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Trade Name	Drug Name	Approved	Patent Expires	Indication
Hyftor	Sirolimus	2022-03-22	2029-2040	Kidney transplantation , Lymphangioleiomyomatosis , Perivascular epithelioid cell neoplasms , Graft rejection

Clinical Trials

Therapeutic Areas:

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Classification:

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Status:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

triple negative breast neoplasms

,

neoplasm metastasis

,

port-wine stain

,

capillary hemangioma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

t-cell lymphoma peripheral

,

lymphoid leukemia

,

,

,

pancreatic neoplasms

,

,

brain neoplasms

,

,

,

oligodendroglioma

,

tuberous sclerosis

,

,

,

,

head and neck neoplasms

,

multiple myeloma

,

colorectal neoplasms

,

endometrial neoplasms

,

squamous cell neoplasms

,

non-small-cell lung carcinoma

,

,

squamous cell carcinoma

,

nasopharyngeal neoplasms

,

multiple hamartoma syndrome

,

,

,

,

kasabach-merritt syndrome

,

hemangioendothelioma

,

hepatocellular carcinoma

,

liver neoplasms

,

chronic kidney failure

,

pulmonary vein stenosis

,

pathologic constriction

,

,

,

thyroid neoplasms

,

thyroid diseases

,

central nervous system neoplasms

,

nervous system neoplasms

,

systemic lupus erythematosus

,

,

renal cell carcinoma

,

,

breast neoplasms

,

,

kidney neoplasms

,

,

urogenital neoplasms

,

renal insufficiency

,

carotid artery diseases

,

atherosclerosis

,

brain stem infarctions

,

sturge-weber syndrome

,

klippel-trenaunay-weber syndrome

,

cognitive dysfunction

,

unilateral breast neoplasms

,

kidney transplantation

,

,

non-hodgkin lymphoma

,

mantle-cell lymphoma

,

graft rejection

,

,

gastrointestinal stromal tumors

,

neuroendocrine tumors

,

islet cell adenoma

,

,

atrial fibrillation

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

mantle-cell lymphoma

,

non-hodgkin lymphoma

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

,

myeloid leukemia acute

,

myeloid leukemia

multiple myeloma

,

,

brain neoplasms

,

,

,

,

,

central nervous system neoplasms

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

follicular lymphoma

,

,

,

,

,

choroid plexus neoplasms

,

oligodendroglioma

,

primitive neuroectodermal tumors

,

,

,

neuroepithelial neoplasms

,

hypertrophic pyloric stenosis

,

ganglioneuroblastoma

,

phenylketonurias

,

breast neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

lymphoid leukemia

,

,

prostatic neoplasms

,

mantle-cell lymphoma

,

hodgkin disease

,

pancreatic neoplasms

,

triple negative breast neoplasms

,

endometrial neoplasms

,

,

non-hodgkin lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

myeloid leukemia acute

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

myeloid leukemia chronic-phase

healthy volunteers/patients

,

,

bacterial pneumonia

,

duchenne muscular dystrophy

,

muscular dystrophies

,

,

communicable diseases

,

,

myeloid leukemia acute

,

deficiency diseases

,

paraproteinemias

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

breast neoplasms

,

immune system diseases

,

hematologic neoplasms

,

type 2 diabetes mellitus

,

,

metabolic diseases

,

,

glycogen storage disease

,

,

immunoglobulin g4-related disease

,

,

myeloid leukemia

,

,

falciparum malaria

,

,

,

,

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

,

renal insufficiency

,

hematologic diseases

,

blood protein disorders

,

neoplasms by histologic type

,

prostatic neoplasms

,

circulating neoplastic cells

,

x-linked bulbo-spinal atrophy

,

heart transplantation

,

non-small-cell lung carcinoma

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

esophageal neoplasms

,

,

neoplasm metastasis

,

aplastic anemia

,

multiple myeloma

,

hypercholesterolemia

,

meningococcal infections

,

plasma cell neoplasms

,

hemolytic anemia autoimmune

,

,

meningococcal meningitis

,

stomach neoplasms

,

,

kidney diseases

,

gaucher disease

,

,

chronic renal insufficiency

,

hyperphosphatemia

,

multiple sclerosis

,

,

homozygous familial hypercholesterolemia

,

hyperlipoproteinemia type ii

,

,

,

healthy volunteers/patients

,

,

glycogen storage disease type ii

,

atopic dermatitis

,

diabetes mellitus

,

insulin resistance

,

,

glycogen storage disease type iii

,

,

non-hodgkin lymphoma

,

,

postmenopausal osteoporosis

,

,

lymphoproliferative disorders

uveal neoplasms

,

,

,

primary myelofibrosis

,

healthy volunteers/patients

,

uterine cervical neoplasms

,

rectal neoplasms

,

cholangiocarcinoma

,

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

colorectal neoplasms

,

stomach neoplasms

,

,

,

ovarian neoplasms

,

triple negative breast neoplasms

,

large b-cell lymphoma diffuse

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

non-hodgkin lymphoma

,

ulcerative colitis

,

b-cell chronic lymphocytic leukemia

,

small cell lung carcinoma

,

,

neoplasm metastasis

,

b-cell lymphoma

,

,

,

lupus nephritis

,

ductal carcinoma breast

,

macular degeneration

,

,

renal cell carcinoma

,

