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Trade Name
Drug Name
Approved
Patent Expires
Indication
Vonjo
Pacritinib
2022-02-28
2028-2030
Primary myelofibrosis
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Pacritinib
healthy volunteers/patients
,
drug interactions
,
myeloid leukemia acute
,
myeloid leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
myelomonocytic leukemia chronic
,
myelomonocytic leukemia acute
,
leukemia myeloid chronic atypical bcr-abl negative
,
myelomonocytic leukemia juvenile
,
syndrome
,
renal insufficiency
,
liver diseases
,
hepatic insufficiency
,
leukemia
,
myelodysplastic syndromes
,
preleukemia
,
neoplasms
,
myeloproliferative disorders
,
graft vs host disease
,
covid-19
,
colorectal neoplasms
,
primary myelofibrosis
,
polycythemia vera
,
essential thrombocythemia
,
thrombocytosis
,
polycythemia
,
thrombocytopenia
Tartrate
healthy volunteers/patients
,
overactive urinary bladder
,
urinary incontinence
,
enuresis
,
memory
,
cognition
,
urinary bladder neck obstruction
Albumin
renal cell carcinoma
,
colorectal neoplasms
,
non-small-cell lung carcinoma
,
melanoma
,
lymphoma
,
neoplasms
,
prostatic neoplasms
,
carcinoma
,
ovarian neoplasms
,
pancreatic neoplasms
,
aggression
,
inflammatory breast neoplasms
,
lung neoplasms
,
sarcoma
,
ovarian epithelial carcinoma
,
breast neoplasms
,
type 2 diabetes mellitus
,
diabetes mellitus
,
hyperglycemia
Cilmostim
recurrence
,
multiple myeloma
,
plasma cell neoplasms
,
neoplasms
,
leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
Aglatimagene besadenovec
lymphoma
,
triple negative breast neoplasms
,
pharmacokinetics
,
healthy volunteers/patients
,
pharmacological phenomena
,
neoplasms
,
breast neoplasms
,
adenocarcinoma
,
neoplasm metastasis
,
carcinoma
,
ovarian neoplasms
,
non-small-cell lung carcinoma
,
pancreatic neoplasms
,
colorectal neoplasms
,
lung neoplasms
,
uterine cervical neoplasms
,
endometrial neoplasms
,
stomach neoplasms
,
urinary bladder neoplasms
,
small cell lung carcinoma
,
biliary tract neoplasms
,
bone neoplasms
,
bone diseases
,
hereditary breast and ovarian cancer syndrome
,
aggression
,
head and neck neoplasms
,
dna repair-deficiency disorders
,
sarcoma
,
ovarian epithelial carcinoma
,
recurrence
,
hypersensitivity
,
gynecomastia
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
heart failure
,
coronary disease
,
coronary artery disease
,
myocardial ischemia
,
heart diseases
,
osteoporosis
,
obesity
,
disease susceptibility
,
hepatocellular carcinoma
,
liver neoplasms
Glutamic acid
diabetes mellitus
,
type 1 diabetes mellitus
,
healthy volunteers/patients
,
schizophrenia
,
atrial fibrillation
Lornoxicam
b-cell lymphoma
,
inflammatory breast neoplasms
,
immunoglobulin light-chain amyloidosis
,
amyloidosis
,
myeloproliferative disorders
,
primary myelofibrosis
,
promyelocytic leukemia acute
,
myelomonocytic leukemia chronic
,
myelomonocytic leukemia acute
,
myelomonocytic leukemia juvenile
,
acute disease
,
systemic scleroderma
,
diffuse scleroderma
,
sclerosis
,
large b-cell lymphoma diffuse
,
leukemia
,
myeloid leukemia acute
,
precursor cell lymphoblastic leukemia-lymphoma
,
myeloid leukemia
,
lymphoid leukemia
,
non-hodgkin lymphoma
,
lymphoma
,
myelodysplastic syndromes
,
multiple myeloma
,
plasma cell neoplasms
,
preleukemia
,
bcr-abl positive chronic myelogenous leukemia
,
neoplasms
,
b-cell chronic lymphocytic leukemia
,
triple negative breast neoplasms
