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Company ReportsImmunogen

Immunogen(IMGN)

ImmunoGen, Inc. (Nasdaq: IMGN) is a biotechnology company focused on the development of antibody-drug conjugate (ADC) therapeutics for the treatment of cancer. ImmunoGen was founded in 1981 and is headquartered in Waltham, Massachusetts.

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Therapeutic Areas:

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Elahere	Mirvetuximab soravtansine	2022-11-14		Fallopian tube neoplasms , Ovarian epithelial carcinoma , Peritoneal neoplasms

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Mirvetuximab soravtansine

,

,

,

hereditary breast and ovarian cancer syndrome

,

mullerian mixed tumor

,

,

endometrial neoplasms

,

serous cystadenocarcinoma

,

endometrioid carcinoma

,

,

clear cell adenocarcinoma

,

acinar cell carcinoma

,

ovarian neoplasms

,

fallopian tube neoplasms

,

ovarian epithelial carcinoma

,

peritoneal neoplasms

,

prostatic neoplasms

,

stomach neoplasms

,

peritoneal neoplasms

,

,

esophageal neoplasms

,

,

,

endometrioid carcinoma

,

serous cystadenocarcinoma

,

endometrial neoplasms

,

fallopian tube neoplasms

,

ovarian neoplasms

,

ovarian epithelial carcinoma

Rucaparib camsylate

female genital neoplasms

,

,

breast neoplasms

,

,

endometrial neoplasms

,

triple negative breast neoplasms

,

hypersensitivity

,

hereditary breast and ovarian cancer syndrome

,

small cell lung carcinoma

,

pancreatic neoplasms

,

,

,

mullerian mixed tumor

,

uterine cervical neoplasms

,

biliary tract neoplasms

,

stomach neoplasms

,

serous cystadenocarcinoma

,

non-small-cell lung carcinoma

,

urologic neoplasms

,

,

malignant mesothelioma

,

,

dna repair-deficiency disorders

,

small cell carcinoma

,

colorectal neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

,

esophageal neoplasms

,

endometrioid carcinoma

,

squamous cell carcinoma

,

adenocarcinoma of lung

,

loss of heterozygosity

,

urinary bladder neoplasms

,

urethral neoplasms

,

transitional cell carcinoma

,

ureteral neoplasms

,

pancreatic ductal carcinoma

,

,

diabetes mellitus

,

diabetic retinopathy

,

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

fallopian tube neoplasms

,

prostatic neoplasms

,

peritoneal neoplasms

,

castration-resistant prostatic neoplasms

,

,

clear cell adenocarcinoma

,

large cell carcinoma

,

adenomyoepithelioma

,

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

healthy volunteers/patients

,

pancreatic neoplasms

,

myelodysplastic-myeloproliferative diseases

,

leukemia myeloid chronic atypical bcr-abl negative

,

,

,

cutaneous malignant melanoma

,

,

medication adherence

,

second primary neoplasms

,

ovarian epithelial carcinoma

,

,

,

multiple myeloma

,

follicular lymphoma

,

mantle-cell lymphoma

,

biphenotypic leukemia acute

,

t-cell lymphoma

,

neoplasm metastasis

,

myelomonocytic leukemia acute

,

ovarian neoplasms

,

large b-cell lymphoma diffuse

,

eyelid neoplasms

,

t-cell lymphoma peripheral

,

myeloid leukemia chronic-phase

,

,

fallopian tube neoplasms

,

medulloblastoma

,

triple negative breast neoplasms

,

,

b-cell lymphoma marginal zone

,

burkitt lymphoma

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

diabetes mellitus

,

castration-resistant prostatic neoplasms

,

,

myeloid leukemia accelerated phase

,

refractory anemia with excess of blasts

,

,

primitive neuroectodermal tumors

,

neuroectodermal tumors

,

renal cell carcinoma

,

,

brain neoplasms

,

extranodal nk-t-cell lymphoma

,

waldenstrom macroglobulinemia

,

large-cell lymphoma anaplastic

,

large-cell lymphoma immunoblastic

,

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

residual neoplasm

,

,

islet cell adenoma

,

,

