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Trade Name	Drug Name	Approved	Patent Expires	Indication
Benznidazole	Benznidazole	2017-08-29		Chagas disease , Bacterial infections , Protozoan infections
Estradiol	Estradiol	2022-08-10	2024-2037	Prostatic neoplasms , Breast neoplasms , Menorrhagia , Contraception , Primary ovarian insufficiency , Hot flashes , Hypogonadism , Premature menopause , Leiomyoma , Uterine hemorrhage , Amenorrhea , Endometrial hyperplasia , Female infertility , Acne vulgaris , Endometriosis , Delayed puberty , Renal cell carcinoma , Endometrial neoplasms , Hypoventilation , Abdominal pain
Nuvessa	Metronidazole	2014-03-24	2024-2039	Rosacea , Bacterial infections , Giardiasis , Helicobacter infections , Surgical wound infection , Abscess , Bacterial vaginosis , Bacterial endocarditis , Bacterial meningitis , Protozoan infections , Amebiasis , Pseudomembranous enterocolitis , Trichomonas vaginitis , Bacteroides infections , Acne vulgaris , Nausea , Virus diseases , Diarrhea , Gonorrhea , Cholera , Escherichia coli infections , Campylobacter infections , Bacillary dysentery , Chlamydia infections , Bronchitis , Streptococcal infections , Dyspepsia , Bartonella infections , Bacterial eye infections , Syphilis , Staphylococcal infections , Stomach diseases , Borrelia infections , Rickettsia infections , Mycoplasma infections , Chancroid , Granuloma inguinale , Psittacosis

Clinical Trials

Therapeutic Areas:

All

Classification:

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Approval:

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Status:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