,
renal insufficiency
,
hematologic diseases
,
blood protein disorders
,
neoplasms by histologic type
,
paraproteinemias
,
hodgkin disease
,
diabetes mellitus
,
type 1 diabetes mellitus
,
prolymphocytic leukemia t-cell
,
prolymphocytic leukemia
,
recurrence
,
burkitt lymphoma
,
graft vs host disease
,
bronchiolitis obliterans syndrome
,
anemia
,
aplastic anemia
,
breast neoplasms
,
brain stem neoplasms
,
glycogen storage disease type ii
,
glycogen storage disease type iii
,
glycogen storage disease
,
ovarian neoplasms
,
hematologic neoplasms
Pixantrone
neoplasms
,
b-cell chronic lymphocytic leukemia
,
second primary neoplasms
,
neoplasm metastasis
,
breast neoplasms
,
myeloid leukemia acute
,
myeloid leukemia
,
lymphoma
,
non-hodgkin lymphoma
,
follicular lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
aggression
,
leukemia
Sodium ascorbate
bacterial infections
,
respiratory tract infections
,
infections
,
iron-deficiency anemia
,
hematopoiesis
,
iron deficiencies
,
human influenza
,
common cold
,
inflammation
,
vascular stiffness
Aspartame
tuberculosis
,
neoplasms
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
deficiency diseases
,
paraproteinemias
,
hiv infections
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
breast neoplasms
,
immune system diseases
,
hematologic neoplasms
,
type 2 diabetes mellitus
,
uveitis
,
metabolic diseases
,
disease
,
lipidoses
,
immunoglobulin g4-related disease
,
malaria
,
falciparum malaria
,
whooping cough
,
tetanus
,
diphtheria
,
tetany
,
polycystic kidney diseases
,
autosomal dominant polycystic kidney
,
arthrogryposis
,
renal insufficiency
,
hematologic diseases
,
blood protein disorders
,
neoplasms by histologic type
,
prostatic neoplasms
,
circulating neoplastic cells
,
heart transplantation
,
non-small-cell lung carcinoma
,
lung neoplasms
,
carcinoma
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
esophageal neoplasms
,
adenocarcinoma
,
neoplasm metastasis
,
anemia
,
aplastic anemia
,
multiple myeloma
,
plasma cell neoplasms
,
hypercholesterolemia
,
hyperlipoproteinemia type ii
,
meningococcal infections
,
hemolytic anemia autoimmune
,
meningitis
,
meningococcal meningitis
,
stomach neoplasms
,
hemophilia a
,
kidney diseases
,
gaucher disease
,
smoldering multiple myeloma
,
hemophilia b
,
chronic renal insufficiency
,
hyperphosphatemia
,
multiple sclerosis
,
sclerosis
,
homozygous familial hypercholesterolemia
,
pharyngitis
,
tonsillitis
,
healthy volunteers/patients
,
asthma
,
glycogen storage disease type ii
,
glycogen storage disease
,
atopic dermatitis
,
dermatitis
,
lymphoma
,
eczema
,
diabetes mellitus
,
hyperglycemia
,
glycogen storage disease type iii
,
non-hodgkin lymphoma
,
osteoporosis
,
postmenopausal osteoporosis
,
lymphoproliferative disorders
Bevifimod
healthy volunteers/patients
,
hepatic insufficiency
,
ovarian epithelial carcinoma
,
castration-resistant prostatic neoplasms
,
myeloid leukemia acute
,
myeloid leukemia
,
liver failure
,
uveal neoplasms
,
uveal melanoma
,
liver diseases
,
huntington disease
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
hiv seropositivity
,
sarcoma
,
central nervous system neoplasms
,
mantle-cell lymphoma
,
non-hodgkin lymphoma
,
uterine cervical neoplasms
,
plasma cell neoplasms
,
salivary gland neoplasms
,
cholangiocarcinoma
,
neuroendocrine tumors
,
hepatitis b
,
chronic hepatitis b
,
hepatitis
,
hepatitis a
,
unknown primary neoplasms
