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Company ReportsMadrigal Pharmaceuticals

Madrigal Pharmaceuticals(MDGL)

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Clinical Trials

Therapeutic Areas:

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Status:

All

Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

hepatic insufficiency

,

renal insufficiency

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

alcoholic fatty liver

,

acquired immunodeficiency syndrome

,

,

non-alcoholic fatty liver disease

,

,

,

liver cirrhosis

,

Aglatimagene besadenovec

prostatic neoplasms

Calcium dobesilate

non-hodgkin lymphoma

,

,

large b-cell lymphoma diffuse

,

non-hodgkin lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

,

immunologic deficiency syndromes

,

common variable immunodeficiency

,

,

,

rheumatoid arthritis

,

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

,

frontotemporal dementia

,

primary progressive aphasia

,

pick disease of the brain

small cell lung carcinoma

,

hepatocellular carcinoma

,

,

merkel cell carcinoma

,

non-muscle invasive bladder neoplasms

,

thyroid neoplasms

,

burkitt lymphoma

,

pancreatic ductal carcinoma

,

liver neoplasms

,

neurofibromatosis 1

,

hereditary sensory and autonomic neuropathies

,

,

,

drug interactions

,

transitional cell carcinoma

,

uterine cervical neoplasms

,

urinary bladder neoplasms

,

brain concussion

,

post-concussion syndrome

,

,

myeloproliferative disorders

,

b-cell chronic lymphocytic leukemia

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

t-cell lymphoma cutaneous

,

,

mycosis fungoides

,

squamous cell neoplasms

,

postoperative pain

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

lyme neuroborreliosis

,

ocular hypertension

,

open-angle glaucoma

,

,

multiple myeloma

,

neoplasm metastasis

,

brain neoplasms

,

,

ovarian epithelial carcinoma

,

,

respiratory syncytial viruses

,

,

,

plasma cell neoplasms

,

head and neck neoplasms

,

ovarian neoplasms

,

hodgkin disease

,

endometrial neoplasms

,

squamous cell carcinoma

,

atopic dermatitis

,

pancreatic neoplasms

,

,

respiratory tract infections

,

stomach neoplasms

,

esophageal neoplasms

,

hematopoietic stem cell transplantation

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

human influenza

,

oligodendroglioma

,

myelodysplastic syndromes

,

,

,

diabetic retinopathy

,

,

,

paraproteinemias

,

,

plasma cell leukemia

,

disease progression

,

,

overactive urinary bladder

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

communicable diseases

,

interstitial cystitis

,

meningococcal infections

,

meningococcal meningitis

,

,

serogroup b neisseria meningitidis

,

,

waldenstrom macroglobulinemia

,

,

myeloid leukemia

,

malignant mesothelioma

,

,

sickle cell anemia

,

,

monocytic leukemia acute

,

irritable bowel syndrome

,

,

small fiber neuropathy

,

myelomonocytic leukemia chronic

,

discoid lupus erythematosus

,

cutaneous lupus erythematosus

,

meningeal neoplasms

,

breast neoplasms

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

,

myeloid leukemia acute

,

prostatic neoplasms

,

renal cell carcinoma

,

non-hodgkin lymphoma

,

squamous cell carcinoma of head and neck

,

coronavirus infections

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

colonic neoplasms

,

,

rectal neoplasms

,

psoriatic arthritis

,

follicular lymphoma

,

,

borrelia infections

,

juvenile arthritis

,

,

,

,

partial epilepsies

,

kidney neoplasms

,

male breast neoplasms

,

bacterial infections

,

infectious skin diseases

,

wound infection

,

soft tissue infections

,

,

rectal diseases

,

,

chronic renal insufficiency

,

chronic kidney failure

,

,

endocrine system diseases

,

fetal growth retardation

,

growth disorders

,

hematologic neoplasms

,

invasive pulmonary aspergillosis

,

neuroaspergillosis

,

,

,

febrile neutropenia

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

