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Company ReportsOrexigen Therapeutics

Orexigen Therapeutics(OREX)

Orexigen Therapeutics is a public American pharmaceutical company focused on development of treatments for obesity. The company is based in La Jolla, California and was established by Eckard Weber in 2002. As a public company, Orexigen is traded on the NASDAQ exchange under the stock symbol OREX.

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Mysimba	Bupropion, Naltrexone	2015-03-26	2024-2043	Obesity , Alcoholism , Opioid-related disorders , Tobacco use disorder , Overweight , Drug overdose , Attention deficit disorder with hyperactivity , Depressive disorder , Cough

Clinical Trials

Therapeutic Areas:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

,

depressive disorder

,

tobacco use disorder

,

obsessive-compulsive disorder

,

compulsive personality disorder

,

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

cardiovascular diseases

vitamin d deficiency

,

,

,

body-weight trajectory

,

,

diabetes mellitus

,

metabolic syndrome

,

,

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

atrial fibrillation

,

cardiac arrhythmias

,

depressive disorder

,

tobacco use disorder

,

,

,

type 2 diabetes mellitus

,

diabetes mellitus

intellectual disability

,

tardive dyskinesia

,

,

developmental disabilities

drug interactions

,

pharmacokinetics

,

type 1 diabetes mellitus

,

,

pure autonomic failure

,

,

movement disorders

,

,

,

,

myeloid leukemia acute

,

myeloid leukemia

,

myelodysplastic syndromes

,

,

,

,

,

machiavellianism

,

atopic dermatitis

,

,

drug-induced dyskinesia

,

,

,

stress urinary incontinence

,

fecal incontinence

,

,

phase i metabolic detoxication

,

psychotic affective disorders

,

biological availability

,

cognition disorders

,

,

hepatic insufficiency

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

brain neoplasms

,

non-alcoholic fatty liver disease

,

,

chemical and drug induced liver injury

,

,

,

,

diabetic neuropathies

,

respiratory insufficiency

,

pulmonary arterial hypertension

,

adolescent development

,

alcohol drinking

,

medically unexplained symptoms

,

,

coronavirus infections

,

fragile x syndrome

,

sleep deprivation

,

,

nervous system diseases

,

shy-drager syndrome

,

multiple system atrophy

,

,

binge-eating disorder

,

,

neurodevelopmental disorders

,

,

familial primary pulmonary hypertension

,

non-small-cell lung carcinoma

,

germ cell and embryonal neoplasms

,

,

orthostatic intolerance

,

,

infantile spasms

,

male infertility

,

,

chronic progressive multiple sclerosis

,

prediabetic state

,

glucose intolerance

,

coccidioidomycosis

,

,

,

liver cirrhosis

,

,

biliary liver cirrhosis

,

,

,

subarachnoid hemorrhage

,

hemorrhagic stroke

,

cerebrovascular disorders

,

brain infarction

,

central nervous system diseases

,

,

respiratory aspiration

,

neuroinflammatory diseases

,

,

,

impulsive behavior

,

,

executive function

,

memory disorders

,

neurocognitive disorders

,

,

ventricular remodeling

,

sudden unexpected death in epilepsy

,

microvascular angina

,

klinefelter syndrome

,

,

hypochondriasis

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

olfaction disorders

,

,

pancreatic ductal carcinoma

,

biliary tract neoplasms

,

,

,

,

oxidative stress

,

tuberous sclerosis

,

digeorge syndrome

,

tourette syndrome

,

22q11 deletion syndrome

,

,

frontotemporal lobar degeneration

,

,

,

autistic disorder

,

,

cocaine-related disorders

,

,

premature birth

,

parkinson disease

,

premature ejaculation

,

opioid-related disorders

,

,

hematologic neoplasms

,

,

,

,

,

communicable diseases

,

postoperative nausea and vomiting

,

