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Alexion Pharmaceuticals
Alexion Pharmaceuticals
(ALXN)
Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.
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Revenue by Drug
Marketed Drugs
Therapeutic Areas:
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Classification:
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Include Generics:
Trade Name
Drug Name
Approved
Patent Expires
Indication
Kanuma
Sebelipase alfa
2015-12-08
Inborn errors lipid metabolism
Soliris
Eculizumab
2007-03-16
Paroxysmal hemoglobinuria
,
Myasthenia gravis
,
Atypical hemolytic uremic syndrome
Strensiq
Asfotase alfa
2015-10-23
Hypophosphatasia
Ultomiris
Ravulizumab
2018-12-21
Paroxysmal hemoglobinuria
,
Atypical hemolytic uremic syndrome
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Ravulizumab
healthy volunteers/patients
,
lupus nephritis
,
hemolysis
,
myasthenia gravis
,
kidney diseases
,
neuromyelitis optica
,
muscle weakness
,
vascular diseases
,
thrombotic microangiopathies
,
iga glomerulonephritis
,
syndrome
,
hemolytic-uremic syndrome
,
atypical hemolytic uremic syndrome
,
nephritis
,
azotemia
,
covid-19
,
respiratory distress syndrome
,
pneumonia
,
acute lung injury
,
viral pneumonia
,
lung injury
,
newborn respiratory distress syndrome
,
amyotrophic lateral sclerosis
,
motor neuron disease
,
sclerosis
,
dermatomyositis
,
chronic renal insufficiency
,
cardiopulmonary bypass
,
heart diseases
,
kidney transplantation
,
delayed graft function
,
iga vasculitis
,
vasculitis
,
purpura
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
pregnancy
Asfotase alfa
hypophosphatasia
Sebelipase alfa
fabry disease
,
cholesterol ester storage disease
,
wolman disease
,
failure to thrive
Eculizumab
glomerulonephritis
,
membranoproliferative glomerulonephritis
,
liver diseases
,
end stage liver disease
,
azotemia
,
kidney transplantation
,
kidney diseases
,
vasculitis
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
pre-eclampsia
,
pregnancy rate
,
hellp syndrome
,
complement activation
,
chronic renal insufficiency
,
hemolytic anemia autoimmune
,
death
,
macular degeneration
,
geographic atrophy
,
asthma
,
hemolysis
,
syndrome
,
hemolytic-uremic syndrome
,
atypical hemolytic uremic syndrome
,
myasthenia gravis
,
neuromyelitis optica
,
muscle weakness
,
delayed graft function
,
guillain-barre syndrome
,
left ventricular dysfunction
,
ventricular dysfunction
,
escherichia coli infections
,
shiga-toxigenic escherichia coli
,
phenylketonurias
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
covid-19
,
hypophosphatasia
,
respiratory distress syndrome
,
pneumonia
,
acute lung injury
,
viral pneumonia
,
lung injury
,
newborn respiratory distress syndrome
,
pregnancy
,
disease progression
Danicopan
healthy volunteers/patients
,
liver diseases
,
hepatic insufficiency
,
renal insufficiency
,
glomerulonephritis
,
membranoproliferative glomerulonephritis
,
macular degeneration
,
geographic atrophy
,
atrophy
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
hemolysis
Mycophenolate sodium
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
neoplasms
,
lymphoma
,
hematologic neoplasms
,
liver transplantation
,
myelodysplastic syndromes
,
heart transplantation
,
non-hodgkin lymphoma
,
multiple myeloma
,
b-cell chronic lymphocytic leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
hodgkin disease
,
preleukemia
,
liver diseases
,
anemia
,
aplastic anemia
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
diabetic nephropathies
,
type 1 diabetes mellitus
,
kidney transplantation
,
graft rejection
,
chronic kidney failure
,
kidney diseases
,
cytomegalovirus
,
death
,
transplantation
,
diabetes mellitus
Mycophenolic acid
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
neoplasms
,
lymphoma
,
hematologic neoplasms
,
liver transplantation
,
myelodysplastic syndromes
,
heart transplantation
,
non-hodgkin lymphoma
,
multiple myeloma
,
b-cell chronic lymphocytic leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
hodgkin disease
,
preleukemia
,
liver diseases
,
anemia
,
aplastic anemia
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
diabetic nephropathies
,
type 1 diabetes mellitus
,
kidney transplantation
,
graft rejection
,
chronic kidney failure
,
kidney diseases
,
cytomegalovirus
,
death
,
transplantation
,
diabetes mellitus
Iron dextran
iron overload
,
beta-thalassemia
,
thalassemia
,
metabolic diseases
,
metabolic syndrome
,
iron metabolism disorders
,
hemosiderosis
Cerdulatinib
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
leukemia
,
hodgkin disease
,
b-cell lymphoma
,
lymphoid leukemia
,
vitiligo
,
lymphoma
,
t-cell lymphoma
,
follicular lymphoma
,
large-cell lymphoma anaplastic
,
t-cell lymphoma peripheral
Lampalizumab
leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
philadelphia chromosome
,
lymphoid leukemia
Pexelizumab
coronary artery disease
,
cardiopulmonary bypass
,
coronary artery bypass
Tenofovir
hepatitis c
,
virus diseases
,
breast feeding
,
pregnancy
,
hiv infections
,
acquired immunodeficiency syndrome
,
infections
,
communicable diseases
,
immunologic deficiency syndromes
,
hiv
,
sarcoma
,
kaposi sarcoma
,
hepatitis b
,
hepatitis
,
hepatitis a
,
liver cirrhosis
,
fibrosis
,
biliary liver cirrhosis
,
lipodystrophy
Choline alfoscerate
hemophilia a
Doconexent
melanoma
,
prostatic neoplasms
,
renal cell carcinoma
,
breast neoplasms
,
ovarian neoplasms
,
pancreatic neoplasms
,
head and neck neoplasms
,
postmenopausal osteoporosis
,
carcinoma
,
colorectal neoplasms
,
neoplasms
,
non-hodgkin lymphoma
,
multiple myeloma
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
esophageal neoplasms
,
adenocarcinoma
,
obesity
,
overweight
,
mantle-cell lymphoma
,
lung neoplasms
,
non-small-cell lung carcinoma
,
lymphoma
,
depression
,
major depressive disorder
,
depressive disorder
,
hodgkin disease
,
osteoporosis
Lornoxicam
multiple myeloma
,
b-cell chronic lymphocytic leukemia
,
plasma cell neoplasms
,
hodgkin disease
,
lymphoma
,
breast neoplasms
,
mucinous adenocarcinoma
,
ductal carcinoma breast
,
inflammatory breast neoplasms
,
non-hodgkin lymphoma
,
mantle-cell lymphoma
,
carcinoma
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
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