nervous system neoplasms

,

primitive neuroectodermal tumors peripheral

,

,

,

oligodendroglioma

,

myeloid sarcoma

,

,

ganglioneuroblastoma

,

ovarian hyperstimulation syndrome

,

,

sezary syndrome

,

immunoblastic lymphadenopathy

,

mycosis fungoides

,

adult t-cell leukemia-lymphoma

,

intraocular lymphoma

,

t-cell lymphoma cutaneous

,

plasmablastic lymphoma

,

t-cell leukemia

,

lymphomatoid granulomatosis

,

sickle cell anemia

,

,

systemic lupus erythematosus

,

biliary tract neoplasms

,

immunologic deficiency syndromes

,

hematopoietic stem cell transplantation

,

erythroblastic leukemia acute

,

pathologic complete response

,

head and neck neoplasms

,

wounds and injuries

,

,

,

thyroid neoplasms

,

papillary thyroid cancer

,

thyroid diseases

,

follicular adenocarcinoma

,

papillary carcinoma

,

type 1 diabetes mellitus

,

urinary retention

,

,

urinary tract infections

,

pelvic organ prolapse

,

male breast neoplasms

,

pulmonary alveolar proteinosis

,

hematologic diseases

,

clostridium infections

,

bone marrow transplantation

,

,

basal cell carcinoma

,

merkel cell carcinoma

,

basal cell neoplasms

,

hypersensitivity

,

graft vs host disease

,

prolymphocytic leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

,

,

non-hodgkin lymphoma

,

myeloproliferative disorders

,

philadelphia chromosome

,

hematologic neoplasms

,

bcr-abl positive chronic myelogenous leukemia

,

hodgkin disease

,

non-small-cell lung carcinoma

,

geographic atrophy

,

,

breast neoplasms

,

plasma cell neoplasms

,

b-cell lymphoma

,

prostatic neoplasms

,

b-cell chronic lymphocytic leukemia

,

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

rhabdomyosarcoma

,

primary myelofibrosis

,

central nervous system neoplasms

,

,

mucocutaneous lymph node syndrome

,

,

,

,

,

macular degeneration

,

,

spinal cord neoplasms

,

,

neuroendocrine tumors

,

muscle spasticity

,

colorectal neoplasms

,

induction chemotherapy

,

venous thromboembolism

,

thromboembolism

,

,

,

,

ischemic stroke

,

,

,

brain stem neoplasms

,

,

invasive hydatidiform mole

,

,

nephrotic syndrome

,

,

pulmonary embolism

,

,

autonomic nervous system diseases

,

,

primary dysautonomias

,

familial dysautonomia

,

hydatidiform mole

,

gestational trophoblastic disease

,

choriocarcinoma

,

trophoblastic neoplasms

,

juvenile arthritis

,

kidney neoplasms

,

,

,

myeloid leukemia acute

,

myeloid leukemia

,

myelodysplastic syndromes

,

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

,

,

rheumatoid arthritis

,

,

,

aplastic anemia

,

,

inflammatory bowel diseases

,

ulcerative colitis

,

,

,

kidney diseases

,

,

iga glomerulonephritis

,

child mortality

,

growth and development

,

critical illness

,

premature birth

,

intestinal diseases

,

lupus nephritis

,

,

kidney transplantation

,

,

plantar fasciitis

,

,

,

,

,

acute coronary syndrome

,

coronary artery disease

,

percutaneous coronary intervention

,

,

gastrointestinal diseases

,

cardiovascular diseases

,

gastrointestinal stromal tumors

,

,

esophageal neoplasms

,

,

chronic hepatitis b

,

,

chronic hepatitis

,

,

thrombocytopenia

,

germ cell and embryonal neoplasms

,

,

retinal neoplasms

,

phenylketonurias

,

heart disease risk factors

,

stomatognathic diseases

,

endocrine system diseases

,

autoimmune diseases

,

cognitive dysfunction

,

neurocognitive disorders

,

major depressive disorder

,

depressive disorder

,

,

type 2 diabetes mellitus

,

chronic periodontitis

,

,

,

,

equinus deformity

,

,

,

,

drug-related side effects and adverse reactions

,

digestive system diseases

,

,

wasting syndrome

,

child nutrition disorders

,

,

severe acute malnutrition

,

hypertrophic cardiomyopathy

