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Trade Name	Drug Name	Approved	Patent Expires	Indication
Copiktra	Duvelisib	2018-09-24	2029-2032	B-cell chronic lymphocytic leukemia , Follicular lymphoma
Farydak	Panobinostat	2015-02-23	2028	Multiple myeloma

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

non-small-cell lung carcinoma

,

liver neoplasms

,

head and neck neoplasms

,

triple negative breast neoplasms

,

castration-resistant prostatic neoplasms

,

myeloproliferative disorders

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia accelerated phase

,

malignant mesothelioma

,

,

hepatocellular carcinoma

,

nasopharyngeal carcinoma

,

,

,

,

,

sickle cell anemia

,

beta-thalassemia

,

colonic neoplasms

,

rectal neoplasms

,

esophageal neoplasms

,

,

medulloblastoma

,

,

,

myeloid leukemia

,

breast neoplasms

,

non-hodgkin lymphoma

,

,

prostatic neoplasms

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

hematologic neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

,

large b-cell lymphoma diffuse

,

diffuse intrinsic pontine glioma

,

b-cell lymphoma

,

t-cell lymphoma cutaneous

,

b-cell chronic lymphocytic leukemia

,

t-cell leukemia

,

mantle-cell lymphoma

,

,

,

renal cell carcinoma

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia chronic

,

myeloid leukemia chronic-phase

,

neoplasm metastasis

,

,

lymphoid leukemia

,

extranodal nk-t-cell lymphoma

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

kidney neoplasms

,

waldenstrom macroglobulinemia

,

adult t-cell leukemia-lymphoma

,

,

brain neoplasms

,

small cell lung carcinoma

,

pancreatic neoplasms

,

,

,

myelomonocytic leukemia acute

,

myelomonocytic leukemia juvenile

,

,

,

sezary syndrome

,

lymphoproliferative disorders

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mycosis fungoides

,

burkitt lymphoma

,

,

essential thrombocythemia

,

,

,

colorectal neoplasms

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell leukemia

,

enteropathy-associated t-cell lymphoma

,

plasma cell leukemia

,

biphenotypic leukemia acute

,

,

stomach neoplasms

,

,

thyroid neoplasms

,

thyroid diseases

,

neuroendocrine tumors

,

thrombocytopenia

,

interdigitating dendritic cell sarcoma

,

,

phenylketonurias

,

,

multiple myeloma

,

,

plasma cell neoplasms

,

myelodysplastic syndromes

,

hodgkin disease

,

,

myeloid leukemia acute

,

primary myelofibrosis

,

graft vs host disease

,

polycythemia vera

,

bronchiolitis obliterans syndrome

,

healthy volunteers/patients

,

b-cell lymphoma

,

large b-cell lymphoma diffuse

,

extranodal nk-t-cell lymphoma

,

adult t-cell leukemia-lymphoma

,

t-cell leukemia

,

sezary syndrome

,

mycosis fungoides

,

,

,

hepatic insufficiency

,

multiple myeloma

,

hodgkin disease

,

plasma cell neoplasms

,

large-cell lymphoma anaplastic

,

t-cell lymphoma

,

,

hematologic neoplasms

,

reactive arthritis

,

enteropathy-associated t-cell lymphoma

,

head and neck neoplasms

,

squamous cell carcinoma of head and neck

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

prolymphocytic leukemia t-cell

,

large granular lymphocytic leukemia

,

rheumatoid arthritis

,

,

coronavirus infections

,

,

,

prolymphocytic leukemia

,

t-cell lymphoma cutaneous

,

,

b-cell chronic lymphocytic leukemia

,

non-hodgkin lymphoma

,

follicular lymphoma

,

t-cell lymphoma peripheral

,

,

lymphoid leukemia

,

b-cell lymphoma marginal zone

,

,

immunoblastic lymphadenopathy

,

hereditary sensory and autonomic neuropathies

anxiety disorders

,

healthy volunteers/patients

,

