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Loxo Oncology
Loxo Oncology
(LOXO)
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Jaypirca
Pirtobrutinib
2023-01-27
2036
Mantle-cell lymphoma
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Pirtobrutinib
healthy volunteers/patients
,
follicular lymphoma
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
myeloid leukemia
,
preleukemia
,
multiple myeloma
,
burkitt lymphoma
,
renal insufficiency
,
liver failure
,
hepatic insufficiency
,
b-cell lymphoma marginal zone
,
waldenstrom macroglobulinemia
,
b-cell lymphoma
,
syndrome
,
large b-cell lymphoma diffuse
,
reactive arthritis
,
hematologic neoplasms
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
sclerosis
,
thrombocytopenic purpura idiopathic
,
thrombocytopenia
,
mantle-cell lymphoma
,
b-cell leukemia
,
lymphoma
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
leukemia
,
non-hodgkin lymphoma
,
atrial fibrillation
,
cardiac arrhythmias
,
heart arrest
,
supraventricular tachycardia
Dabigatran
healthy volunteers/patients
,
prostatic neoplasms
,
hot flashes
,
non-small-cell lung carcinoma
,
hematoma
,
atrial fibrillation
,
venous thromboembolism
,
thromboembolism
,
thrombosis
,
ischemic stroke
,
stroke
Vitamin e
muscular atrophy
,
spinal muscular atrophy
,
neoplasms
,
atherosclerosis
Vitamin k
healthy volunteers/patients
,
colorectal neoplasms
,
thrombosis
,
venous thrombosis
,
venous thromboembolism
,
thromboembolism
,
heart diseases
,
rheumatic heart disease
,
rheumatic diseases
,
transcatheter aortic valve replacement
,
percutaneous coronary intervention
,
atrial fibrillation
,
pulmonary embolism
,
embolism
,
calcinosis
,
acute coronary syndrome
,
ischemic stroke
,
renal insufficiency
,
stroke
Terfenadine
healthy volunteers/patients
,
psoriasis
,
systemic lupus erythematosus
,
fibrosis
,
multiple myeloma
,
plasma cell neoplasms
,
colorectal neoplasms
,
rectal neoplasms
,
chronic urticaria
,
urticaria
,
immunoglobulin g4-related disease
,
hiv infections
,
hiv
Tirabrutinib
leukemia
,
lymphoma
,
b-cell chronic lymphocytic leukemia
,
b-cell lymphoma marginal zone
,
mantle-cell lymphoma
,
waldenstrom macroglobulinemia
,
b-cell lymphoma
,
lymphoid leukemia
Serine
invasive candidiasis
,
candidiasis
,
aspergillosis
,
invasive pulmonary aspergillosis
Bevifimod
healthy volunteers/patients
,
hepatic insufficiency
,
ovarian epithelial carcinoma
,
castration-resistant prostatic neoplasms
,
myeloid leukemia acute
,
myeloid leukemia
,
liver failure
,
uveal neoplasms
,
uveal melanoma
,
liver diseases
,
huntington disease
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
hiv seropositivity
,
sarcoma
,
central nervous system neoplasms
,
mantle-cell lymphoma
,
non-hodgkin lymphoma
,
uterine cervical neoplasms
,
plasma cell neoplasms
,
salivary gland neoplasms
,
cholangiocarcinoma
,
neuroendocrine tumors
,
hepatitis b
,
chronic hepatitis b
,
hepatitis
,
hepatitis a
,
unknown primary neoplasms
,
lobular carcinoma
,
invasive hydatidiform mole
,
ischemia
,
coronary artery disease
,
myocardial ischemia
,
gastrointestinal neoplasms
,
respiratory tract diseases
,
digestive system neoplasms
,
gastrointestinal diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
thoracic neoplasms
,
intestinal neoplasms
,
digestive system diseases
,
colonic diseases
,
intestinal diseases
,
bronchial neoplasms
,
waldenstrom macroglobulinemia
,
follicular lymphoma
,
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
exanthema
,
uterine neoplasms
,
female genital neoplasms
,
bronchiolo-alveolar adenocarcinoma
,
glioblastoma
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
neoplasms
,
breast neoplasms
,
carcinoma
,
colorectal neoplasms
,
triple negative breast neoplasms
,
lymphoma
,
hepatocellular carcinoma
,
liver neoplasms
,
renal cell carcinoma
,
leukemia
,
ovarian neoplasms
,
