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Trade Name	Drug Name	Approved	Patent Expires	Indication
Benznidazole	Benznidazole	2017-08-29		Chagas disease , Bacterial infections , Protozoan infections
Estradiol	Estradiol	2022-08-10	2024-2037	Prostatic neoplasms , Breast neoplasms , Menorrhagia , Contraception , Primary ovarian insufficiency , Hot flashes , Hypogonadism , Premature menopause , Acne vulgaris , Leiomyoma , Endometriosis , Endometrial hyperplasia , Uterine hemorrhage , Amenorrhea , Female infertility , Delayed puberty , Renal cell carcinoma , Endometrial neoplasms , Hypoventilation , Abdominal pain
Nuvessa	Metronidazole	2014-03-24	2024-2039	Rosacea , Bacterial infections , Giardiasis , Helicobacter infections , Surgical wound infection , Abscess , Bacterial vaginosis , Bacterial endocarditis , Bacterial meningitis , Protozoan infections , Amebiasis , Pseudomembranous enterocolitis , Trichomonas vaginitis , Bacteroides infections , Acne vulgaris , Nausea , Virus diseases , Diarrhea , Gonorrhea , Cholera , Escherichia coli infections , Campylobacter infections , Bacillary dysentery , Chlamydia infections , Bronchitis , Streptococcal infections , Dyspepsia , Bartonella infections , Bacterial eye infections , Syphilis , Staphylococcal infections , Stomach diseases , Borrelia infections , Rickettsia infections , Mycoplasma infections , Chancroid , Granuloma inguinale , Psittacosis

Clinical Trials

Therapeutic Areas:

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Classification:

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Approval:

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Status:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

