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Loxo Oncology
Loxo Oncology
(LOXO)
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Jaypirca
Pirtobrutinib
2023-01-27
2036
Mantle-cell lymphoma
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Pirtobrutinib
healthy volunteers/patients
,
renal insufficiency
,
liver failure
,
hepatic insufficiency
,
b-cell lymphoma marginal zone
,
waldenstrom macroglobulinemia
,
follicular lymphoma
,
interdigitating dendritic cell sarcoma
,
large b-cell lymphoma diffuse
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
sclerosis
,
b-cell chronic lymphocytic leukemia
,
non-hodgkin lymphoma
,
b-cell lymphoma
,
lymphoid leukemia
,
mantle-cell lymphoma
,
lymphoma
,
hematologic diseases
,
leukemia
,
b-cell leukemia
Benzodiazepine
healthy volunteers/patients
Dabigatran
healthy volunteers/patients
,
atrial fibrillation
,
hemorrhage
,
uterine hemorrhage
,
venous thromboembolism
,
thromboembolism
,
stroke
Benzimidazole
healthy volunteers/patients
,
multiple myeloma
,
b-cell chronic lymphocytic leukemia
,
plasma cell neoplasms
,
hematologic neoplasms
,
hodgkin disease
,
leukemia
,
neoplasms
,
lymphoma
,
non-hodgkin lymphoma
,
mantle-cell lymphoma
Menatetrenone
psoriasis
,
rheumatoid arthritis
,
arthritis
,
hypersensitivity
,
ulcerative colitis
,
crohn disease
,
colitis
,
ulcer
,
alzheimer disease
,
ovarian neoplasms
,
ovarian epithelial carcinoma
,
drug interactions
,
chronic hepatitis b
,
atopic dermatitis
,
healthy volunteers/patients
,
cerebral hemorrhage
,
sickle cell anemia
,
anemia
,
pulmonary hypertension
,
knee osteoarthritis
,
stroke
,
thromboembolism
,
embolism
,
intracranial hemorrhages
,
chronic kidney failure
,
drug-related side effects and adverse reactions
,
heart valve diseases
,
neoplasms
,
hemostatic disorders
,
hypertensive intracranial hemorrhage
,
rheumatic heart disease
,
acute coronary syndrome
,
myocardial infarction
,
intracranial thrombosis
,
recurrence
,
postmenopausal osteoporosis
,
hepatitis b
,
inferior wall myocardial infarction
,
cerebrovascular disorders
,
subarachnoid hemorrhage
,
subdural hematoma
,
cerebral intraventricular hemorrhage
,
cerebral small vessel diseases
,
kidney diseases
,
internal carotid artery dissection
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
sclerosis
,
headache
,
hemorrhagic stroke
,
seizures
,
prostheses and implants
,
transient ischemic attack
,
covid-19
,
malaria
,
cardiomyopathies
,
carcinoma
,
hepatocellular carcinoma
,
liver neoplasms
,
hepatitis c
,
atrial fibrillation
,
hemorrhage
,
venous thromboembolism
,
thrombosis
,
pulmonary embolism
,
venous thrombosis
,
osteoporosis
,
ischemic stroke
,
atrial flutter
,
chronic renal insufficiency
,
heart failure
,
hematoma
,
diabetes mellitus
,
mitral valve stenosis
,
st elevation myocardial infarction
,
coronary disease
,
angina pectoris
,
stable angina
,
non-st elevated myocardial infarction
,
unstable angina
,
prediabetic state
,
vascular calcification
,
burns
,
blood coagulation disorders
,
mucocutaneous lymph node syndrome
,
coronary aneurysm
,
vitamin k deficiency
,
inflammation
,
coronary artery disease
,
gastrointestinal hemorrhage
,
metabolic bone diseases
,
renal insufficiency
,
medication adherence
,
micronutrients
,
hypertension
,
hyperhomocysteinemia
,
pharmacokinetics
,
traumatic intracranial hemorrhage
,
cardiovascular diseases
,
renal dialysis
,
hip fractures
,
bone fractures
,
home nursing
,
aging
,
atherosclerosis
,
frailty
,
hypokalemia
,
potassium deficiency
,
oxidative stress
,
hemophilia a
,
hemophilia b
,
periodontitis
,
gingivitis
,
obesity
,
overweight
,
cardiometabolic risk factors
Tirabrutinib
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
b-cell lymphoma marginal zone
,
follicular lymphoma
,
mantle-cell lymphoma
,
waldenstrom macroglobulinemia
,
b-cell lymphoma
,
interdigitating dendritic cell sarcoma
Aspartame
healthy volunteers/patients
,
colorectal neoplasms
,
chronic renal insufficiency
,
kidney diseases
,
sickle cell anemia
,
knee osteoarthritis
,
osteoarthritis
,
heart failure
,
lung neoplasms
,
ovarian neoplasms
,
sarcoma
,
ovarian epithelial carcinoma
,
head and neck neoplasms
,
squamous cell carcinoma
,
squamous cell neoplasms
,
laryngeal neoplasms
,
opioid-related disorders
,
covid-19
,
coronavirus infections
,
carcinoma
,
neoplasms
,
brain neoplasms
,
glioma
,
neurofibromatosis 2
,
acoustic neuroma
,
meningioma
,
ependymoma
,
neurofibromatosis 1
,
neurofibromatoses
,
neurofibroma
,
neurilemmoma
,
body weight
,
cystic fibrosis
,
melanoma
,
biliary tract neoplasms
,
rare diseases
,
urinary bladder neoplasms
,
invasive hydatidiform mole
,
