Alexion Pharmaceuticals - PharmaKB

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Company ReportsAlexion Pharmaceuticals

Alexion Pharmaceuticals(ALXN)

Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.

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Financial

Marketed Drugs

Clinical Trials

Financial

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*Currency in USD

Company Revenue

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Annual

Annual

Projections

*Quarterly sales USD (in millions)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Kanuma	Sebelipase alfa	2015-12-08		Inborn errors lipid metabolism
Soliris	Eculizumab	2007-03-16		Paroxysmal hemoglobinuria , Myasthenia gravis , Atypical hemolytic uremic syndrome
Strensiq	Asfotase alfa	2015-10-23		Hypophosphatasia
Ultomiris	Ravulizumab	2018-12-21		Paroxysmal hemoglobinuria, Atypical hemolytic uremic syndrome

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hypophosphatasia

Sebelipase alfa

,

cholesterol ester storage disease

,

,

failure to thrive

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

end stage liver disease

,

,

atypical hemolytic uremic syndrome

,

,

kidney transplantation

,

kidney diseases

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

,

,

complement activation

,

psychology rejection

,

chronic renal insufficiency

,

hemolytic anemia autoimmune

,

,

macular degeneration

,

geographic atrophy

,

,

,

hemolytic-uremic syndrome

,

myasthenia gravis

,

neuromyelitis optica

,

muscle weakness

,

delayed graft function

,

guillain-barre syndrome

,

left ventricular dysfunction

,

ventricular dysfunction

,

escherichia coli infections

,

shiga-toxigenic escherichia coli

,

phenylketonurias

,

paroxysmal hemoglobinuria

,

,

,

respiratory distress syndrome

,

,

acute lung injury

,

hypophosphatasia

,

severe acute respiratory syndrome

,

viral pneumonia

,

,

newborn respiratory distress syndrome

,

,

disease progression

,

healthy volunteers/patients

,

hepatic insufficiency

,

renal insufficiency

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

geographic atrophy

,

paroxysmal hemoglobinuria

,

,

,

Mycophenolate sodium

immunosuppression therapy

,

healthy volunteers/patients

,

microscopic polyangiitis

,

congenital abnormalities

,

chronic kidney failure

,

systemic scleroderma

,

myelodysplastic syndromes

,

,

,

,

,

interstitial lung diseases

,

localized scleroderma

,

diffuse scleroderma

,

,

iga glomerulonephritis

,

renal hypertension

,

diabetes mellitus

,

bullous pemphigoid

,

,

lupus nephritis

,

,

systemic lupus erythematosus

,

type 1 diabetes mellitus

,

neuromyelitis optica

,

,

myasthenia gravis

,

diabetic nephropathies

,

multiple sclerosis

,

cardiovascular diseases

,

lung transplantation

,

,

pulmonary sarcoidosis

,

membranous glomerulonephritis

,

kidney transplantation

,

liver transplantation

,

heart transplantation

,

kidney diseases

,

renal insufficiency

,

polyomavirus infections

,

corneal transplantation

,

,

,

graft vs host disease

,

hematopoietic stem cell transplantation

drug-related side effects and adverse reactions

,

healthy volunteers/patients

,

sleep initiation and maintenance disorders

,

,

lennox gastaut syndrome

,

,

treatment-resistant schizophrenia

,

myoclonic epilepsies

,

,

generalized epilepsy

,

epilepsia partialis continua

,

psychotic disorders

,

schizophrenia spectrum and other psychotic disorders

,

,

partial epilepsies

,

drug resistant epilepsy

,

status epilepticus

pharmacokinetics

,

drug interactions

b-cell chronic lymphocytic leukemia

,

,

t-cell lymphoma

,

hodgkin disease

,

follicular lymphoma

,

b-cell lymphoma

,

t-cell lymphoma cutaneous

,

bronchiolitis obliterans syndrome

,

non-hodgkin lymphoma

myocardial infarction

,

,

inferior wall myocardial infarction

,

coronary artery disease

,

,

,

acquired immunodeficiency syndrome

,

,

cognitive dysfunction

Choline alfoscerate

myeloid leukemia acute

,

precursor cell lymphoblastic leukemia-lymphoma

,

non-hodgkin lymphoma

,

hematologic neoplasms

,

graft vs host disease

,

myelodysplastic syndromes

,

multiple myeloma

,

follicular lymphoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

,

,

,

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