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Trade Name	Drug Name	Approved	Patent Expires	Indication
Hyftor	Sirolimus	2022-03-22	2029-2040	Kidney transplantation , Lymphangioleiomyomatosis , Perivascular epithelioid cell neoplasms , Graft rejection

Clinical Trials

Therapeutic Areas:

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Classification:

All

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Status:

All

Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

triple negative breast neoplasms

,

neoplasm metastasis

,

port-wine stain

,

capillary hemangioma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

t-cell lymphoma peripheral

,

lymphoid leukemia

,

,

,

pancreatic neoplasms

,

,

brain neoplasms

,

,

,

oligodendroglioma

,

tuberous sclerosis

,

,

,

,

head and neck neoplasms

,

multiple myeloma

,

colorectal neoplasms

,

endometrial neoplasms

,

squamous cell neoplasms

,

non-small-cell lung carcinoma

,

,

squamous cell carcinoma

,

nasopharyngeal neoplasms

,

multiple hamartoma syndrome

,

,

,

,

kasabach-merritt syndrome

,

hemangioendothelioma

,

hepatocellular carcinoma

,

liver neoplasms

,

chronic kidney failure

,

pulmonary vein stenosis

,

pathologic constriction

,

,

,

thyroid neoplasms

,

thyroid diseases

,

central nervous system neoplasms

,

nervous system neoplasms

,

systemic lupus erythematosus

,

,

renal cell carcinoma

,

,

breast neoplasms

,

,

kidney neoplasms

,

,

urogenital neoplasms

,

renal insufficiency

,

carotid artery diseases

,

atherosclerosis

,

brain stem infarctions

,

sturge-weber syndrome

,

klippel-trenaunay-weber syndrome

,

cognitive dysfunction

,

unilateral breast neoplasms

,

kidney transplantation

,

,

non-hodgkin lymphoma

,

mantle-cell lymphoma

,

graft rejection

,

,

gastrointestinal stromal tumors

,

neuroendocrine tumors

,

islet cell adenoma

,

,

atrial fibrillation

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

mantle-cell lymphoma

,

non-hodgkin lymphoma

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

,

myeloid leukemia acute

,

myeloid leukemia

hematologic neoplasms

,

fallopian tube neoplasms

,

ovarian epithelial carcinoma

,

parkinson disease

,

myeloid leukemia acute

,

,

myeloid leukemia

,

myelodysplastic syndromes

,

hodgkin disease

,

breast neoplasms

,

bcr-abl positive chronic myelogenous leukemia

,

type 1 diabetes mellitus

,

hematopoietic stem cell transplantation

,

plasma cell neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

stomach neoplasms

,

,

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

follicular lymphoma

,

graft vs host disease

,

stem cell transplantation

,

diabetes mellitus

,

alzheimer disease

,

cognitive dysfunction

,

pulmonary alveolar proteinosis

,

multiple myeloma

,

,

,

,

aplastic anemia

,

,

non-hodgkin lymphoma

,

prostatic neoplasms

,

,

autologous transplantation

,

,

lymphoproliferative disorders

,

paraproteinemias

duchenne muscular dystrophy

,

muscular dystrophies

healthy volunteers/patients

,

renal insufficiency

,

chronic kidney failure

,

myeloid leukemia acute

,

,

myelodysplastic syndromes

,

non-hodgkin lymphoma

,

,

acquired immunodeficiency syndrome

,

immunologic deficiency syndromes

,

,

,

respiratory syncytial virus infections

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

respiratory syncytial viruses

,

venous thrombosis

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

smoldering multiple myeloma

,

,

neoplasm metastasis

,

chronic hepatitis c

,

breast neoplasms

,

,

peripheral nervous system diseases

,

hematologic neoplasms

,

colorectal neoplasms

,

,

graft vs host disease

,

bronchiolitis obliterans syndrome

,

multiple myeloma

,

,

non-small-cell lung carcinoma

,

,

plasma cell neoplasms

,

,

,

communicable diseases

,

,

,

,

,

ovarian neoplasms

,

juvenile arthritis

,

thromboembolism

,

respiratory tract infections

,

,

major depressive disorder

,

depressive disorder

,

treatment-resistant depressive disorder

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

ovarian epithelial carcinoma

,

inflammatory bowel diseases

,

b-cell chronic lymphocytic leukemia

,

,

respiratory insufficiency

,

rheumatic diseases

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

psychotic disorders

,

bipolar disorder

,

psychotic affective disorders

,

,

mental disorders

,

human influenza

,

venous thromboembolism

,

kidney transplantation

,

,

type 2 diabetes mellitus

,

,

prostatic neoplasms

,

urogenital neoplasms

,

male genital diseases

,

male genital neoplasms

,

genital diseases

,

,

,

attention deficit disorder with hyperactivity

,

cognitive dysfunction

,

thyroid neoplasms

,

papillary thyroid cancer

,

thyroid diseases

,

,