gastrointestinal diseases

,

intestinal neoplasms

,

digestive system diseases

,

colonic diseases

,

intestinal diseases

,

,

bronchiolitis obliterans syndrome

,

lymphoid leukemia

,

restless legs syndrome

,

sleep deprivation

,

complex partial epilepsy

,

metabolic syndrome

,

abdominal obesity

,

pneumococcal infections

,

vector borne diseases

,

,

residual neoplasm

,

carpal tunnel syndrome

,

aplastic anemia

,

polyneuropathies

,

,

liver cirrhosis

,

,

rheumatoid arthritis

,

,

healthy volunteers/patients

,

,

,

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

type 2 diabetes mellitus

,

,

,

ankylosing spondylitis

,

pituitary dwarfism

,

,

,

invasive candidiasis

,

diabetes mellitus

,

,

kidney transplantation

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

,

,

,

pharmacokinetics

,

,

postherpetic neuralgia

,

axial spondyloarthritis

,

,

type 1 diabetes mellitus

,

insulin resistance

,

diabetic neuropathies

,

anxiety disorders

,

ventilator-associated pneumonia

,

relapsing-remitting multiple sclerosis

,

,

essential tremor

,

cardiovascular diseases

,

atherosclerosis

,

non-radiographic axial spondyloarthritis

,

electrocardiography

,

hemostatic disorders

,

smoking cessation

,

traumatic brain injuries

,

,

,

pathologic constriction

,

spinal stenosis

,

,

tissue adhesions

,

,

,

obsessive-compulsive disorder

,

rheumatic fever

,

,

,

,

neisseria meningitidis

,

ulcerative colitis

,

respiratory tract diseases

,

inflammatory bowel diseases

,

,

,

metabolic bone diseases

,

healthcare-associated pneumonia

,

drug-related side effects and adverse reactions

,

,

,

hypercholesterolemia

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

,

squamous cell carcinoma

,

healthy volunteers/patients

,

,

aids-related opportunistic infections

,

head and neck neoplasms

,

small cell carcinoma

,

follicular lymphoma

,

b-cell lymphoma

,

squamous cell neoplasms

,

heart disease risk factors

,

lipid metabolism disorders

,

renal cell carcinoma

,

castration-resistant prostatic neoplasms

,

small cell lung carcinoma

,

esophageal squamous cell carcinoma

,

,

pancreatic neoplasms

,

squamous cell carcinoma of head and neck

,

hodgkin disease

,

non-hodgkin lymphoma

,

esophageal neoplasms

,

hepatocellular carcinoma

,

liver neoplasms

,

,

urethral neoplasms

,

,

renal insufficiency

,

,

,

endometrial neoplasms

,

ureteral neoplasms

,

pelvic neoplasms

,

,

,

peritoneal neoplasms

,

microsatellite repeats

,

biliary liver cirrhosis

,

rectal neoplasms

,

pancreatic ductal carcinoma

,

triple negative breast neoplasms

,

breast neoplasms

,

non-small-cell lung carcinoma

,

stomach neoplasms

,

urinary bladder neoplasms

,

colorectal neoplasms

,

,

,

neoplasm metastasis

,

ovarian neoplasms

,

,

cholangiocarcinoma

,

biliary tract neoplasms

,

urologic neoplasms

,

,

,

gallbladder neoplasms

,

transitional cell carcinoma

,

fallopian tube neoplasms

,

bile duct neoplasms

,

uterine cervical neoplasms

,

large b-cell lymphoma diffuse

,

nasopharyngeal neoplasms

,

immunologic deficiency syndromes

,

antibiotic prophylaxis

,

malignant mesothelioma

,

liver cirrhosis

,

,

,

,

,

,

acquired immunodeficiency syndrome

,

,

,

chronic hepatitis b

,

,

,

cardiovascular diseases

,

,

,

,

immunosuppression therapy

,

,

rheumatoid arthritis

,

healthy volunteers/patients

,

,

pheochromocytoma

,

neuroendocrine tumors

,

,

meningeal carcinomatosis

,

,

laryngeal neoplasms

,

pancreatic ductal carcinoma

,

head and neck neoplasms

,

squamous cell neoplasms

,

transitional cell carcinoma

,

malignant pleural effusion

,

fallopian tube neoplasms

,

small cell carcinoma

,

gastrointestinal neoplasms

,

dna repair-deficiency disorders

,

urinary bladder neoplasms

,

salivary gland neoplasms

,

,

,

radiation injuries

,

radiation effects

,

germ cell and embryonal neoplasms

,

peritoneal neoplasms

,

,

