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Madrigal Pharmaceuticals
Madrigal Pharmaceuticals
(MDGL)
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Clinical Trials
Therapeutic Areas:
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Approval:
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Status:
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Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Resmetirom
healthy volunteers/patients
,
hepatic insufficiency
,
renal insufficiency
,
hypercholesterolemia
,
hyperlipoproteinemia type ii
,
alcoholic fatty liver
,
non-alcoholic fatty liver disease
,
fatty liver
,
liver diseases
,
liver cirrhosis
,
fibrosis
Aglatimagene besadenovec
breast neoplasms
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
hypersensitivity
Ganetespib
carcinoma
,
multiple myeloma
,
plasma cell neoplasms
,
transitional cell carcinoma
,
male breast neoplasms
,
esophageal neoplasms
,
hepatocellular carcinoma
,
liver neoplasms
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
bcr-abl positive chronic myelogenous leukemia
,
myeloid leukemia chronic-phase
,
blast crisis
,
lymphoid leukemia
,
myeloproliferative disorders
,
breast neoplasms
,
neoplasms
,
triple negative breast neoplasms
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
rectal neoplasms
,
prostatic neoplasms
,
ovarian neoplasms
,
sarcoma
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
small cell lung carcinoma
,
melanoma
,
hemangiosarcoma
,
gastrointestinal stromal tumors
,
malignant mesothelioma
,
mesothelioma
,
recurrence
,
neurofibrosarcoma
,
nerve sheath neoplasms
,
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
colonic neoplasms
,
pancreatic neoplasms
,
uveal neoplasms
,
lung neoplasms
,
non-small-cell lung carcinoma
,
adenocarcinoma
,
adenocarcinoma of lung
Calcium dobesilate
colorectal neoplasms
,
head and neck neoplasms
,
squamous cell carcinoma
,
squamous cell neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
multiple myeloma
,
plasma cell neoplasms
,
neoplasm metastasis
APILIMOD
non-hodgkin lymphoma
,
lymphoma
,
b-cell chronic lymphocytic leukemia
,
inflammation
,
immunologic deficiency syndromes
,
common variable immunodeficiency
,
crohn disease
,
covid-19
,
rheumatoid arthritis
,
arthritis
,
amyotrophic lateral sclerosis
,
motor neuron disease
,
sclerosis
,
dementia
,
frontotemporal dementia
,
primary progressive aphasia
,
pick disease of the brain
Bevifimod
multiple sclerosis
,
sclerosis
Edodekin alfa
psoriatic arthritis
,
arthritis
,
inflammatory bowel diseases
,
colitis
,
crohn disease
Elesclomol
neoplasms
,
prostatic neoplasms
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
recurrence
,
carcinoma
,
ovarian neoplasms
,
brenner tumor
,
endometrioid carcinoma
,
mucinous cystadenocarcinoma
,
mucinous adenocarcinoma
,
serous cystadenocarcinoma
,
fallopian tube neoplasms
,
transitional cell carcinoma
,
adenocarcinoma
,
clear cell adenocarcinoma
,
acinar cell carcinoma
,
cystadenocarcinoma
,
non-small-cell lung carcinoma
,
lung neoplasms
,
sarcoma
,
melanoma
,
alzheimer disease
,
cognitive dysfunction
Nepidermin
hypercholesterolemia
,
allergic rhinitis
,
rhinitis
,
asthma
,
hypertension
,
allergic rhinitis seasonal
,
allergic rhinitis perennial
,
hyperlipoproteinemia type ii
,
essential hypertension
,
infertility
,
fertilization in vitro
,
postoperative pain
,
osteoporosis
,
knee osteoarthritis
,
osteoarthritis
,
eczema
,
pruritus
,
dermatitis
,
chronic urticaria
,
urticaria
,
dysmenorrhea
,
toothache
,
schizophrenia
,
psychotic disorders
,
contraception
,
coronary disease
,
coronary artery disease
,
myocardial ischemia
,
heart diseases
,
ankylosing spondylitis
,
spondylarthritis
,
spondylitis
,
rheumatoid arthritis
,
arthritis
ROSABULIN
neoplasms
,
leukemia
,
hematologic neoplasms
,
lymphoma
Gonadotropin, chorionic
premature birth
,
hyperandrogenism
,
hypertension