,

ventricular tachycardia

,

cardiomyopathies

,

cardiac arrhythmias

,

dilated cardiomyopathy

,

,

,

ventricular fibrillation

,

mitral valve prolapse

,

restrictive cardiomyopathy

neoplasm metastasis

,

primary myelofibrosis

,

,

adrenal gland neoplasms

,

pharmacokinetics

,

depressive disorder

,

castration-resistant prostatic neoplasms

,

leukemia myeloid chronic atypical bcr-abl negative

,

,

,

pure autonomic failure

,

,

,

mandibular fractures

,

skin abnormalities

,

endometrioid carcinoma

,

serous cystadenocarcinoma

,

clear cell adenocarcinoma

,

,

acinar cell carcinoma

,

relapsing-remitting multiple sclerosis

,

,

second primary neoplasms

,

brain neoplasms

,

,

,

major depressive disorder

,

cocaine-related disorders

,

,

essential hypertension

,

prolymphocytic leukemia

,

prolymphocytic leukemia b-cell

,

,

frontotemporal dementia

,

primary progressive aphasia

,

pick disease of the brain

,

,

multiple myeloma

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia juvenile

,

hematologic neoplasms

,

myelomonocytic leukemia chronic

,

plasma cell neoplasms

,

mantle-cell lymphoma

,

,

refractory anemia with excess of blasts

,

myeloid leukemia chronic-phase

,

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia accelerated phase

,

myelomonocytic leukemia acute

,

diabetes mellitus

,

biphenotypic leukemia acute

,

cutaneous malignant melanoma

,

beta-thalassemia

,

,

prostatic neoplasms

,

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

colorectal neoplasms

,

,

type 1 diabetes mellitus

,

t-cell lymphoma

,

follicular lymphoma

,

postoperative pain

,

burkitt lymphoma

,

hematopoietic stem cell transplantation

,

replacement arthroplasty knee

,

blastic plasmacytoid dendritic cell neoplasm

,

,

graft vs host disease

,

breast neoplasms

,

pancreatic neoplasms

,

transitional cell carcinoma

,

metabolic syndrome

,

,

bronchiolitis obliterans syndrome

,

monocytic leukemia acute

,

megakaryoblastic leukemia acute

,

erythroblastic leukemia acute

,

endometrial neoplasms

,

cardiovascular diseases

,

aplastic anemia

,

pathologic complete response

,

nervous system diseases

,

congenital abnormalities

,

sickle cell anemia

,

,

,

urologic neoplasms

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

non-small-cell lung carcinoma

,

merkel cell carcinoma

,

polyomavirus infections

,

glucose metabolism disorders

,

metabolic diseases

,

,

endocrine system diseases

,

bronchiolitis obliterans

,

interstitial lung diseases

,

cryptogenic organizing pneumonia

,

organizing pneumonia

,

basophilic leukemia acute

,

renal cell carcinoma

,

hepatocellular carcinoma

,

stomach neoplasms

,

head and neck neoplasms

,

thyroid neoplasms

,

esophageal neoplasms

,

urinary bladder neoplasms

,

,

uterine neoplasms

,

liver neoplasms

,

kidney neoplasms

,

uterine cervical neoplasms

,

colonic neoplasms

,

rectal neoplasms

,

thyroid diseases

,

bacterial endocarditis

,

,

subacute bacterial endocarditis

,

,

autoimmune diseases

,

autoimmune diseases of the nervous system

,

autologous transplantation

,

neuromyelitis optica

,

myasthenia gravis

,

ocular motility disorders

,

polyneuropathies

,

muscle weakness

,

,

stiff-person syndrome

,

central nervous system vasculitis

,

spinocerebellar degenerations

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

lambert-eaton myasthenic syndrome

,

opsoclonus-myoclonus syndrome

,

,

,

orthostatic intolerance

,

b-cell lymphoma marginal zone

,

mast-cell leukemia

,

lymphoproliferative disorders

,

,

nervous system neoplasms

,

waldenstrom macroglobulinemia

,

,

bone marrow failure disorders

,

,

dyskeratosis congenita

,

stem cell transplantation

,

hematologic diseases

,

myeloid sarcoma

,