huntington disease

,

non-alcoholic fatty liver disease

,

,

,

,

,

breast neoplasms

,

patient compliance

,

,

chronic hepatitis b

,

chronic hepatitis

,

parkinson disease

,

eosinophilic esophagitis

,

,

biliary liver cirrhosis

,

,

,

pulmonary hypertension

,

pulmonary arterial hypertension

,

diffuse scleroderma

,

,

,

,

short bowel syndrome

,

myocardial infarction

,

drug resistance

,

heat stress disorders

,

,

combat disorders

,

traumatic stress disorders

,

gastrointestinal diseases

,

,

intestinal diseases

,

knee osteoarthritis

,

,

,

musculoskeletal diseases

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

depressive disorder

,

,

major depressive disorder

,

,

,

,

,

kidney diseases

,

,

cardiovascular diseases

,

chronic renal insufficiency

,

chronic hepatitis c

,

papillomavirus infections

,

,

,

pulmonary embolism

,

,

thromboembolism

,

,

venous thrombosis

,

,

papillomavirus vaccines

,

,

meningococcal infections

,

,

glucose metabolism disorders

,

metabolic diseases

,

vascular diseases

,

,

metabolic syndrome

,

endocrine system diseases

,

hypertriglyceridemia

,

rheumatoid arthritis

,

atrial fibrillation

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

systemic scleroderma

,

juvenile arthritis

,

behcet syndrome

,

dermatomyositis

,

ankylosing spondylitis

,

sjogren's syndrome

,

systemic lupus erythematosus

,

,

spondylarthritis

,

systemic vasculitis

,

diabetic neuropathies

,

hypercholesterolemia

,

,

facial nerve diseases

,

,

wasting syndrome

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

renal cell carcinoma

,

urologic neoplasms

,

,

endometrial neoplasms

,

head and neck neoplasms

,

non-hodgkin lymphoma

,

,

hodgkin disease

,

small cell carcinoma

,

,

squamous cell carcinoma

,

merkel cell carcinoma

,

malignant mesothelioma

,

,

non-small-cell lung carcinoma

,

,

neoplasm metastasis

brain neoplasms

,

,

,

diffuse intrinsic pontine glioma

multiple myeloma

,

b-cell chronic lymphocytic leukemia

,

plasma cell neoplasms

,

hodgkin disease

,

,

breast neoplasms

,

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

non-hodgkin lymphoma

,

mantle-cell lymphoma

,

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

pharmacokinetics

,

inflammatory breast neoplasms

,

,

renal cell carcinoma

,

communicable diseases

,

pneumococcal infections

,

immune system diseases

,

triple negative breast neoplasms

,

,

,

,

,

,

,

oligodendroglioma

,

small cell lung carcinoma

,

neoplasm metastasis

,

stomach neoplasms

,

esophageal neoplasms

,

hodgkin disease

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

bronchiolitis obliterans syndrome

,

,

squamous cell carcinoma of head and neck

,

ovarian epithelial carcinoma

,

plasma cell neoplasms

,

human influenza

,

fallopian tube neoplasms

,

biliary tract neoplasms

,

prolymphocytic leukemia

,

pancreatic neoplasms

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

head and neck neoplasms

,

pancreatic ductal carcinoma

,

induction chemotherapy

,

,

adenocarcinoma of lung

,

gestational diabetes

,

pregnancy in diabetics

,

coronary disease

,

large b-cell lymphoma diffuse

,

brain neoplasms

,

mucopolysaccharidoses

,

mucopolysaccharidosis i

,

follicular lymphoma

,

hematopoietic stem cell transplantation

,

peripheral arterial disease

,

atherosclerosis

,

intermittent claudication

,

peripheral vascular diseases

,

,

,

,

,

meningococcal meningitis

,

haemophilus infections

,

cutaneous malignant melanoma

,

esophageal squamous cell carcinoma

,

