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Trade Name	Drug Name	Approved	Patent Expires	Indication
Hyftor	Sirolimus	2022-03-22	2029-2040	Kidney transplantation , Lymphangioleiomyomatosis , Perivascular epithelioid cell neoplasms , Graft rejection

Clinical Trials

Therapeutic Areas:

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Classification:

All

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Status:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

therapeutic equivalency

,

acanthosis nigricans

,

tuberous sclerosis

,

,

,

neurofibromatosis 1

,

neurofibromatoses

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

mantle-cell lymphoma

,

non-hodgkin lymphoma

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

,

myeloid leukemia acute

,

myeloid leukemia

ovarian neoplasms

,

ovarian epithelial carcinoma

healthy volunteers/patients

,

,

bacterial pneumonia

,

duchenne muscular dystrophy

,

muscular dystrophies

,

,

communicable diseases

healthy volunteers/patients

,

alzheimer disease

,

female genital neoplasms

,

,

chronic hepatitis b

,

,

major depressive disorder

,

depressive disorder

,

triple negative breast neoplasms

,

pancreatic neoplasms

,

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

sickle cell anemia

,

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

parkinson disease

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

chronic hepatitis

,

rectal neoplasms

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

stomach neoplasms

,

esophageal neoplasms

,

,

neoplasm metastasis

,

antiphospholipid syndrome

,

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

lupus nephritis

,

human influenza

,

breast neoplasms

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

non-hodgkin lymphoma

,

myeloid leukemia acute

,

multiple sclerosis

,

,

,

hepatocellular carcinoma

,

colonic neoplasms

,

thrombocytopenic purpura idiopathic

,

liver cirrhosis

,

neuromyelitis optica

,

membranous glomerulonephritis

,

chronic progressive multiple sclerosis

,

,

nephrotic syndrome

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

hemolytic anemia autoimmune

,

,

chronic hepatitis c

,

,

,

rheumatoid arthritis

,

,

,

juvenile arthritis

,

,

follicular lymphoma

,

,

,

myelodysplastic syndromes

,

,

,

acquired immunodeficiency syndrome

,

kidney transplantation

,

drug-related side effects and adverse reactions

,

heart disease risk factors

,

cognitive dysfunction

complex regional pain syndromes

,

,

,

,

,

,

stress urinary incontinence

,

,

prostatic hyperplasia

,

choroidal neovascularization

,

,

diabetes mellitus

,

magnetic resonance imaging

,

,

,

hypertrophic cicatrix

,

,

major depressive disorder

,

carpal tunnel syndrome

,

premature ejaculation

,

,

rectal neoplasms

,

low anterior resection syndrome

,

,

penile induration

,

thoracic outlet syndrome

,

postherpetic neuralgia

,

motor neuron disease

,

thyroid diseases

,

,

ovarian neoplasms

,

stomach neoplasms

,

head and neck neoplasms

,

esophageal neoplasms

,

,

urinary bladder neoplasms

,

small cell lung carcinoma

,

endophthalmitis

,

lacrimal apparatus diseases

,

,

radiation injuries

,

uveal neoplasms

,

,

pancreatic neoplasms

,

macular degeneration

,

,

breast neoplasms

,

myofascial pain syndromes

,

neurogenic urinary bladder

,

,

,

,

,

non-small-cell lung carcinoma

,

dystonic disorders

,

temporomandibular joint disorders

,

,

,

somatoform disorders

,

systemic scleroderma

,

raynaud disease

,

diffuse scleroderma

,

urinary bladder diseases

,

multiple sclerosis

,

,

postoperative pain

,

breast diseases

,

hereditary breast and ovarian cancer syndrome

,

,

,

,

patellofemoral pain syndrome

,

allergic conjunctivitis

,

,

muscle spasticity

,

overactive urinary bladder

,

urinary incontinence

,

migraine disorders

,

,

,

,

healthy volunteers/patients

,

,

,

dry eye syndromes

,

,

prostatic neoplasms

,

diabetic retinopathy

,

parkinson disease

,

,

,

,

,

chronic kidney failure

,

renal insufficiency

,

iron-deficiency anemia

,

iron deficiencies

,

,

interstitial cystitis

,

graves ophthalmopathy

,

,

,

spinal cord injuries

,

developmental disabilities

,

,

,

left ventricular hypertrophy

,

,

sjogren's syndrome

,

retinal vein occlusion

,

herpes labialis

,

traumatic brain injuries

,

,

,

,

keratoconjunctivitis sicca

,

,

,

muscle strength

,

clostridium botulinum type a

colorectal neoplasms

,

,

rectal neoplasms

,

squamous cell carcinoma of head and neck

,

chronic obstructive pulmonary disease

,

,

multiple myeloma

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

breast neoplasms

,

,

non-small-cell lung carcinoma

,

,

vision disorders

,

bcr-abl positive chronic myelogenous leukemia

,

neoplasm metastasis

,

,

,

,

myeloid leukemia

,

spondylarthritis

,

,

,

,

psoriatic arthritis

,

ankylosing spondylitis

,

retinal vein occlusion

,

,

chronic urticaria

,

,

cystic fibrosis

,

,

choroidal neovascularization

,

osteitis deformans

,

,

renal cell carcinoma

,

philadelphia chromosome

,

ovarian neoplasms

,

pituitary acth hypersecretion

,

,

,

myelodysplastic syndromes

,

,

thrombocytopenia

,

diabetic retinopathy

,

macular degeneration

,

,

hematologic diseases

,

sickle cell anemia

,

sickle cell trait

,

vaso-occlusive crises

,

,

,

,

,

neuroendocrine tumors

,

,

gastrointestinal stromal tumors

,

triple negative breast neoplasms

,

myeloid leukemia acute

,

acth-secreting pituitary adenoma

,

,

pseudomonas aeruginosa

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

respiratory aspiration

,

prostatic neoplasms

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

retinal diseases

,

wet macular degeneration

,

pathologic neovascularization

,

adenocarcinoma of lung

,

brain neoplasms

,

,

hepatocellular carcinoma

,

stomach neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

carcinoid tumor

,

malignant carcinoid syndrome

,

serotonin syndrome

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

homozygous familial hypercholesterolemia

,

,

lupus nephritis

,

,

axial spondyloarthritis

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

allergic rhinitis seasonal

,

graft vs host disease

,

primary myelofibrosis

,

,

inclusion body myositis

,

juvenile arthritis

,

hereditary autoinflammatory diseases

,

,

familial mediterranean fever

,

diabetes mellitus

,

retinal neovascularization

,

rheumatoid arthritis

,

hereditary sensory and autonomic neuropathies

,

,

hyperlipoproteinemia type i

,

hyperpituitarism

,

degenerative myopia

,

,

non-hodgkin lymphoma

,

,

pulmonary infarction

,

hodgkin disease

,

behcet syndrome

,

,

,

,

giant cell arteritis

,

,

hypersensitivity

,

food hypersensitivity

,

polymyalgia rheumatica

,

male breast neoplasms

,

follicular lymphoma

,

polycythemia vera

,

,

,

myeloid leukemia chronic-phase

,

,

left ventricular hypertrophy

,

pathologic dilatation

,

,

essential hypertension

,

systolic murmurs

,

disease progression

multiple myeloma

,

plasma cell neoplasms

,

myeloid leukemia acute

,

pancreatic neoplasms

,

,

myelodysplastic syndromes

,

myeloid leukemia

,

,

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

mantle-cell lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

,

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