Loxo Oncology - PharmaKB

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Disease Reports

Company ReportsLoxo Oncology

Loxo Oncology(LOXO)

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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Jaypirca	Pirtobrutinib	2023-01-27	2036	Mantle-cell lymphoma

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

,

breast neoplasms

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

myeloid leukemia acute

,

myeloid leukemia

,

,

complex partial epilepsy

,

healthy volunteers/patients

blood coagulation disorders

,

hemostatic disorders

,

drug interactions

,

pharmacokinetics

,

,

interstitial lung diseases

,

cardiovascular diseases

,

,

non-alcoholic fatty liver disease

,

,

prostatic neoplasms

,

,

,

respiratory syncytial virus infections

,

,

alzheimer disease

,

systemic scleroderma

,

localized scleroderma

,

diffuse scleroderma

,

,

hepatic insufficiency

,

chronic kidney failure

,

pituitary acth hypersecretion

,

cushing syndrome

,

,

,

,

non-small-cell lung carcinoma

,

,

therapeutic equivalency

,

atopic dermatitis

,

lecithin cholesterol acyltransferase deficiency

,

,

,

transient ischemic attack

,

heart valve prosthesis

,

colorectal neoplasms

,

,

uveal neoplasms

,

,

staphylococcus aureus

,

cardiac catheterization

,

,

multi-infarct dementia

,

healthy volunteers/patients

,

intracranial hemorrhages

,

,

,

patent foramen ovale

,

replacement arthroplasty knee

,

,

intracranial sinus thrombosis

,

wounds and injuries

,

periodontal diseases

,

subdural hematoma

,

secondary prevention

,

neoplasm metastasis

,

,

knee osteoarthritis

,

,

replacement arthroplasty hip

,

liver cirrhosis

,

traumatic intracranial hemorrhage

,

cerebrovascular disorders

,

hypertensive intracranial hemorrhage

,

subarachnoid hemorrhage

,

cerebral intraventricular hemorrhage

,

cerebral small vessel diseases

,

electric countershock

,

migraine disorders

,

,

,

,

atrial fibrillation

,

thromboembolism

,

venous thromboembolism

,

,

,

,

ischemic stroke

,

venous thrombosis

,

,

coronary artery disease

,

,

pulmonary embolism

,

coronary disease

,

myocardial ischemia

,

acute coronary syndrome

,

myocardial infarction

,

,

drug-related side effects and adverse reactions

,

cerebral infarction

,

renal insufficiency

,

heart valve diseases

,

intracranial thrombosis

,

,

cerebral hemorrhage

,

atherosclerosis

,

,

replacement arthroplasty

,

chronic renal insufficiency

,

cognitive dysfunction

,

diabetes mellitus

,

,

percutaneous coronary intervention

,

,

staphylococcal infections

,

,

st elevation myocardial infarction

,

aortic valve disease

,

aortic valve stenosis

,

mitral valve stenosis

,

kidney diseases

,

ventricular tachycardia

,

ventricular premature complexes

,

intracranial embolism and thrombosis

,

angina pectoris

,

,

non-st elevated myocardial infarction

,

unstable angina

,

embolism and thrombosis

,

,

type 2 diabetes mellitus

,

,

cognition disorders

,

,

,

postoperative complications

,

postoperative hemorrhage

,

medication adherence

,

oral surgical procedures

,

therapeutic chemoembolization

,

postphlebitic syndrome

,

postthrombotic syndrome

,

hip osteoarthritis

,

blood coagulation tests

,

vascular diseases

,

arterial occlusive diseases

,

,

,

,

uterine hemorrhage

,

antiphospholipid syndrome

,

myeloproliferative disorders

,

craniocerebral trauma

,

,

retinal vein occlusion

,

stomatognathic diseases

,

thrombotic stroke

,

hemorrhagic disorders

,

recreational drug use

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

atrial remodeling

,

,

subdural hematoma chronic

,

,

intracranial arteriosclerosis

,

carotid stenosis

,

pathologic constriction

,

,

aortic diseases

,

central venous catheters

,

,

gastrointestinal hemorrhage

,

internal carotid artery dissection

healthy volunteers/patients

,

inflammatory bowel diseases

,

intestinal diseases

,

rheumatoid arthritis

,

,

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

b-cell lymphoma

,

interdigitating dendritic cell sarcoma

,

,

allergic rhinitis

,

,

allergic conjunctivitis

,

liver neoplasms

,

atopic dermatitis

,

,

neoplasm metastasis

,

healthy volunteers/patients

,

,

prostatic neoplasms

,

,

,

,

esophageal neoplasms

,

postoperative nausea and vomiting

,

brain neoplasms

,

second primary neoplasms

