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Trade Name	Drug Name	Approved	Patent Expires	Indication
Hyftor	Sirolimus	2022-03-22	2029-2040	Kidney transplantation , Lymphangioleiomyomatosis , Perivascular epithelioid cell neoplasms , Graft rejection

Clinical Trials

Therapeutic Areas:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

triple negative breast neoplasms

,

neoplasm metastasis

,

port-wine stain

,

capillary hemangioma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

t-cell lymphoma peripheral

,

lymphoid leukemia

,

,

,

pancreatic neoplasms

,

,

brain neoplasms

,

,

,

oligodendroglioma

,

tuberous sclerosis

,

,

,

,

head and neck neoplasms

,

multiple myeloma

,

colorectal neoplasms

,

endometrial neoplasms

,

squamous cell neoplasms

,

non-small-cell lung carcinoma

,

,

squamous cell carcinoma

,

nasopharyngeal neoplasms

,

multiple hamartoma syndrome

,

,

,

,

kasabach-merritt syndrome

,

hemangioendothelioma

,

hepatocellular carcinoma

,

liver neoplasms

,

chronic kidney failure

,

pulmonary vein stenosis

,

pathologic constriction

,

,

,

thyroid neoplasms

,

thyroid diseases

,

central nervous system neoplasms

,

nervous system neoplasms

,

systemic lupus erythematosus

,

,

renal cell carcinoma

,

,

breast neoplasms

,

,

kidney neoplasms

,

,

urogenital neoplasms

,

renal insufficiency

,

carotid artery diseases

,

atherosclerosis

,

brain stem infarctions

,

sturge-weber syndrome

,

klippel-trenaunay-weber syndrome

,

cognitive dysfunction

,

unilateral breast neoplasms

,

kidney transplantation

,

,

non-hodgkin lymphoma

,

mantle-cell lymphoma

,

graft rejection

,

,

gastrointestinal stromal tumors

,

neuroendocrine tumors

,

islet cell adenoma

,

,

atrial fibrillation

,

,

,

,

myeloid leukemia acute

,

hematologic neoplasms

,

myeloid leukemia

,

neoplasms by histologic type

healthy volunteers/patients

,

,

bacterial pneumonia

,

duchenne muscular dystrophy

,

muscular dystrophies

,

,

communicable diseases

,

myeloid leukemia

,

healthy volunteers/patients

,

ulcerative colitis

,

,

,

rheumatoid arthritis

,

myeloid leukemia acute

,

atopic dermatitis

,

hidradenitis suppurativa

,

,

,

,

pathologic constriction

,

inflammatory bowel diseases

,

intestinal diseases

pharmacokinetics

,

inflammatory breast neoplasms

,

,

renal cell carcinoma

,

communicable diseases

,

pneumococcal infections

,

immune system diseases

,

triple negative breast neoplasms

,

,

,

,

,

,

,

oligodendroglioma

,

small cell lung carcinoma

,

neoplasm metastasis

,

stomach neoplasms

,

esophageal neoplasms

,

hodgkin disease

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

bronchiolitis obliterans syndrome

,

,

plasma cell neoplasms

,

squamous cell carcinoma of head and neck

,

ovarian epithelial carcinoma

,

human influenza

,

fallopian tube neoplasms

,

biliary tract neoplasms

,

prolymphocytic leukemia

,

pancreatic neoplasms

,

,

hepatocellular carcinoma

,

liver neoplasms

,

head and neck neoplasms

,

pancreatic ductal carcinoma

,

induction chemotherapy

,

,

adenocarcinoma of lung

,

gestational diabetes

,

pregnancy in diabetics

,

coronary disease

,

large b-cell lymphoma diffuse

,

brain neoplasms

,

mucopolysaccharidoses

,

mucopolysaccharidosis i

,

follicular lymphoma

,

hematopoietic stem cell transplantation

,

peripheral arterial disease

,

atherosclerosis

,

intermittent claudication

,

peripheral vascular diseases

,

,

,

,

,

meningococcal meningitis

,

haemophilus infections

,

cutaneous malignant melanoma

,

esophageal squamous cell carcinoma

,

urinary bladder neoplasms

,

,

rectal neoplasms

,

congenital abnormalities

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

erythroblastic leukemia acute

,

hypersensitivity

,

peanut hypersensitivity

,

squamous cell carcinoma

,

squamous cell neoplasms

,

prolymphocytic leukemia t-cell

,

allergic rhinitis

,

,

acquired immunodeficiency syndrome

,

sezary syndrome

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

pulmonary alveolar proteinosis

,

,

t-cell lymphoma peripheral

,

laryngeal neoplasms

,

,

alpha 1-antitrypsin deficiency

,

breast neoplasms

,

colorectal neoplasms

,

multiple myeloma

,

non-small-cell lung carcinoma

,

,

myeloid leukemia acute

,

b-cell chronic lymphocytic leukemia

,

,

,

,

myelodysplastic syndromes

,

,

ovarian neoplasms

,

,

,

graft vs host disease

,

meningococcal infections

,

,

healthy volunteers/patients

