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Immunogen
Immunogen
(IMGN)
ImmunoGen, Inc. (Nasdaq: IMGN) is a biotechnology company focused on the development of antibody-drug conjugate (ADC) therapeutics for the treatment of cancer. ImmunoGen was founded in 1981 and is headquartered in Waltham, Massachusetts.
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Elahere
Mirvetuximab soravtansine
2022-11-14
Fallopian tube neoplasms
,
Ovarian epithelial carcinoma
,
Peritoneal neoplasms
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Mirvetuximab soravtansine
carcinosarcoma
,
hereditary breast and ovarian cancer syndrome
,
endometrial neoplasms
,
breast neoplasms
,
triple negative breast neoplasms
,
fallopian tube diseases
,
endometrioid carcinoma
,
acinar cell carcinoma
,
neoadjuvant therapy
,
fallopian tube neoplasms
,
ovarian neoplasms
,
ovarian epithelial carcinoma
,
peritoneal neoplasms
,
neoplasms
,
neoplasm metastasis
Rucaparib
prostatic neoplasms
,
stomach neoplasms
,
ovarian neoplasms
,
peritoneal neoplasms
,
leiomyosarcoma
,
esophageal neoplasms
,
adenocarcinoma
,
endometrioid carcinoma
,
endometrial neoplasms
,
neoplasms
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
pathologic complete response
Rucaparib camsylate
prostatic neoplasms
,
stomach neoplasms
,
ovarian neoplasms
,
peritoneal neoplasms
,
leiomyosarcoma
,
esophageal neoplasms
,
adenocarcinoma
,
endometrioid carcinoma
,
endometrial neoplasms
,
neoplasms
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
pathologic complete response
Etrolizumab
bcr-abl positive chronic myelogenous leukemia
,
neoplasm metastasis
,
blast crisis
,
healthy volunteers/patients
,
castration-resistant prostatic neoplasms
,
primary myelofibrosis
,
leukemia myeloid chronic atypical bcr-abl negative
,
thrombocytosis
,
aplastic anemia
,
second primary neoplasms
,
brain neoplasms
,
glioblastoma
,
astrocytoma
,
hypertension
,
essential hypertension
,
prolymphocytic leukemia
,
prolymphocytic leukemia b-cell
,
cutaneous malignant melanoma
,
myeloid leukemia acute
,
myelodysplastic syndromes
,
non-hodgkin lymphoma
,
leukemia
,
multiple myeloma
,
hodgkin disease
,
mantle-cell lymphoma
,
b-cell lymphoma
,
myelomonocytic leukemia chronic
,
lymphoma
,
myeloid leukemia chronic-phase
,
myeloid leukemia
,
lymphoid leukemia
,
refractory anemia with excess of blasts
,
hematologic neoplasms
,
myeloproliferative disorders
,
myeloid leukemia accelerated phase
,
recurrence
,
syndrome
,
colorectal neoplasms
,
t-cell lymphoma
,
large b-cell lymphoma diffuse
,
prostatic neoplasms
,
breast neoplasms
,
pancreatic neoplasms
,
myelodysplastic-myeloproliferative diseases
,
myelomonocytic leukemia acute
,
preleukemia
,
ovarian neoplasms
,
transitional cell carcinoma
,
carcinoma
,
skin neoplasms
,
melanoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
promyelocytic leukemia acute
,
myelomonocytic leukemia juvenile
,
ovarian epithelial carcinoma
,
urologic neoplasms
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
non-small-cell lung carcinoma
,
merkel cell carcinoma
,
polyomavirus infections
,
megakaryoblastic leukemia acute
,
monocytic leukemia acute
,
erythroblastic leukemia acute
,
renal cell carcinoma
,
endometrial neoplasms
,
hepatocellular carcinoma
,
stomach neoplasms
,
head and neck neoplasms
,
thyroid neoplasms
,
esophageal neoplasms
,
lung neoplasms
,
urinary bladder neoplasms
,
glioma
,
uterine neoplasms
,
liver neoplasms
,
kidney neoplasms
,
uterine cervical neoplasms
,
colonic neoplasms
,
rectal neoplasms
,
follicular lymphoma
,
multiple sclerosis
,
hematopoietic stem cell transplantation
,
vasculitis
,
autoimmune diseases
,
nervous system diseases
,
autoimmune diseases of the nervous system
,
autologous transplantation
,
neuromyelitis optica