pharmacokinetics

,

therapeutic equivalency

,

,

diabetes mellitus

,

drug interactions

,

,

,

,

,

long qt syndrome

,

type 1 diabetes mellitus

,

systemic scleroderma

,

diffuse scleroderma

,

diabetes insipidus

,

duchenne muscular dystrophy

,

muscular dystrophies

,

,

systemic lupus erythematosus

,

,

blood coagulation disorders

,

hemostatic disorders

,

chronic hepatitis c

,

,

electrocardiography

,

pregnancy complications

,

,

antibiotic prophylaxis

,

cerebral arterial diseases

,

renal cell carcinoma

,

hematologic neoplasms

,

human influenza

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

chronic hepatitis b

,

polycythemia vera

,

autoimmune diseases

,

orthostatic hypotension

,

,

interstitial lung diseases

,

biological availability

,

psoriatic arthritis

,

inflammatory bowel diseases

,

muscular atrophy

,

,

adenomatous polyposis coli

,

,

,

respiratory tract infections

,

drug-related side effects and adverse reactions

,

acute coronary syndrome

,

lice infestations

,

restless legs syndrome

,

,

complex partial epilepsy

,

,

falciparum malaria

,

,

phenylketonurias

,

alcoholic fatty liver

,

pharmacological phenomena

,

,

postoperative pain

,

oocyte retrieval

,

,

neurogenic diabetes insipidus

,

,

,

,

cardiac arrhythmias

,

tissue adhesions

,

type 2 diabetes mellitus

,

acquired immunodeficiency syndrome

,

,

male breast neoplasms

,

,

,

gender identity

,

intracranial aneurysm

,

,

,

feeding and eating disorders

,

bulimia nervosa

,

temporomandibular joint disorders

,

myofascial pain syndromes

,

temporomandibular joint dysfunction syndrome

,

,

vulvar vestibulitis

,

metabolic diseases

,

,

behavior and behavior mechanisms

,

orthostatic intolerance

,

,

binge-eating disorder

,

irritable bowel syndrome

,

chronic fatigue syndrome

,

,

tension-type headache

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

carcinoma in situ

,

ductal carcinoma

,

intraductal carcinoma noninfiltrating

,

,

,

,

androgen-insensitivity syndrome

,

central sleep apnea

,

hypoventilation

,

memory disorders

,

habitual abortion

,

,

,

,

male contraceptive devices

,

hidradenitis suppurativa

,

,

prehypertension

,

hereditary breast and ovarian cancer syndrome

,

vascular diseases

,

bipolar disorder

,

cerebral small vessel diseases

,

rotator cuff injuries

,

,

prostatic neoplasms

,

,

,

anorexia nervosa

,

,

pituitary diseases

,

,

,

non-alcoholic fatty liver disease

,

,

intraabdominal infections

,

,

,

metabolic bone diseases

,

cognitive dysfunction

,

,

endometrial neoplasms

,

,

rheumatoid arthritis

,

,

,

,

non-small-cell lung carcinoma

,

,

triple negative breast neoplasms

,

post-traumatic stress disorders

,

intracytoplasmic sperm injections

,

,

congenital abnormalities

,

multiple myeloma

,

plasma cell neoplasms

,

community-acquired pneumonia

,

sleep apnea syndromes

,

oxidative stress

,

,

ovarian pregnancy

,

multiple sclerosis

,

neoplasm metastasis

,

helicobacter infections

,

alzheimer disease

,

,

pelvic infection

,

pelvic inflammatory disease

,

neural tube defects

,

spinal dysraphism

,

myelodysplastic syndromes

,

ovarian neoplasms

,

myeloproliferative disorders

,

myelodysplastic-myeloproliferative diseases

,

,

,

,

,

environmental biomarkers

,

,

,

,

,

,

wound infection

,

,

postoperative complications

,

,

aspiration pneumonia

,

,

,

arnold-chiari malformation

,

cervical ripening

,

,

,

,

,

,

,

germ cell and embryonal neoplasms

,

trophoblastic neoplasms

,

newborn infant diseases

,

hereditary congenital and neonatal diseases and abnormalities

,

nervous system malformations

,

essential hypertension

,

klinefelter syndrome

,

disease susceptibility

,

prosthesis-related infections

,

,

,

healthy volunteers/patients

,

,

,

,

polycystic ovary syndrome

,

breast neoplasms

,

,

female infertility

,

,

,

,

atrophic vaginitis

,

,

,

,

primary ovarian insufficiency

,

,

,

,

communicable diseases

,

embryo transfer

,

,

premature menopause

,

depressive disorder

,

uterine hemorrhage

,

,

,

cardiovascular diseases

,

,

turner syndrome

,

gonadal dysgenesis

,

,

premature birth

,

,

hormone replacement therapy

,

insulin resistance

,

,

gender dysphoria

,

hyperandrogenism

,

premenstrual syndrome

,

,