,
lobular carcinoma
,
invasive hydatidiform mole
,
ischemia
,
coronary artery disease
,
myocardial ischemia
,
gastrointestinal neoplasms
,
respiratory tract diseases
,
digestive system neoplasms
,
gastrointestinal diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
thoracic neoplasms
,
intestinal neoplasms
,
digestive system diseases
,
colonic diseases
,
intestinal diseases
,
bronchial neoplasms
,
waldenstrom macroglobulinemia
,
follicular lymphoma
,
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
exanthema
,
uterine neoplasms
,
female genital neoplasms
,
bronchiolo-alveolar adenocarcinoma
,
glioblastoma
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
neoplasms
,
breast neoplasms
,
carcinoma
,
colorectal neoplasms
,
triple negative breast neoplasms
,
lymphoma
,
hepatocellular carcinoma
,
liver neoplasms
,
renal cell carcinoma
,
leukemia
,
ovarian neoplasms
,
neoplasm metastasis
,
brain neoplasms
,
b-cell chronic lymphocytic leukemia
,
head and neck neoplasms
,
lymphoid leukemia
,
hematologic neoplasms
,
prostatic neoplasms
,
multiple myeloma
,
thyroid neoplasms
,
papillary thyroid cancer
,
large-cell lymphoma anaplastic
,
neoplasms by site
,
glioma
,
thyroid diseases
,
lymphoproliferative disorders
,
neoplasms by histologic type
,
malignant mesothelioma
,
mesothelioma
,
neuroblastoma
,
anaplastic thyroid carcinoma
,
laryngeal neoplasms
,
erdheim-chester disease
,
mucinous adenocarcinoma
,
ductal carcinoma breast
,
inflammatory breast neoplasms
,
kidney transplantation
,
bcr-abl positive chronic myelogenous leukemia
,
non-small-cell lung carcinoma
,
lung neoplasms
,
melanoma
,
hiv infections
,
pancreatic neoplasms
,
infections
,
communicable diseases
,
adenocarcinoma
,
acquired immunodeficiency syndrome
,
disease progression
,
adenocarcinoma of lung
,
kidney diseases
,
polyomavirus infections
,
liver cirrhosis
,
cardiotoxicity
,
fibrosis
,
hemorrhage
,
endometrial neoplasms
,
uterine hemorrhage
,
postmenopause
,
hiv-1
,
alzheimer disease
,
frontotemporal dementia
,
progressive supranuclear palsy
,
primary progressive aphasia
,
pick disease of the brain
,
hodgkin disease
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
Corticorelin
neuralgia
,
overactive urinary bladder
,
diabetic neuropathies
,
endometriosis
,
chronic cough
,
chronic renal insufficiency
,
renal insufficiency
,
healthy volunteers/patients
,
kidney diseases
,
chronic kidney failure
,
renal dialysis
,
thromboembolism
,
hemodiafiltration
,
hyperphosphatemia
,
colorectal neoplasms
Nepidermin
squamous cell carcinoma of head and neck
,
primary myelofibrosis
,
healthy volunteers/patients
,
uterine cervical neoplasms
,
cholangiocarcinoma
,
folliculitis
,
glioma
,
central nervous system neoplasms
,
nervous system neoplasms
,
colorectal neoplasms
,
lymphoma
,
carcinoma
,
stomach neoplasms
,
b-cell lymphoma
,
triple negative breast neoplasms
,
large b-cell lymphoma diffuse
,
neoplasms
,
ovarian neoplasms
,
leukemia
,
hepatocellular carcinoma
,
liver neoplasms
,
recurrence
,
melanoma
,
non-hodgkin lymphoma
,
ulcerative colitis
,
colitis
,
ulcer
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
small cell lung carcinoma
,
ovarian epithelial carcinoma
,
neoplasm metastasis
,
hemophilia a
,
macular edema
,
edema
,
syndrome
,
peritoneal neoplasms
,
lupus nephritis
,
nephritis
,
sclerosis
,
ductal carcinoma breast
,
macular degeneration
,
urinary bladder neoplasms
,
renal cell carcinoma
