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Nobelpharma

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Hyftor	Sirolimus	2022-03-22	2029-2040	Kidney transplantation , Lymphangioleiomyomatosis , Perivascular epithelioid cell neoplasms , Graft rejection

Clinical Trials

Therapeutic Areas:

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Classification:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

therapeutic equivalency

,

acanthosis nigricans

,

tuberous sclerosis

,

,

,

neurofibromatosis 1

,

neurofibromatoses

,

myelodysplastic syndromes

,

myeloproliferative disorders

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia acute

,

biphenotypic leukemia acute

,

,

eyelid neoplasms

,

myeloid sarcoma

duchenne muscular dystrophy

,

muscular dystrophies

,

,

atopic dermatitis

,

myeloid leukemia acute

,

multiple myeloma

,

,

plasma cell neoplasms

,

large b-cell lymphoma diffuse

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

opioid-related disorders

,

alzheimer disease

,

huntington disease

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

,

,

triple negative breast neoplasms

,

serogroup b neisseria meningitidis

,

,

urologic neoplasms

,

urinary bladder neoplasms

,

urologic diseases

,

urinary bladder diseases

,

,

,

cognitive dysfunction

,

central nervous system neoplasms

,

solitary fibrous tumors

,

neurofibromatosis 1

,

neurofibromatoses

,

hemangioblastoma

,

hemangiopericytoma

,

,

streptococcal infections

,

thyroid neoplasms

,

thyroid diseases

,

,

breast neoplasms

,

sickle cell anemia

,

,

renal insufficiency

,

,

,

rheumatoid arthritis

,

,

bacterial pneumonia

,

juvenile arthritis

,

psoriatic arthritis

,

ankylosing spondylitis

,

carotid artery diseases

,

atherosclerosis

,

ulcerative colitis

,

,

meningococcal meningitis

,

,

thromboembolism

,

,

,

acquired immunodeficiency syndrome

,

immune reconstitution inflammatory syndrome

,

,

alopecia areata

,

,

,

healthy volunteers/patients

,

,

communicable diseases

,

intraabdominal infections

,

smoking cessation

,

neuroendocrine tumors

,

islet cell adenoma

,

psychomotor agitation

,

,

renal cell carcinoma

,

,

gaucher disease

,

tobacco use disorder

,

,

healthy volunteers/patients

,

,

central nervous system neoplasms

,

nephrotic syndrome

,

laryngeal diseases

,

,

chronic hepatitis

,

,

,

esophageal neoplasms

,

postmenopausal osteoporosis

,

,

irritable bowel syndrome

,

pathologic dilatation

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

,

,

choroid plexus neoplasms

,

oligodendroglioma

,

primitive neuroectodermal tumors

,

,

,

neuroepithelial neoplasms

,

hypertrophic pyloric stenosis

,

ganglioneuroblastoma

,

phenylketonurias

,

neuroendocrine tumors

,

b-cell lymphoma marginal zone

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

rectal diseases

,

gastrointestinal diseases

,

intestinal neoplasms

,

digestive system diseases

,

colonic diseases

,

intestinal diseases

,

autism spectrum disorder

,

drug hypersensitivity

,

renal cell carcinoma

,

,

,

squamous cell carcinoma of head and neck

,

b-cell lymphoma

,

head and neck neoplasms

,

squamous cell carcinoma

,

large b-cell lymphoma diffuse

,

pancreatic ductal carcinoma

,

,

,

uveal neoplasms

,

,

mantle-cell lymphoma

,

multiple myeloma

,

myocardial infarction

,

kidney neoplasms

,

hereditary sensory and autonomic neuropathies

,

myelodysplastic syndromes

,

endometrial neoplasms

,

bronchiolitis obliterans syndrome

,

coronary artery disease

,

hypersensitivity

,

philadelphia chromosome

,

lymphoid leukemia

,

,

squamous cell neoplasms

,

waldenstrom macroglobulinemia

,

myeloid leukemia acute

,

castration-resistant prostatic neoplasms

,

hypertrophic cardiomyopathy

,

acute coronary syndrome

,

myocardial ischemia

,

unstable angina

,

margins of excision

,

gouty arthritis

,

gastrointestinal stromal tumors

,

,

,

retinitis pigmentosa

,

,

,

,

,

portal hypertension

,

atopic dermatitis

,

,

,

,

peritoneal neoplasms

,

intestinal obstruction

,

invasive hydatidiform mole

,

central serous chorioretinopathy

,

,

epstein-barr virus infections

,

oropharyngeal neoplasms

,

hodgkin disease

,

type 1 diabetes mellitus

,

,

neurofibrosarcoma

,

ovarian neoplasms

,

fallopian tube neoplasms

,

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

netherton syndrome

,

,

eosinophilic esophagitis

,

,

systemic mastocytosis

,

mast-cell leukemia

,

,

,

female infertility