ovulation inhibition

,

,

migraine disorders

,

,

,

,

,

,

menstruation disturbances

,

,

wounds and injuries

,

,

postpartum depression

,

,

metabolic syndrome

,

,

chronic bronchitis

,

,

,

,

urinary tract infections

,

,

,

ovarian hyperstimulation syndrome

,

,

contraception behavior

,

psychotic disorders

,

cystic fibrosis

,

overactive urinary bladder

,

bacterial infections

,

spontaneous abortion

,

atherosclerosis

,

,

,

,

sleep initiation and maintenance disorders

,

cataract extraction

,

,

ovulation induction

,

estrogen replacement therapy

,

,

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

premenstrual dysphoric disorder

,

suicidal ideation

,

,

pelvic organ prolapse

,

,

hormonal contraception

,

urinary incontinence

,

,

,

,

,

endophthalmitis

,

pelvic floor disorders

,

ovarian reserve

,

male infertility

,

heart disease risk factors

,

embryo implantation

,

endometrial hyperplasia

,

ovarian diseases

,

,

venous thrombosis

,

chronic obstructive pulmonary disease

,

postcoital contraception

,

major depressive disorder

,

interstitial cystitis

,

,

,

,

,

,

postmenopausal osteoporosis

,

bacterial conjunctivitis

,

physiological sexual dysfunction

,

uterine diseases

,

hyperprolactinemia

,

,

bariatric surgery

,

inborn genetic diseases

,

,

,

,

,

bacterial vaginosis

,

psychological stress

,

,

asymptomatic diseases

,

,

lower urinary tract symptoms

,

body weight changes

,

hypersensitivity

,

,

stress urinary incontinence

,

,

vision disorders

,

disease progression

,

,

,

fecal incontinence

,

,

obstructive lung diseases

,

,

pyogenic liver abscess

,

left ventricular dysfunction

,

ventricular dysfunction

,

pregnancy outcome

,

fertilization in vitro

,

abdominal obesity

,

,

blood coagulation

,

,

smoking cessation

,

smoking reduction

,

marijuana abuse

,

,

,

premature aging

,

,

sleep deprivation

,

,

psychological distress

,

,

developmental bone diseases

,

,

cryopreservation

,

psychophysiologic disorders

,

somatoform disorders

,

vaginal diseases

,

,

pharmacogenomic testing

,

,

ataxia telangiectasia

,

,

cerebellar ataxia

,

failure to thrive

,

chronic periodontitis

,

,

intravitreal injections

,

maxillary sinusitis

,

,

microvascular angina

,

arteriosclerosis

,

congenital adrenal hyperplasia

,

adrenogenital syndrome

,

adrenocortical hyperfunction

,

,

mental disorders

,

retinal detachment

,

,

bacterial endocarditis

,

,

cerebrovascular disorders

,

urge urinary incontinence

,

,

female urogenital diseases

,

urogenital diseases

,

musculoskeletal diseases

,

venous thromboembolism

,

thromboembolism

,

endocrine system diseases

,

menstrual cycle

,

cerebrospinal fluid leak

,

uterine cervical neoplasms

,

traumatic brain injuries

,

,

vascular stiffness

,

kidney diseases

,

psychological sexual dysfunctions

,

pathologic dilatation

,

,

appetitive behavior

,

,

,

myocardial infarction

,

,

,

post-acute covid-19 syndrome

,

feeding behavior

,

,

torsades de pointes

,

reproductive behavior

,

kallmann syndrome

,

chemical and drug induced liver injury

,

localized scleroderma

,

in vitro oocyte maturation techniques

,

hematologic diseases

,

hypothalamic diseases

,

disease-free survival

,

,

,

obstructive sleep apnea

,

liver cirrhosis

,

subarachnoid hemorrhage

,

hypopituitarism

,

,

,

,

autonomic nervous system diseases

,

fragile x syndrome

,

beta-thalassemia

,

,

vitamin d deficiency

,

colorectal neoplasms

,

alcohol drinking

,

,

pregnancy-induced hypertension

,

acute kidney injury

,

,

pulmonary arterial hypertension

,

ankylosing spondylitis

,

spondylarthritis

,

,

lipid metabolism disorders

,

,

affective symptoms

,

adolescent development

,

preimplantation diagnosis

,

angelman syndrome

,

,

ectopic pregnancy

,

premature cardiac complexes

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

phobic disorders

,

,

,

peripheral nerve injuries

,

,

seborrheic dermatitis

,

,

premature obstetric labor

,

hyperlipidemias

,

,

neurosurgical procedures

,

executive function

,

respiratory tract diseases

,

respiration disorders

,

,

pulmonary embolism

,

,

intracranial thrombosis

,

intracranial sinus thrombosis

,

,

abdominal abscess

,

bacterial skin diseases

,

bronchial diseases

,