,
fallopian tube neoplasms
,
glioblastoma
,
head and neck neoplasms
,
asthma
,
mucinous adenocarcinoma
,
inflammatory breast neoplasms
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
pancreatic neoplasms
,
hemolysis
,
squamous cell carcinoma
,
urologic neoplasms
,
prostatic neoplasms
,
transitional cell carcinoma
,
colonic neoplasms
,
multiple sclerosis
,
nasal polyps
,
polyps
,
rhinosinusitis
,
wet macular degeneration
,
follicular lymphoma
,
systemic scleroderma
,
diffuse scleroderma
,
retinal vein occlusion
,
crohn disease
,
schizophrenia
,
hemolytic-uremic syndrome
,
atypical hemolytic uremic syndrome
,
azotemia
,
fibrosis
,
idiopathic pulmonary fibrosis
,
pulmonary fibrosis
,
autistic disorder
,
autism spectrum disorder
,
pervasive child development disorders
,
geographic atrophy
,
atrophy
,
systemic lupus erythematosus
,
nephrotic syndrome
,
nephrosis
,
lipoid nephrosis
,
esophageal squamous cell carcinoma
,
esophageal neoplasms
,
castration-resistant prostatic neoplasms
,
retinal diseases
,
diabetic retinopathy
,
thyroid neoplasms
,
neuroendocrine carcinoma
,
papillary thyroid cancer
,
thyroid diseases
,
disease progression
,
endometrioid carcinoma
,
arteritis
,
giant cell arteritis
,
polymyalgia rheumatica
,
type 2 diabetes mellitus
,
diabetes mellitus
,
kidney diseases
,
membranous glomerulonephritis
,
chronic progressive multiple sclerosis
,
sinusitis
,
ankylosing spondylitis
,
spondylarthritis
,
spondylitis
,
residual neoplasm
,
myeloid leukemia acute
,
myeloid leukemia
,
alzheimer disease
,
coronary disease
,
acute coronary syndrome
,
coronary artery disease
,
myocardial ischemia
,
heart diseases
,
relapsing-remitting multiple sclerosis
,
guillain-barre syndrome
,
autoimmune diseases of the nervous system
,
hashimoto disease
,
encephalitis
,
partial epilepsies
,
bcr-abl positive chronic myelogenous leukemia
,
disability evaluation
,
cognition disorders
,
cytomegalovirus infections
,
anemia
,
hemolytic anemia autoimmune
,
hemolytic anemia
,
mantle-cell lymphoma
,
skin diseases
,
neoplasms by site
,
breast diseases
,
endometrial neoplasms
,
covid-19
,
graft rejection
,
choroidal neovascularization
,
myopia
,
retinal neovascularization
,
pathologic neovascularization
,
human influenza
,
breast neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
adenocarcinoma
,
adenocarcinoma of lung
,
osteoporosis
,
postmenopausal osteoporosis
Palifosfamide
neoplasm metastasis
,
sarcoma
Polyglycolic acid
rectal neoplasms
,
esophageal neoplasms
,
pancreatic neoplasms
,
disease progression
,
lymphoma
,
neoplasm metastasis
,
kidney diseases
,
kidney transplantation
,
lung neoplasms
,
neoplasms
,
stomach neoplasms
,
colonic neoplasms
,
malignant mesothelioma
,
mesothelioma
,
arteritis
,
giant cell arteritis
,
polymyalgia rheumatica
,
juvenile arthritis
,
carcinoma
,
head and neck neoplasms
,
respiratory tract diseases
,
germ cell and embryonal neoplasms
,
small cell lung carcinoma
,
lung diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
thoracic neoplasms
,
bronchial diseases
,
neoplasms by histologic type
,
neoplasms by site
,
nerve tissue neoplasms
,
systemic lupus erythematosus
,
arthritis
,
rheumatoid arthritis
,
non-small-cell lung carcinoma
,
colorectal neoplasms
,
adenocarcinoma
,
adenocarcinoma of lung
,
bronchitis
,
acute disease
,
graft vs host disease
,
hematopoietic stem cell transplantation
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