,
fibrosis
,
cystic fibrosis
,
spondylarthritis
,
spondylitis
,
type 1 diabetes mellitus
,
non-alcoholic fatty liver disease
,
neuroblastoma
,
retinal diseases
,
hemophilia a
,
osteogenesis imperfecta
,
carcinoma
,
hepatocellular carcinoma
,
liver neoplasms
,
ankylosing spondylitis
,
inflammatory bowel diseases
,
spondylarthropathies
,
axial spondyloarthritis
,
gynatresia
,
pruritus
,
neurodermatitis
,
postoperative pain
,
oocyte retrieval
,
pulmonary arterial hypertension
,
familial primary pulmonary hypertension
,
healthy volunteers/patients
,
multiple myeloma
,
stroke
,
premature menopause
,
breast neoplasms
,
wounds and injuries
,
ischemic stroke
,
plasma cell neoplasms
,
azoospermia
,
graft vs host disease
,
leukemia
,
sinusitis
,
leiomyoma
,
urinary bladder neoplasms
,
cardiovascular diseases
,
diabetes mellitus
,
atrophy
,
respiratory tract diseases
,
human influenza
,
myelodysplastic syndromes
,
lymphoma
,
preleukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
systemic lupus erythematosus
,
salpingitis
,
ovulation inhibition
,
ovulation
,
traumatic brain injuries
,
brain injuries
,
endocrine system diseases
,
gonadal disorders
,
ovarian neoplasms
,
germ cell and embryonal neoplasms
,
testicular neoplasms
,
seminoma
,
dysgerminoma
,
germinoma
,
ataxia
,
wolfram syndrome
,
optic atrophy
,
respiratory tract infections
,
orthomyxoviridae infections
,
brain stem infarctions
,
sturge-weber syndrome
,
klippel-trenaunay-weber syndrome
,
adenoviridae infections
,
pharmacokinetics
,
endometrial neoplasms
,
vaping
,
dermatomyositis
,
non-small-cell lung carcinoma
,
infections
,
primary ovarian insufficiency
,
induced abortion
,
hiv infections
,
neoplasms
,
gestational trophoblastic disease
,
trophoblastic neoplasms
,
communicable diseases
,
covid-19
,
hiv
,
pre-eclampsia
,
anovulation
,
pituitary diseases
,
choriocarcinoma
,
virus diseases
,
fetal death
,
eclampsia
,
klinefelter syndrome
,
ulcer
,
insulin resistance
,
coronavirus infections
,
polyps
,
acquired immunodeficiency syndrome
,
fasting
,
telangiectasis
,
pressure ulcer
,
embryonic development
,
severe acute respiratory syndrome
,
night eating syndrome
,
adenomatous polyps
,
body weight
,
metabolic syndrome
,
body weight changes
,
primary hyperoxaluria
,
infertility
,
female infertility
,
syndrome
,
polycystic ovary syndrome
,
fertilization in vitro
,
pregnancy
,
hypogonadism
,
ovulation induction
,
embryo transfer
,
assisted reproductive techniques
,
pregnancy rate
,
habitual abortion
,
ectopic pregnancy
,
kallmann syndrome
,
recurrence
,
spontaneous abortion
,
ovarian hyperstimulation syndrome
,
premature cardiac complexes
,
obesity
,
intracytoplasmic sperm injections
,
fertility
,
endometriosis
,
ovarian reserve
,
hydatidiform mole
,
pregnancy outcome
,
tubal pregnancy
,
antiphospholipid syndrome
,
hereditary breast and ovarian cancer syndrome
,
flushing
,
emergencies
,
contraception
,
gastroesophageal reflux
,
type 2 diabetes mellitus
,
luteolysis
,
adiposity
,
psoriatic arthritis
,
arthritis
,
vitamin d deficiency
,
peptic esophagitis
,
bacterial infections
,
critical illness
,
aging
,
menopause
,
anesthesia
,
pregnancy tests
,
asthma
,
down syndrome
,
inflammation
,
liver diseases
,
melanoma
,
corpus luteum maintenance
,
premature obstetric labor
,
eunuchism
,
unplanned pregnancy
,
male infertility
,
alzheimer disease
,
smoking
,
depression
,
anxiety
,
hypersensitivity
,
sexually transmitted diseases
,
microbiota
,
glioblastoma
,
glioma
,
vulvodynia
,
vulvar vestibulitis
,
ovarian pregnancy
,
oogenesis
,
fertility preservation
,
myofibroma
,
trisomy 18 syndrome
,
trisomy 13 syndrome
,
trisomy
,
tissue adhesions
,
reproductive behavior
,
premature rupture fetal membranes
,
rupture
,
portal hypertension
,
multiple pregnancy
,
cesarean section
,
spinal cord injuries
,
chromosome aberrations
,
chromosome disorders
,
invasive hydatidiform mole
,