,

retinal diseases

,

,

ankle fractures

,

fibula fractures

head and neck neoplasms

,

,

atherosclerosis

,

intracranial arteriosclerosis

,

fallopian tube neoplasms

,

,

squamous cell carcinoma of head and neck

,

,

prostatic neoplasms

,

renal cell carcinoma

,

triple negative breast neoplasms

,

basal cell carcinoma

,

neoplasm metastasis

,

basal cell neoplasms

,

ovarian epithelial carcinoma

,

colorectal neoplasms

,

pancreatic neoplasms

,

hypersensitivity

,

peanut hypersensitivity

,

allergic rhinitis

,

,

chronic disease

,

healthy volunteers/patients

,

squamous cell carcinoma

,

merkel cell carcinoma

,

,

adenocarcinoma of lung

,

food hypersensitivity

,

milk hypersensitivity

,

smoldering multiple myeloma

,

monoclonal gammopathy of undetermined significance

,

,

,

hearing disorders

,

sensorineural hearing loss

,

bronchogenic carcinoma

,

bronchial neoplasms

,

paroxysmal hemoglobinuria

,

colonic neoplasms

,

malignant mesothelioma

,

,

chronic renal insufficiency

,

diabetic nephropathies

,

,

rectal neoplasms

,

non-alcoholic fatty liver disease

,

non-small-cell lung carcinoma

,

ovarian neoplasms

,

,

,

retinal diseases

,

follicular lymphoma

,

diabetic retinopathy

,

,

b-cell lymphoma

,

rheumatoid arthritis

,

,

,

type 2 diabetes mellitus

,

multiple myeloma

,

heterotopic ossification

,

myositis ossificans

,

vitreous hemorrhage

,

hodgkin disease

,

large b-cell lymphoma diffuse

,

vision disorders

,

,

,

hyperlipidemias

,

diabetes mellitus

,

b-cell lymphoma marginal zone

,

non-hodgkin lymphoma

,

macular degeneration

,

protein-losing enteropathies

,

,

,

,

,

,

mantle-cell lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

,

,

corneal injuries

,

,

intestinal fistula

,

,

,

intraabdominal infections

,

skin transplantation

,

periodontal diseases

,

periodontal pocket

,

periodontal attachment loss

,

urethral stricture

,

abdominal hernia

,

,

fecal incontinence

,

,

corneal perforation

,

,

neoplasm metastasis

,

,

postoperative hemorrhage

,

,

chronic periodontitis

,

rotator cuff injuries

,

,

,

,

,

,

pathologic processes

,

,

pulmonary emphysema

,

esophageal neoplasms

,

,

intracranial hypotension

,

,

foreign-body reaction

,

,

gastrointestinal diseases

,

,

osteoporotic fractures

,

surgical anastomosis

,

femoral neck fractures

,

pleural effusion

,

esophageal stenosis

,

pathologic constriction

,

endoscopic mucosal resection

,

,

cerebrospinal fluid leak

,

wounds and injuries

,

,

surgical blood loss

,

tympanic membrane perforation

,

postoperative complications

,

stress fractures

,

,

cartilage diseases

,

replacement arthroplasty knee

,

,

,

,

cartilage fractures

,

,

,

intervertebral disc degeneration

,

,

,

spinal cord injuries

,

cardiovascular diseases

,

,

,

thyroid neoplasms

,

peripheral vascular diseases

,

,

pancreatic fistula

,

osteochondritis

,

osteochondritis dissecans

,

,

,

catheter ablation

,

,

,

,

,

,

follicular lymphoma

,

,

,

inflammatory bowel diseases

,

segmental mastectomy

,

liver cirrhosis

,

esophageal and gastric varices

,

cardiopulmonary bypass

,

,

vulvar neoplasms

,

,

,

,

,

inguinal hernia

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

postoperative pain

,

,

anastomotic leak

,

breast neoplasms

,

,

stomach neoplasms

,

soft tissue injuries

,

,

,

digestive system fistula

,

,

pancreatic neoplasms

,

,

,

liver transplantation

,

incisional hernia

,

squamous cell carcinoma

,

squamous cell neoplasms

,

,

,

,

,

,

,

,

gingival recession

,

knee osteoarthritis

,

,

,

alveolar bone loss

,

cerebrospinal fluid otorrhea

,

,

,

retinal detachment

,

,

minimally invasive surgical procedures

,

,

surgical staplers

,

conjunctival neoplasms

,

kidney neoplasms

,

pelvic organ prolapse

,

biliary fistula

,

microcirculation

,

,

kidney transplantation

,

,

replacement arthroplasty hip

,

femoracetabular impingement

,

gingival overgrowth

,

gingival hyperplasia

,

gingival hypertrophy

,

gastroesophageal reflux

,

,

,

congenital abnormalities

,

,

limbal stem cell deficiency

,

,

neurogenic urinary bladder

,

intra-articular fractures

,

fracture fixation

,

,

sinus floor augmentation

,

postoperative nausea and vomiting

,

bariatric surgery

,

healthy volunteers/patients

,

oroantral fistula

,

stress urinary incontinence

,

uterine prolapse

,

,

,

tissue preservation

,

paranasal sinus diseases

,

pilonidal sinus

,

pituitary neoplasms

,

tibial meniscus injuries

,

,

peripheral nerve injuries

,

anterior cruciate ligament injuries

,

anterior cruciate ligament reconstruction

,

intracranial hypertension

,

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