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Trade Name	Drug Name	Approved	Patent Expires	Indication
Hyftor	Sirolimus	2022-03-22	2029-2040	Kidney transplantation , Lymphangioleiomyomatosis , Perivascular epithelioid cell neoplasms , Graft rejection

Clinical Trials

Therapeutic Areas:

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Classification:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

triple negative breast neoplasms

,

neoplasm metastasis

,

port-wine stain

,

capillary hemangioma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

t-cell lymphoma peripheral

,

lymphoid leukemia

,

,

,

pancreatic neoplasms

,

,

brain neoplasms

,

,

,

oligodendroglioma

,

tuberous sclerosis

,

,

,

,

,

head and neck neoplasms

,

multiple myeloma

,

colorectal neoplasms

,

endometrial neoplasms

,

squamous cell neoplasms

,

non-small-cell lung carcinoma

,

,

squamous cell carcinoma

,

nasopharyngeal neoplasms

,

multiple hamartoma syndrome

,

,

,

,

kasabach-merritt syndrome

,

hemangioendothelioma

,

hepatocellular carcinoma

,

liver neoplasms

,

chronic kidney failure

,

pulmonary vein stenosis

,

pathologic constriction

,

,

,

thyroid neoplasms

,

thyroid diseases

,

central nervous system neoplasms

,

nervous system neoplasms

,

systemic lupus erythematosus

,

,

renal cell carcinoma

,

,

breast neoplasms

,

kidney neoplasms

,

,

urogenital neoplasms

,

renal insufficiency

,

carotid artery diseases

,

atherosclerosis

,

brain stem infarctions

,

sturge-weber syndrome

,

klippel-trenaunay-weber syndrome

,

cognitive dysfunction

,

kidney transplantation

,

,

non-hodgkin lymphoma

,

mantle-cell lymphoma

,

graft rejection

,

,

gastrointestinal stromal tumors

,

neuroendocrine tumors

,

islet cell adenoma

,

,

atrial fibrillation

,

multiple myeloma

,

,

brain neoplasms

,

,

,

,

,

central nervous system neoplasms

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

follicular lymphoma

,

,

,

,

,

choroid plexus neoplasms

,

oligodendroglioma

,

primitive neuroectodermal tumors

,

,

,

neuroepithelial neoplasms

,

hypertrophic pyloric stenosis

,

ganglioneuroblastoma

,

phenylketonurias

,

breast neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

lymphoid leukemia

,

,

prostatic neoplasms

,

mantle-cell lymphoma

,

hodgkin disease

,

pancreatic neoplasms

,

triple negative breast neoplasms

,

endometrial neoplasms

,

,

non-hodgkin lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

myeloid leukemia acute

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

myeloid leukemia chronic-phase

healthy volunteers/patients

,

,

bacterial pneumonia

,

duchenne muscular dystrophy

,

muscular dystrophies

,

,

communicable diseases

beta-thalassemia

,

,

,

newborn respiratory distress syndrome

,

,

parkinson disease

,

deficiency diseases

,

chronic renal insufficiency

,

kidney diseases

,

,

inflammatory bowel diseases

,

intestinal diseases

,

iron deficiencies

,

iron-deficiency anemia

,

,

left ventricular dysfunction

,

,

parkinson disease

,

,

,

large-cell lymphoma anaplastic

,

,

,

neoplasms by histologic type

,

neoplasms by site

,

plasma cell leukemia

,

optic nerve glioma

,

primitive neuroectodermal tumors peripheral

,

immunoblastic lymphadenopathy

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

basal cell carcinoma

,

basal cell neoplasms

,

human influenza

,

brain stem neoplasms

,

cerebrotendinous xanthomatosis

,

stem cell transplantation

,

adenocarcinoma of lung

,

,

precancerous conditions

,

smoldering multiple myeloma

,

mycobacterium avium-intracellulare infection

,

mycobacterium infections

,

,

carcinoid tumor

,

healthy volunteers/patients

,

,

respiratory syncytial virus infections

,

cystic fibrosis

,

,

phenylketonurias

,

myasthenia gravis

,

myelomonocytic leukemia juvenile

,

pancreatic ductal carcinoma

,

conjunctival neoplasms

,

clear cell sarcoma

,

gastrointestinal stromal tumors

,

salivary gland neoplasms

,

testicular neoplasms

,

medullary carcinoma

,

thrombocytopenia

,

paroxysmal hemoglobinuria

,

aids-related complex

,

,

parkinsonian disorders

,

pharmacokinetics

,

,

ovarian neoplasms

,

colorectal neoplasms

,

,

b-cell chronic lymphocytic leukemia

,

myeloid leukemia

,

non-small-cell lung carcinoma

,

,

,

myeloproliferative disorders

,

kidney neoplasms

,

mantle-cell lymphoma

,

fallopian tube neoplasms

,

central nervous system neoplasms

,

hodgkin disease

,

ovarian epithelial carcinoma

,

,

male breast neoplasms

,

lymphoid leukemia

