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Company ReportsAlexion Pharmaceuticals

Alexion Pharmaceuticals(ALXN)

Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.

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Marketed Drugs

Clinical Trials

Financial

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Company Revenue

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Kanuma	Sebelipase alfa	2015-12-08		Inborn errors lipid metabolism
Soliris	Eculizumab	2007-03-16		Paroxysmal hemoglobinuria , Myasthenia gravis , Atypical hemolytic uremic syndrome
Strensiq	Asfotase alfa	2015-10-23		Hypophosphatasia
Ultomiris	Ravulizumab	2018-12-21		Paroxysmal hemoglobinuria, Atypical hemolytic uremic syndrome

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hypophosphatasia

Sebelipase alfa

,

cholesterol ester storage disease

,

,

failure to thrive

healthy volunteers/patients

,

,

end stage liver disease

,

,

kidney diseases

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

,

chronic kidney failure

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

,

multiple organ failure

,

diabetes mellitus

,

thrombocytopenia

,

complement activation

,

psychology rejection

,

renal insufficiency

,

wounds and injuries

,

reperfusion injury

,

chronic renal insufficiency

,

hemolytic anemia autoimmune

,

,

antiphospholipid syndrome

,

macular degeneration

,

geographic atrophy

,

,

dermatomyositis

,

autoimmune diseases

,

anti-glomerular basement membrane disease

,

myasthenia gravis

,

kidney transplantation

,

muscle weakness

,

vascular diseases

,

thrombotic microangiopathies

,

guillain-barre syndrome

,

delayed graft function

,

,

escherichia coli infections

,

left ventricular dysfunction

,

ventricular dysfunction

,

shiga-toxigenic escherichia coli

,

,

,

malignant hypertension

,

hypertensive crisis

,

phenylketonurias

,

paroxysmal hemoglobinuria

,

,

,

,

hemolytic-uremic syndrome

,

atypical hemolytic uremic syndrome

,

,

neuromyelitis optica

,

,

,

coronavirus infections

,

respiratory distress syndrome

,

,

acute lung injury

,

hypophosphatasia

,

severe acute respiratory syndrome

,

viral pneumonia

,

,

newborn respiratory distress syndrome

,

,

protein-losing enteropathies

,

intestinal diseases

,

,

lymphangiectasis

,

intestinal lymphangiectasis

,

,

disease progression

,

intestinal obstruction

,

,

allergic fungal sinusitis

,

,

healthy volunteers/patients

,

hepatic insufficiency

,

renal insufficiency

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

geographic atrophy

,

paroxysmal hemoglobinuria

,

,

,

healthy volunteers/patients

,

type 2 diabetes mellitus

,

,

,

,

non-small-cell lung carcinoma

,

,

respiratory syncytial virus infections

,

brain neoplasms

,

central nervous system neoplasms

,

,

glucose metabolism disorders

,

metabolic diseases

,

alzheimer disease

,

huntington disease

,

thyroid neoplasms

,

,

sickle cell anemia

,

atopic dermatitis

,

colorectal neoplasms

,

anxiety disorders

,

prostatic neoplasms

,

breast neoplasms

,

,

adenocarcinoma of lung

,

generalized anxiety disorder

,

reflex epilepsy

,

bipolar disorder

,

diabetes mellitus

,

,

status epilepticus

,

critical illness

,

,

psychomotor agitation

,

post-traumatic stress disorders

,

executive function

,

,

partial epilepsies

,

generalized epilepsy

,

complex partial epilepsy

,

,

insulin resistance

,

metabolic syndrome

,

,

major depressive disorder

,

depressive disorder

,

psychotic disorders

,

gastrointestinal endoscopy

,

hyperlipidemias

,

psoriatic arthritis

,

,

,

intestinal volvulus

,

large b-cell lymphoma diffuse

,

b-cell chronic lymphocytic leukemia

,

non-hodgkin lymphoma

,

,

follicular lymphoma

,

,

lymphoid leukemia

,

b-cell chronic lymphocytic leukemia

,

,

t-cell lymphoma

,

hodgkin disease

,

follicular lymphoma

,

b-cell lymphoma

,

t-cell lymphoma cutaneous

,

bronchiolitis obliterans syndrome

,

non-hodgkin lymphoma

myocardial infarction

,

,

inferior wall myocardial infarction

,

coronary artery disease

,

cardiopulmonary bypass

,

coronary artery bypass

Choline alfoscerate

healthy volunteers/patients

,

child development

,

,

,

,

male infertility

,

,

esophageal neoplasms

,

,

non-hodgkin lymphoma

,

hodgkin disease

,

food diet and nutrition

,

lymphangioleiomyomatosis

,

,

pharmacokinetics

,

hepatocellular carcinoma

,

liver neoplasms

,

fetal alcohol spectrum disorders

,

cystic fibrosis

,

cardiovascular diseases

,

,

,

,

,

,

triple negative breast neoplasms

,

substance-related disorders

,

follicular lymphoma

,

cognition disorders

,

neurodevelopmental disorders

,

,

marijuana abuse

