Alexion Pharmaceuticals - PharmaKB

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Company ReportsAlexion Pharmaceuticals

Alexion Pharmaceuticals(ALXN)

Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.

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Financial

Marketed Drugs

Clinical Trials

Financial

Stock price

*Currency in USD

Company Revenue

Quarterly

Quarterly

Annual

Annual

Projections

*Quarterly sales USD (in millions)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Kanuma	Sebelipase alfa	2015-12-08		Inborn errors lipid metabolism
Soliris	Eculizumab	2007-03-16		Paroxysmal hemoglobinuria , Atypical hemolytic uremic syndrome
Strensiq	Asfotase alfa	2015-10-23		Hypophosphatasia
Ultomiris	Ravulizumab	2018-12-21		Paroxysmal hemoglobinuria, Atypical hemolytic uremic syndrome

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hypophosphatasia

Sebelipase alfa

,

cholesterol ester storage disease

,

,

failure to thrive

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

end stage liver disease

,

,

kidney transplantation

,

kidney diseases

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

,

,

complement activation

,

chronic renal insufficiency

,

hemolytic anemia autoimmune

,

,

macular degeneration

,

geographic atrophy

,

,

,

,

hemolytic-uremic syndrome

,

atypical hemolytic uremic syndrome

,

myasthenia gravis

,

neuromyelitis optica

,

muscle weakness

,

delayed graft function

,

guillain-barre syndrome

,

left ventricular dysfunction

,

ventricular dysfunction

,

escherichia coli infections

,

shiga-toxigenic escherichia coli

,

phenylketonurias

,

paroxysmal hemoglobinuria

,

,

,

hypophosphatasia

,

respiratory distress syndrome

,

,

acute lung injury

,

viral pneumonia

,

,

newborn respiratory distress syndrome

,

,

disease progression

healthy volunteers/patients

,

,

hepatic insufficiency

,

renal insufficiency

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

macular degeneration

,

geographic atrophy

,

,

paroxysmal hemoglobinuria

,

,

Mycophenolate sodium

immunosuppression therapy

,

healthy volunteers/patients

,

,

microscopic polyangiitis

,

systemic vasculitis

,

congenital abnormalities

,

urologic diseases

,

chronic kidney failure

,

systemic scleroderma

,

localized scleroderma

,

diffuse scleroderma

,

myelodysplastic syndromes

,

,

,

diabetes mellitus

,

,

,

interstitial lung diseases

,

,

iga glomerulonephritis

,

renal hypertension

,

bullous pemphigoid

,

,

lupus nephritis

,

,

systemic lupus erythematosus

,

type 1 diabetes mellitus

,

neuromyelitis optica

,

,

myasthenia gravis

,

muscle weakness

,

diabetic nephropathies

,

glomerulonephritis

,

multiple sclerosis

,

,

cardiovascular diseases

,

lung transplantation

,

,

pulmonary sarcoidosis

,

membranous glomerulonephritis

,

kidney transplantation

,

kidney diseases

,

liver transplantation

,

heart transplantation

,

renal insufficiency

,

polyomavirus infections

,

corneal transplantation

,

,

,

graft vs host disease

,

hematopoietic stem cell transplantation

Calcium carbonate

,

non-small-cell lung carcinoma

,

Antithrombin iii

healthy volunteers/patients

,

,

non-alcoholic fatty liver disease

,

,

,

hepatic insufficiency

,

chronic renal insufficiency

,

chronic kidney failure

,

cardiovascular diseases

,

alzheimer disease

,

coronary disease

,

acute coronary syndrome

,

cardiac catheterization

,

heart valve prosthesis

,

venous thrombosis

,

,

,

,

non-small-cell lung carcinoma

,

replacement arthroplasty knee

,

,

secondary prevention

,

neoplasm metastasis

,

,

,

ischemic stroke

,

squamous cell carcinoma

,

,

percutaneous coronary intervention

,

replacement arthroplasty hip

,

intracranial sinus thrombosis

,

type 2 diabetes mellitus

,

,

squamous cell carcinoma of head and neck

,

,

,

atrial fibrillation

,

thromboembolism

,

venous thromboembolism

,

renal insufficiency

,

,

myocardial infarction

,

,

cognitive dysfunction

,

replacement arthroplasty

,

heart valve diseases

,

,

,

,

,

cerebral infarction

,

,

cognition disorders

,

coronary artery disease

,

myocardial ischemia

,

transient ischemic attack

,

,

small cell lung carcinoma

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

,

,

t-cell lymphoma

,

hodgkin disease

,

follicular lymphoma

,

b-cell lymphoma

,

lymphoid leukemia

healthy volunteers/patients

coronary artery disease

,

cardiopulmonary bypass

,

coronary artery bypass

Choline alfoscerate

,

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

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