,
myasthenia gravis
,
ocular motility disorders
,
polyneuropathies
,
muscle weakness
,
myoclonus
,
stiff-person syndrome
,
central nervous system vasculitis
,
spinocerebellar degenerations
,
chronic inflammatory demyelinating polyradiculoneuropathy
,
lambert-eaton myasthenic syndrome
,
opsoclonus-myoclonus syndrome
,
encephalitis
,
sclerosis
,
osteosarcoma
,
blastic plasmacytoid dendritic cell neoplasm
,
type 1 diabetes mellitus
,
hematologic diseases
,
ventilator-associated pneumonia
,
fever
,
bacterial pneumonia
,
abdominal abscess
,
ileus
,
mycoses
,
large-cell lymphoma anaplastic
,
t-cell lymphoma peripheral
,
mycosis fungoides
,
cicatrix
,
wound healing
,
re-epithelialization
,
sickle cell anemia
,
beta-thalassemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
burkitt lymphoma
,
ulcerative colitis
,
colitis
,
ulcer
,
biphenotypic leukemia acute
,
precursor b-cell lymphoblastic leukemia-lymphoma
,
b-cell chronic lymphocytic leukemia
,
covid-19
,
pneumonia
,
philadelphia chromosome
,
bacterial infections
,
crohn disease
,
down syndrome
,
anemia
,
neuroblastoma
,
pyelonephritis
,
respiratory tract infections
,
respiratory tract diseases
,
lung diseases
,
human influenza
,
community-acquired pneumonia
,
central nervous system neoplasms
,
respiratory distress syndrome
,
coronavirus infections
,
severe acute respiratory syndrome
,
coronavirus
,
retinoblastoma
,
ganglioneuroblastoma
,
neoplasms
,
infections
,
urinary tract infections
,
premature obstetric labor
,
premature birth
,
premature rupture fetal membranes
,
rupture
,
spontaneous rupture
,
inflammation
,
surgical wound infection
,
neonatal sepsis
,
periodontitis
,
aggressive periodontitis
,
aggression
,
coronary artery disease
,
atrial fibrillation
,
cytokine release syndrome
,
viral pneumonia
,
snoring
,
cardiovascular diseases
,
erectile dysfunction
,
appendicitis
,
obesity
,
body weight
,
insulin resistance
,
cleft palate
,
velopharyngeal insufficiency
,
acute kidney injury
,
microbiota
,
bronchiectasis
,
motor activity
,
tooth extraction
,
chronic obstructive pulmonary disease
,
asthma
,
spirometry
,
electric impedance
,
bronchoconstriction
Doconexent
healthy volunteers/patients
,
hiv
,
b-cell chronic lymphocytic leukemia
,
obesity
,
overweight
,
immunoglobulin light-chain amyloidosis
,
syndrome
,
lymphoid leukemia
,
residual neoplasm
,
myelodysplastic syndromes
,
preleukemia
,
depression
,
treatment-resistant depressive disorder
,
depressive disorder
,
crohn disease
,
recurrence
,
poems syndrome
,
alzheimer disease
,
frailty
,
leukemia
,
neoplasms
,
precursor cell lymphoblastic leukemia-lymphoma
,
paraproteinemias
,
lymphoma
,
follicular lymphoma
,
amyloidosis
,
smoldering multiple myeloma
,
rheumatoid arthritis
,
arthritis
,
multiple myeloma
,
plasma cell neoplasms
ANETUMAB RAVTANSINE
non-small-cell lung carcinoma
,
medical sociology
,
ovarian neoplasms
,
triple negative breast neoplasms
,
cholangiocarcinoma
,
thymoma
,
renal insufficiency
,
oncogenes
,
neoplasms
,
lung neoplasms
,
pancreatic neoplasms
,
mesothelioma
,
malignant mesothelioma
,
endometrioid carcinoma
,
adenocarcinoma
,
adenocarcinoma of lung
Bevifimod
healthy volunteers/patients
,
factor vii deficiency
,
psoriasis
,
hidradenitis suppurativa
,
diffuse scleroderma
,
thrombosis
,
systemic scleroderma
,
rheumatoid arthritis
,
chronic obstructive pulmonary disease
,
soft tissue infections
,
necrotizing fasciitis
,
fournier gangrene
,
gas gangrene
,
raynaud disease
,
wounds and injuries
,
myasthenia gravis
,
cardiac surgical procedures
,
covid-19
,
eosinophilic esophagitis
,
postpartum hemorrhage
,
acute kidney injury
,
sickle cell anemia
,
acute chest syndrome
,
vaso-occlusive crises
,
hemophilia a
,
agammaglobulinemia
,
common variable immunodeficiency