,

burkitt lymphoma

,

liver neoplasms

,

,

stomach neoplasms

,

medulloblastoma

,

large-cell lymphoma immunoblastic

,

hepatocellular carcinoma

,

myelodysplastic-myeloproliferative diseases

,

oligodendroglioma

,

b-cell lymphoma

,

,

colonic neoplasms

,

,

b-cell lymphoma marginal zone

,

nervous system neoplasms

,

respiratory distress syndrome

,

malignant mesothelioma

,

,

myeloid leukemia accelerated phase

,

myelomonocytic leukemia chronic

,

,

,

rectal neoplasms

,

,

diffuse intrinsic pontine glioma

,

hematologic neoplasms

,

squamous cell carcinoma

,

small cell lung carcinoma

,

rheumatoid arthritis

,

,

t-cell lymphoma cutaneous

,

,

,

primitive neuroectodermal tumors

,

castration-resistant prostatic neoplasms

,

alzheimer disease

,

endometrial neoplasms

,

drug-related side effects and adverse reactions

,

peripheral arterial disease

,

ductal carcinoma breast

,

uterine cervical neoplasms

,

esophageal neoplasms

,

intraductal carcinoma noninfiltrating

,

squamous cell carcinoma of head and neck

,

refractory anemia

,

alveolar soft part sarcoma

,

inflammatory breast neoplasms

,

nasopharyngeal carcinoma

,

aplastic anemia

,

,

t-cell lymphoma peripheral

,

,

intestinal neoplasms

,

sezary syndrome

,

waldenstrom macroglobulinemia

,

mycosis fungoides

,

glandular and epithelial neoplasms

,

endometrioid carcinoma

,

merkel cell carcinoma

,

squamous cell neoplasms

,

subependymal glioma

,

germ cell and embryonal neoplasms

,

peritoneal neoplasms

,

neuroendocrine tumors

,

islet cell adenoma

,

severe acute respiratory syndrome

,

acute lung injury

,

newborn respiratory distress syndrome

,

respiratory aspiration

,

transitional cell carcinoma

,

cholangiocarcinoma

,

gallbladder neoplasms

,

residual neoplasm

,

nasopharyngeal neoplasms

,

gastrointestinal neoplasms

,

immunologic deficiency syndromes

,

t-cell lymphoma

,

immunoglobulin light-chain amyloidosis

,

,

pulmonary hypertension

,

systemic scleroderma

,

interstitial lung diseases

,

diffuse scleroderma

,

lymphoproliferative disorders

,

extranodal nk-t-cell lymphoma

,

primary myelofibrosis

,

prolymphocytic leukemia

,

interdigitating dendritic cell sarcoma

,

,

thymus neoplasms

,

biliary tract neoplasms

,

,

mucinous cystadenocarcinoma

,

serous cystadenocarcinoma

,

cystadenocarcinoma

,

,

animal mammary neoplasms

,

,

basophilic leukemia acute

,

eosinophilic leukemia acute

,

,

neuroectodermal tumors

,

cognitive dysfunction

,

,

severe acute respiratory syndrome-related coronavirus

,

,

unilateral breast neoplasms

,

kidney diseases

,

kidney transplantation

,

urogenital neoplasms

,

prostatic diseases

,

male genital neoplasms

,

critical illness

,

immunosuppression therapy

,

,

trophoblastic neoplasms

,

,

,

vascular diseases

,

atherosclerosis

,

intermittent claudication

,

pneumococcal pneumonia

,

,

bile duct neoplasms

,

laryngeal neoplasms

,

,

urologic neoplasms

,

,

,

,

soft tissue neoplasms

,

,

,

breast neoplasms

,

prostatic neoplasms

,

multiple myeloma

,

myelodysplastic syndromes

,

non-hodgkin lymphoma

,

plasma cell neoplasms

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

follicular lymphoma

,

pancreatic neoplasms

,

,

pulmonary alveolar proteinosis

,

neoplasm metastasis

,

large b-cell lymphoma diffuse

,

,

brain neoplasms

,

renal cell carcinoma

,

cutaneous malignant melanoma

,

,

myeloid leukemia chronic-phase

,

,

acquired immunodeficiency syndrome

,

uveal neoplasms

,

triple negative breast neoplasms

,

rhabdomyosarcoma

,

,

,

,

congenital abnormalities

,

head and neck neoplasms

,

,

,

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

erythroblastic leukemia acute

,

ganglioneuroblastoma

,

urinary bladder neoplasms

,

graft vs host disease

,

refractory anemia with excess of blasts

,

communicable diseases

,

,

hematologic diseases

,

,

radiation effects

,

pathologic complete response

,

alveolar rhabdomyosarcoma

,

embryonal rhabdomyosarcoma

,

cytomegalovirus retinitis

,

,

cutaneous leishmaniasis

,

,

coronavirus infections

,

,

,

invasive fungal infections

,

,

tongue neoplasms

,

,

,

,

,

myeloid leukemia acute

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

,

chronic hepatitis b

,

,

multiple organ failure

,

,

,

,

respiratory insufficiency

,

wounds and injuries

,

liver cirrhosis

,

,

,

graft rejection

,

,

periodontal diseases

,

,

peripheral vascular diseases

,

surgical blood loss

,

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