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Company ReportsAlexion Pharmaceuticals

Alexion Pharmaceuticals(ALXN)

Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.

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Financial

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Kanuma	Sebelipase alfa	2015-12-08		Inborn errors lipid metabolism
Soliris	Eculizumab	2007-03-16		Paroxysmal hemoglobinuria , Myasthenia gravis , Atypical hemolytic uremic syndrome
Strensiq	Asfotase alfa	2015-10-23		Hypophosphatasia
Ultomiris	Ravulizumab	2018-12-21		Paroxysmal hemoglobinuria, Atypical hemolytic uremic syndrome

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hypophosphatasia

Sebelipase alfa

mucopolysaccharidosis iv

,

glycogen storage disease type ii

,

lysosomal storage diseases

,

gaucher disease

,

,

cholesterol ester storage disease

,

,

failure to thrive

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

end stage liver disease

,

,

,

kidney transplantation

,

kidney diseases

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

,

,

complement activation

,

psychology rejection

,

chronic renal insufficiency

,

hemolytic anemia autoimmune

,

,

macular degeneration

,

geographic atrophy

,

,

,

hemolytic-uremic syndrome

,

atypical hemolytic uremic syndrome

,

myasthenia gravis

,

neuromyelitis optica

,

muscle weakness

,

delayed graft function

,

guillain-barre syndrome

,

left ventricular dysfunction

,

ventricular dysfunction

,

escherichia coli infections

,

shiga-toxigenic escherichia coli

,

phenylketonurias

,

paroxysmal hemoglobinuria

,

,

,

respiratory distress syndrome

,

,

acute lung injury

,

hypophosphatasia

,

severe acute respiratory syndrome

,

viral pneumonia

,

,

newborn respiratory distress syndrome

,

,

disease progression

healthy volunteers/patients

,

hepatic insufficiency

,

renal insufficiency

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

geographic atrophy

,

paroxysmal hemoglobinuria

,

,

Mycophenolate sodium

autoimmune diseases

parkinson disease

non-hodgkin lymphoma

,

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

postoperative nausea and vomiting

,

,

b-cell chronic lymphocytic leukemia

,

,

hodgkin disease

,

b-cell lymphoma

,

t-cell lymphoma cutaneous

,

bronchiolitis obliterans syndrome

,

,

t-cell lymphoma

,

follicular lymphoma

,

,

large-cell lymphoma anaplastic

,

t-cell lymphoma peripheral

,

non-hodgkin lymphoma

myocardial infarction

,

,

inferior wall myocardial infarction

,

coronary artery disease

,

cardiopulmonary bypass

,

coronary artery bypass

,

,

,

,

acquired immunodeficiency syndrome

,

,

,

,

,

communicable diseases

,

,

,

biliary liver cirrhosis

,

Choline alfoscerate

healthy volunteers/patients

,

hepatolenticular degeneration

,

insulin resistance

,

,

metabolic diseases

,

,

,

paraneoplastic syndromes

,

glucose metabolism disorders

,

,

,

pulmonary tuberculosis

,

head and neck neoplasms

,

kidney neoplasms

,

colorectal neoplasms

,

colonic neoplasms

,

,

,

,

connective tissue neoplasms

,

,

,

langerhans-cell histiocytosis

,

uveal neoplasms

,

,

,

gastrointestinal stromal tumors

,

rhabdomyosarcoma

,

primitive neuroectodermal tumors peripheral

,

neuroendocrine carcinoma

,

,

pheochromocytoma

,

diabetes mellitus

,

gastrointestinal neoplasms

,

type 1 diabetes mellitus

,

,

prostatic neoplasms

,

small cell lung carcinoma

,

merkel cell carcinoma

,

nervous system neoplasms

,

type 2 diabetes mellitus

,

endocrine system diseases

,

dumping syndrome

,

digestive system neoplasms

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

thyroid neoplasms

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

hereditary hemorrhagic telangiectasia

,

endocrine gland neoplasms

,

germ cell and embryonal neoplasms

,

ovarian neoplasms

,

unknown primary neoplasms

,

somatostatinoma

,

von hippel-lindau disease

,

pituitary acth hypersecretion

,

cushing syndrome

,

premature cardiac complexes

,

carcinoma in situ

,

ductal carcinoma

,

intraductal carcinoma noninfiltrating

,

,

respiratory tract neoplasms

,

multiple endocrine neoplasia

,

