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Company ReportsAlexion Pharmaceuticals

Alexion Pharmaceuticals(ALXN)

Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.

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Clinical Trials

Financial

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Company Revenue

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Kanuma	Sebelipase alfa	2015-12-08		Inborn errors lipid metabolism
Soliris	Eculizumab	2007-03-16		Paroxysmal hemoglobinuria , Atypical hemolytic uremic syndrome
Strensiq	Asfotase alfa	2015-10-23		Hypophosphatasia
Ultomiris	Ravulizumab	2018-12-21		Paroxysmal hemoglobinuria, Atypical hemolytic uremic syndrome

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hypophosphatasia

Sebelipase alfa

mucopolysaccharidosis iv

,

glycogen storage disease type ii

,

lysosomal storage diseases

,

gaucher disease

,

,

cholesterol ester storage disease

,

,

failure to thrive

healthy volunteers/patients

,

,

end stage liver disease

,

kidney diseases

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

,

chronic kidney failure

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

,

multiple organ failure

,

diabetes mellitus

,

thrombocytopenia

,

complement activation

,

renal insufficiency

,

wounds and injuries

,

reperfusion injury

,

chronic renal insufficiency

,

hemolytic anemia autoimmune

,

,

antiphospholipid syndrome

,

macular degeneration

,

geographic atrophy

,

,

dermatomyositis

,

autoimmune diseases

,

neuromyelitis optica

,

myasthenia gravis

,

kidney transplantation

,

muscle weakness

,

vascular diseases

,

thrombotic microangiopathies

,

guillain-barre syndrome

,

delayed graft function

,

escherichia coli infections

,

,

left ventricular dysfunction

,

ventricular dysfunction

,

shiga-toxigenic escherichia coli

,

,

,

malignant hypertension

,

hypertensive crisis

,

phenylketonurias

,

paroxysmal hemoglobinuria

,

,

,

,

hemolytic-uremic syndrome

,

atypical hemolytic uremic syndrome

,

,

,

coronavirus infections

,

hypophosphatasia

,

respiratory distress syndrome

,

,

acute lung injury

,

viral pneumonia

,

,

newborn respiratory distress syndrome

,

,

protein-losing enteropathies

,

intestinal diseases

,

,

lymphangiectasis

,

intestinal lymphangiectasis

,

,

disease progression

,

intestinal obstruction

,

,

allergic fungal sinusitis

,

,

healthy volunteers/patients

,

,

hepatic insufficiency

,

renal insufficiency

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

macular degeneration

,

geographic atrophy

,

,

paroxysmal hemoglobinuria

,

,

Mycophenolate sodium

autoimmune diseases

Calcium carbonate

metabolic bone diseases

,

overactive urinary bladder

,

urinary incontinence

,

urinary bladder diseases

,

,

,

,

b-cell chronic lymphocytic leukemia

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mantle-cell lymphoma

,

large b-cell lymphoma diffuse

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

,

hodgkin disease

,

b-cell lymphoma

,

lymphoid leukemia

,

,

,

t-cell lymphoma

,

follicular lymphoma

,

large-cell lymphoma anaplastic

,

t-cell lymphoma peripheral

healthy volunteers/patients

,

pancreatic neoplasms

,

myelodysplastic-myeloproliferative diseases

,

leukemia myeloid chronic atypical bcr-abl negative

,

,

,

cutaneous malignant melanoma

,

myeloid sarcoma

,

,

medication adherence

,

second primary neoplasms

,

ovarian epithelial carcinoma

,

,

,

multiple myeloma

,

hematologic neoplasms

,

follicular lymphoma

,

mantle-cell lymphoma

,

biphenotypic leukemia acute

,

t-cell lymphoma

,

neoplasm metastasis

,

ovarian neoplasms

,

large b-cell lymphoma diffuse

,

eyelid neoplasms

,

t-cell lymphoma peripheral

,

myeloid leukemia chronic-phase

,

,

myelomonocytic leukemia acute

,

fallopian tube neoplasms

,

medulloblastoma

,

triple negative breast neoplasms

,

,

b-cell lymphoma marginal zone

,

burkitt lymphoma

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

castration-resistant prostatic neoplasms

,

myeloid leukemia accelerated phase

,

refractory anemia with excess of blasts

,

,

primitive neuroectodermal tumors

,

neuroectodermal tumors

,

renal cell carcinoma

,

,

brain neoplasms

