

myeloproliferative disorders

,

b-cell chronic lymphocytic leukemia

,

small cell lung carcinoma

,

t-cell lymphoma cutaneous

,

,

merkel cell carcinoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

retinal detachment

,

vascular diseases

,

wet macular degeneration

,

polypoidal choroidal vasculopathy

,

atopic dermatitis

,

,

,

pancreatic neoplasms

,

esophageal squamous cell carcinoma

,

,

,

head and neck neoplasms

,

liver neoplasms

,

ovarian neoplasms

,

hepatocellular carcinoma

,

,

hodgkin disease

,

urologic neoplasms

,

prostatic neoplasms

,

,

neoplasm metastasis

,

,

transitional cell carcinoma

,

triple negative breast neoplasms

,

,

,

myeloid leukemia

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

mycosis fungoides

,

esophageal neoplasms

,

macular degeneration

,

ovarian epithelial carcinoma

,

brain neoplasms

,

endometrial neoplasms

,

invasive hydatidiform mole

,

,

diabetes mellitus

,

diabetic retinopathy

,

disease progression

,

male breast neoplasms

,

dermatomyositis

,

hypercholesterolemia

,

interstitial cystitis

,

,

,

postherpetic neuralgia

,

neoadjuvant therapy

,

waldenstrom macroglobulinemia

,

kidney diseases

,

urologic diseases

,

neoplasms by site

,

glandular and epithelial neoplasms

,

,

monocytic leukemia acute

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

hematopoietic stem cell transplantation

,

stomach neoplasms

,

discoid lupus erythematosus

,

cutaneous lupus erythematosus

,

,

chronic hepatitis b

,

persistent infection

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

neurofibromatoses

,

,

systemic scleroderma

,

,

diffuse scleroderma

,

meningeal neoplasms

,

colorectal neoplasms

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

myeloid leukemia acute

,

renal cell carcinoma

,

plasma cell neoplasms

,

,

alzheimer disease

,

squamous cell carcinoma of head and neck

,

,

non-hodgkin lymphoma

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

colonic neoplasms

,

urinary bladder neoplasms

,

knee osteoarthritis

,

squamous cell carcinoma

,

rectal neoplasms

,

kidney neoplasms

,

follicular lymphoma

,

juvenile arthritis

,

,

lymphoid leukemia

,

squamous cell neoplasms

,

meningococcal infections

,

non-muscle invasive bladder neoplasms

,

aplastic anemia

,

rectal diseases

,

urogenital neoplasms

,

hip osteoarthritis

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

gastrointestinal diseases

,

intestinal neoplasms

,

digestive system diseases

,

colonic diseases

,

intestinal diseases

,

,

,

bronchiolitis obliterans syndrome

,

adenosquamous carcinoma

,

large cell carcinoma

,

,

,

antibody formation

,

hematologic diseases

,

kidney transplantation

,

residual neoplasm

,

cardiovascular diseases

,

small cell carcinoma

,

rheumatoid arthritis

,

,

multiple myeloma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

healthy volunteers/patients

,

,

ankylosing spondylitis

,

psoriatic arthritis

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

ulcerative colitis

,

tick-borne encephalitis

,

,

pharmacokinetics

,

,

spondylarthritis

,

axial spondyloarthritis

,

pneumococcal infections

,

,

non-radiographic axial spondyloarthritis

,

electrocardiography

,

,

rheumatic fever

,

papulosquamous skin diseases

,

inflammatory bowel diseases

,

spondylarthropathies

,

rheumatic diseases

,

,

meningococcal meningitis

,

,

vaccine immunogenicity

,

Potassium magnesium citrate (4:1:2)

