Loxo Oncology - PharmaKB

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Disease Reports

Company ReportsLoxo Oncology

Loxo Oncology(LOXO)

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Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Jaypirca	Pirtobrutinib	2023-01-27	2036	Mantle-cell lymphoma

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

,

non-alcoholic fatty liver disease

,

,

alzheimer disease

,

,

hepatic insufficiency

,

chronic renal insufficiency

,

chronic kidney failure

,

cardiovascular diseases

,

coronary disease

,

acute coronary syndrome

,

cardiac catheterization

,

heart valve prosthesis

,

venous thrombosis

,

,

,

replacement arthroplasty knee

,

secondary prevention

,

neoplasm metastasis

,

replacement arthroplasty hip

,

,

,

percutaneous coronary intervention

,

intracranial sinus thrombosis

,

atrial fibrillation

,

thromboembolism

,

venous thromboembolism

,

,

renal insufficiency

,

replacement arthroplasty

,

heart valve diseases

,

coronary artery disease

,

myocardial ischemia

,

cognitive dysfunction

,

,

,

cerebral infarction

,

myocardial infarction

,

,

,

,

cognition disorders

,

,

blood coagulation tests

,

drug-related side effects and adverse reactions

,

blood coagulation disorders

,

hemostatic disorders

,

hemorrhagic disorders

,

medication adherence

,

recreational drug use

,

,

transient ischemic attack

healthy volunteers/patients

,

,

communicable diseases

,

helicobacter infections

,

sickle cell anemia

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

b-cell lymphoma

,

interdigitating dendritic cell sarcoma

psoriatic arthritis

,

rheumatoid arthritis

,

breast neoplasms

,

non-hodgkin lymphoma

,

colorectal neoplasms

Globulin, immune

inflammatory breast neoplasms

,

,

,

,

,

oligodendroglioma

,

small cell lung carcinoma

,

paroxysmal hemoglobinuria

,

,

systemic lupus erythematosus

,

microsatellite repeats

,

stomach neoplasms

,

neoplasm metastasis

,

non-hodgkin lymphoma

,

esophageal neoplasms

,

hodgkin disease

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

liver neoplasms

,

squamous cell carcinoma of head and neck

,

,

,

hepatocellular carcinoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

pancreatic neoplasms

,

prolymphocytic leukemia

,

prostatic neoplasms

,

ovarian neoplasms

,

bronchiolitis obliterans syndrome

,

hypercholesterolemia

,

h1n1 subtype influenza a virus

,

aplastic anemia

,

biliary tract neoplasms

,

renal cell carcinoma

,

,

,

triple negative breast neoplasms

,

head and neck neoplasms

,

atopic dermatitis

,

basal cell carcinoma

,

basal cell neoplasms

,

heart transplantation

,

fallopian tube neoplasms

,

rectal neoplasms

,

pancreatic ductal carcinoma

,

induction chemotherapy

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

renal insufficiency

,

brain neoplasms

,

follicular lymphoma

,

,

lymphoid leukemia

,

meningococcal meningitis

,

neisseria meningitidis

,

west nile fever

,

systemic scleroderma

,

diffuse scleroderma

,

refractory anemia with excess of blasts

,

refractory anemia

,

esophageal squamous cell carcinoma

,

uterine cervical neoplasms

,

,

,

paraproteinemias

,

ovarian epithelial carcinoma

,

squamous cell carcinoma

,

squamous cell neoplasms

,

prolymphocytic leukemia t-cell

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

uveal neoplasms

,

,

sezary syndrome

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

,

hyperlipoproteinemia type ii

,

,

t-cell lymphoma peripheral

,

laryngeal neoplasms

,

stem cell transplantation

,

colonic neoplasms

,

multiple myeloma

,

breast neoplasms

,

,

non-small-cell lung carcinoma

,

,

b-cell chronic lymphocytic leukemia

,

colorectal neoplasms

,

myelodysplastic syndromes

,

plasma cell neoplasms

,

,

myeloid leukemia acute

,

,

graft vs host disease

,

,

,

meningococcal infections

,

human influenza

,

,

hematologic neoplasms

,

,

graft rejection

,

,

bcr-abl positive chronic myelogenous leukemia

,

rheumatoid arthritis

,

thrombotic thrombocytopenic purpura

,

immune system diseases

,

,

haemophilus influenzae type b

,

reperfusion injury

,

,

neuroendocrine tumors

,

carcinoid tumor

,

,

paraneoplastic syndromes

,

islet cell carcinoma

,

islet cell adenoma

,

,

,

somatostatinoma

,

respiratory hypersensitivity

,

,

,

glomerulonephritis

,

haemophilus infections

,

myeloid leukemia

,

autoimmune diseases

,

nervous system diseases

,

autoimmune diseases of the nervous system

,

demyelinating diseases

,

cns demyelinating autoimmune diseases

,

myeloproliferative disorders

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

multiple sclerosis

,

,

,

relapsing-remitting multiple sclerosis

,

kidney transplantation

,

,

,

chronic kidney failure

,

,

,

type 1 diabetes mellitus

,

,

glycogen storage disease type ii

,

,

liver transplantation

,

psychology rejection

,

transplantation

,

immunosuppression therapy

,

glycogen storage disease type iii

,

,

mucopolysaccharidosis i

,

kidney diseases

,

diabetes mellitus

,

b-cell leukemia

,

,

clostridium infections

,

vaccine immunogenicity

,

pathologic processes

,

healthy volunteers/patients

atrial fibrillation

,

cardiac arrhythmias

,

,

,

non-hodgkin lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

macular degeneration

,

,

communicable diseases

,

bacterial infections

,

methicillin-resistant staphylococcus aureus

,

staphylococcal skin infections

,

infectious skin diseases

,

bacterial skin diseases

,

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