severe acute respiratory syndrome

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

intellectual disability

,

urinary incontinence

,

,

rheumatoid arthritis

,

,

,

post-acute covid-19 syndrome

,

,

disease progression

,

huntington disease

,

chronic obstructive pulmonary disease

,

,

,

,

,

,

lennox gastaut syndrome

,

chronic hepatitis c

,

stomach neoplasms

,

,

neoplasm metastasis

,

stereotyped behavior

,

,

attempted suicide

,

vascular depression

,

psychological sexual dysfunctions

,

,

,

,

night eating syndrome

,

chronic fatigue syndrome

,

colorectal neoplasms

,

esophageal neoplasms

,

tobacco use disorder

,

central sleep apnea

,

nocturnal enuresis

,

motor disorders

,

,

,

female genital neoplasms

,

reflex epilepsy

,

severe acute respiratory syndrome-related coronavirus

,

psychophysiologic disorders

,

chronic hepatitis

,

aids-related opportunistic infections

,

,

opportunistic infections

,

,

cryptococcal meningitis

,

fungal meningitis

,

non-erosive reflux disease

,

chronic renal insufficiency

,

self-injurious behavior

,

unstable angina

,

pulmonary hypertension

,

temporomandibular joint disorders

,

temporomandibular joint dysfunction syndrome

,

developmental disabilities

,

,

phenylketonurias

,

pancreatic neoplasms

,

bile duct neoplasms

,

liver neoplasms

,

cholangiocarcinoma

,

gallbladder neoplasms

,

radiation injuries

,

hoarding disorder

,

,

cerebral hemorrhage

,

dermatofibrosarcoma

,

,

testicular neoplasms

,

out-of-hospital cardiac arrest

,

post-cardiac arrest syndrome

,

burning mouth syndrome

,

,

child nutrition disorders

,

progression-free survival

,

,

nutrition disorders

,

prosthesis failure

,

wasting syndrome

,

multiple myeloma

,

hematopoietic stem cell transplantation

,

,

depressive disorder

,

major depressive disorder

,

,

anxiety disorders

,

healthy volunteers/patients

,

bipolar disorder

,

psychotic disorders

,

post-traumatic stress disorders

,

obsessive-compulsive disorder

,

compulsive personality disorder

,

traumatic stress disorders

,

,

mental disorders

,

,

,

,

,

,

,

treatment-resistant depressive disorder

,

,

sleep initiation and maintenance disorders

,

cognitive dysfunction

,

diabetes mellitus

,

alzheimer disease

,

,

,

,

psychomotor agitation

,

postpartum depression

,

,

,

,

insulin resistance

,

,

type 2 diabetes mellitus

,

wounds and injuries

,

anorexia nervosa

,

,

,

dysthymic disorder

,

,

,

sleep apnea syndromes

,

personality disorders

,

coronary artery disease

,

myoclonic epilepsies

,

cardiovascular diseases

,

feeding and eating disorders

,

,

borderline personality disorder

,

breast neoplasms

,

,

myofascial pain syndromes

,

substance-related disorders

,

premenstrual syndrome

,

phobic disorders

,

obstructive sleep apnea

,

,

,

physiological sexual dysfunction

,

drug-related side effects and adverse reactions

,

,

problem behavior

,

irritable bowel syndrome

,

ischemic stroke

,

,

attention deficit disorder with hyperactivity

,

,

,

autism spectrum disorder

,

,

,

,

sleep wake disorders

,

,

metabolic syndrome

,

separation anxiety

,

acute coronary syndrome

,

traumatic brain injuries

,

,

,

spinal cord injuries

,

treatment-resistant schizophrenia

,

,

multiple sclerosis

,

,

somatoform disorders

,

,

chronic kidney failure

,

gastroesophageal reflux

,

premenstrual dysphoric disorder

,

,

,

bulimia nervosa

,

marijuana abuse

,

,

,

coronary disease

,

myocardial ischemia

,

myocardial infarction

,

,

,

,

pervasive child development disorders

,

kidney diseases

,

,

conversion disorder

,

dissociative disorders

,

cerebral infarction

,

,

treatment outcome

,

body dysmorphic disorders

,

,

vascular diseases