healthy volunteers/patients

,

gram-positive bacterial infections

,

non-small-cell lung carcinoma

,

pancreatic neoplasms

,

stomach neoplasms

,

ovarian neoplasms

,

,

,

hepatic insufficiency

,

,

,

renal insufficiency

,

,

,

wound infection

,

,

,

small cell lung carcinoma

,

,

cytomegalovirus infections

,

hodgkin disease

,

,

breast neoplasms

,

non-hodgkin lymphoma

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

gestational diabetes

,

b-cell chronic lymphocytic leukemia

,

pneumococcal pneumonia

,

pneumococcal infections

,

,

communicable diseases

,

bacterial skin diseases

,

insulin resistance

,

chronic renal insufficiency

,

bacterial infections

,

,

acquired immunodeficiency syndrome

,

antibiotic prophylaxis

,

,

islets of langerhans transplantation

,

hyperlipidemias

,

chronic kidney failure

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

prediabetic state

,

,

glucose intolerance

,

,

,

hospitalization

,

,

atherosclerosis

,

adipose tissue neoplasms

,

,

,

,

cystic fibrosis

,

,

type 1 diabetes mellitus

,

cardiovascular diseases

Potassium nitrate

,

actinic keratosis

,

,

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

pharmacokinetics

,

hematologic neoplasms

,

,

parotid neoplasms

,

medical sociology

,

thrombocytopenia

,

connective and soft tissue neoplasms

,

paraneoplastic syndromes

,

,

renal insufficiency

,

papillary thyroid cancer

,

medullary carcinoma

,

follicular adenocarcinoma

,

vaginal neoplasms

,

vulvar neoplasms

,

,

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mantle-cell lymphoma

,

large b-cell lymphoma diffuse

,

,

burkitt lymphoma

,

,

large-cell lymphoma immunoblastic

,

choroid plexus neoplasms

,

craniopharyngioma

,

oligodendroglioma

,

primitive neuroectodermal tumors

,

,

appendiceal neoplasms

,

subependymal glioma

,

,

,

colorectal neoplasms

,

,

liver neoplasms

,

,

biliary tract neoplasms

,

thyroid neoplasms

,

malignant pleural effusion

,

kidney neoplasms

,

gallbladder neoplasms

,

colonic neoplasms

,

cholangiocarcinoma

,

,

adenosquamous carcinoma

,

disease progression

,

gastrointestinal stromal tumors

,

,

primitive neuroectodermal tumors peripheral

,

,

hepatocellular carcinoma

,

,

,

,

hemangiosarcoma

,

brain neoplasms

,

,

hyperthermic intraperitoneal chemotherapy

,

,

,

,

synovial sarcoma

,

urogenital neoplasms

,

thymus neoplasms

,

multiple myeloma

,

alopecia areata

,

,

residual neoplasm

,

rectal neoplasms

,

merkel cell carcinoma

,

myeloid leukemia acute

,

,

carcinoma in situ

,

breast carcinoma in situ

,

testicular neoplasms

,

,

,

cutaneous malignant melanoma

,

papillomaviridae

,

,

pleural effusion

,

anaplastic thyroid carcinoma

,

thyroid diseases

,

,

cognitive dysfunction

,

myeloproliferative disorders

,

lymphatic metastasis

,

lacrimal apparatus diseases

,

adrenocortical carcinoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

medulloblastoma

,

,

,

,

heavy ion radiotherapy

,

microsatellite instability

,

germ cell and embryonal neoplasms

,

branchio-oto-renal syndrome

,

,

,

,

somatoform disorders

,

disseminated intravascular coagulation

,

tonsillar neoplasms

,

glandular and epithelial neoplasms

,

,

cardiovascular diseases

,

intraductal carcinoma noninfiltrating

,

antineoplastic combined chemotherapy protocols

,

urologic diseases

,

urinary bladder diseases

,

,

papillomavirus infections

,

neurofibrosarcoma

,

hereditary sensory and autonomic neuropathies

,

prostatic hyperplasia

,

,

bone marrow diseases

,

epstein-barr virus infections

,

endophthalmitis

,

,

,

hormone-dependent neoplasms

,

ampulla of vater cancer

,

gastrointestinal diseases

,

ductal carcinoma

,

,

,

mediastinal neoplasms

,

palliative care

,

pancoast syndrome

,

penile neoplasms

,

inborn genetic diseases

