Alexion Pharmaceuticals - PharmaKB

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Company ReportsAlexion Pharmaceuticals

Alexion Pharmaceuticals(ALXN)

Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.

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Financial

Marketed Drugs

Clinical Trials

Financial

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*Currency in USD

Company Revenue

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Annual

Annual

Projections

*Quarterly sales USD (in millions)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Kanuma	Sebelipase alfa	2015-12-08		Inborn errors lipid metabolism
Soliris	Eculizumab	2007-03-16		Paroxysmal hemoglobinuria , Myasthenia gravis , Atypical hemolytic uremic syndrome
Strensiq	Asfotase alfa	2015-10-23		Hypophosphatasia
Ultomiris	Ravulizumab	2018-12-21		Paroxysmal hemoglobinuria, Atypical hemolytic uremic syndrome

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hypophosphatasia

Sebelipase alfa

mucopolysaccharidosis iv

,

glycogen storage disease type ii

,

lysosomal storage diseases

,

gaucher disease

,

,

cholesterol ester storage disease

,

,

failure to thrive

healthy volunteers/patients

,

,

end stage liver disease

,

kidney diseases

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

,

chronic kidney failure

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

,

multiple organ failure

,

diabetes mellitus

,

thrombocytopenia

,

complement activation

,

psychology rejection

,

renal insufficiency

,

wounds and injuries

,

reperfusion injury

,

chronic renal insufficiency

,

hemolytic anemia autoimmune

,

,

antiphospholipid syndrome

,

macular degeneration

,

geographic atrophy

,

,

dermatomyositis

,

autoimmune diseases

,

neuromyelitis optica

,

myasthenia gravis

,

kidney transplantation

,

muscle weakness

,

vascular diseases

,

thrombotic microangiopathies

,

guillain-barre syndrome

,

delayed graft function

,

escherichia coli infections

,

,

left ventricular dysfunction

,

ventricular dysfunction

,

shiga-toxigenic escherichia coli

,

,

,

malignant hypertension

,

hypertensive crisis

,

phenylketonurias

,

paroxysmal hemoglobinuria

,

,

,

,

hemolytic-uremic syndrome

,

atypical hemolytic uremic syndrome

,

,

,

coronavirus infections

,

respiratory distress syndrome

,

,

acute lung injury

,

hypophosphatasia

,

severe acute respiratory syndrome

,

viral pneumonia

,

,

newborn respiratory distress syndrome

,

,

protein-losing enteropathies

,

intestinal diseases

,

,

lymphangiectasis

,

intestinal lymphangiectasis

,

,

disease progression

,

intestinal obstruction

,

,

allergic fungal sinusitis

,

,

healthy volunteers/patients

,

hepatic insufficiency

,

renal insufficiency

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

geographic atrophy

,

paroxysmal hemoglobinuria

,

,

healthy volunteers/patients

,

type 2 diabetes mellitus

,

,

,

,

,

respiratory syncytial virus infections

,

brain neoplasms

,

non-small-cell lung carcinoma

,

central nervous system neoplasms

,

,

glucose metabolism disorders

,

metabolic diseases

,

alzheimer disease

,

huntington disease

,

sickle cell anemia

,

atopic dermatitis

,

anxiety disorders

,

prostatic neoplasms

,

colorectal neoplasms

,

breast neoplasms

,

,

adenocarcinoma of lung

,

generalized anxiety disorder

,

reflex epilepsy

,

bipolar disorder

,

diabetes mellitus

,

,

status epilepticus

,

critical illness

,

,

psychomotor agitation

,

post-traumatic stress disorders

,

executive function

,

,

partial epilepsies

,

generalized epilepsy

,

complex partial epilepsy

,

,

insulin resistance

,

metabolic syndrome

,

,

major depressive disorder

,

depressive disorder

,

psychotic disorders

,

gastrointestinal endoscopy

,

hyperlipidemias

,

b-cell chronic lymphocytic leukemia

,

,

hodgkin disease

,

b-cell lymphoma

,

t-cell lymphoma cutaneous

,

bronchiolitis obliterans syndrome

,

,

t-cell lymphoma

,

follicular lymphoma

,

,

large-cell lymphoma anaplastic

,

t-cell lymphoma peripheral

,

non-hodgkin lymphoma

coronary artery disease

,

cardiopulmonary bypass

,

coronary artery bypass

,

,

,

chronic hepatitis b

,

,

chronic hepatitis

,

Choline alfoscerate

general anesthesia

,

neuromuscular blockade

type 2 diabetes mellitus

,

glucose metabolism disorders

,

metabolic diseases

,

diabetes mellitus

,

endocrine system diseases

,

,

neuroendocrine tumors

b-cell lymphoma

,

inflammatory breast neoplasms

,

immunoglobulin light-chain amyloidosis

,

,

myeloproliferative disorders

,

primary myelofibrosis

,

promyelocytic leukemia acute

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia acute

,

myelomonocytic leukemia juvenile

,

,

systemic scleroderma

,

diffuse scleroderma

,

,

large b-cell lymphoma diffuse

,

,

myeloid leukemia acute

,

precursor cell lymphoblastic leukemia-lymphoma

,

non-hodgkin lymphoma

,

lymphoid leukemia

,

,

myeloid leukemia

,

myelodysplastic syndromes

,

multiple myeloma

,

plasma cell neoplasms

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

b-cell chronic lymphocytic leukemia

,

triple negative breast neoplasms

,

refractory anemia with excess of blasts

,

renal insufficiency

,

hematologic diseases

,

blood protein disorders

,

neoplasms by histologic type

,

paraproteinemias

,

hodgkin disease

,

diabetes mellitus

,

type 1 diabetes mellitus

,

prolymphocytic leukemia t-cell

,

prolymphocytic leukemia

,

,

burkitt lymphoma

,

graft vs host disease

,

bronchiolitis obliterans syndrome

,

aplastic anemia

,

breast neoplasms

,

brain stem neoplasms

,

glycogen storage disease type ii

,

glycogen storage disease type iii

,

ovarian neoplasms

,

hematologic neoplasms

1

2

3

4

5

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