Alexion Pharmaceuticals - PharmaKB

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Company ReportsAlexion Pharmaceuticals

Alexion Pharmaceuticals(ALXN)

Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.

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Financial

Marketed Drugs

Clinical Trials

Financial

Stock price

*Currency in USD

Company Revenue

Quarterly

Quarterly

Annual

Annual

Projections

*Quarterly sales USD (in millions)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Kanuma	Sebelipase alfa	2015-12-08		Inborn errors lipid metabolism
Soliris	Eculizumab	2007-03-16		Paroxysmal hemoglobinuria , Atypical hemolytic uremic syndrome
Strensiq	Asfotase alfa	2015-10-23		Hypophosphatasia
Ultomiris	Ravulizumab	2018-12-21		Paroxysmal hemoglobinuria, Atypical hemolytic uremic syndrome

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hypophosphatasia

Sebelipase alfa

,

cholesterol ester storage disease

,

,

failure to thrive

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

end stage liver disease

,

,

kidney transplantation

,

kidney diseases

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

,

,

complement activation

,

chronic renal insufficiency

,

hemolytic anemia autoimmune

,

,

macular degeneration

,

geographic atrophy

,

,

,

,

hemolytic-uremic syndrome

,

atypical hemolytic uremic syndrome

,

myasthenia gravis

,

neuromyelitis optica

,

muscle weakness

,

delayed graft function

,

guillain-barre syndrome

,

left ventricular dysfunction

,

ventricular dysfunction

,

escherichia coli infections

,

shiga-toxigenic escherichia coli

,

phenylketonurias

,

paroxysmal hemoglobinuria

,

,

,

hypophosphatasia

,

respiratory distress syndrome

,

,

acute lung injury

,

viral pneumonia

,

,

newborn respiratory distress syndrome

,

,

disease progression

healthy volunteers/patients

,

,

hepatic insufficiency

,

renal insufficiency

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

macular degeneration

,

geographic atrophy

,

,

paroxysmal hemoglobinuria

,

,

Calcium carbonate

type 2 diabetes mellitus

,

diabetes mellitus

breast neoplasms

respiratory insufficiency

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

,

,

t-cell lymphoma

,

hodgkin disease

,

follicular lymphoma

,

b-cell lymphoma

,

lymphoid leukemia

,

macular degeneration

,

geographic atrophy

,

,

coronary artery disease

,

cardiopulmonary bypass

,

coronary artery bypass

insulin resistance

,

autoimmune diseases of the nervous system

,

,

nervous system malformations

,

kidney diseases

,

,

,

chronic hepatitis d

,

,

herpesviridae infections

,

,

patient acceptance of health care

,

multiple sclerosis

,

,

relapsing-remitting multiple sclerosis

,

,

drug-related side effects and adverse reactions

,

leukoencephalopathies

,

progressive multifocal leukoencephalopathy

,

hepatitis b virus

,

,

,

,

treatment adherence and compliance

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

,

,

,

chronic hepatitis b

,

acquired immunodeficiency syndrome

,

,

chronic hepatitis

,

,

communicable diseases

,

immunologic deficiency syndromes

,

,

,

medication adherence

,

,

substance-related disorders

,

,

patient compliance

,

healthy volunteers/patients

,

,

chronic renal insufficiency

,

renal insufficiency

,

,

persistent infection

,

cognitive dysfunction

,

chronic hepatitis c

,

,

metabolic diseases

,

,

,

kidney transplantation

,

non-hodgkin lymphoma

,

burkitt lymphoma

,

,

,

neurocognitive disorders

,

sleep wake disorders

,

,

,

anxiety disorders

,

opioid-related disorders

,

metabolic bone diseases

,

,

morphine dependence

,

hiv seronegativity

,

,

,

,

recreational drug use

,

hiv seropositivity

,

,

liver cirrhosis

,

,

biliary liver cirrhosis

,

,

,

cardiovascular diseases

,

retinal diseases

,

metabolic syndrome

,

drug interactions

Choline alfoscerate

healthy volunteers/patients

,

hepatolenticular degeneration

1

2

3

4

>

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