hypercholesterolemia

,

,

ischemic stroke

,

spinal injuries

,

,

perceptual disorders

,

auditory perceptual disorders

,

psychoacoustics

,

,

,

neurologic manifestations

,

,

,

precancerous conditions

,

,

retinal diseases

,

diabetic retinopathy

,

anxiety disorders

,

critical illness

,

recreational drug use

,

meibomian gland dysfunction

,

epidermolysis bullosa simplex

,

epidermolysis bullosa

,

disorders of sex development

,

epidermolysis bullosa dystrophica

,

junctional epidermolysis bullosa

,

observational studies as topic

,

uterine cervical dysplasia

,

periodontal diseases

,

high-risk pregnancy

,

vulvar diseases

,

chronic renal insufficiency

,

,

lobular carcinoma

,

lymphadenopathy

,

cesarean section

,

,

emotional regulation

,

stress fractures

,

relative energy deficiency in sport

,

delayed puberty

,

,

cardiorespiratory fitness

,

aplastic anemia

,

uterine neoplasms

Estradiol benzoate

hematologic neoplasms

,

,

,

uterine hemorrhage

,

,

,

,

,

healthy volunteers/patients

,

,

trypanosomiasis

,

,

,

Estradiol valerate

hematologic neoplasms

,

,

,

uterine hemorrhage

,

,

,

,

,

Antithrombin iii

healthy volunteers/patients

,

,

non-alcoholic fatty liver disease

,

,

,

hepatic insufficiency

,

chronic renal insufficiency

,

chronic kidney failure

,

cardiovascular diseases

,

alzheimer disease

,

coronary disease

,

acute coronary syndrome

,

cardiac catheterization

,

heart valve prosthesis

,

venous thrombosis

,

,

,

,

non-small-cell lung carcinoma

,

replacement arthroplasty knee

,

,

secondary prevention

,

neoplasm metastasis

,

,

,

ischemic stroke

,

squamous cell carcinoma

,

,

percutaneous coronary intervention

,

replacement arthroplasty hip

,

intracranial sinus thrombosis

,

type 2 diabetes mellitus

,

,

squamous cell carcinoma of head and neck

,

,

,

atrial fibrillation

,

thromboembolism

,

venous thromboembolism

,

renal insufficiency

,

,

myocardial infarction

,

,

cognitive dysfunction

,

replacement arthroplasty

,

heart valve diseases

,

,

,

,

,

cerebral infarction

,

,

cognition disorders

,

coronary artery disease

,

myocardial ischemia

,

transient ischemic attack

,

,

small cell lung carcinoma

Sodium chloride

bacterial infections

,

gram-negative bacterial infections

,

hypertriglyceridemia

,

allergic rhinitis

,

,

,

migraine disorders

,

systemic lupus erythematosus

,

cutaneous lupus erythematosus

,

staphylococcal infections

,

,

,

respiratory syncytial viruses

,

sickle cell anemia

,

type 2 diabetes mellitus

,

diabetes mellitus

,

streptococcal infections

,

alzheimer disease

,

respiratory tract infections

,

borrelia infections

,

,

meningococcal infections

,

cerebral amyloid angiopathy

,

,

familial cerebral amyloid angiopathy

,

,

pulmonary sarcoidosis

,

serogroup b neisseria meningitidis

,

esophageal neoplasms

,

ventilator-associated pneumonia

,

,

,

healthy volunteers/patients

,

,

pneumococcal infections

,

,

clostridium infections

,

,

clostridioides difficile

,

meningococcal meningitis

,

human influenza

,

essential hypertension

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

community-acquired infections

,

bacterial pneumonia

,

,

headache disorders

,

,

renal cell carcinoma

,

,

gastrointestinal stromal tumors

,

,

alopecia areata

,

,

,

,

postoperative pain

,

,

pneumococcal pneumonia

,

streptococcus pneumoniae

,

,

hyperlipidemias

,

,

cardiovascular diseases

,

health risk behaviors

,

vascular stiffness

hepatic insufficiency

,

renal insufficiency

,

castration-resistant prostatic neoplasms

,

,

,

,

,

unknown primary neoplasms

,

immunomodulation

,

gram-positive bacterial infections

,

t-cell lymphoma peripheral

,

,

merkel cell carcinoma

,

mycosis fungoides

,

clear cell sarcoma

,

myelodysplastic syndromes

,

,

,

pulmonary sarcoidosis

,

lyme neuroborreliosis

,

hypertriglyceridemia

,

,

granuloma annulare

,

mycobacterium avium complex

,

thoracic neoplasms

,

pelvic neoplasms

,

,

,

brain neoplasms

,

stomach neoplasms

,

,

triple negative breast neoplasms

,

multiple myeloma

,

head and neck neoplasms

,

urinary bladder neoplasms

,

ovarian neoplasms

,

thyroid neoplasms

,

plasma cell neoplasms

,

,

small cell lung carcinoma

,

ovarian epithelial carcinoma

,

esophageal neoplasms