,

,

pituitary acth hypersecretion

,

cushing syndrome

,

acth-secreting pituitary adenoma

,

obstructive sleep apnea

,

sleep apnea syndromes

,

,

postural orthostatic tachycardia syndrome

,

cavernous hemangioma central nervous system

,

craniocerebral trauma

,

,

nervous system trauma

,

,

pulmonary tuberculosis

,

refractory anemia

,

,

large-cell lymphoma anaplastic

,

t-cell lymphoma peripheral

,

mycosis fungoides

,

bronchial spasm

,

alcohol drinking

,

re-epithelialization

,

local anesthesia

,

chlamydia infections

,

ischemic stroke

,

cerebrovascular disorders

,

central nervous system diseases

,

,

,

pulmonary edema

,

low tension glaucoma

,

inborn genetic diseases

,

,

,

myeloid leukemia acute

,

myeloid leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

myelodysplastic syndromes

,

,

,

non-hodgkin lymphoma

,

,

myeloproliferative disorders

,

hodgkin disease

,

ulcerative colitis

,

,

philadelphia chromosome

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

bacterial pneumonia

,

multiple sclerosis

,

,

b-cell chronic lymphocytic leukemia

,

b-cell lymphoma

,

,

,

large b-cell lymphoma diffuse

,

ventilator-associated pneumonia

,

,

,

port-wine stain

,

capillary hemangioma

,

promyelocytic leukemia acute

,

,

healthcare-associated pneumonia

,

central nervous system neoplasms

,

eyelid neoplasms

,

,

,

,

severe acute malnutrition

,

,

,

,

gata2 deficiency

,

,

iatrogenic disease

,

acinetobacter infections

,

hypersensitivity

,

,

,

enterobacteriaceae infections

,

gram-negative bacterial infections

,

,

wounds and injuries

,

traumatic brain injuries

,

,

,

coronavirus infections

,

severe acute respiratory syndrome

,

,

,

environmental biomarkers

,

community-acquired pneumonia

,

community-acquired infections

,

microbial drug resistance

,

methicillin-resistant staphylococcus aureus

,

,

,

,

intraabdominal infections

,

wound infection

,

respiratory aspiration

,

,

staphylococcal skin infections

,

infectious skin diseases

,

bacterial skin diseases

,

,

,

,

,

,

,

,

tobacco use disorder

,

smoking cessation

,

,

,

suppurative otitis media

,

,

child nutrition disorders

,

critical illness

,

intracranial hemorrhages

,

cerebral hemorrhage

,

hemorrhagic stroke

,

,

,

gouty arthritis

,

,

ganglioneuroblastoma

,

intracranial pressure

,

,

,

,

,

communicable diseases

,

healthy volunteers/patients

,

chronic obstructive pulmonary disease

,

atrial fibrillation

,

obstructive lung diseases

,

urinary tract infections

,

,

,

bacterial infections

,

,

,

,

,

,

,

,

respiratory tract infections

,

,

,

,

type 2 diabetes mellitus

,

,

,

,

staphylococcal infections

,

liver cirrhosis

,

,

,

,

respiratory distress syndrome

,

,

,

ocular hypertension

,

open-angle glaucoma

,

infectious arthritis

,

,

respiratory sounds

,

tooth extraction

,

coronary artery disease

,

,

angina pectoris

,

,

cardiomyopathies

,

dilated cardiomyopathy

,

diabetic nephropathies

,

kidney diseases

,

,

,

,

pyogenic liver abscess

,

gastrointestinal hemorrhage

,

esophageal and gastric varices

,

pituitary neoplasms

,

,

pituitary diseases

,

dental focal infection

,

focal infection

,

respiratory insufficiency

,

,

,

chronic bronchitis

,

airway obstruction

,

disease progression

,

essential tremor

,

,

heart septal defects

,

ventricular heart septal defects

,

cardiac surgical procedures

,

neonatal sepsis

,

,

,

,

venous thrombosis

,

pulmonary embolism

,

,

vascular diseases

,

bronchopulmonary dysplasia

,

,

,

,

,

postoperative cognitive complications

,

cognitive dysfunction

,

acute lung injury

,

newborn respiratory distress syndrome

,

,

,

myocardial ischemia

,

,

,

premature birth

