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Trade Name	Drug Name	Approved	Patent Expires	Indication
Hyftor	Sirolimus	2022-03-22	2029-2040	Kidney transplantation , Lymphangioleiomyomatosis , Perivascular epithelioid cell neoplasms , Graft rejection

Clinical Trials

Therapeutic Areas:

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Classification:

All

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Status:

All

Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

diffuse intrinsic pontine glioma

,

parkinson disease

,

,

,

,

acquired immunodeficiency syndrome

,

,

connective tissue diseases

,

immune system diseases

,

rheumatic diseases

,

,

musculoskeletal diseases

,

collagen diseases

,

breast carcinoma in situ

,

leukemia myeloid chronic atypical bcr-abl negative

,

plasma cell leukemia

,

primary myelofibrosis

,

fallopian tube diseases

,

basal cell neoplasms

,

brain stem neoplasms

,

stem cell transplantation

,

hereditary breast and ovarian cancer syndrome

,

adenocarcinoma of lung

,

waldenstrom macroglobulinemia

,

paraproteinemias

,

precancerous conditions

,

smoldering multiple myeloma

,

mycobacterium avium-intracellulare infection

,

,

carcinoid tumor

,

healthy volunteers/patients

,

respiratory syncytial virus infections

,

,

,

phenylketonurias

,

myasthenia gravis

,

muscle weakness

,

acinar cell carcinoma

,

conjunctival neoplasms

,

,

clear cell sarcoma

,

gastrointestinal stromal tumors

,

salivary gland neoplasms

,

testicular neoplasms

,

breast diseases

,

medullary carcinoma

,

mammary paget's disease

,

thrombocytopenia

,

paroxysmal hemoglobinuria

,

,

parkinsonian disorders

,

pharmacokinetics

,

lymphatic metastasis

,

ovarian neoplasms

,

colorectal neoplasms

,

,

ovarian epithelial carcinoma

,

,

liver neoplasms

,

neoplasm metastasis

,

b-cell chronic lymphocytic leukemia

,

myeloproliferative disorders

,

hodgkin disease

,

fallopian tube neoplasms

,

kidney neoplasms

,

central nervous system neoplasms

,

nervous system neoplasms

,

b-cell lymphoma

,

brain neoplasms

,

myelomonocytic leukemia juvenile

,

myelodysplastic-myeloproliferative diseases

,

,

,

stomach neoplasms

,

rheumatoid arthritis

,

peritoneal neoplasms

,

myelomonocytic leukemia chronic

,

hematologic neoplasms

,

respiratory distress syndrome

,

,

colonic neoplasms

,

malignant mesothelioma

,

,

oligodendroglioma

,

rectal neoplasms

,

male breast neoplasms

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

,

,

ductal carcinoma

,

squamous cell carcinoma of head and neck

,

esophageal neoplasms

,

aplastic anemia

,

t-cell lymphoma

,

drug-related side effects and adverse reactions

,

,

merkel cell carcinoma

,

,

uterine cervical neoplasms

,

acute lung injury

,

newborn respiratory distress syndrome

,

myeloid leukemia chronic-phase

,

,

inflammatory breast neoplasms

,

invasive hydatidiform mole

,

t-cell lymphoma peripheral

,

mantle-cell lymphoma

,

,

,

t-cell lymphoma cutaneous

,

myelomonocytic leukemia acute

,

castration-resistant prostatic neoplasms

,

alzheimer disease

,

endometrial neoplasms

,

peripheral arterial disease

,

peripheral vascular diseases

,

mycobacterium infections

,

intraductal carcinoma noninfiltrating

,

respiratory aspiration

,

multiple sclerosis

,

small cell lung carcinoma

,

alveolar soft part sarcoma

,

nasopharyngeal carcinoma

,

burkitt lymphoma

,

immunoglobulin light-chain amyloidosis

,

bone marrow failure disorders

,

immunologic deficiency syndromes

,

intestinal neoplasms

,

basal cell carcinoma

,

large-cell lymphoma anaplastic

,

endometrioid carcinoma

,

,

severe acute respiratory syndrome-related coronavirus

,

primitive neuroectodermal tumors

,

neuroectodermal tumors

,

neuroendocrine tumors

,

severe acute respiratory syndrome

,

ductal carcinoma breast

,

,

cystic fibrosis

,

nontuberculous mycobacterium infections

,

pancreatic ductal carcinoma

,

cholangiocarcinoma

,

gallbladder neoplasms

,

myeloid leukemia accelerated phase

,

hypereosinophilic syndrome

,

residual neoplasm

,

appendiceal neoplasms

,

nasopharyngeal neoplasms

,

sickle cell anemia

,

beta-thalassemia

,

,

,

inborn errors metabolism

,

,

pulmonary hypertension

,

systemic scleroderma

,

,

interstitial lung diseases

,

diffuse scleroderma

,

lymphoproliferative disorders

,

,

sezary syndrome