,

,

schizophrenia spectrum and other psychotic disorders

,

,

suicidal ideation

,

addictive behavior

,

,

migraine disorders

,

psychogenic nonepileptic seizures

,

,

impulse control disruptive and conduct disorders

,

,

neurobehavioral manifestations

,

,

bipolar and related disorders

,

,

,

,

hypersensitivity

,

,

,

,

alcohol-related disorders

,

temporal lobe epilepsy

,

tardive dyskinesia

,

,

compulsive behavior

,

trichotillomania

,

traumatic stress disorders acute

,

drug resistant epilepsy

,

attention deficit and disruptive behavior disorders

,

combat disorders

,

,

,

,

polycystic ovary syndrome

,

,

musculoskeletal diseases

,

childhood schizophrenia

,

postoperative pain

,

,

,

head and neck neoplasms

,

frontotemporal dementia

,

primary progressive aphasia

,

pick disease of the brain

,

vascular dementia

,

pharmacogenomic testing

,

,

,

,

endocrine system diseases

,

relapsing-remitting multiple sclerosis

,

asphyxia neonatorum

,

,

,

oppositional defiant disorder

,

,

friedreich ataxia

,

cerebellar ataxia

,

drug administration schedule

,

parkinsonian disorders

,

,

,

self mutilation

,

cytokine release syndrome

,

,

neuronal plasticity

,

acquired immunodeficiency syndrome

,

,

,

hiv seropositivity

,

overactive urinary bladder

,

,

paranasal sinus diseases

,

,

internet addiction disorder

,

polyneuropathies

,

excoriation disorder

,

replacement arthroplasty knee

,

replacement arthroplasty hip

,

,

,

heart disease risk factors

,

malformations of cortical development

,

,

collective efficacy

,

psychological distress

,

,

,

congenital abnormalities

,

cardiac arrhythmias

,

peptic ulcer hemorrhage

,

,

obstructive lung diseases

,

inborn genetic diseases

,

,

affective symptoms

,

substance withdrawal syndrome

,

emergence delirium

,

adjustment disorders

,

,

,

,

blood coagulation disorders

,

mucocutaneous lymph node syndrome

,

hyperaldosteronism

,

urinary tract infections

,

hyperphosphatemia

,

,

,

bronchopulmonary dysplasia

,

adrenal insufficiency

,

hemostatic disorders

,

coagulation protein disorders

,

secondary prevention

,

,

coronary occlusion

,

coronary thrombosis

,

pathologic constriction

,

spinal stenosis

,

amphetamine-related disorders

,

,

,

paranoid schizophrenia

,

interstitial lung diseases

,

chronic disease

,

acute kidney injury

,

compulsive sexual behavior disorder

,

,

palliative care

,

,

,

hyperlipidemias

,

,

long qt syndrome

,

congenital heart defects

,

sudden death cardiac

,

,

cardiovascular abnormalities

,

romano-ward syndrome

,

pathologic processes

,

,

,

,

peripheral nervous system diseases

,

,

lactic acidosis

,

whiplash injuries

,

fertilization in vitro

,

short bowel syndrome

,

neurodermatitis

,

,

,

peri-implantitis

,

paraphilic disorders

,

local anesthesia

,

,

,

partial epilepsies

,

complex partial epilepsy

,

hypoventilation

,

,

depersonalization

,

sepsis-associated encephalopathy

,

,

aortic valve disease

,

,

asperger syndrome

,

,

acupuncture therapy

,

transcranial magnetic stimulation

,

cognitive behavioral therapy

,

magnetic resonance imaging

,

,

menstrual cycle

,

strongyloidiasis

,

,

intellectual disability

,

tardive dyskinesia

,

,

developmental disabilities

,

non-hodgkin lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

b-cell lymphoma

,

lymphoid leukemia

,

muscular dystrophies

,

,

,

major depressive disorder

,

depressive disorder

,

migraine disorders

,

,

,

cardiovascular diseases

,

coronary disease

,

diabetes mellitus

,

coronary artery disease

,

myocardial ischemia

,

,

peripheral arterial disease

,

peripheral vascular diseases

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