pleural effusion

,

,

residual neoplasm

,

breast neoplasms

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

prostatic neoplasms

,

,

,

neoplasm metastasis

,

,

small cell lung carcinoma

,

,

,

,

,

rheumatoid arthritis

,

castration-resistant prostatic neoplasms

,

triple negative breast neoplasms

,

ovarian neoplasms

,

,

major depressive disorder

,

depressive disorder

,

,

gastroesophageal reflux

,

peptic esophagitis

,

,

colorectal neoplasms

,

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

endometrial neoplasms

,

,

renal cell carcinoma

,

urologic neoplasms

,

ovarian epithelial carcinoma

,

neoplasms by site

,

,

,

,

kidney diseases

,

,

cardiovascular diseases

,

pancreatic neoplasms

,

hypersensitivity

,

stomach neoplasms

,

sickle cell anemia

,

brain neoplasms

,

,

,

opioid-induced constipation

,

,

hypercholesterolemia

,

hepatocellular carcinoma

,

liver neoplasms

,

hereditary breast and ovarian cancer syndrome

,

,

chronic renal insufficiency

,

,

,

glucose metabolism disorders

,

metabolic diseases

,

endocrine system diseases

,

kidney neoplasms

,

,

zollinger-ellison syndrome

,

,

peptic ulcer hemorrhage

,

,

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

,

anxiety disorders

,

,

venous thrombosis

,

pulmonary embolism

,

plexiform neurofibroma

,

neurofibromatosis 1

,

neurofibromatoses

,

,

unknown primary neoplasms

,

respiratory insufficiency

,

myocardial infarction

,

coronary artery disease

,

bile duct neoplasms

,

cholangiocarcinoma

,

biliary tract neoplasms

,

,

gallbladder neoplasms

,

respiratory syncytial virus infections

,

uterine neoplasms

,

non-small-cell lung carcinoma

,

,

respiratory tract diseases

,

respiratory tract neoplasms

,

bronchogenic carcinoma

,

thoracic neoplasms

,

bronchial neoplasms

,

,

hematologic neoplasms

,

Globulin, immune

healthy volunteers/patients

,

bcr-abl positive chronic myelogenous leukemia

,

acquired immunodeficiency syndrome

,

,

,

,

glandular and epithelial neoplasms

,

,

gata2 deficiency

,

,

fallopian tube diseases

,

,

bronchiolitis obliterans syndrome

,

atopic dermatitis

,

,

,

myeloproliferative disorders

,

nerve sheath neoplasms

,

neoplasms by histologic type

,

adenosquamous carcinoma

,

,

central nervous system neoplasms

,

,

behcet syndrome

,

relapsing polychondritis

,

myasthenia gravis

,

mouth neoplasms

,

,

immunosuppression therapy

,

pancreatic neoplasms

,

transitional cell carcinoma

,

urologic neoplasms

,

,

squamous cell carcinoma

,

ovarian neoplasms

,

,

,

b-cell chronic lymphocytic leukemia

,

plasma cell neoplasms

,

malignant mesothelioma

,

biliary tract neoplasms

,

large b-cell lymphoma diffuse

,

,

uterine cervical neoplasms

,

castration-resistant prostatic neoplasms

,

endometrial neoplasms

,

pancreatic ductal carcinoma

,

uveal neoplasms

,

,

hematologic neoplasms

,

neoplasms by site

,

myeloid leukemia acute

,

squamous cell neoplasms

,

follicular lymphoma

,

microsatellite instability

,

t-cell lymphoma

,

graft vs host disease

,

b-cell lymphoma

,

neuroendocrine tumors

,

myelodysplastic syndromes

,

mantle-cell lymphoma

,

t-cell lymphoma peripheral

,

,

,

,

gastrointestinal neoplasms

,

adenocarcinoma of lung

,

cholangiocarcinoma

,

lymphoid leukemia

,

myeloid leukemia

,

interstitial lung diseases

,

urogenital neoplasms

,

merkel cell carcinoma

,

spinocerebellar degenerations

,

laryngeal diseases

,

,

,

psychology rejection

,

smoldering multiple myeloma

,

clear cell adenocarcinoma

,

,

,

,

rhabdomyosarcoma

,

b-cell leukemia

,

b-cell lymphoma marginal zone

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

prostatic diseases

,

penile neoplasms

,

,

autoimmune diseases

,

multiple sclerosis

,

waldenstrom macroglobulinemia

,

extranodal nk-t-cell lymphoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

burkitt lymphoma

,

female genital neoplasms

,

hypersensitivity

,