,

mucinous adenocarcinoma

,

adenoid cystic carcinoma

,

mycosis fungoides

,

signet ring cell carcinoma

,

papillary adenocarcinoma

,

vulvar neoplasms

,

extramammary paget disease

,

keratoacanthoma

,

sweat gland neoplasms

,

basosquamous carcinoma

,

,

sebaceous adenocarcinoma

,

skin appendage carcinoma

,

glandular and epithelial neoplasms

,

thymus neoplasms

,

biliary tract neoplasms

,

second primary neoplasms

,

,

mucinous cystadenocarcinoma

,

serous cystadenocarcinoma

,

cystadenocarcinoma

,

,

,

malignant fibrous histiocytoma

,

,

viral pneumonia

,

adenocarcinoma in situ

,

,

cognitive dysfunction

,

,

,

,

unilateral breast neoplasms

,

hypersensitivity

,

kidney diseases

,

kidney transplantation

,

,

critical illness

,

immunosuppression therapy

,

,

trophoblastic neoplasms

,

,

,

,

,

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

erythroblastic leukemia acute

,

bile duct neoplasms

,

laryngeal neoplasms

,

,

,

chronic hepatitis c

,

ulcerative colitis

,

,

,

urologic neoplasms

,

,

,

,

,

soft tissue neoplasms

,

,

breast neoplasms

,

prostatic neoplasms

,

,

myelodysplastic syndromes

,

non-hodgkin lymphoma

,

,

,

,

pancreatic neoplasms

,

,

,

non-small-cell lung carcinoma

,

,

renal cell carcinoma

,

bcr-abl positive chronic myelogenous leukemia

,

,

pulmonary alveolar proteinosis

,

,

,

hepatocellular carcinoma

,

triple negative breast neoplasms

,

follicular lymphoma

,

,

squamous cell carcinoma

,

autoimmune diseases

,

communicable diseases

,

uveal neoplasms

,

rhabdomyosarcoma

,

,

large b-cell lymphoma diffuse

,

head and neck neoplasms

,

,

urinary bladder neoplasms

,

,

cutaneous malignant melanoma

,

,

,

,

squamous cell neoplasms

,

refractory anemia

,

ganglioneuroblastoma

,

,

transitional cell carcinoma

,

,

refractory anemia with excess of blasts

,

,

hematologic diseases

,

graft vs host disease

,

carcinoma in situ

,

radiation effects

,

coronavirus infections

,

,

alveolar rhabdomyosarcoma

,

embryonal rhabdomyosarcoma

,

cytomegalovirus retinitis

,

,

cutaneous leishmaniasis

,

,

multiple organ failure

,

neoplasms by histologic type

,

,

primitive neuroectodermal tumors peripheral

,

connective and soft tissue neoplasms

,

connective tissue neoplasms

,

bone tissue neoplasms

,

,

,

invasive fungal infections

,

adenoviridae infections

,

,

tongue neoplasms

,

,

,

,

,

multiple myeloma

,

plasma cell neoplasms

,

myeloid leukemia

,

myeloid leukemia acute

,

,

lymphoid leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

,

,

,

chronic hepatitis b

,

,

,

chronic hepatitis

,

,

,

,

respiratory insufficiency

,

wounds and injuries

,

,

spontaneous abortion

,

habitual abortion

,

,

,

,

intracytoplasmic sperm injections

,

liver cirrhosis

,

,

,

cytokine release syndrome

,

olfaction disorders

,

,

,

,

,

uterine neoplasms

,

female genital neoplasms

,

,

ovarian torsion

,

graft rejection

,

postoperative pain

,

,

non-alcoholic fatty liver disease

,

,

exocrine pancreatic insufficiency

,

periodontal diseases

,

,

,

mantle-cell lymphoma

,

,

myeloid leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia acute

healthy volunteers/patients

,

,

bacterial pneumonia

,

duchenne muscular dystrophy

,

muscular dystrophies

,

,

communicable diseases

hyperlipidemias

,

gastrointestinal stromal tumors

,

,

iron-deficiency anemia

,

iron deficiencies

,

,

,

,

small cell lung carcinoma

,

healthy volunteers/patients

,

,

,

primary myelofibrosis

,

myeloid leukemia acute

,

myeloid leukemia

,

prostatic neoplasms

,

hepatocellular carcinoma

,

,

plexiform neurofibroma

,

neurofibromatoses

,

,

,

,

chronic obstructive pulmonary disease

,

,

triple negative breast neoplasms

,

,

,

essential thrombocythemia

,

polycythemia vera

,

,

,

lupus nephritis

,

,

inflammatory breast neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

wiskott-aldrich syndrome

,

bcr-abl positive chronic myelogenous leukemia

,

,

graft vs host disease

,

hematopoietic stem cell transplantation

,

bronchiolitis obliterans syndrome

,

,

hyperlipoproteinemia type ii

,

organ transplantation

,

homozygous familial hypercholesterolemia

,

cryopyrin-associated periodic syndromes

,

myelodysplastic syndromes

,

,

liver transplantation

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