neoplasm metastasis
,
brain neoplasms
,
b-cell chronic lymphocytic leukemia
,
head and neck neoplasms
,
lymphoid leukemia
,
hematologic neoplasms
,
prostatic neoplasms
,
multiple myeloma
,
thyroid neoplasms
,
papillary thyroid cancer
,
large-cell lymphoma anaplastic
,
neoplasms by site
,
glioma
,
thyroid diseases
,
lymphoproliferative disorders
,
neoplasms by histologic type
,
malignant mesothelioma
,
mesothelioma
,
neuroblastoma
,
anaplastic thyroid carcinoma
,
laryngeal neoplasms
,
erdheim-chester disease
,
mucinous adenocarcinoma
,
ductal carcinoma breast
,
inflammatory breast neoplasms
,
kidney transplantation
,
bcr-abl positive chronic myelogenous leukemia
,
non-small-cell lung carcinoma
,
lung neoplasms
,
melanoma
,
hiv infections
,
pancreatic neoplasms
,
infections
,
communicable diseases
,
adenocarcinoma
,
acquired immunodeficiency syndrome
,
disease progression
,
adenocarcinoma of lung
,
kidney diseases
,
polyomavirus infections
,
liver cirrhosis
,
cardiotoxicity
,
fibrosis
,
hemorrhage
,
endometrial neoplasms
,
uterine hemorrhage
,
postmenopause
,
hiv-1
,
alzheimer disease
,
frontotemporal dementia
,
progressive supranuclear palsy
,
primary progressive aphasia
,
pick disease of the brain
,
hodgkin disease
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
Nadide
skin diseases
,
papulosquamous skin diseases
Polyglycolic acid
rectal neoplasms
,
esophageal neoplasms
,
pancreatic neoplasms
,
disease progression
,
lymphoma
,
neoplasm metastasis
,
kidney diseases
,
kidney transplantation
,
lung neoplasms
,
neoplasms
,
stomach neoplasms
,
colonic neoplasms
,
malignant mesothelioma
,
mesothelioma
,
arteritis
,
giant cell arteritis
,
polymyalgia rheumatica
,
juvenile arthritis
,
carcinoma
,
head and neck neoplasms
,
respiratory tract diseases
,
germ cell and embryonal neoplasms
,
small cell lung carcinoma
,
lung diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
thoracic neoplasms
,
bronchial diseases
,
neoplasms by histologic type
,
neoplasms by site
,
nerve tissue neoplasms
,
systemic lupus erythematosus
,
arthritis
,
rheumatoid arthritis
,
non-small-cell lung carcinoma
,
colorectal neoplasms
,
adenocarcinoma
,
adenocarcinoma of lung
,
bronchitis
,
acute disease
,
graft vs host disease
,
hematopoietic stem cell transplantation
Retinol
neoplasms
,
breast neoplasms
,
carcinoma
,
triple negative breast neoplasms
,
fallopian tube neoplasms
,
squamous cell carcinoma of head and neck
,
small cell lung carcinoma
,
squamous cell carcinoma
,
esophageal squamous cell carcinoma
,
pharyngeal neoplasms
,
peritoneal neoplasms
,
healthy volunteers/patients
,
head and neck neoplasms
,
atrial fibrillation
,
stomach neoplasms
,
ovarian neoplasms
,
pancreatic ductal carcinoma
,
biliary tract neoplasms
,
non-small-cell lung carcinoma
,
esophageal neoplasms
,
ocular hypertension
,
castration-resistant prostatic neoplasms
,
endometrial neoplasms
,
adenocarcinoma
,
lung neoplasms
,
pneumonia
,
lung injury
,
colorectal neoplasms
,
diabetes mellitus
,
type 1 diabetes mellitus
,
schizophrenia
,
psychotic disorders
,
mental disorders
,
metabolic diseases
,
calcium metabolism disorders
Endocrine
neoplasm metastasis
,
carcinoma
,
carcinoid tumor
,
neuroendocrine carcinoma
,
recurrence
,
prostatic neoplasms
,
breast diseases
,
islet cell carcinoma
,
malignant carcinoid syndrome
,
serotonin syndrome
,
breast neoplasms
,
neuroendocrine tumors
,
neoplasms
,
triple negative breast neoplasms
,
endocrine gland neoplasms
,
pancreatic neoplasms
,
male breast neoplasms
,
heart failure
,
thalassemia
,
islet cell adenoma
,
iron overload
,
disease progression
Mk3475
ovarian neoplasms
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
peritoneal neoplasms
,
endometrial neoplasms
LY3410738
healthy volunteers/patients
Gluconorm
gastrointestinal stromal tumors
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