,

extranodal nk-t-cell lymphoma

,

waldenstrom macroglobulinemia

,

large-cell lymphoma anaplastic

,

large-cell lymphoma immunoblastic

,

,

diabetes mellitus

,

,

hepatocellular carcinoma

,

liver neoplasms

,

residual neoplasm

,

,

islet cell adenoma

,

,

nervous system neoplasms

,

primitive neuroectodermal tumors peripheral

,

,

,

oligodendroglioma

,

,

ganglioneuroblastoma

,

ovarian hyperstimulation syndrome

,

,

sezary syndrome

,

immunoblastic lymphadenopathy

,

mycosis fungoides

,

adult t-cell leukemia-lymphoma

,

intraocular lymphoma

,

t-cell lymphoma cutaneous

,

plasmablastic lymphoma

,

t-cell leukemia

,

lymphomatoid granulomatosis

,

sickle cell anemia

,

,

systemic lupus erythematosus

,

biliary tract neoplasms

,

immunologic deficiency syndromes

,

hematopoietic stem cell transplantation

,

erythroblastic leukemia acute

,

pathologic complete response

,

head and neck neoplasms

,

wounds and injuries

,

,

,

thyroid neoplasms

,

papillary thyroid cancer

,

thyroid diseases

,

follicular adenocarcinoma

,

papillary carcinoma

,

type 1 diabetes mellitus

,

urinary retention

,

,

urinary tract infections

,

pelvic organ prolapse

,

,

male breast neoplasms

,

pulmonary alveolar proteinosis

,

hematologic diseases

,

clostridium infections

,

bone marrow transplantation

,

,

basal cell carcinoma

,

merkel cell carcinoma

,

basal cell neoplasms

,

hypersensitivity

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

,

,

non-hodgkin lymphoma

,

myeloproliferative disorders

,

philadelphia chromosome

,

hodgkin disease

,

non-small-cell lung carcinoma

,

geographic atrophy

,

,

breast neoplasms

,

bcr-abl positive chronic myelogenous leukemia

,

plasma cell neoplasms

,

b-cell lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

rhabdomyosarcoma

,

prostatic neoplasms

,

b-cell chronic lymphocytic leukemia

,

central nervous system neoplasms

,

,

,

primary myelofibrosis

,

mucocutaneous lymph node syndrome

,

,

,

,

,

macular degeneration

,

,

,

spinal cord neoplasms

,

,

neuroendocrine tumors

,

colorectal neoplasms

,

induction chemotherapy

,

venous thromboembolism

,

thromboembolism

,

,

,

,

ischemic stroke

,

,

,

brain stem neoplasms

,

muscle spasticity

,

,

invasive hydatidiform mole

,

,

nephrotic syndrome

,

,

pulmonary embolism

,

,

autonomic nervous system diseases

,

,

primary dysautonomias

,

familial dysautonomia

,

hydatidiform mole

,

gestational trophoblastic disease

,

choriocarcinoma

,

trophoblastic neoplasms

,

juvenile arthritis

,

kidney neoplasms

,

,

,

myeloid leukemia acute

,

myeloid leukemia

,

myelodysplastic syndromes

,

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

,

,

rheumatoid arthritis

,

,

,

aplastic anemia

,

,

inflammatory bowel diseases

,

ulcerative colitis

,

,

,

kidney diseases

,

,

iga glomerulonephritis

,

child mortality

,

growth and development

,

critical illness

,

premature birth

,

intestinal diseases

,

lupus nephritis

,

,

kidney transplantation

,

,

,

,

,

acute coronary syndrome

,

coronary artery disease

,

percutaneous coronary intervention

,

gastrointestinal diseases

,

cardiovascular diseases

,

gastrointestinal stromal tumors

,

,

esophageal neoplasms

,

,

chronic hepatitis b

,

,

chronic hepatitis

,

,

thrombocytopenia

,

germ cell and embryonal neoplasms

,

,

retinal neoplasms

,

phenylketonurias

,

heart disease risk factors

,

stomatognathic diseases

,

endocrine system diseases

,

autoimmune diseases

,

cognitive dysfunction

,

neurocognitive disorders

,

major depressive disorder

,

depressive disorder

,

,

type 2 diabetes mellitus

,

chronic periodontitis

,

,

,

drug-related side effects and adverse reactions

,

digestive system diseases

myocardial infarction

,

,

inferior wall myocardial infarction

,

coronary artery disease

,

cardiopulmonary bypass

,

coronary artery bypass

healthy volunteers/patients

Choline alfoscerate

healthy volunteers/patients

,

hepatolenticular degeneration

,

gastrointestinal stromal tumors

,

systemic mastocytosis

,

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2

3

4

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