rheumatoid arthritis
,
glucose intolerance
,
atherosclerosis
,
venous thromboembolism
,
thrombosis
,
venous thrombosis
,
embolism
,
thromboembolism
,
blood coagulation disorders
,
hemostatic disorders
,
incomplete abortion
,
therapeutic abortion
,
menstrual cycle
,
dementia
,
hypoglycemia
,
starvation
,
neuralgia
,
restless legs syndrome
,
psychomotor agitation
,
sarcoidosis
,
pneumonia
,
psychological distress
,
nurse's role
,
gastrointestinal diseases
,
digestive system diseases
,
constipation
,
capsule endoscopy
,
dystonic disorders
,
dystonia
,
embryo implantation
,
body dysmorphic disorders
,
clostridium infections
,
fatty liver
,
hydrocephalus
,
streptococcus agalactiae
,
pregnancy complications
,
contraception behavior
,
substance-related disorders
,
prenatal care
,
amyotrophic lateral sclerosis
,
motor neuron disease
,
sclerosis
,
periodontal diseases
,
carcinogenesis
,
metabolic bone diseases
,
bone diseases
,
chronic obstructive pulmonary disease
,
osteoporosis
,
glaucoma
,
cardiotoxicity
,
lung neoplasms
,
depressive disorder
,
peripheral arterial disease
,
peripheral vascular diseases
,
vascular diseases
,
tetralogy of fallot
,
anxiety disorders
,
esophageal achalasia
,
iron overload
,
hemochromatosis
,
hemosiderosis
,
mortality
,
malnutrition
,
growth disorders
,
morbidity
,
failure to thrive
,
psychological stress
,
respiration disorders
,
postpartum period
,
dyskinesias
,
biliary dyskinesia
,
chlamydia infections
,
hypothyroidism
,
ventral hernia
,
hernia
,
nasal polyps
,
rhinosinusitis
,
in vitro oocyte maturation techniques
,
contracture
,
foreign bodies
,
foreign-body reaction
,
disease progression
,
electroacupuncture
,
acne vulgaris
,
diabetic foot
,
foot ulcer
,
oocyte donation
,
tuberculosis
,
hepatitis c
,
hepatitis b
,
hepatitis
,
hepatitis a
,
sexual behavior
,
adenomyosis
,
malaria
,
waldenstrom macroglobulinemia
,
weight loss
,
menstruation disturbances
,
hormone replacement therapy
,
pregnancy-induced hypertension
,
telomere
,
teratozoospermia
,
aneuploidy
,
blastocystis
,
papilloma
,
uterine cervical neoplasms
,
alphapapillomavirus
,
uterine cervical dysplasia
Biib028
neoplasms
,
adenocarcinoma
,
carcinoma
,
colonic neoplasms
,
rectal neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
stomach neoplasms
,
esophageal neoplasms
,
male breast neoplasms
,
colorectal neoplasms
,
pancreatic neoplasms
,
endometrial neoplasms
,
sarcoma
,
urinary bladder neoplasms
,
retinoblastoma
,
hidradenitis suppurativa
,
hidradenitis
,
breast neoplasms
,
melanoma
,
recurrence
,
multiple myeloma
,
plasma cell neoplasms
,
gastrointestinal stromal tumors
,
peripheral arterial disease
,
atherosclerosis
,
peripheral vascular diseases
Caelyx
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
Doxorubin
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
Sta9090
carcinoma
,
multiple myeloma
,
plasma cell neoplasms
,
transitional cell carcinoma
,
male breast neoplasms
,
esophageal neoplasms
,
hepatocellular carcinoma
,
liver neoplasms
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
bcr-abl positive chronic myelogenous leukemia
,
myeloid leukemia chronic-phase
,
blast crisis
,
lymphoid leukemia
,
myeloproliferative disorders
,
breast neoplasms
,
neoplasms
,
triple negative breast neoplasms
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
rectal neoplasms
,
prostatic neoplasms
,
ovarian neoplasms
,
sarcoma
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
small cell lung carcinoma
,
melanoma
,
hemangiosarcoma
,
gastrointestinal stromal tumors
,
malignant mesothelioma
,
mesothelioma
,
recurrence
,
neurofibrosarcoma
,
nerve sheath neoplasms
,
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
colonic neoplasms
,
pancreatic neoplasms
,
uveal neoplasms
,
lung neoplasms
,
non-small-cell lung carcinoma
,
adenocarcinoma
,
adenocarcinoma of lung
1
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