,

sickle cell anemia

,

streptococcus agalactiae

,

angioid streaks

,

pseudoxanthoma elasticum

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

microscopic polyangiitis

,

diffuse scleroderma

,

immune system diseases

,

t-cell lymphoma

,

malignant mesothelioma

,

lymphatic diseases

,

immunoproliferative disorders

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

,

myeloid leukemia

,

triple negative breast neoplasms

,

,

prostatic neoplasms

,

follicular lymphoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

non-hodgkin lymphoma

,

cardiovascular diseases

,

hypercholesterolemia

,

graft vs host disease

,

,

psoriatic arthritis

,

,

rheumatoid arthritis

,

meningococcal meningitis

,

meningococcal infections

,

neoplasms by site

,

rectal neoplasms

,

osteitis deformans

,

,

degenerative myopia

,

stomach neoplasms

,

,

neoplasms by histologic type

,

inferior wall myocardial infarction

,

,

psychology rejection

,

organ transplantation

,

graft rejection

,

adenocarcinoma of lung

,

,

aplastic anemia

,

,

carcinoid tumor

,

,

chronic hepatitis c

,

lupus nephritis

,

,

colonic neoplasms

,

retinopathy of prematurity

,

polycythemia vera

,

male breast neoplasms

,

,

,

,

lymphoproliferative disorders

,

hematologic neoplasms

,

left ventricular dysfunction

,

st elevation myocardial infarction

,

non-st elevated myocardial infarction

,

,

,

,

infectious skin diseases

,

soft tissue infections

,

,

malignant carcinoid syndrome

,

serotonin syndrome

,

erectile dysfunction

,

peanut hypersensitivity

,

allergic rhinitis seasonal

,

,

,

haemophilus infections

,

,

cerebrotendinous xanthomatosis

,

,

muscular diseases

,

muscular atrophy

,

spinal muscular atrophy

,

x-linked bulbo-spinal atrophy

,

neovascular glaucoma

,

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

chronic obstructive pulmonary disease

,

,

alpha 1-antitrypsin deficiency

,

primary myelofibrosis

,

progressive supranuclear palsy

,

pick disease of the brain

,

,

breast neoplasms

,

,

macular degeneration

,

,

,

,

kidney transplantation

,

vision disorders

,

choroidal neovascularization

,

type 2 diabetes mellitus

,

neoplasm metastasis

,

retinal vein occlusion

,

chronic urticaria

,

diabetes mellitus

,

liver transplantation

,

essential hypertension

,

multiple sclerosis

,

diabetic retinopathy

,

kidney diseases

,

brain neoplasms

,

relapsing-remitting multiple sclerosis

,

metabolic syndrome

,

renal insufficiency

,

,

pancreatic neoplasms

,

,

chronic kidney failure

,

,

retinal diseases

,

systolic heart failure

,

,

insulin resistance

,

,

geographic atrophy

,

parkinson disease

,

diastolic heart failure

,

chronic renal insufficiency

,

,

diabetic nephropathies

,

wet macular degeneration

,

,

,

retinal neovascularization

,

polypoidal choroidal vasculopathy

,

liver cirrhosis

,

,

diabetes complications

,

isolated systolic hypertension

,

systolic murmurs

,

left ventricular hypertrophy

,

,

glucose intolerance

,

,

chronic progressive multiple sclerosis

,

membranous glomerulonephritis

,

,

,

pathologic neovascularization

,

tick-borne encephalitis

,

,

,

,

renal replacement therapy

,

,

prehypertension

,

,

staphylococcal skin infections

,

,

,

neurobehavioral manifestations

,

heart transplantation

,

pituitary acth hypersecretion

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

,

pituitary neoplasms

,

,

sexual infantilism

,

heart-lung transplantation

,

,

coronavirus infections

,

polyomavirus infections

,

retinal detachment

,

atrial fibrillation

,

iga glomerulonephritis

,

focal segmental glomerulosclerosis

,

nephrosclerosis

,

allergic conjunctivitis

,

reperfusion injury

,

delayed graft function

,

food hypersensitivity

,

islet cell adenoma

,

metabolic bone diseases

,

cryopyrin-associated periodic syndromes

,

,

,

,

immunosuppression therapy

,

angina pectoris

,

microvascular angina

,

spinal muscular atrophies of childhood

,

hematopoietic stem cell transplantation

,

secondary prevention

,

glomerulonephritis

,

,

,

,

pulmonary hypertension

,

pulmonary arterial hypertension

,

,

pulmonary edema

,

,

squamous cell carcinoma

,

squamous cell neoplasms

,

prostatic neoplasms

,

peritoneal neoplasms

,

breast neoplasms

,

,

,

ovarian neoplasms

,

acquired immunodeficiency syndrome

,

,

communicable diseases

,

neoplasm metastasis

,

,

,

premature obstetric labor

,

,

ovarian epithelial carcinoma