tissue adhesions

,

healthy volunteers/patients

,

,

,

atrophic vaginitis

,

Estradiol benzoate

healthy volunteers/patients

,

,

,

,

,

,

,

Estradiol valerate

,

atrophic vaginitis

muscular atrophy

,

spinal muscular atrophy

,

,

myocardial infarction

,

wounds and injuries

,

,

,

,

coronary occlusion

,

ventricular tachycardia

,

,

,

hematologic neoplasms

,

biphenotypic leukemia acute

,

b-cell leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

stomach neoplasms

,

,

muscle spasticity

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

,

,

b-cell lymphoma

,

,

ovarian neoplasms

,

b-cell lymphoma marginal zone

,

fallopian tube neoplasms

,

multiple myeloma

,

prostatic neoplasms

,

pancreatic neoplasms

,

burkitt lymphoma

,

triple negative breast neoplasms

,

esophageal neoplasms

,

squamous cell carcinoma of head and neck

,

reactive arthritis

,

waldenstrom macroglobulinemia

,

lymphoproliferative disorders

,

lymphatic diseases

,

intestinal neoplasms

,

colonic neoplasms

,

rectal neoplasms

,

,

,

,

neuroendocrine carcinoma

,

papillary thyroid cancer

,

,

primary myelofibrosis

,

hairy cell leukemia

,

abdominal hernia

,

,

myelodysplastic syndromes

,

breast neoplasms

,

urinary bladder neoplasms

,

uterine neoplasms

,

myeloid leukemia

,

knee osteoarthritis

,

residual neoplasm

,

,

interstitial cystitis

,

neoadjuvant therapy

,

ovarian epithelial carcinoma

,

mantle-cell lymphoma

,

female genital neoplasms

,

peritoneal neoplasms

,

,

non-hodgkin lymphoma

,

,

non-small-cell lung carcinoma

,

b-cell chronic lymphocytic leukemia

,

,

myeloid leukemia acute

,

colorectal neoplasms

,

large b-cell lymphoma diffuse

,

follicular lymphoma

,

,

,

musculoskeletal diseases

,

ankylosing spondylitis

,

small cell lung carcinoma

,

neoplasm metastasis

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

inflammatory bowel diseases

,

macular degeneration

,

,

lymphoid leukemia

,

,

juvenile arthritis

,

,

papulosquamous skin diseases

,

wet macular degeneration

,

,

communicable diseases

,

bacterial infections

,

methicillin-resistant staphylococcus aureus

,

staphylococcal skin infections

,

infectious skin diseases

,

bacterial skin diseases

,

,

disease progression

,

,

parkinson disease

,

bronchopulmonary dysplasia

,

respiratory syncytial viruses

,

,

,

pyoderma gangrenosum

,

spondylarthropathies

,

spondylarthritis

,

spinal diseases

,

,

intermediate uveitis

,

posterior uveitis

,

precocious puberty

,

migraine disorders

,

retinal diseases

,

retinal degeneration

,

,

choroidal neovascularization

,

hepatocellular carcinoma

,

liver neoplasms

,

thyroid diseases

,

,

rheumatoid arthritis

,

,

,

ulcerative colitis

,

psoriatic arthritis

,

,

chronic hepatitis c

,

hidradenitis suppurativa

,

axial spondyloarthritis

,

cardiovascular diseases

,

connective tissue diseases

,

,

,

,

drug monitoring

,

coronary artery disease

,

myocardial ischemia

,

,

atherosclerosis

healthy volunteers/patients

,

,

pheochromocytoma

,

neuroendocrine tumors

,

,

meningeal carcinomatosis

,

,

laryngeal neoplasms

,

pancreatic ductal carcinoma

,

,

head and neck neoplasms

,

squamous cell neoplasms

,

transitional cell carcinoma

,

malignant pleural effusion

,

fallopian tube neoplasms

,

small cell carcinoma

,

gastrointestinal neoplasms

,

dna repair-deficiency disorders

,

urinary bladder neoplasms

,

salivary gland neoplasms

,

,

,

radiation injuries

,

radiation effects

,

germ cell and embryonal neoplasms

,

peritoneal neoplasms

,

,

pleural effusion

,

,

residual neoplasm

,

breast neoplasms

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

neoplasm metastasis

,

prostatic neoplasms

,

,

,

small cell lung carcinoma

,

gastroesophageal reflux

,

,

,

,

,

rheumatoid arthritis

,

castration-resistant prostatic neoplasms

,

triple negative breast neoplasms

,

ovarian neoplasms

,

neoplasms by site

,

,

major depressive disorder

,

depressive disorder

,

,

peptic esophagitis

,

,

colorectal neoplasms

,

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

renal cell carcinoma

,

endometrial neoplasms

,

,

,

urologic neoplasms

,

stomach neoplasms

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

kidney diseases

,

,

cardiovascular diseases

,

pancreatic neoplasms

,

ovarian epithelial carcinoma

,

breast diseases

,

sickle cell anemia

,

brain neoplasms

,

,

,

opioid-induced constipation

,

,

hypercholesterolemia

,

biliary tract neoplasms

,

gallbladder neoplasms

,

hereditary breast and ovarian cancer syndrome

,

,

chronic renal insufficiency

,

,

,

glucose metabolism disorders

,

metabolic diseases

,

endocrine system diseases

,

hypersensitivity

,

,

kidney neoplasms

,

,

zollinger-ellison syndrome

,

,

peptic ulcer hemorrhage

,

,

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

,

anxiety disorders

,

,

venous thrombosis

,

pulmonary embolism

,

plexiform neurofibroma

,

neurofibromatosis 1

,

unknown primary neoplasms

,

respiratory insufficiency

,

myocardial infarction

,

coronary artery disease

,

bile duct neoplasms

,

cholangiocarcinoma

,

,

respiratory syncytial virus infections

,

uterine neoplasms

,

non-small-cell lung carcinoma

,

,

respiratory tract diseases

,

respiratory tract neoplasms

,

bronchogenic carcinoma

,

thoracic neoplasms

,

bronchial neoplasms

Globulin, immune

hematologic neoplasms

,

,

neoplasm metastasis

,

b-cell leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

biphenotypic leukemia acute

,

,

,

acquired immunodeficiency syndrome

,

,

immunologic deficiency syndromes

,

,

squamous cell carcinoma

,

malignant fibrous histiocytoma

,

pancreatic neoplasms

,

stomach neoplasms

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

t-cell lymphoma

,

endometrial neoplasms

,

uterine cervical neoplasms

,

myelodysplastic syndromes

,

myelodysplastic-myeloproliferative diseases

,

b-cell lymphoma

,

non-small-cell lung carcinoma

,

,

b-cell lymphoma marginal zone

,

plasma cell neoplasms

,

small cell lung carcinoma

,

squamous cell carcinoma of head and neck

,

mantle-cell lymphoma

,

lymphoproliferative disorders

,

,

burkitt lymphoma

,

,

breast neoplasms

,

triple negative breast neoplasms

,

esophageal neoplasms

,

immunoglobulin light-chain amyloidosis

,

,

reactive arthritis

,

waldenstrom macroglobulinemia

,

residual neoplasm

,

myeloid leukemia

,

myeloproliferative disorders

,

lymphatic diseases

,

intestinal neoplasms

,

colonic neoplasms

,

rectal neoplasms

,

,

hairy cell leukemia

,

smoldering multiple myeloma

,

prostatic neoplasms

,

urinary bladder neoplasms

,

uterine neoplasms

,

,

knee osteoarthritis

,

blastic plasmacytoid dendritic cell neoplasm

,

neoadjuvant therapy

,

female genital neoplasms

,

,

non-hodgkin lymphoma

,

,

large b-cell lymphoma diffuse

,

b-cell chronic lymphocytic leukemia

,

colorectal neoplasms

,

follicular lymphoma

,

fallopian tube neoplasms

,

myeloid leukemia acute

,

ovarian neoplasms

,

multiple myeloma

,

,

musculoskeletal diseases

,

,

peritoneal neoplasms

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

brain neoplasms

,

,

juvenile arthritis

,

,

papulosquamous skin diseases

,

,

macular degeneration

,

lymphoid leukemia

,

ovarian epithelial carcinoma

,

,

,

bronchopulmonary dysplasia

,

respiratory syncytial viruses

,

pyoderma gangrenosum

,

spondylarthropathies

,

spinal diseases

,

,

intermediate uveitis

,

posterior uveitis

,

retinal diseases

,

wet macular degeneration

,

retinal degeneration

,

,

choroidal neovascularization

,

hepatocellular carcinoma

,

liver neoplasms

,

,

rheumatoid arthritis

,

,

,

,

ulcerative colitis

,

psoriatic arthritis

,

ankylosing spondylitis

,

inflammatory bowel diseases

,

,

hidradenitis suppurativa

,

axial spondyloarthritis

,

spondylarthritis

,

cardiovascular diseases

,

connective tissue diseases

,

,

pathologic constriction

,

intestinal diseases

,

,

atopic dermatitis

,

atherosclerosis

,

drug monitoring

hemolytic-uremic syndrome

,

kidney diseases

,

,

,

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