,

premature rupture fetal membranes

,

,

high-risk pregnancy

,

carpal tunnel syndrome

,

,

adrenocortical adenoma

,

cytokine release syndrome

,

viral pneumonia

,

,

,

erectile dysfunction

,

drug monitoring

,

,

bipolar disorder

,

polycystic ovary syndrome

,

peritonsillar abscess

,

spinal anesthesia

,

gestational trophoblastic disease

,

choriocarcinoma

,

trophoblastic neoplasms

,

invasive hydatidiform mole

,

,

protein-energy malnutrition

,

,

,

acute kidney injury

,

,

,

long qt syndrome

,

romano-ward syndrome

,

,

,

,

,

fallopian tube neoplasms

,

,

,

,

,

ventricular tachycardia

,

aortic dissection

,

thoracic surgical procedures

multiple myeloma

,

plasma cell neoplasms

,

aplastic anemia

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

hematologic neoplasms

,

myeloproliferative disorders

,

primary myelofibrosis

,

,

graft vs host disease

,

precursor cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia chronic

,

prolymphocytic leukemia

,

myeloid leukemia

,

myelomonocytic leukemia juvenile

,

lymphoid leukemia

ANETUMAB RAVTANSINE

medical sociology

,

non-small-cell lung carcinoma

,

ovarian neoplasms

,

renal insufficiency

,

,

,

,

,

,

pancreatic neoplasms

,

malignant mesothelioma

,

,

endometrioid carcinoma

,

serous cystadenocarcinoma

,

adenocarcinoma of lung

,

CANTUZUMAB RAVTANSINE

colorectal neoplasms

,

pancreatic neoplasms

,

stomach neoplasms

LORVOTUZUMAB MERTANSINE

multiple myeloma

,

plasma cell neoplasms

,

ovarian neoplasms

,

merkel cell carcinoma

,

,

small cell lung carcinoma

,

,

,

,

,

synovial sarcoma

,

rhabdomyosarcoma

,

neurofibrosarcoma

,

,

nerve sheath neoplasms

,

pulmonary blastoma

,

,

hematologic neoplasms

parkinson disease

,

central nervous system diseases

,

,

nervous system diseases

,

movement disorders

,

neurodegenerative diseases

,

,

,

colorectal neoplasms

,

,

non-small-cell lung carcinoma

,

head and neck neoplasms

,

esophageal neoplasms

,

,

NARATUXIMAB EMTANSINE

,

non-hodgkin lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

Polyglycolic acid

uterine cervical neoplasms

,

pancreatic ductal carcinoma

,

,

non-hodgkin lymphoma

,

hepatocellular carcinoma

,

healthy volunteers/patients

,

,

,

,

sezary syndrome

,

mycosis fungoides

,

central nervous system neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

breast neoplasms

,

ovarian neoplasms

,

,

stomach neoplasms

,

endometrial neoplasms

,

prostatic neoplasms

,

peritoneal neoplasms

,

small cell carcinoma

,

uterine neoplasms

,

esophageal neoplasms

,

,

renal cell carcinoma

,

,

female genital neoplasms

,

urologic neoplasms

,

rectal neoplasms

,

liver neoplasms

,

transitional cell carcinoma

,

,

triple negative breast neoplasms

,

,

medulloblastoma

,

,

,

rhabdomyosarcoma

,

primitive neuroectodermal tumors peripheral

,

urogenital neoplasms

,

neoplasms by site

,

cervical intraepithelial neoplasia

,

uterine cervical dysplasia

,

hydatidiform mole

,

choriocarcinoma

,

trophoblastic neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

male breast neoplasms

,

ductal carcinoma

,

pleural neoplasms

,

biliary tract neoplasms

,

bullous pemphigoid

,

,

benign mucous membrane pemphigoid

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

adenocarcinoma of lung

,

bronchiolo-alveolar adenocarcinoma

,

extranodal nk-t-cell lymphoma

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

,

ovarian epithelial carcinoma

,

,

colorectal neoplasms

,

pancreatic neoplasms

,

,

neoplasm metastasis

,

head and neck neoplasms

,

malignant mesothelioma

,

small cell lung carcinoma

,

rheumatoid arthritis

,

,

,

,

non-small-cell lung carcinoma

,

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