parkinson disease

,

,

,

juvenile arthritis

,

,

,

,

hepatitis b virus

,

,

,

,

vision disorders

,

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

,

acute coronary syndrome

,

,

,

pulmonary eosinophilia

,

pancreatic neoplasms

,

,

,

kidney transplantation

,

,

hypercholesterolemia

,

,

cardiovascular diseases

,

atherosclerosis

,

chronic kidney failure

,

kidney diseases

,

thrombocytopenia

,

breast neoplasms

,

,

renal insufficiency

,

,

,

,

chronic renal insufficiency

,

,

renal replacement therapy

,

drug-related side effects and adverse reactions

,

heart transplantation

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

,

cystic fibrosis

,

pseudomonas infections

,

type 2 diabetes mellitus

,

diabetes mellitus

,

multiple myeloma

,

plasma cell neoplasms

,

transplantation

,

cytomegalovirus infections

,

communicable diseases

,

metabolic syndrome

,

preconception care

,

drug interactions

,

percutaneous coronary intervention

,

,

atrial fibrillation

,

Microcrystalline cellulose

Potassium magnesium citrate (4:1:2)

Potassium nitrate

,

fallopian tube neoplasms

,

ovarian epithelial carcinoma

,

peritoneal neoplasms

,

parkinson disease

,

prostatic neoplasms

,

,

,

non-hodgkin lymphoma

,

follicular lymphoma

,

alzheimer disease

,

cognitive dysfunction

,

pulmonary alveolar proteinosis

,

,

myeloid leukemia acute

,

myeloid leukemia

,

,

corneal injuries

,

,

,

,

intraabdominal infections

,

intestinal fistula

,

skin transplantation

,

periodontal diseases

,

periodontal pocket

,

periodontal attachment loss

,

urethral stricture

,

abdominal hernia

,

internal hernia

,

fecal incontinence

,

,

,

chronic periodontitis

,

tendon injuries

,

rotator cuff injuries

,

,

,

,

,

pathologic processes

,

,

pulmonary emphysema

,

esophageal neoplasms

,

,

intracranial hypotension

,

,

foreign-body reaction

,

,

gastrointestinal diseases

,

digestive system diseases

,

humeral fractures

,

osteoporotic fractures

,

surgical anastomosis

,

femoral neck fractures

,

pleural effusion

,

esophageal stenosis

,

pathologic constriction

,

endoscopic mucosal resection

,

,

wounds and injuries

,

,

,

cerebrospinal fluid leak

,

postoperative hemorrhage

,

surgical blood loss

,

tympanic membrane perforation

,

,

,

cartilage diseases

,

postoperative complications

,

stress fractures

,

replacement arthroplasty knee

,

,

,

,

,

cartilage fractures

,

,

intervertebral disc degeneration

,

,

,

spinal cord injuries

,

cardiovascular diseases

,

,

,

thyroid neoplasms

,

vascular diseases

,

peripheral arterial disease

,

peripheral vascular diseases

,

osteochondritis

,

osteochondritis dissecans

,

,

,

femoral fractures

,

catheter ablation

,

,

,

,

,

inflammatory bowel diseases

,

segmental mastectomy

,

esophageal and gastric varices

,

,

cardiopulmonary bypass

,

,

vulvar neoplasms

,

,

,

,

,

,

inguinal hernia

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

postoperative pain

,

,

anastomotic leak

,

breast neoplasms

,

,

stomach neoplasms

,

digestive system fistula

,

soft tissue injuries

,

,

,

,

incisional hernia

,

,

pancreatic neoplasms

,

,

,

liver transplantation

,

squamous cell carcinoma

,

squamous cell neoplasms

,

gastric fistula

,

,

,

,

,

,

,

,

gingival recession

,

knee osteoarthritis

,

,

,

,

alveolar bone loss

,

,

,

retinal detachment

,

,

minimally invasive surgical procedures

,

,

surgical staplers

,

conjunctival neoplasms

,

kidney neoplasms

,

pelvic organ prolapse

,

biliary fistula

,

microcirculation

,

,

kidney transplantation

,

pancreatic fistula

,

,

replacement arthroplasty hip

,

femoracetabular impingement

,

gingival overgrowth

,

gingival hyperplasia

,

gingival hypertrophy

,

gastroesophageal reflux

,

,

,

congenital abnormalities

,

,

limbal stem cell deficiency

,

,

neurogenic urinary bladder

,

intra-articular fractures

,

fracture fixation

,

,

sinus floor augmentation

,

postoperative nausea and vomiting

,

bariatric surgery

,

,

,

healthy volunteers/patients

,

oroantral fistula

,

urinary incontinence

,

stress urinary incontinence

,

uterine prolapse

,

,

,

,

tissue preservation

,

paranasal sinus diseases

,

pilonidal sinus

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