,

overactive urinary bladder

,

non-small-cell lung carcinoma

,

chronic renal insufficiency

,

kidney diseases

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

,

,

head and neck neoplasms

,

renal cell carcinoma

,

,

urinary tract infections

,

,

non-hodgkin lymphoma

,

fallopian tube neoplasms

,

endometrial neoplasms

,

erectile dysfunction

,

,

muscle spasticity

,

urinary incontinence

,

,

postmenopausal osteoporosis

,

stomach neoplasms

,

gastrointestinal neoplasms

,

acute coronary syndrome

,

,

parkinson disease

,

respiratory tract diseases

,

orthomyxoviridae infections

,

human influenza

,

,

,

brain neoplasms

,

small cell lung carcinoma

,

,

venous thrombosis

,

thrombophlebitis

,

,

,

,

postoperative nausea and vomiting

,

post-traumatic stress disorders

,

traumatic stress disorders

,

,

,

,

triple negative breast neoplasms

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

immunologic deficiency syndromes

,

atherosclerosis

,

,

,

systemic lupus erythematosus

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

osteogenesis imperfecta

,

atopic dermatitis

,

healthy volunteers/patients

,

,

kidney neoplasms

,

multiple myeloma

,

smoldering multiple myeloma

,

urologic neoplasms

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

ureteral neoplasms

,

renal cell carcinoma

,

chronic renal insufficiency

,

,

secondary hyperparathyroidism

,

neoplasm metastasis

,

hyperparathyroidism

,

,

corneal injuries

,

,

intestinal fistula

,

,

,

intraabdominal infections

,

skin transplantation

,

periodontal diseases

,

periodontal pocket

,

periodontal attachment loss

,

urethral stricture

,

abdominal hernia

,

,

fecal incontinence

,

,

corneal perforation

,

,

neoplasm metastasis

,

,

postoperative hemorrhage

,

,

chronic periodontitis

,

rotator cuff injuries

,

,

,

,

,

,

pathologic processes

,

,

pulmonary emphysema

,

esophageal neoplasms

,

,

intracranial hypotension

,

,

foreign-body reaction

,

,

gastrointestinal diseases

,

,

osteoporotic fractures

,

surgical anastomosis

,

femoral neck fractures

,

pleural effusion

,

esophageal stenosis

,

pathologic constriction

,

endoscopic mucosal resection

,

,

cerebrospinal fluid leak

,

wounds and injuries

,

,

surgical blood loss

,

tympanic membrane perforation

,

postoperative complications

,

stress fractures

,

,

cartilage diseases

,

replacement arthroplasty knee

,

,

,

,

cartilage fractures

,

,

,

intervertebral disc degeneration

,

,

,

spinal cord injuries

,

cardiovascular diseases

,

,

,

thyroid neoplasms

,

peripheral vascular diseases

,

,

pancreatic fistula

,

osteochondritis

,

osteochondritis dissecans

,

,

,

catheter ablation

,

,

,

,

,

,

follicular lymphoma

,

,

,

inflammatory bowel diseases

,

segmental mastectomy

,

liver cirrhosis

,

esophageal and gastric varices

,

cardiopulmonary bypass

,

,

vulvar neoplasms

,

,

,

,

,

inguinal hernia

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

postoperative pain

,

,

anastomotic leak

,

breast neoplasms

,

,

stomach neoplasms

,

soft tissue injuries

,

,

,

digestive system fistula

,

,

pancreatic neoplasms

,

,

,

liver transplantation

,

incisional hernia

,

squamous cell carcinoma

,

squamous cell neoplasms

,

,

,

,

,

,

,

,

gingival recession

,

knee osteoarthritis

,

,

,

alveolar bone loss

,

cerebrospinal fluid otorrhea

,

,

,

retinal detachment

,

,

minimally invasive surgical procedures

,

,

surgical staplers

,

conjunctival neoplasms

,

kidney neoplasms

,

pelvic organ prolapse

,

biliary fistula

,

microcirculation

,

,

kidney transplantation

,

,

replacement arthroplasty hip

,

femoracetabular impingement

,

gingival overgrowth

,

gingival hyperplasia

,

gingival hypertrophy

,

gastroesophageal reflux

,

,

,

congenital abnormalities

,

,

limbal stem cell deficiency

,

,

neurogenic urinary bladder

,

intra-articular fractures

,

fracture fixation

,

,

sinus floor augmentation

,

postoperative nausea and vomiting

,

bariatric surgery

,

healthy volunteers/patients

,

oroantral fistula

,

stress urinary incontinence

,

uterine prolapse

,

,

,

tissue preservation

,

paranasal sinus diseases

,

pilonidal sinus

,

pituitary neoplasms

,

tibial meniscus injuries

,

,

peripheral nerve injuries

,

anterior cruciate ligament injuries

,

anterior cruciate ligament reconstruction

,

intracranial hypertension

,

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