urinary bladder neoplasms

,

,

rectal neoplasms

,

congenital abnormalities

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

erythroblastic leukemia acute

,

hypersensitivity

,

peanut hypersensitivity

,

squamous cell carcinoma

,

squamous cell neoplasms

,

prolymphocytic leukemia t-cell

,

allergic rhinitis

,

,

acquired immunodeficiency syndrome

,

sezary syndrome

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

pulmonary alveolar proteinosis

,

,

t-cell lymphoma peripheral

,

laryngeal neoplasms

,

,

alpha 1-antitrypsin deficiency

,

breast neoplasms

,

colorectal neoplasms

,

multiple myeloma

,

non-small-cell lung carcinoma

,

,

myeloid leukemia acute

,

b-cell chronic lymphocytic leukemia

,

,

,

,

myelodysplastic syndromes

,

,

ovarian neoplasms

,

,

,

graft vs host disease

,

meningococcal infections

,

,

healthy volunteers/patients

,

,

hematologic neoplasms

,

,

pneumococcal pneumonia

,

,

haemophilus influenzae type b

,

,

myeloid leukemia

,

,

venous thrombosis

,

rheumatoid arthritis

,

,

bcr-abl positive chronic myelogenous leukemia

,

aplastic anemia

,

thrombotic thrombocytopenic purpura

,

,

neuroendocrine tumors

,

carcinoid tumor

,

,

paraneoplastic syndromes

,

islet cell carcinoma

,

islet cell adenoma

,

,

,

somatostatinoma

,

pulmonary embolism

,

,

,

st elevation myocardial infarction

,

glucose intolerance

,

hematologic diseases

,

inborn genetic diseases

,

blood coagulation disorders

,

x-linked genetic diseases

,

hemorrhagic disorders

,

inherited blood coagulation disorders

,

coagulation protein disorders

,

fetal growth retardation

,

thromboembolism

,

noonan syndrome

,

bacterial meningitis

,

,

myeloproliferative disorders

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

,

type 2 diabetes mellitus

,

type 1 diabetes mellitus

,

glycogen storage disease type ii

,

,

diabetes mellitus

,

prostatic neoplasms

,

non-hodgkin lymphoma

,

multiple sclerosis

,

,

glycogen storage disease type iii

,

relapsing-remitting multiple sclerosis

,

graft rejection

,

,

,

chronic kidney failure

,

insulin resistance

,

renal insufficiency

,

kidney transplantation

,

autologous transplantation

,

acute coronary syndrome

,

myocardial infarction

,

,

,

liver transplantation

,

psychology rejection

,

atrial fibrillation

,

,

,

,

,

,

,

,

,

inferior wall myocardial infarction

,

kidney diseases

,

coronary artery disease

,

immunosuppression therapy

,

,

,

glycogen storage disease

,

,

lymphoproliferative disorders

,

paraproteinemias

,

heart transplantation

,

reperfusion injury

Globulin, immune

healthy volunteers/patients

,

myeloid leukemia

,

head and neck neoplasms

,

myelodysplastic syndromes

,

,

uveal neoplasms

,

cutaneous malignant melanoma

,

,

endometrial neoplasms

,

,

,

multiple myeloma

,

mantle-cell lymphoma

,

,

esophageal neoplasms

,

,

,

biliary tract neoplasms

,

plasma cell neoplasms

,

choroidal neovascularization

,

,

waldenstrom macroglobulinemia

,

b-cell lymphoma marginal zone

,

aids-related lymphoma

,

bronchiolitis obliterans syndrome

,

unknown primary neoplasms

,

genomic instability

,

type 1 diabetes mellitus

,

cholangiocarcinoma

,

meningeal carcinomatosis

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

vascular graft occlusion

,

margins of excision

,

,

hemolytic-uremic syndrome

,

thrombotic thrombocytopenic purpura

,

thrombocytopenic purpura

,

,

,

behcet syndrome

,

extranodal nk-t-cell lymphoma

,

hereditary sensory and autonomic neuropathies

,

graft vs host disease

,

castleman disease