,

,

hematologic neoplasms

,

,

pneumococcal pneumonia

,

,

haemophilus influenzae type b

,

,

,

myeloid leukemia

,

,

venous thrombosis

,

rheumatoid arthritis

,

,

bcr-abl positive chronic myelogenous leukemia

,

aplastic anemia

,

thrombotic thrombocytopenic purpura

,

,

neuroendocrine tumors

,

carcinoid tumor

,

,

paraneoplastic syndromes

,

islet cell carcinoma

,

islet cell adenoma

,

,

,

somatostatinoma

,

pulmonary embolism

,

,

,

st elevation myocardial infarction

,

glucose intolerance

,

hematologic diseases

,

inborn genetic diseases

,

blood coagulation disorders

,

x-linked genetic diseases

,

hemorrhagic disorders

,

inherited blood coagulation disorders

,

coagulation protein disorders

,

fetal growth retardation

,

thromboembolism

,

noonan syndrome

,

bacterial meningitis

,

,

myeloproliferative disorders

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

,

type 2 diabetes mellitus

,

type 1 diabetes mellitus

,

glycogen storage disease type ii

,

,

diabetes mellitus

,

prostatic neoplasms

,

non-hodgkin lymphoma

,

multiple sclerosis

,

,

glycogen storage disease type iii

,

relapsing-remitting multiple sclerosis

,

,

,

graft rejection

,

chronic kidney failure

,

insulin resistance

,

renal insufficiency

,

kidney transplantation

,

autologous transplantation

,

acute coronary syndrome

,

myocardial infarction

,

,

,

liver transplantation

,

psychology rejection

,

atrial fibrillation

,

,

,

,

,

,

,

,

,

inferior wall myocardial infarction

,

kidney diseases

,

coronary artery disease

,

immunosuppression therapy

,

,

,

glycogen storage disease

,

,

lymphoproliferative disorders

,

paraproteinemias

,

heart transplantation

,

reperfusion injury

colorectal neoplasms

,

,

rectal neoplasms

,

squamous cell carcinoma of head and neck

,

chronic obstructive pulmonary disease

,

,

multiple myeloma

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

breast neoplasms

,

,

non-small-cell lung carcinoma

,

vision disorders

,

bcr-abl positive chronic myelogenous leukemia

,

,

neoplasm metastasis

,

,

,

,

myeloid leukemia

,

spondylarthritis

,

,

,

,

psoriatic arthritis

,

ankylosing spondylitis

,

retinal vein occlusion

,

,

chronic urticaria

,

,

cystic fibrosis

,

choroidal neovascularization

,

osteitis deformans

,

renal cell carcinoma

,

philadelphia chromosome

,

ovarian neoplasms

,

pituitary acth hypersecretion

,

,

,

myelodysplastic syndromes

,

thrombocytopenia

,

,

diabetic retinopathy

,

retinal neovascularization

,

macular degeneration

,

,

hematologic diseases

,

sickle cell anemia

,

sickle cell trait

,

vaso-occlusive crises

,

,

,

,

,

neuroendocrine tumors

,

,

,

gastrointestinal stromal tumors

,

triple negative breast neoplasms

,

myeloid leukemia acute

,

acth-secreting pituitary adenoma

,

,

pseudomonas aeruginosa

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

respiratory aspiration

,

prostatic neoplasms

,

myelomonocytic leukemia chronic

,

,

wet macular degeneration

,

pathologic neovascularization

,

adenocarcinoma of lung

,

brain neoplasms

,

,

hepatocellular carcinoma

,

stomach neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

carcinoid tumor

,

malignant carcinoid syndrome

,

serotonin syndrome

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

homozygous familial hypercholesterolemia

,

,

lupus nephritis

,

,

axial spondyloarthritis

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

allergic rhinitis seasonal

,

graft vs host disease

,

primary myelofibrosis

,

,

inclusion body myositis

,

juvenile arthritis

,

hereditary autoinflammatory diseases

,

,

familial mediterranean fever

,

diabetes mellitus

,

rheumatoid arthritis

,

hereditary sensory and autonomic neuropathies

,

,

hyperlipoproteinemia type i

,

hyperpituitarism

,

degenerative myopia

,

,

non-hodgkin lymphoma

,

,

pulmonary infarction

,

hodgkin disease

,

behcet syndrome

,

,

,

,

giant cell arteritis

,

,

thyroid neoplasms

,

food hypersensitivity

,

peanut hypersensitivity

,

polymyalgia rheumatica

,

male breast neoplasms

,

,

follicular lymphoma

,

polycythemia vera

,

,

,

myeloid leukemia chronic-phase

,

,

iga glomerulonephritis

,

,

left ventricular hypertrophy

,

pathologic dilatation

,

,

essential hypertension

,

systolic murmurs

,

mantle-cell lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

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