Alexion Pharmaceuticals - PharmaKB

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Company ReportsAlexion Pharmaceuticals

Alexion Pharmaceuticals(ALXN)

Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.

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Financial

Marketed Drugs

Clinical Trials

Financial

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*Currency in USD

Company Revenue

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Annual

Annual

Projections

*Quarterly sales USD (in millions)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Kanuma	Sebelipase alfa	2015-12-08		Inborn errors lipid metabolism
Soliris	Eculizumab	2007-03-16		Paroxysmal hemoglobinuria , Myasthenia gravis , Atypical hemolytic uremic syndrome
Strensiq	Asfotase alfa	2015-10-23		Hypophosphatasia
Ultomiris	Ravulizumab	2018-12-21		Paroxysmal hemoglobinuria, Atypical hemolytic uremic syndrome

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hypophosphatasia

Sebelipase alfa

,

cholesterol ester storage disease

,

,

failure to thrive

paroxysmal hemoglobinuria

,

healthy volunteers/patients

,

hepatic insufficiency

,

renal insufficiency

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

geographic atrophy

,

paroxysmal hemoglobinuria

,

,

,

Mycophenolate sodium

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

non-hodgkin lymphoma

,

multiple myeloma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

hodgkin disease

,

t-cell lymphoma peripheral

,

myeloid leukemia

,

lymphoid leukemia

parkinson disease

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

prostatic neoplasms

,

b-cell chronic lymphocytic leukemia

,

,

t-cell lymphoma

,

hodgkin disease

,

follicular lymphoma

,

b-cell lymphoma

,

t-cell lymphoma cutaneous

,

bronchiolitis obliterans syndrome

,

non-hodgkin lymphoma

myocardial infarction

,

,

inferior wall myocardial infarction

,

coronary artery disease

,

cardiopulmonary bypass

,

coronary artery bypass

hepatitis b virus

,

chronic hepatitis b

,

,

,

Choline alfoscerate

healthy volunteers/patients

,

child development

,

,

,

,

male infertility

,

,

esophageal neoplasms

,

,

non-hodgkin lymphoma

,

hodgkin disease

,

food diet and nutrition

,

lymphangioleiomyomatosis

,

,

pharmacokinetics

,

hepatocellular carcinoma

,

liver neoplasms

,

cardiovascular diseases

,

fetal alcohol spectrum disorders

,

cystic fibrosis

,

,

,

,

,

,

,

triple negative breast neoplasms

,

substance-related disorders

,

cognition disorders

,

neurodevelopmental disorders

,

,

marijuana abuse

,

heart valve diseases

,

,

myeloid leukemia acute

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

myeloid leukemia

,

erythroblastic leukemia acute

,

,

,

reperfusion injury

,

myocardial reperfusion injury

,

,

,

exocrine pancreatic insufficiency

,

follicular lymphoma

,

ulcerative colitis

,

knee osteoarthritis

,

,

,

autism spectrum disorder

,

prostatic neoplasms

,

hyperparathyroidism

,

,

,

hypertriglyceridemia

,

non-alcoholic fatty liver disease

,

hepatolenticular degeneration

,

,

prader-willi syndrome

,

primary hyperparathyroidism

,

premature birth

,

,

parathyroid neoplasms

,

coronary artery disease

,

metabolic syndrome

,

ischemic stroke

,

neoplasm metastasis

,

,

,

choline deficiency

,

diabetic neuropathies

,

,

coronary disease

,

multiple myeloma

,

,

,

peripheral nervous system diseases

,

intestinal failure

,

severe acute malnutrition

,

castration-resistant prostatic neoplasms

,

parathyroid diseases

,

general anesthesia

,

hyperhomocysteinemia

,

liver cirrhosis

,

,

,

atherosclerotic plaque

,

,

,

brain hypoxia-ischemia

,

,

iron deficiencies

,

ornithine carbamoyltransferase deficiency disease

,

neuroprotection

,

,

,

,

,

cognitive dysfunction

,

alzheimer disease

,

,

,

,

neuromuscular blockade

,

,

traumatic brain injuries

,

,

,

cerebral infarction

,

,

,

diabetes mellitus

,

wounds and injuries

,

,

,

,

,

,

,

atherosclerosis

,

bipolar disorder

,

optic nerve diseases

,

type 2 diabetes mellitus

,

,

myocardial infarction

,

cesarean section

,

rapid sequence induction and intubation

,

intratracheal intubation

,

chemical and drug induced liver injury

,

postoperative complications

,

muscle hypotonia

,

muscle relaxation

,

respiratory distress syndrome

,

cocaine-related disorders

,

ischemic optic neuropathy

,

,

microvascular angina

,

delayed emergence from anesthesia

,

asperger syndrome

,

,

autistic disorder

,

psychotic disorders

,

alcohol drinking

,

,

,

,

alcoholic hepatitis

,

postoperative pain

,

neural conduction

,

carotid artery diseases

,

acute lung injury

,

newborn respiratory distress syndrome

,

respiratory aspiration

,

,

,

,

heart disease risk factors

,

brain neoplasms

,

breast neoplasms

,

open-angle glaucoma

,

anxiety disorders

,

,

,

patient satisfaction

,

,

,

major depressive disorder

,

depressive disorder

,

,

,

,

prostatic hyperplasia

,

neuroendocrine tumors

,

,

,

,

,

body weight changes

,

,

adrenal insufficiency

,

non-small-cell lung carcinoma

,

infant nutrition disorders

,

alcoholic liver diseases

,

,

pulmonary atelectasis

,

papillary thyroid cancer

,

medullary carcinoma

,

myocardial ischemia

,

coronary stenosis

,

thyroid diseases

,

erdheim-chester disease

,

,

langerhans-cell histiocytosis

,

tourette syndrome

,

myasthenia gravis

,

muscle weakness

,

amphetamine-related disorders

,

,

liver transplantation

,

,

gestational diabetes

,

,

neurodegenerative diseases

,

,

,

carotid stenosis

,

irritable bowel syndrome

,

positron-emission tomography

,

total parenteral nutrition

,

endometrial neoplasms

,

uterine cervical neoplasms

,

lymphatic metastasis

,

muscle strength

,

,

,

uveal neoplasms

,

,

urologic neoplasms

,

,

amyotrophic lateral sclerosis

,

muscle spasticity

,

motor neuron disease

,

hereditary spastic paraplegia

,

,

,

postpartum depression

,

,

hypercholesterolemia

,

,

,

,

communicable diseases

,

,

smoking cessation

,

essential hypertension

,

,

,

neurotoxicity syndromes

,

peripheral nerve injuries

,

nerve degeneration

,

organophosphate poisoning

,

neuroinflammatory diseases

,

obstetrical anesthesia

,

emotional regulation

,

executive function

,

human influenza

,

,

cold temperature

,

gastrointestinal diseases

,

,

,

neuroendocrine carcinoma

,

,

exercise tolerance

,

,

therapeutic chemoembolization

,

underage drinking

,

,

head and neck neoplasms

,

thyroid neoplasms

,

gastrointestinal neoplasms

,

urogenital neoplasms

,

,

,

exfoliation syndrome

,

postoperative care

,

nutrition therapy

,

nutrition assessment

,

pancreatic neoplasms

,

,

tumor microenvironment

chikungunya fever

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