,

,

systemic lupus erythematosus

,

sjogren's syndrome

,

diabetic nephropathies

,

,

renal hypertension

,

diabetes mellitus

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

central nervous system neoplasms

,

nervous system neoplasms

,

pathologic neovascularization

,

burkitt lymphoma

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

sex cord-gonadal stromal tumors

,

interstitial lung diseases

,

erythema multiforme

,

reactive arthritis

,

immunoblastic lymphadenopathy

,

,

myasthenia gravis

,

neuroendocrine carcinoma

,

cytokine release syndrome

,

,

thoracic neoplasms

,

,

large b-cell lymphoma diffuse

,

liver neoplasms

,

b-cell lymphoma

,

follicular lymphoma

,

hepatocellular carcinoma

,

rectal neoplasms

,

triple negative breast neoplasms

,

,

renal cell carcinoma

,

neoplasm metastasis

,

macular degeneration

,

,

,

pancreatic neoplasms

,

,

,

small cell lung carcinoma

,

colonic neoplasms

,

ovarian epithelial carcinoma

,

urinary bladder neoplasms

,

,

esophageal squamous cell carcinoma

,

uterine cervical neoplasms

,

urologic neoplasms

,

transitional cell carcinoma

,

inflammatory breast neoplasms

,

ulcerative colitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

brain neoplasms

,

myeloid leukemia acute

,

prostatic neoplasms

,

thrombocytopenic purpura idiopathic

,

,

circulating neoplastic cells

,

malignant mesothelioma

,

diabetic retinopathy

,

multiple sclerosis

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

hematologic neoplasms

,

,

,

iga glomerulonephritis

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

castration-resistant prostatic neoplasms

,

retinal diseases

,

vision disorders

,

,

,

chronic progressive multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

neuromyelitis optica

,

myelin oligodendrocyte glycoprotein antibody-associated disease

,

guillain-barre syndrome

,

patient preference

,

lymphoproliferative disorders

,

neoplasms by histologic type

,

neoplasms by site

,

salivary gland neoplasms

,

,

gallbladder neoplasms

,

,

systemic vasculitis

,

disability evaluation

,

cognition disorders

,

,

hemolytic anemia autoimmune

,

malignant pleural effusion

,

nephrotic syndrome

,

focal segmental glomerulosclerosis

,

lipoid nephrosis

,

ankylosing spondylitis

,

retinal neovascularization

,

membranous glomerulonephritis

,

breast neoplasms

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

,

rheumatoid arthritis

,

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

,

lymphoid leukemia

,

ovarian neoplasms

,

stomach neoplasms

,

kidney transplantation

,

chronic kidney failure

,

granulomatosis with polyangiitis

,

,

microscopic polyangiitis

,

fallopian tube neoplasms

,

heart transplantation

,

kidney diseases

,

peritoneal neoplasms

,

pulmonary fibrosis

,

immunosuppression therapy

,

graft rejection

,

,

transplantation

,

renal insufficiency

,

food hypersensitivity

,

,

,

,

,

adenocarcinoma of lung

,

,

retinal vein occlusion

,

,

antiphospholipid syndrome

,

,

,

severe acute respiratory syndrome

,

communicable diseases

,

,

,

acquired immunodeficiency syndrome

,

neoadjuvant therapy

,

molecular targeted therapy

,

liver cirrhosis

,

atopic dermatitis

prostatic neoplasms

,

breast neoplasms

,

ovarian neoplasms

,

non-small-cell lung carcinoma

,

stomach neoplasms

,

head and neck neoplasms

,

esophageal neoplasms

,

,

urinary bladder neoplasms

,

small cell lung carcinoma

,

endophthalmitis

,

lacrimal apparatus diseases

,

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