transitional cell carcinoma

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

urinary bladder neoplasms

,

colonic neoplasms

,

,

head and neck neoplasms

,

,

,

mucinous adenocarcinoma

,

inflammatory breast neoplasms

,

paroxysmal hemoglobinuria

,

pancreatic neoplasms

,

,

,

,

neoplasms by site

,

breast diseases

,

urologic neoplasms

,

prostatic neoplasms

,

,

follicular lymphoma

,

lymphoid leukemia

,

systemic scleroderma

,

diffuse scleroderma

,

retinal vein occlusion

,

,

,

atypical hemolytic uremic syndrome

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

geographic atrophy

,

,

systemic lupus erythematosus

,

nephrotic syndrome

,

ovarian epithelial carcinoma

,

brain neoplasms

,

esophageal squamous cell carcinoma

,

esophageal neoplasms

,

castration-resistant prostatic neoplasms

,

retinal diseases

,

diabetic retinopathy

,

vision disorders

,

,

,

thyroid neoplasms

,

neuroendocrine carcinoma

,

papillary thyroid cancer

,

thyroid diseases

,

disease progression

,

,

endometrioid carcinoma

,

giant cell arteritis

,

type 2 diabetes mellitus

,

diabetes mellitus

,

membranous glomerulonephritis

,

multiple sclerosis

,

chronic progressive multiple sclerosis

,

ankylosing spondylitis

,

spondylarthritis

,

,

myeloid leukemia acute

,

myeloid leukemia

,

alzheimer disease

,

coronary disease

,

acute coronary syndrome

,

coronary artery disease

,

myocardial ischemia

,

,

relapsing-remitting multiple sclerosis

,

guillain-barre syndrome

,

autoimmune diseases of the nervous system

,

bcr-abl positive chronic myelogenous leukemia

,

circulating neoplastic cells

,

disability evaluation

,

cognition disorders

,

cytomegalovirus infections

,

,

,

hemolytic anemia autoimmune

,

,

focal segmental glomerulosclerosis

,

lipoid nephrosis

,

endometrial neoplasms

,

,

graft rejection

,

retinal neovascularization

,

human influenza

,

type 3 von willebrand disease

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

,

adenocarcinoma of lung

,

,

postmenopausal osteoporosis

,

mantle-cell lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

,

,

corneal injuries

,

,

intestinal fistula

,

,

,

intraabdominal infections

,

skin transplantation

,

periodontal diseases

,

periodontal pocket

,

periodontal attachment loss

,

urethral stricture

,

abdominal hernia

,

,

fecal incontinence

,

,

corneal perforation

,

,

neoplasm metastasis

,

,

postoperative hemorrhage

,

,

chronic periodontitis

,

rotator cuff injuries

,

,

,

,

,

,

pathologic processes

,

,

pulmonary emphysema

,

esophageal neoplasms

,

,

intracranial hypotension

,

,

foreign-body reaction

,

,

gastrointestinal diseases

,

,

osteoporotic fractures

,

surgical anastomosis

,

femoral neck fractures

,

pleural effusion

,

esophageal stenosis

,

pathologic constriction

,

endoscopic mucosal resection

,

,

cerebrospinal fluid leak

,

wounds and injuries

,

,

surgical blood loss

,

tympanic membrane perforation

,

postoperative complications

,

stress fractures

,

,

cartilage diseases

,

replacement arthroplasty knee

,

,

,

,

cartilage fractures

,

,

,

intervertebral disc degeneration

,

,

,

spinal cord injuries

,

cardiovascular diseases

,

,

,

thyroid neoplasms

,

peripheral vascular diseases

,

,

pancreatic fistula

,

osteochondritis

,

osteochondritis dissecans

,

,

,

catheter ablation

,

,

,

,

,

,

follicular lymphoma

,

,

,

inflammatory bowel diseases

,

segmental mastectomy

,

liver cirrhosis

,

esophageal and gastric varices

,

cardiopulmonary bypass

,

,

vulvar neoplasms

,

,

,

,

,

inguinal hernia

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

postoperative pain

,

,

anastomotic leak

,

breast neoplasms

,

,

stomach neoplasms

,

soft tissue injuries

,

,

,

digestive system fistula

,

,

pancreatic neoplasms

,

,

,

liver transplantation

,

incisional hernia

,

squamous cell carcinoma

,

squamous cell neoplasms

,

,

,

,

,

,

,

,

gingival recession

,

knee osteoarthritis

,

,

,

alveolar bone loss

,

cerebrospinal fluid otorrhea

,

,

,

retinal detachment

,

,

minimally invasive surgical procedures

,

,

surgical staplers

,

conjunctival neoplasms

,

kidney neoplasms

,

pelvic organ prolapse

,

biliary fistula

,

microcirculation

,

,

kidney transplantation

,

,

replacement arthroplasty hip

,

femoracetabular impingement

,

gingival overgrowth

,

gingival hyperplasia

,

gingival hypertrophy

,

gastroesophageal reflux

,

,

,

congenital abnormalities

,

,

limbal stem cell deficiency

,

,

neurogenic urinary bladder

,

intra-articular fractures

,

fracture fixation

,

,

sinus floor augmentation

,

postoperative nausea and vomiting

,

bariatric surgery

,

healthy volunteers/patients

,

oroantral fistula

,

stress urinary incontinence

,

uterine prolapse

,

,

,

tissue preservation

,

paranasal sinus diseases

,

pilonidal sinus

,

pituitary neoplasms

,

tibial meniscus injuries

,

,

peripheral nerve injuries

,

anterior cruciate ligament injuries

,

anterior cruciate ligament reconstruction

,

intracranial hypertension

,

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