,
graft vs host disease
,
hereditary angioedemas
,
afibrinogenemia
,
blood coagulation disorders
,
ischemic stroke
,
stroke
,
coronary artery disease
,
heart diseases
,
heart valve diseases
,
chronic inflammatory demyelinating polyradiculoneuropathy
,
kidney transplantation
,
igg deficiency
,
von willebrand diseases
,
hemostatic disorders
,
postoperative hemorrhage
,
dermatomyositis
,
atrial fibrillation
,
heart failure
,
hypertension
,
cardiovascular diseases
,
acute coronary syndrome
,
hemorrhagic stroke
,
peripheral arterial disease
,
atherosclerosis
,
central nervous system diseases
,
central nervous system infections
,
encephalomyelitis
,
encephalitis
,
meningoencephalitis
,
acquired immunodeficiency syndrome
,
job syndrome
,
factor xiii deficiency
,
thrombocytopenia
,
hemophilia b
,
primary immunodeficiency diseases
,
hemorrhage
,
hereditary angioedema types i and ii
,
alpha 1-antitrypsin deficiency
,
surgical blood loss
,
immunologic deficiency syndromes
,
thrombocytopenic purpura idiopathic
,
emphysema
,
cardiovascular surgical procedures
,
tropical spastic paraparesis
,
infections
,
communicable diseases
,
thromboembolism
,
sclerosis
,
sinusitis
,
pneumococcal infections
,
otitis media
,
streptococcal infections
,
bacterial pneumonia
,
meningitis
,
bacterial meningitis
,
haemophilus influenzae
,
hereditary complement deficiency diseases
,
neisseriaceae infections
,
lung diseases
,
ataxia
,
ataxia telangiectasia
,
telangiectasis
,
x-linked combined immunodeficiency diseases
,
cerebellar ataxia
CANTUZUMAB RAVTANSINE
colorectal neoplasms
,
pancreatic neoplasms
,
stomach neoplasms
LORVOTUZUMAB MERTANSINE
multiple myeloma
,
recurrence
,
ovarian neoplasms
,
merkel cell carcinoma
,
plasma cell neoplasms
,
lung neoplasms
,
small cell lung carcinoma
,
neuroblastoma
,
synovial sarcoma
,
rhabdomyosarcoma
,
neurofibrosarcoma
,
wilms tumor
,
pulmonary blastoma
,
leukemia
,
hematologic neoplasms
Lotamilast
liver failure
,
hepatic insufficiency
,
renal insufficiency
,
hypertension
,
hepatitis c
,
hepatitis
,
hepatitis a
,
neoplasms
,
overactive urinary bladder
,
parkinson disease
,
central nervous system diseases
,
brain diseases
,
movement disorders
,
neurodegenerative diseases
,
head and neck neoplasms
,
cough
,
schizophrenia
,
nervous system diseases
,
carcinoma
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
squamous cell neoplasms
,
leukemia
,
myelodysplastic syndromes
,
bcr-abl positive chronic myelogenous leukemia
,
myeloid leukemia
,
preleukemia
,
blast crisis
,
lymphoid leukemia
,
melanoma
,
colorectal neoplasms
,
non-small-cell lung carcinoma
,
esophageal neoplasms
,
panic disorder
,
alcoholism
,
postoperative pain
,
osteoarthritis
,
neuralgia
,
postherpetic neuralgia
,
general anesthesia
,
glioblastoma
,
astrocytoma
,
anesthesia
,
muscle relaxation
,
delayed emergence from anesthesia
NARATUXIMAB EMTANSINE
leukemia
,
lymphoma
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
non-hodgkin lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
Polyglycolic acid
hepatocellular carcinoma
,
liver neoplasms
,
neoplasms
,
esophageal neoplasms
,
pancreatic ductal carcinoma
,
biliary tract neoplasms
,
neoplasm metastasis
,
pancreatic neoplasms
,
lung neoplasms
,
colorectal neoplasms
,
non-small-cell lung carcinoma
,
adenocarcinoma
,
stomach neoplasms
,
esophageal squamous cell carcinoma
,
colonic neoplasms
,
rectal neoplasms
,
non-hodgkin lymphoma
,
hiv infections
,
acquired immunodeficiency syndrome
,
cardiovascular diseases
,
stroke
,
myocardial infarction
,
coronary disease
,
renal cell carcinoma
Remetinostat
healthy volunteers/patients
,
ulcerative colitis
Usistapide
postoperative pain
Globulin, immune
rheumatoid arthritis
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