,

heart valve diseases

,

,

myeloid leukemia acute

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

myeloid leukemia

,

erythroblastic leukemia acute

,

,

,

reperfusion injury

,

myocardial reperfusion injury

,

,

,

exocrine pancreatic insufficiency

,

ulcerative colitis

,

knee osteoarthritis

,

,

autism spectrum disorder

,

prostatic neoplasms

,

hyperparathyroidism

,

,

,

hypertriglyceridemia

,

non-alcoholic fatty liver disease

,

prader-willi syndrome

,

hepatolenticular degeneration

,

,

primary hyperparathyroidism

,

premature birth

,

,

parathyroid neoplasms

,

coronary artery disease

,

metabolic syndrome

,

ischemic stroke

,

neoplasm metastasis

,

,

,

choline deficiency

,

diabetic neuropathies

,

,

coronary disease

,

multiple myeloma

,

,

,

peripheral nervous system diseases

,

intestinal failure

,

severe acute malnutrition

,

castration-resistant prostatic neoplasms

,

parathyroid diseases

,

general anesthesia

,

hyperhomocysteinemia

,

liver cirrhosis

,

,

,

atherosclerotic plaque

,

,

,

brain hypoxia-ischemia

,

,

iron deficiencies

,

ornithine carbamoyltransferase deficiency disease

,

neuroprotection

,

,

,

,

,

cognitive dysfunction

,

alzheimer disease

,

,

,

,

neuromuscular blockade

,

,

traumatic brain injuries

,

,

,

cerebral infarction

,

,

,

wounds and injuries

,

,

,

,

,

,

,

atherosclerosis

,

bipolar disorder

,

optic nerve diseases

,

type 2 diabetes mellitus

,

,

myocardial infarction

,

cesarean section

,

rapid sequence induction and intubation

,

intratracheal intubation

,

chemical and drug induced liver injury

,

postoperative complications

,

muscle hypotonia

,

muscle relaxation

,

respiratory distress syndrome

,

cocaine-related disorders

,

ischemic optic neuropathy

,

,

microvascular angina

,

delayed emergence from anesthesia

,

asperger syndrome

,

,

autistic disorder

,

psychotic disorders

,

alcohol drinking

,

,

,

,

alcoholic hepatitis

,

postoperative pain

,

neural conduction

,

acute lung injury

,

newborn respiratory distress syndrome

,

respiratory aspiration

,

,

,

,

heart disease risk factors

,

brain neoplasms

,

breast neoplasms

,

diabetes mellitus

,

open-angle glaucoma

,

anxiety disorders

,

,

,

,

patient satisfaction

,

,

,

major depressive disorder

,

depressive disorder

,

,

,

,

prostatic hyperplasia

,

neuroendocrine tumors

,

,

,

,

,

body weight changes

,

,

adrenal insufficiency

,

non-small-cell lung carcinoma

,

infant nutrition disorders

,

alcoholic liver diseases

,

,

pulmonary atelectasis

,

papillary thyroid cancer

,

medullary carcinoma

,

myocardial ischemia

,

coronary stenosis

,

thyroid diseases

,

erdheim-chester disease

,

,

langerhans-cell histiocytosis

,

tourette syndrome

,

myasthenia gravis

,

muscle weakness

,

amphetamine-related disorders

,

,

liver transplantation

,

,

gestational diabetes

,

,

neurodegenerative diseases

,

,

,

carotid stenosis

,

irritable bowel syndrome

,

positron-emission tomography

,

total parenteral nutrition

,

endometrial neoplasms

,

uterine cervical neoplasms

,

muscle strength

,

,

,

uveal neoplasms

,

,

urologic neoplasms

,

,

amyotrophic lateral sclerosis

,

muscle spasticity

,

motor neuron disease

,

hereditary spastic paraplegia

,

,

,

postpartum depression

,

,

hypercholesterolemia

,

,

,

,

smoking cessation

,

essential hypertension

,

,

,

neurotoxicity syndromes

,

peripheral nerve injuries

,

nerve degeneration

,

organophosphate poisoning

,

neuroinflammatory diseases

,

obstetrical anesthesia

,

emotional regulation

,

executive function

,

human influenza

,

,

cold temperature

,

gastrointestinal diseases

,

,

,

neuroendocrine carcinoma

,

,

exercise tolerance

,

,

therapeutic chemoembolization

,

underage drinking

,

,

head and neck neoplasms

,

thyroid neoplasms

,

gastrointestinal neoplasms

,

urogenital neoplasms

,

,

,

exfoliation syndrome

,

postoperative care

,

nutrition therapy

,

nutrition assessment

,

pancreatic neoplasms

,

,

tumor microenvironment

,

chronic obstructive pulmonary disease

,

prenatal nutritional physiological phenomena

,

,

pheochromocytoma

,

,

,

malignant carcinoid syndrome

,

carcinoid heart disease

,

serotonin syndrome

,

,

liver neoplasms

,

neoplasm metastasis

,

neuroendocrine tumors

,

carcinoid tumor

,

,

neuroendocrine carcinoma

b-cell chronic lymphocytic leukemia

,

reactive arthritis

,

b-cell lymphoma marginal zone

,

hairy cell leukemia

,

b-cell lymphoma

,

follicular lymphoma

,

large b-cell lymphoma diffuse

,

non-hodgkin lymphoma

,

,

,

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