,

thromboembolism

,

myelodysplastic syndromes

,

precancerous conditions

,

plasma cell neoplasms

,

,

,

,

central nervous system neoplasms

,

adenoid cystic carcinoma

,

alphapapillomavirus

,

carcinoid tumor

,

,

pancreatic ductal carcinoma

,

hodgkin disease

,

malignant mesothelioma

,

dna repair-deficiency disorders

,

adolescent development

,

,

cancer vaccines

,

radiation effects

,

perioperative period

,

,

pathologic complete response

,

maxillary sinus neoplasms

,

,

ovarian neoplasms

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

ovarian epithelial carcinoma

,

,

pancreatic neoplasms

,

,

esophageal squamous cell carcinoma

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

adenocarcinoma of lung

,

urologic neoplasms

,

fallopian tube neoplasms

,

small cell lung carcinoma

,

uterine cervical neoplasms

,

salivary gland neoplasms

,

endometrial neoplasms

,

renal cell carcinoma

,

oropharyngeal neoplasms

,

,

laryngeal neoplasms

,

,

inflammatory breast neoplasms

,

peritoneal neoplasms

,

,

hypopharyngeal neoplasms

,

neoadjuvant therapy

,

non-muscle invasive bladder neoplasms

,

mouth neoplasms

,

chemotherapy-induced febrile neutropenia

,

bronchiolo-alveolar adenocarcinoma

,

invasive hydatidiform mole

,

tongue neoplasms

,

hypersensitivity

,

febrile neutropenia

,

olfactory esthesioneuroblastoma

,

,

,

drug-related side effects and adverse reactions

,

gastrointestinal neoplasms

,

breast diseases

,

laryngeal diseases

,

urethral neoplasms

,

malignant fibrous histiocytoma

,

unknown primary neoplasms

,

brain stem neoplasms

,

small cell carcinoma

,

paranasal sinus neoplasms

,

endometrioid carcinoma

,

large cell carcinoma

,

,

hereditary breast and ovarian cancer syndrome

,

uterine neoplasms

,

disease-free survival

,

circulating neoplastic cells

,

verrucous carcinoma

,

,

cystadenocarcinoma

,

ductal carcinoma breast

,

digestive system neoplasms

,

chemoradiotherapy

,

bronchogenic carcinoma

,

rhabdomyosarcoma

,

dermatofibrosarcoma

,

lobular carcinoma

,

mucinous cystadenocarcinoma

,

mucinous adenocarcinoma

,

serous cystadenocarcinoma

,

clear cell adenocarcinoma

,

neoplasms by site

,

local neoplasm recurrence

,

neuroendocrine carcinoma

,

ureteral neoplasms

,

bronchial neoplasms

,

neurotoxicity syndromes

,

healthy volunteers/patients

,

,

,

progression-free survival

,

postoperative complications

,

,

acinar cell carcinoma

,

,

induction chemotherapy

,

respiratory tract diseases

,

respiratory tract neoplasms

,

genetic predisposition to disease

,

,

pharyngeal neoplasms

,

,

,

therapeutic equivalency

,

adenomyoepithelioma

,

patient preference

,

,

directly observed therapy

,

alveolar rhabdomyosarcoma

,

embryonal rhabdomyosarcoma

,

x-linked bulbo-spinal atrophy

,

breast neoplasms

,

non-small-cell lung carcinoma

,

prostatic neoplasms

,

,

,

stomach neoplasms

,

squamous cell carcinoma of head and neck

,

,

head and neck neoplasms

,

neoplasm metastasis

,

esophageal neoplasms

,

squamous cell carcinoma

,

castration-resistant prostatic neoplasms

,

triple negative breast neoplasms

,

squamous cell neoplasms

,

male breast neoplasms

,

,

peripheral nervous system diseases

,

,

,

second primary neoplasms

,

thoracic neoplasms

,

chemical and drug induced liver injury

,

meningeal carcinomatosis

,

,

,

,

,

,

,

breast cancer lymphedema

,

taste disorders

,

,

,

,

,

prospective studies

,

pharmacogenomic testing

,

,

chemotherapy-related cognitive impairment

,

,

,

,

postoperative pain

,

,

,

postpartum depression

,

,

depressive disorder

,

,

hand-foot syndrome

,

intravesical administration

,

mycobacterium bovis

,

pseudomyxoma peritonei

breast neoplasms

,

,

triple negative breast neoplasms

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