islet cell carcinoma

,

acth-secreting pituitary adenoma

,

,

,

,

pleural effusion

,

lymphangioleiomyomatosis

,

lymphangiomyoma

,

,

chylous ascites

,

hematologic diseases

,

inborn genetic diseases

,

pathologic dilatation

,

,

small cell carcinoma

,

attention deficit disorder with hyperactivity

,

,

,

,

,

,

,

bacterial endocarditis

,

,

,

diffuse intrinsic pontine glioma

,

synovial sarcoma

,

desmoplastic small round cell tumor

,

triple negative breast neoplasms

,

carcinoid tumor

,

pancreatic neoplasms

,

,

malignant carcinoid syndrome

,

breast neoplasms

,

islet cell adenoma

,

,

neoplasm metastasis

,

liver neoplasms

,

serotonin syndrome

,

autosomal dominant polycystic kidney

,

hepatocellular carcinoma

,

intestinal neoplasms

,

,

,

polycystic kidney diseases

,

pituitary diseases

,

kidney diseases

,

,

glomerular filtration rate

,

,

carcinoid heart disease

,

,

,

thymus neoplasms

,

,

pancreatic diseases

,

,

retinal diseases

,

diabetic retinopathy

,

,

gallbladder neoplasms

,

pancreaticoduodenectomy

,

,

vascular malformations

,

renal insufficiency

,

,

prader-willi syndrome

,

,

,

neuroendocrine tumors

,

,

,

,

,

,

portal hypertension

,

esophageal and gastric varices

,

liver cirrhosis

,

medulloblastoma

,

stomach neoplasms

,

,

pituitary neoplasms

,

,

central nervous system neoplasms

,

healthy volunteers/patients

,

,

gastrointestinal hemorrhage

,

pancreatic fistula

,

congenital hyperinsulinism

,

nesidioblastosis

,

hyperinsulinism

,

brain neoplasms

,

acute kidney injury

,

hemangioblastoma

,

olfactory esthesioneuroblastoma

,

intestinal obstruction

,

end stage liver disease

,

acute necrotizing pancreatitis

,

,

non-alcoholic fatty liver disease

,

esophageal neoplasms

,

,

,

,

,

duodenal neoplasms

,

,

glucose intolerance

,

papillary thyroid cancer

,

,

venous thrombosis

,

surgical portasystemic shunt

,

postoperative pain

,

,

circulating neoplastic cells

,

alcoholic fatty liver

,

renal circulation

,

renal plasma flow

,

pituitary dwarfism

,

,

,

nutrition disorders

,

feeding and eating disorders

,

,

metabolic syndrome

,

obstructive sleep apnea

,

sleep apnea syndromes

,

,

unconsciousness

,

medullary carcinoma

,

,

transient ischemic attack

,

acute coronary syndrome

,

,

,

atherosclerosis

,

biliary tract neoplasms

,

,

,

feeding behavior

,

,

,

,

physiological stress

,

,

bone marrow diseases

,

non-hodgkin lymphoma

,

hodgkin disease

,

sjogren's syndrome

,

gastrointestinal diseases

,

neoplasms by histologic type

,

neoplasms by site

,

nerve tissue neoplasms

,

digestive system diseases

,

intestinal diseases

,

neuroectodermal tumors

,

,

epstein-barr virus infections

,

,

heart valve diseases

,

hemostatic disorders

,

cardiac surgical procedures

,

coagulation protein disorders

,

neurodegenerative diseases

,

positron-emission tomography

lymphoid leukemia

,

squamous cell carcinoma

,

,

b-cell chronic lymphocytic leukemia

,

follicular lymphoma

,

interdigitating dendritic cell sarcoma

,

squamous cell neoplasms

,

adenosquamous carcinoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

philadelphia chromosome

,

myelodysplastic syndromes

,

graft vs host disease

,

gata2 deficiency

,

neoplasm metastasis

,

small cell carcinoma

,

neuroendocrine carcinoma

,

squamous cell carcinoma of head and neck

,

mouth neoplasms

,

,

,

,

,

,

pancreatic neoplasms

,

,

non-hodgkin lymphoma

,

large b-cell lymphoma diffuse

,

ovarian neoplasms

,

non-small-cell lung carcinoma

,

,

serous cystadenocarcinoma

,

b-cell lymphoma

,

myeloid leukemia acute

,

prostatic neoplasms

,

immunoglobulin light-chain amyloidosis

,

,

hematologic neoplasms

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

cholangiocarcinoma

,

malignant mesothelioma

,

,

,

,

colorectal neoplasms

,

pancreatic ductal carcinoma

,

ovarian epithelial carcinoma

,

,

triple negative breast neoplasms

,

myeloid leukemia

,

head and neck neoplasms

,

breast neoplasms

,

multiple myeloma

,

plasma cell neoplasms

1

2

3

4

5

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