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Alexion Pharmaceuticals
Alexion Pharmaceuticals
(ALXN)
Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.
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Clinical Trials
Financial
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Company Revenue
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Revenue by Drug
Marketed Drugs
Therapeutic Areas:
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Classification:
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Include Generics:
Trade Name
Drug Name
Approved
Patent Expires
Indication
Kanuma
Sebelipase alfa
2015-12-08
Inborn errors lipid metabolism
Soliris
Eculizumab
2007-03-16
Paroxysmal hemoglobinuria
,
Myasthenia gravis
,
Atypical hemolytic uremic syndrome
Strensiq
Asfotase alfa
2015-10-23
Hypophosphatasia
Ultomiris
Ravulizumab
2018-12-21
Paroxysmal hemoglobinuria
,
Atypical hemolytic uremic syndrome
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Ravulizumab
healthy volunteers/patients
,
lupus nephritis
,
hemolysis
,
myasthenia gravis
,
kidney diseases
,
neuromyelitis optica
,
muscle weakness
,
vascular diseases
,
thrombotic microangiopathies
,
iga glomerulonephritis
,
syndrome
,
hemolytic-uremic syndrome
,
atypical hemolytic uremic syndrome
,
nephritis
,
azotemia
,
covid-19
,
respiratory distress syndrome
,
pneumonia
,
acute lung injury
,
viral pneumonia
,
lung injury
,
newborn respiratory distress syndrome
,
amyotrophic lateral sclerosis
,
motor neuron disease
,
sclerosis
,
dermatomyositis
,
chronic renal insufficiency
,
cardiopulmonary bypass
,
heart diseases
,
kidney transplantation
,
delayed graft function
,
iga vasculitis
,
vasculitis
,
purpura
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
pregnancy
Asfotase alfa
hypophosphatasia
Sebelipase alfa
fabry disease
,
cholesterol ester storage disease
,
wolman disease
,
failure to thrive
Eculizumab
glomerulonephritis
,
membranoproliferative glomerulonephritis
,
liver diseases
,
end stage liver disease
,
azotemia
,
kidney transplantation
,
kidney diseases
,
vasculitis
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
pre-eclampsia
,
pregnancy rate
,
hellp syndrome
,
complement activation
,
chronic renal insufficiency
,
hemolytic anemia autoimmune
,
death
,
macular degeneration
,
geographic atrophy
,
asthma
,
hemolysis
,
syndrome
,
hemolytic-uremic syndrome
,
atypical hemolytic uremic syndrome
,
myasthenia gravis
,
neuromyelitis optica
,
muscle weakness
,
delayed graft function
,
guillain-barre syndrome
,
left ventricular dysfunction
,
ventricular dysfunction
,
escherichia coli infections
,
shiga-toxigenic escherichia coli
,
phenylketonurias
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
covid-19
,
hypophosphatasia
,
respiratory distress syndrome
,
pneumonia
,
acute lung injury
,
viral pneumonia
,
lung injury
,
newborn respiratory distress syndrome
,
pregnancy
,
disease progression
Danicopan
healthy volunteers/patients
,
liver diseases
,
hepatic insufficiency
,
renal insufficiency
,
glomerulonephritis
,
membranoproliferative glomerulonephritis
,
macular degeneration
,
geographic atrophy
,
atrophy
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
hemolysis
Mycophenolate sodium
kidney transplantation
,
delayed graft function
,
diffuse scleroderma
,
sclerosis
,
lupus nephritis
,
nephritis
,
systemic lupus erythematosus
,
systemic scleroderma
,
myositis
,
juvenile arthritis
,
behcet syndrome
,
dermatomyositis
,
ankylosing spondylitis
,
rheumatoid arthritis
,
arthritis
,
vasculitis
,
sjogren's syndrome
,
rheumatic diseases
,
herpes zoster
,
spondylarthritis
,
spondylitis
,
systemic vasculitis
,
collagen diseases
Mycophenolic acid
kidney transplantation
,
delayed graft function
,
diffuse scleroderma
,
sclerosis
,
lupus nephritis
,
nephritis
,
systemic lupus erythematosus
,
systemic scleroderma
,
myositis
,
juvenile arthritis
,
behcet syndrome
,
dermatomyositis
,
ankylosing spondylitis
,
rheumatoid arthritis
,
arthritis
,
vasculitis
,
sjogren's syndrome
,
rheumatic diseases
,
herpes zoster
,
spondylarthritis
,
spondylitis
,
systemic vasculitis
,
collagen diseases
Iron dextran
fatigue
,
cognition
,
energy metabolism
,
cerebrovascular circulation
,
iron deficiencies
,
iron-deficiency anemia
,
liver diseases
,
carcinoma
,
hepatocellular carcinoma
,
liver neoplasms
Cerdulatinib
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
leukemia
,
lymphoma
,
t-cell lymphoma
,
hodgkin disease
,
follicular lymphoma
,
b-cell lymphoma
,
lymphoid leukemia
Lampalizumab
juvenile arthritis
,
arthritis
Pexelizumab
myocardial infarction
,
infarction
,
inferior wall myocardial infarction
,
coronary artery disease
,
cardiopulmonary bypass
,
coronary artery bypass
Tenofovir
hepatitis c
,
virus diseases
,
breast feeding
,
pregnancy
,
hiv infections
,
acquired immunodeficiency syndrome
,
infections
,
communicable diseases
,
immunologic deficiency syndromes
,
hiv
,
sarcoma
,
kaposi sarcoma
,
hepatitis b
,
hepatitis
,
hepatitis a
,
liver cirrhosis
,
fibrosis
,
biliary liver cirrhosis
,
lipodystrophy
Doconexent
ovarian neoplasms
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
recurrence
,
b-cell lymphoma marginal zone
,
lymphoma
,
lung neoplasms
,
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
non-small-cell lung carcinoma
,
follicular lymphoma
,
leukemia
,
esophageal neoplasms
,
b-cell lymphoma
,
respiratory distress syndrome
,
acute lung injury
,
newborn respiratory distress syndrome
,
syndrome
,
urologic neoplasms
,
transitional cell carcinoma
,
neoplasms
,
multiple myeloma
,
breast neoplasms
,
adenocarcinoma
,
biliary tract neoplasms
,
gallbladder neoplasms
,
precancerous conditions
,
peripheral nervous system diseases
,
paraproteinemias
,
monoclonal gammopathy of undetermined significance
,
pancreatic neoplasms
,
head and neck neoplasms
,
mantle-cell lymphoma
,
kidney diseases
,
iga glomerulonephritis
Alfacalcidol
ulcerative colitis
,
colitis
,
ulcer
Terfenadine
leukemia
,
healthy volunteers/patients
,
myeloid leukemia acute
,
myeloid leukemia
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
lymphoma
,
non-hodgkin lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
lupus nephritis
,
nephritis
,
multiple sclerosis
,
sclerosis
,
systemic lupus erythematosus
,
chronic progressive multiple sclerosis
,
kidney diseases
,
membranous glomerulonephritis
,
relapsing-remitting multiple sclerosis
,
nephrotic syndrome
,
syndrome
,
nephrosis
,
lipoid nephrosis
,
rheumatoid arthritis
,
arthritis
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