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Alexion Pharmaceuticals
Alexion Pharmaceuticals
(ALXN)
Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.
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Marketed Drugs
Therapeutic Areas:
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Classification:
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Include Generics:
Trade Name
Drug Name
Approved
Patent Expires
Indication
Kanuma
Sebelipase alfa
2015-12-08
Inborn errors lipid metabolism
Soliris
Eculizumab
2007-03-16
Paroxysmal hemoglobinuria
,
Myasthenia gravis
,
Atypical hemolytic uremic syndrome
Strensiq
Asfotase alfa
2015-10-23
Hypophosphatasia
Ultomiris
Ravulizumab
2018-12-21
Paroxysmal hemoglobinuria
,
Atypical hemolytic uremic syndrome
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Ravulizumab
healthy volunteers/patients
,
glomerulonephritis
,
lupus nephritis
,
hemolysis
,
neuromyelitis optica
,
thrombotic microangiopathies
,
iga glomerulonephritis
,
syndrome
,
hemolytic-uremic syndrome
,
azotemia
,
chronic renal insufficiency
,
proteinuria
,
vascular diseases
,
covid-19
,
respiratory distress syndrome
,
pneumonia
,
acute lung injury
,
viral pneumonia
,
lung injury
,
newborn respiratory distress syndrome
,
amyotrophic lateral sclerosis
,
motor neuron disease
,
sclerosis
,
recurrence
,
transverse myelitis
,
demyelinating diseases
,
optic neuritis
,
muscle weakness
,
dermatomyositis
,
cardiopulmonary bypass
,
heart diseases
,
kidney transplantation
,
delayed graft function
,
iga vasculitis
,
vasculitis
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
myasthenia gravis
,
atypical hemolytic uremic syndrome
,
adrenal insufficiency
,
anemia
,
pregnancy
Asfotase alfa
hypophosphatasia
Sebelipase alfa
fabry disease
,
cholesterol ester storage disease
,
wolman disease
,
failure to thrive
Eculizumab
healthy volunteers/patients
,
liver diseases
,
end stage liver disease
,
liver failure
,
kidney diseases
,
glomerulonephritis
,
membranoproliferative glomerulonephritis
,
pre-eclampsia
,
hellp syndrome
,
chronic kidney failure
,
vasculitis
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
pregnancy rate
,
sars-cov-2
,
multiple organ failure
,
diabetes mellitus
,
thrombocytopenia
,
complement activation
,
psychology rejection
,
renal insufficiency
,
wounds and injuries
,
reperfusion injury
,
chronic renal insufficiency
,
hemolytic anemia autoimmune
,
death
,
antiphospholipid syndrome
,
macular degeneration
,
geographic atrophy
,
asthma
,
dermatomyositis
,
autoimmune diseases
,
anti-glomerular basement membrane disease
,
myasthenia gravis
,
kidney transplantation
,
muscle weakness
,
vascular diseases
,
thrombotic microangiopathies
,
guillain-barre syndrome
,
delayed graft function
,
anemia
,
escherichia coli infections
,
left ventricular dysfunction
,
ventricular dysfunction
,
shiga-toxigenic escherichia coli
,
leukemia
,
emergencies
,
malignant hypertension
,
hypertensive crisis
,
phenylketonurias
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
hemolysis
,
syndrome
,
hemolytic-uremic syndrome
,
atypical hemolytic uremic syndrome
,
azotemia
,
neuromyelitis optica
,
covid-19
,
optic neuritis
,
coronavirus infections
,
respiratory distress syndrome
,
pneumonia
,
acute lung injury
,
hypophosphatasia
,
severe acute respiratory syndrome
,
viral pneumonia
,
lung injury
,
newborn respiratory distress syndrome
,
coronavirus
,
protein-losing enteropathies
,
intestinal diseases
,
hemophilia b
,
lymphangiectasis
,
intestinal lymphangiectasis
,
pregnancy
,
disease progression
,
intestinal obstruction
,
sinusitis
,
allergic fungal sinusitis
,
rhinosinusitis
,
observation
Danicopan
healthy volunteers/patients
,
hepatic insufficiency
,
renal insufficiency
,
glomerulonephritis
,
membranoproliferative glomerulonephritis
,
geographic atrophy
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
hemolysis
,
anemia
Mycophenolate sodium
neoplasms
,
recurrence
,
precursor cell lymphoblastic leukemia-lymphoma
,
hematologic neoplasms
,
liver transplantation
,
myelodysplastic syndromes
,
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
hodgkin disease
,
lymphoma
,
heart transplantation
,
multiple myeloma
,
bcr-abl positive chronic myelogenous leukemia
,
graft vs host disease
,
liver diseases
,
renal insufficiency
,
aplastic anemia
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
diabetic nephropathies
,
type 1 diabetes mellitus
,
kidney transplantation
,
graft rejection
,
chronic kidney failure
,
psychology rejection
,
kidney diseases
,
cytomegalovirus
,
transplantation
,
diabetes mellitus
,
atopic dermatitis
Benzodiazepine
schizophrenia
Benzimidazole
neoplasms
,
recurrence
,
multiple myeloma
,
hodgkin disease
,
follicular lymphoma
,
mantle-cell lymphoma
,
healthy volunteers/patients
,
breast neoplasms
,
lymphoma
,
b-cell chronic lymphocytic leukemia
,
non-hodgkin lymphoma
,
b-cell lymphoma
,
leukemia
,
lymphoid leukemia
,
large b-cell lymphoma diffuse
,
heartburn
,
hypertension
,
fascioliasis
,
transplantation
,
immunosuppression therapy
,
drug interactions
Cerdulatinib
leukemia
,
b-cell chronic lymphocytic leukemia
,
hodgkin disease
,
b-cell lymphoma
,
t-cell lymphoma cutaneous
,
bronchiolitis obliterans syndrome
,
t-cell lymphoma
,
follicular lymphoma
,
lymphoma
,
large-cell lymphoma anaplastic
,
t-cell lymphoma peripheral
Pexelizumab
coronary artery disease
,
cardiopulmonary bypass
,
coronary artery bypass
Tenofovir
hiv
,
hiv infections
,
hepatitis b
,
chronic hepatitis b
,
hepatitis
,
chronic hepatitis
,
hepatitis a
Choline alfoscerate
general anesthesia
,
neuromuscular blockade
Somatostatin
neuroendocrine carcinoma
,
neoplasm metastasis
,
neuroendocrine tumors
,
acromegaly
,
carcinoid tumor
,
diarrhea
,
serotonin syndrome
Doconexent
healthy volunteers/patients
,
hiv
,
b-cell chronic lymphocytic leukemia
,
obesity
,
overweight
,
immunoglobulin light-chain amyloidosis
,
syndrome
,
lymphoid leukemia
,
residual neoplasm
,
myelodysplastic syndromes
,
preleukemia
,
depression
,
treatment-resistant depressive disorder
,
depressive disorder
,
crohn disease
,
recurrence
,
poems syndrome
,
alzheimer disease
,
frailty
,
leukemia
,
neoplasms
,
precursor cell lymphoblastic leukemia-lymphoma
,
paraproteinemias
,
lymphoma
,
follicular lymphoma
,
amyloidosis
,
smoldering multiple myeloma
,
rheumatoid arthritis
,
arthritis
,
multiple myeloma
,
plasma cell neoplasms
Lornoxicam
t-cell lymphoma
,
t-cell lymphoma peripheral
,
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
breast neoplasms
,
peripheral nervous system diseases
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