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Loxo Oncology
Loxo Oncology
(LOXO)
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Jaypirca
Pirtobrutinib
2023-01-27
2036
Mantle-cell lymphoma
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Pirtobrutinib
healthy volunteers/patients
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
myeloid leukemia
,
preleukemia
,
multiple myeloma
,
burkitt lymphoma
,
renal insufficiency
,
liver failure
,
hepatic insufficiency
,
b-cell lymphoma marginal zone
,
waldenstrom macroglobulinemia
,
b-cell lymphoma
,
follicular lymphoma
,
syndrome
,
large b-cell lymphoma diffuse
,
hematologic neoplasms
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
sclerosis
,
thrombocytopenic purpura idiopathic
,
thrombocytopenia
,
mantle-cell lymphoma
,
b-cell leukemia
,
lymphoma
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
leukemia
,
non-hodgkin lymphoma
,
atrial fibrillation
,
cardiac arrhythmias
,
heart arrest
,
supraventricular tachycardia
Dabigatran
healthy volunteers/patients
,
overweight
,
covid-19
,
atrial fibrillation
,
embolism
,
venous thromboembolism
,
thromboembolism
,
hemorrhage
,
stroke
,
neoplasms
,
thrombosis
Antithrombin iii
streptococcal infections
,
rectal neoplasms
,
meningioma
,
atrial fibrillation
,
mantle-cell lymphoma
,
multiple myeloma
,
plasma cell neoplasms
,
gliosarcoma
,
central nervous system neoplasms
,
nervous system neoplasms
,
colonic neoplasms
,
streptococcus agalactiae
,
breast neoplasms
,
neoplasms
,
arthritis
,
ankylosing spondylitis
,
spondylarthritis
,
spondylitis
,
non-small-cell lung carcinoma
,
lung neoplasms
,
prostatic neoplasms
,
psoriatic arthritis
,
meningococcal infections
,
leukemia
,
carcinoma
,
bcr-abl positive chronic myelogenous leukemia
,
lymphoma
,
sickle cell anemia
,
melanoma
,
renal cell carcinoma
,
macular edema
,
edema
,
vision disorders
,
low vision
,
meningitis
,
meningococcal meningitis
,
uveitis
,
thrombocytopenia
,
sarcoma
,
neuroendocrine tumors
,
glioblastoma
,
myeloid leukemia
,
ovarian neoplasms
,
human influenza
,
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
gastrointestinal neoplasms
,
digestive system neoplasms
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
hepatocellular carcinoma
,
carcinoid tumor
,
malignant carcinoid syndrome
,
serotonin syndrome
,
astrocytoma
,
hypercholesterolemia
,
hyperlipoproteinemia type ii
,
homozygous familial hypercholesterolemia
,
chronic obstructive pulmonary disease
,
lung diseases
,
obstructive lung diseases
,
gastrointestinal stromal tumors
,
philadelphia chromosome
,
ovarian epithelial carcinoma
,
axial spondyloarthritis
,
allergic rhinitis
,
rhinitis
,
allergic rhinitis seasonal
,
graft vs host disease
,
pituitary acth hypersecretion
,
acth-secreting pituitary adenoma
,
rheumatoid arthritis
,
psoriasis
,
hepatitis b
,
whooping cough
,
tetanus
,
diphtheria
,
haemophilus influenzae
,
non-hodgkin lymphoma
,
b-cell lymphoma
,
acromegaly
,
hodgkin disease
,
recurrence
,
arteritis
,
giant cell arteritis
,
polymyalgia rheumatica
,
follicular lymphoma
,
pancreatic neoplasms
,
fistula
,
myeloid leukemia chronic-phase
,
neuroendocrine carcinoma
,
lupus nephritis
,
nephritis
,
heart failure
,
hypertension
,
essential hypertension
,
systolic murmurs
,
multiple sclerosis
,
neoplasm metastasis
,
chronic progressive multiple sclerosis
,
sclerosis
,
small cell lung carcinoma
Vitamin e
respiratory aspiration
,
healthy volunteers/patients
Vitamin k
venous thromboembolism
,
thromboembolism
,
pulmonary embolism
,
embolism
,
thrombosis
,
venous thrombosis
Terfenadine
healthy volunteers/patients
,
lymphoma
,
aggression
,
colorectal neoplasms
,
colonic neoplasms
,
exanthema
,
breast neoplasms