peritoneal neoplasms

,

salivary gland neoplasms

,

endometrioid carcinoma

,

,

,

organ transplantation

,

neuroendocrine carcinoma

,

urinary bladder diseases

,

carcinoid tumor

,

basal cell carcinoma

,

basal cell neoplasms

,

diffuse scleroderma

,

,

heart transplantation

,

,

male breast neoplasms

,

,

medulloblastoma

,

,

tertiary lymphoid structures

,

oropharyngeal neoplasms

,

,

non-muscle invasive bladder neoplasms

,

diffuse intrinsic pontine glioma

,

,

nephrotic syndrome

,

focal segmental glomerulosclerosis

,

lipoid nephrosis

,

common variable immunodeficiency

,

male genital neoplasms

,

large-cell lymphoma anaplastic

,

,

phenylketonurias

,

bile duct neoplasms

,

serous cystadenocarcinoma

,

papillary thyroid cancer

,

,

genetic therapy

,

uterine neoplasms

,

large cell carcinoma

,

endometrial stromal tumors

,

small cell carcinoma

,

adrenocortical carcinoma

,

thoracic neoplasms

,

,

thymus neoplasms

,

digestive system diseases

,

,

,

,

,

,

invasive hydatidiform mole

,

,

,

,

,

bronchiolo-alveolar adenocarcinoma

,

drug-related side effects and adverse reactions

,

thyroid neoplasms

,

precancerous conditions

,

bronchopulmonary dysplasia

,

tobacco smoking

,

meningeal carcinomatosis

,

systemic scleroderma

,

patient preference

,

,

oral leukoplakia

,

germ cell and embryonal neoplasms

,

churg-strauss syndrome

,

microscopic polyangiitis

,

,

oligodendroglioma

,

,

,

ankylosing spondylitis

,

,

alopecia areata

,

inflammatory breast neoplasms

,

,

,

gastrointestinal stromal tumors

,

male urogenital diseases

,

female urogenital diseases

,

female urogenital diseases and pregnancy complications

,

urogenital diseases

,

reactive arthritis

,

alzheimer disease

,

hereditary nonpolyposis colorectal neoplasms

,

,

,

,

colorectal neoplasms

,

neoplasm metastasis

,

squamous cell carcinoma of head and neck

,

prostatic neoplasms

,

breast neoplasms

,

liver neoplasms

,

head and neck neoplasms

,

multiple myeloma

,

,

hepatocellular carcinoma

,

urinary bladder neoplasms

,

,

stomach neoplasms

,

,

hodgkin disease

,

small cell lung carcinoma

,

brain neoplasms

,

colonic neoplasms

,

non-hodgkin lymphoma

,

triple negative breast neoplasms

,

rectal neoplasms

,

,

esophageal neoplasms

,

cutaneous malignant melanoma

,

,

ulcerative colitis

,

fallopian tube neoplasms

,

,

,

systemic lupus erythematosus

,

ovarian epithelial carcinoma

,

sjogren's syndrome

,

esophageal squamous cell carcinoma

,

,

juvenile arthritis

,

,

coronavirus infections

,

immunoglobulin g4-related disease

,

lupus nephritis

,

giant cell arteritis

,

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

polymyalgia rheumatica

,

,

respiratory tract diseases

,

vascular diseases

,

,

systemic vasculitis

,

disease progression

,

pathologic complete response

,

,

,

non-small-cell lung carcinoma

,

rheumatoid arthritis

,

renal cell carcinoma

,

,

kidney transplantation

,

kidney neoplasms

,

,

graft rejection

,

psoriatic arthritis

,

delayed graft function

,

chronic kidney failure

,

transplantation

,

,

epstein-barr virus infections

,

,

coronary artery disease

,

spondylarthritis

,

,

biliary liver cirrhosis

,

,

,

,

cardiomyopathies

,

dilated cardiomyopathy

,

type 1 diabetes mellitus

,

islets of langerhans transplantation

hematologic neoplasms

,

,

gastrointestinal stromal tumors

,

hodgkin disease

,

myeloid leukemia acute

,

breast neoplasms

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

,

chemotherapy-induced febrile neutropenia

,

non-hodgkin lymphoma

,

,

mantle-cell lymphoma

,

,

promyelocytic leukemia acute

,

hodgkin disease

,

myeloid leukemia acute

,

breast neoplasms

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

,

chemotherapy-induced febrile neutropenia

,

non-hodgkin lymphoma

,

,

mantle-cell lymphoma

,

,

promyelocytic leukemia acute

1

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