non-muscle invasive bladder neoplasms
,
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
mantle-cell lymphoma
,
b-cell lymphoma
,
b-cell leukemia
,
diabetes mellitus
,
chronic obstructive pulmonary disease
,
obesity
,
non-small-cell lung carcinoma
,
asthma
,
pulmonary eosinophilia
,
overweight
,
weight loss
,
hyperkalemia
,
nasal polyps
,
endometrial neoplasms
,
borderline personality disorder
,
personality disorders
,
churg-strauss syndrome
,
eosinophilic granuloma
,
type 2 diabetes mellitus
,
breast neoplasms
,
fibrosis
,
inflammation
,
myocarditis
,
endomyocardial fibrosis
,
postoperative pain
,
depression
,
major depressive disorder
,
depressive disorder
,
systemic lupus erythematosus
Bevifimod
hematologic neoplasms
,
biphenotypic leukemia acute
,
b-cell leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
stomach neoplasms
,
myelodysplastic syndromes
,
stroke
,
muscle spasticity
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
endometriosis
,
infertility
,
ovarian neoplasms
,
recurrence
,
b-cell lymphoma
,
b-cell lymphoma marginal zone
,
fallopian tube neoplasms
,
burkitt lymphoma
,
multiple myeloma
,
prostatic neoplasms
,
pancreatic neoplasms
,
triple negative breast neoplasms
,
esophageal neoplasms
,
squamous cell carcinoma of head and neck
,
reactive arthritis
,
waldenstrom macroglobulinemia
,
lymphoproliferative disorders
,
lymphatic diseases
,
intestinal neoplasms
,
colonic neoplasms
,
rectal neoplasms
,
carcinoma
,
glioblastoma
,
melanoma
,
neuroendocrine carcinoma
,
papillary thyroid cancer
,
adenocarcinoma
,
primary myelofibrosis
,
splenomegaly
,
hairy cell leukemia
,
abdominal hernia
,
ventral hernia
,
breast neoplasms
,
urinary bladder neoplasms
,
uterine neoplasms
,
knee osteoarthritis
,
residual neoplasm
,
neuralgia
,
interstitial cystitis
,
neoadjuvant therapy
,
ovarian epithelial carcinoma
,
mantle-cell lymphoma
,
female genital neoplasms
,
peritoneal neoplasms
,
neoplasms
,
non-hodgkin lymphoma
,
crohn disease
,
non-small-cell lung carcinoma
,
b-cell chronic lymphocytic leukemia
,
myeloid leukemia acute
,
colorectal neoplasms
,
lymphoma
,
large b-cell lymphoma diffuse
,
follicular lymphoma
,
lung neoplasms
,
joint diseases
,
musculoskeletal diseases
,
ankylosing spondylitis
,
small cell lung carcinoma
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
inflammatory bowel diseases
,
macular degeneration
,
spondylitis
,
juvenile arthritis
,
neoplasm metastasis
,
skin diseases
,
papulosquamous skin diseases
,
wet macular degeneration
,
infections
,
communicable diseases
,
bacterial infections
,
methicillin-resistant staphylococcus aureus
,
staphylococcal skin infections
,
infectious skin diseases
,
bacterial skin diseases
,
cellulitis
,
disease progression
,
covid-19
,
parkinson disease
,
bronchopulmonary dysplasia
,
respiratory syncytial viruses
,
hepatitis b
,
ulcer
,
pyoderma gangrenosum
,
spondylarthropathies
,
spondylarthritis
,
spinal diseases
,
uveitis
,
intermediate uveitis
,
posterior uveitis
,
precocious puberty
,
migraine disorders
,
retinal diseases
,
retinal degeneration
,
eye diseases
,
choroidal neovascularization
,
leukemia
,
lymphoid leukemia
,
hepatocellular carcinoma
,
liver neoplasms
,
thyroid diseases
,
hypothyroidism
,
rheumatoid arthritis
,
psoriasis
,
arthritis
,
ulcerative colitis
,
psoriatic arthritis
,
hepatitis c
,
chronic hepatitis c
,
hidradenitis suppurativa
,
axial spondyloarthritis
,
cardiovascular diseases
,
connective tissue diseases
,
seizures
,
panuveitis
,
hiv infections
,
drug monitoring
,
coronary artery disease
,
myocardial ischemia
,
inflammation
,
atherosclerosis
Nadide
myelodysplastic syndromes
,
myeloid leukemia acute
,
recurrence
,
biphenotypic leukemia acute
,
neoplasm metastasis
,
precursor cell lymphoblastic leukemia-lymphoma
,
hepatitis
,
chronic hepatitis
,
hepatitis a
,
hepatitis c
,
chronic hepatitis c
,
hepacivirus
,
chronic hepatitis b
Retinol
hepatitis c
,
hepatitis
,
hepatitis a
Globulin, immune
urologic diseases
,
herpesviridae infections
,
viremia
,
kidney diseases
,
glomerulonephritis
,
nephrotic syndrome
,
immune system diseases
,
autoimmune diseases
,
male urogenital diseases
,
nephritis
,
female urogenital diseases
,
female urogenital diseases and pregnancy complications
,
urogenital diseases
,
iga glomerulonephritis
Digitalis
healthy volunteers/patients
,
type 2 diabetes mellitus
,
rheumatoid arthritis
,
diabetes mellitus
,
atrial fibrillation
,
pharmacokinetics
Endocrine
type 1 diabetes mellitus
Lactams
healthy volunteers/patients
Mk3475
neoplasms
,
neoplasm metastasis
,
non-small-cell lung carcinoma
,
lung neoplasms
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