,

borrelia infections

,

endometrial neoplasms

,

thyroid diseases

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

uveal neoplasms

,

respiratory syncytial viruses

,

,

,

transitional cell carcinoma

,

kidney diseases

,

small cell carcinoma

,

adenocarcinoma of lung

,

large-cell lymphoma anaplastic

,

,

,

pheochromocytoma

,

,

healthcare-associated pneumonia

,

systemic lupus erythematosus

,

alopecia areata

,

,

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

oligodendroglioma

,

,

hemangioblastoma

,

urogenital neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

germ cell and embryonal neoplasms

,

carcinoid tumor

,

urethral neoplasms

,

ureteral neoplasms

,

alveolar soft part sarcoma

,

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

cholangiocarcinoma

,

gene rearrangement

,

lobular carcinoma

,

plasma cell leukemia

,

medulloblastoma

,

,

rhabdomyosarcoma

,

diffuse intrinsic pontine glioma

,

intraductal carcinoma noninfiltrating

,

b-cell lymphoma

,

cutaneous lupus erythematosus

,

keratoconjunctivitis

,

,

respiratory tract infections

,

,

,

,

hidradenitis suppurativa

,

,

meningococcal infections

,

neoadjuvant therapy

,

diabetes mellitus

,

type 1 diabetes mellitus

,

,

multidrug-resistant tuberculosis

,

von hippel-lindau disease

,

,

,

neurodermatitis

,

,

urologic neoplasms

,

urologic diseases

,

neoplasms by site

,

glandular and epithelial neoplasms

,

,

,

benign fibrous histiocytoma

,

,

malignant fibrous histiocytoma

,

myeloid leukemia accelerated phase

,

,

malignant mesothelioma

,

,

urinary bladder diseases

,

adrenal cortex neoplasms

,

adrenocortical carcinoma

,

second primary neoplasms

,

pulmonary tuberculosis

,

hematologic neoplasms

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

mouth neoplasms

,

,

penile neoplasms

,

plexiform neurofibroma

,

,

testicular neoplasms

,

solitary fibrous tumors

,

,

hemangiopericytoma

,

male urogenital diseases

,

urogenital diseases

,

,

adenoid cystic carcinoma

,

,

hemangiosarcoma

,

systemic scleroderma

,

diffuse scleroderma

,

,

,

post-acute covid-19 syndrome

,

,

colorectal neoplasms

,

atopic dermatitis

,

,

,

,

,

kidney neoplasms

,

prostatic neoplasms

,

squamous cell carcinoma

,

hepatocellular carcinoma

,

liver neoplasms

,

pancreatic neoplasms

,

neoplasm metastasis

,

,

psoriatic arthritis

,

squamous cell neoplasms

,

squamous cell carcinoma of head and neck

,

,

male breast neoplasms

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

myeloid leukemia chronic-phase

,

juvenile arthritis

,

,

,

bacterial pneumonia

,

,

mycobacterium avium-intracellulare infection

,

immune system diseases

,

inborn genetic diseases

,

genetic skin diseases

,

eczematous skin diseases

,

hypersensitivity

,

immediate hypersensitivity

,

islet cell carcinoma

,

ankylosing spondylitis

,

bacterial infections

,

pancreatic ductal carcinoma

,

,

,

febrile neutropenia

,

,

mycobacterium infections

,

adenosquamous carcinoma

,

large cell carcinoma

,

nervous system diseases

,

optic nerve diseases

,

disease progression

,

cardiovascular diseases

,

immunologic deficiency syndromes

,

breast neoplasms

,

healthy volunteers/patients

,

,

renal cell carcinoma

,

non-small-cell lung carcinoma

,

,

,

rheumatoid arthritis

,

,

,

,

,

acquired immunodeficiency syndrome

,

communicable diseases

,

bcr-abl positive chronic myelogenous leukemia

,

,

myeloid leukemia

,

neuroendocrine tumors

,

gastrointestinal stromal tumors

,

ulcerative colitis

,

,

,

non-hodgkin lymphoma

,

kidney transplantation

,

philadelphia chromosome

,

islet cell adenoma

,

intraabdominal infections

,

mantle-cell lymphoma

,

,

spondylarthritis

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

,

,

,

,

,

ventilator-associated pneumonia

,

chronic hepatitis c

,

,

axial spondyloarthritis

,

,

premature birth

,

bacterial vaginosis

,

vaginal diseases

,

,

infectious skin diseases

,

soft tissue infections

,

,

,

community-acquired infections

,

staphylococcal infections

,

,

hypercholesterolemia

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

bacterial skin diseases

,

,

asymptomatic infections

,

,

,

respiratory tract diseases

hemolytic-uremic syndrome

,

,

,

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