,
multiple myeloma
,
plasma cell neoplasms
,
ulcer
,
gout
,
juvenile arthritis
,
arthritis
Tirabrutinib
sjogren's syndrome
,
syndrome
Serine
healthy volunteers/patients
,
crush injuries
,
overweight
,
covid-19
,
pneumonia
,
inflammation
,
pulmonary embolism
,
heart diseases
,
cerebral infarction
,
ischemic stroke
,
chronic kidney failure
,
kidney diseases
,
leukemia
,
lymphoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
atrial fibrillation
,
thrombosis
,
thromboembolism
,
embolism
,
venous thromboembolism
,
venous thrombosis
,
stroke
,
acute coronary syndrome
,
syndrome
,
hemorrhage
,
obesity
,
neoplasms
,
osteoporosis
Bevifimod
hemophilia a
,
hemophilia b
Nadide
diabetic neuropathies
,
peripheral nervous system diseases
,
neuralgia
,
postherpetic neuralgia
,
pain
Polyglycolic acid
rectal neoplasms
,
esophageal neoplasms
,
pancreatic neoplasms
,
disease progression
,
lymphoma
,
neoplasm metastasis
,
kidney diseases
,
kidney transplantation
,
lung neoplasms
,
neoplasms
,
stomach neoplasms
,
colonic neoplasms
,
malignant mesothelioma
,
mesothelioma
,
arteritis
,
giant cell arteritis
,
polymyalgia rheumatica
,
juvenile arthritis
,
carcinoma
,
head and neck neoplasms
,
respiratory tract diseases
,
germ cell and embryonal neoplasms
,
small cell lung carcinoma
,
lung diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
thoracic neoplasms
,
bronchial diseases
,
neoplasms by histologic type
,
neoplasms by site
,
nerve tissue neoplasms
,
systemic lupus erythematosus
,
arthritis
,
rheumatoid arthritis
,
non-small-cell lung carcinoma
,
colorectal neoplasms
,
adenocarcinoma
,
adenocarcinoma of lung
,
bronchitis
,
acute disease
,
graft vs host disease
,
hematopoietic stem cell transplantation
Retinol
ovulation inhibition
,
psoriasis
,
healthy volunteers/patients
,
prostatic neoplasms
,
esophageal neoplasms
,
ovarian neoplasms
,
stomach neoplasms
,
erythema
,
skin abnormalities
,
colorectal neoplasms
,
adenocarcinoma
,
chronic kidney failure
,
kidney diseases
,
thrombosis
,
venous thrombosis
,
venous thromboembolism
,
thromboembolism
,
contraception
,
transcatheter aortic valve replacement
,
memory disorders
,
multiple sclerosis
,
sclerosis
,
percutaneous coronary intervention
,
neoplasms
,
exanthema
,
atrial fibrillation
,
pulmonary embolism
,
embolism
,
energy metabolism
,
calcinosis
,
acute coronary syndrome
,
ischemic stroke
,
atopic dermatitis
,
dermatitis
,
avitaminosis
Endocrine
renal cell carcinoma
,
carcinoma
,
non-small-cell lung carcinoma
,
endometrial neoplasms
,
hepatocellular carcinoma
,
stomach neoplasms
,
melanoma
,
liver neoplasms
,
mesothelioma
,
gastrointestinal neoplasms
,
female genital neoplasms
,
neuroendocrine tumors
,
type 2 diabetes mellitus
,
diabetes mellitus
,
hypertension
,
breast neoplasms
Mk3475
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
myeloid leukemia acute
,
myeloid leukemia
,
small cell lung carcinoma
,
head and neck neoplasms
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
squamous cell neoplasms
,
thoracic neoplasms
,
neoplasms
,
leukemia
,
sarcoma
,
carcinoma
,
hemangiosarcoma
,
hepatocellular carcinoma
,
liver neoplasms
,
precursor cell lymphoblastic leukemia-lymphoma
,
biphenotypic leukemia acute
,
lymphoid leukemia
,
renal cell carcinoma
,
kidney neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
melanoma
LY3410738
healthy volunteers/patients
,
neoplasms
,
leukemia
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
hematologic neoplasms
,
myeloproliferative disorders
,
myelomonocytic leukemia chronic
,
myeloid leukemia
,
myelomonocytic leukemia juvenile
,
preleukemia
,
glioma
,
cholangiocarcinoma
,
chondrosarcoma
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