,

treatment-resistant depressive disorder

,

esophageal squamous cell carcinoma

,

renal cell carcinoma

,

experimental liver cirrhosis

,

chronic obstructive pulmonary disease

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

,

,

colorectal neoplasms

,

pancreatic ductal carcinoma

,

biliary tract neoplasms

,

non-muscle invasive bladder neoplasms

,

non-small-cell lung carcinoma

,

,

,

,

ovarian neoplasms

,

uterine cervical neoplasms

,

triple negative breast neoplasms

,

breast neoplasms

,

condylomata acuminata

,

hepatocellular carcinoma

,

,

immunologic deficiency syndromes

,

,

antibiotic prophylaxis

,

,

chronic hepatitis b

,

ovarian epithelial carcinoma

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

,

cystic fibrosis

,

pulmonary hypertension

,

pulmonary arterial hypertension

,

endometrial neoplasms

,

fallopian tube neoplasms

,

urinary bladder neoplasms

,

acquired immunodeficiency syndrome

,

,

chronic hepatitis c

,

,

,

,

,

neuromuscular blockade

,

hematologic neoplasms

,

hematopoietic stem cell transplantation

,

,

pseudomonas infections

,

pseudomonas aeruginosa

,

gram-negative bacterial infections

,

,

chronic kidney failure

,

kidney diseases

,

chronic hepatitis

,

intestinal diseases

,

,

non-hodgkin lymphoma

,

,

,

traumatic brain injuries

,

brain concussion

,

,

post-concussion syndrome

,

papillomavirus infections

,

uterine cervical dysplasia

,

ventilator-associated pneumonia

,

,

,

urinary tract infections

,

communicable diseases

,

bacterial pneumonia

,

,

,

chronic renal insufficiency

,

kidney diseases

,

hyperparathyroidism

,

vitamin d deficiency

,

neoplasm metastasis

,

chronic kidney failure

,

parathyroid diseases

,

secondary hyperparathyroidism

,

renal insufficiency

Globulin, immune

myelodysplastic syndromes

,

graft vs host disease

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

,

myeloid leukemia acute

,

hematologic neoplasms

,

discoid lupus erythematosus

,

lupus nephritis

,

central nervous system lupus vasculitis

,

,

systemic lupus erythematosus

,

central nervous system vasculitis

,

cutaneous lupus erythematosus

,

,

neoplasm metastasis

,

gastrointestinal neoplasms

,

biliary tract neoplasms

,

colorectal neoplasms

,

,

,

b-cell lymphoma

,

pancreatic neoplasms

,

mantle-cell lymphoma

,

,

,

urinary bladder neoplasms

,

liver cirrhosis

,

,

chronic hepatitis b

,

hepatocellular carcinoma

,

squamous cell carcinoma of head and neck

,

liver neoplasms

,

urologic neoplasms

,

transitional cell carcinoma

,

,

invasive hydatidiform mole

,

brain neoplasms

,

large b-cell lymphoma diffuse

,

b-cell leukemia

,

rectal neoplasms

,

castration-resistant prostatic neoplasms

,

,

endometrial neoplasms

,

esophageal neoplasms

,

uterine cervical neoplasms

,

ovarian epithelial carcinoma

,

colonic neoplasms

,

multiple myeloma

,

precursor cell lymphoblastic leukemia-lymphoma

,

plasma cell neoplasms

,

,

prolymphocytic leukemia

,

thyroid diseases

,

chronic renal insufficiency

,

kidney diseases

,

chronic hepatitis

,

prostatic neoplasms

,

renal cell carcinoma

,

,

small cell lung carcinoma

,

liver transplantation

,

,

non-alcoholic fatty liver disease

,

,

sclerosing cholangitis

,

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

large-cell lymphoma anaplastic

,

gastrointestinal diseases

,

,

relapsing-remitting multiple sclerosis

,

papillary thyroid cancer

,

medullary carcinoma

,

,

hairy cell leukemia

,

reactive arthritis

,

prolymphocytic leukemia b-cell

,

ovarian neoplasms

,

male breast neoplasms

,

,

thyroid neoplasms

,

anaplastic thyroid carcinoma

,

autoimmune diseases

,

respiratory syncytial virus infections

,

,

mouth neoplasms

,

oropharyngeal neoplasms

,

laryngeal neoplasms

,

hypopharyngeal neoplasms

,

,

b-cell chronic lymphocytic leukemia

,

,

breast neoplasms

,

non-hodgkin lymphoma

,

,

lymphoid leukemia

,

non-small-cell lung carcinoma

,

follicular lymphoma

,

triple negative breast neoplasms

,

waldenstrom macroglobulinemia

,

b-cell lymphoma marginal zone

,

stomach neoplasms

,

rheumatoid arthritis

,

psoriatic arthritis

,

,

,

,

,

acquired immunodeficiency syndrome

,

,

hepatitis b virus

,

chronic hepatitis c

,

atrial fibrillation

,

cardiac arrhythmias

,

cystic fibrosis

uveal neoplasms

,

,

,

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