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Alexion Pharmaceuticals
Alexion Pharmaceuticals
(ALXN)
Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.
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Clinical Trials
Financial
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Revenue by Drug
Marketed Drugs
Therapeutic Areas:
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Classification:
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Include Generics:
Trade Name
Drug Name
Approved
Patent Expires
Indication
Kanuma
Sebelipase alfa
2015-12-08
Inborn errors lipid metabolism
Soliris
Eculizumab
2007-03-16
Paroxysmal hemoglobinuria
,
Atypical hemolytic uremic syndrome
Strensiq
Asfotase alfa
2015-10-23
Hypophosphatasia
Ultomiris
Ravulizumab
2018-12-21
Paroxysmal hemoglobinuria
,
Atypical hemolytic uremic syndrome
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Ravulizumab
healthy volunteers/patients
,
lupus nephritis
,
nephritis
,
hemolysis
,
neuromyelitis optica
,
myasthenia gravis
,
vascular diseases
,
thrombotic microangiopathies
,
kidney diseases
,
syndrome
,
muscle weakness
,
hemolytic-uremic syndrome
,
atypical hemolytic uremic syndrome
,
iga glomerulonephritis
,
azotemia
,
covid-19
,
respiratory distress syndrome
,
pneumonia
,
acute lung injury
,
viral pneumonia
,
lung injury
,
newborn respiratory distress syndrome
,
amyotrophic lateral sclerosis
,
motor neuron disease
,
sclerosis
,
dermatomyositis
,
chronic renal insufficiency
,
cardiopulmonary bypass
,
heart diseases
,
kidney transplantation
,
delayed graft function
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
pregnancy
Asfotase alfa
hypophosphatasia
Sebelipase alfa
fabry disease
,
cholesterol ester storage disease
,
wolman disease
,
failure to thrive
Eculizumab
glomerulonephritis
,
membranoproliferative glomerulonephritis
,
liver diseases
,
end stage liver disease
,
azotemia
,
kidney transplantation
,
kidney diseases
,
vasculitis
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
pre-eclampsia
,
pregnancy rate
,
hellp syndrome
,
complement activation
,
chronic renal insufficiency
,
hemolytic anemia autoimmune
,
death
,
macular degeneration
,
geographic atrophy
,
asthma
,
hemolysis
,
syndrome
,
hemolytic-uremic syndrome
,
atypical hemolytic uremic syndrome
,
myasthenia gravis
,
neuromyelitis optica
,
muscle weakness
,
delayed graft function
,
guillain-barre syndrome
,
left ventricular dysfunction
,
ventricular dysfunction
,
escherichia coli infections
,
shiga-toxigenic escherichia coli
,
phenylketonurias
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
covid-19
,
hypophosphatasia
,
respiratory distress syndrome
,
pneumonia
,
acute lung injury
,
viral pneumonia
,
lung injury
,
newborn respiratory distress syndrome
,
pregnancy
,
disease progression
Danicopan
healthy volunteers/patients
,
liver diseases
,
hepatic insufficiency
,
renal insufficiency
,
glomerulonephritis
,
membranoproliferative glomerulonephritis
,
macular degeneration
,
geographic atrophy
,
atrophy
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
hemolysis
Mycophenolate sodium
myeloproliferative disorders
,
primary myelofibrosis
,
hematologic neoplasms
,
neoplasm metastasis
,
anemia
,
aplastic anemia
,
leukemia
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
lymphoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
b-cell chronic lymphocytic leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
myelomonocytic leukemia chronic
,
prolymphocytic leukemia
,
myeloid leukemia
,
myelomonocytic leukemia juvenile
,
lymphoid leukemia
,
graft vs host disease
,
bronchiolitis obliterans syndrome
Calcium carbonate
smallpox
Albumin
cocaine-related disorders
,
addictive behavior
,
neutropenia
,
chemotherapy-induced febrile neutropenia
,
breast neoplasms
Antithrombin iii
thrombosis
,
liver cirrhosis
,
venous thrombosis
,
fibrosis
,
cardiopulmonary bypass
,
coronary artery bypass
,
cardiac surgical procedures
,
covid-19
,
infections
,
communicable diseases
,
antithrombin iii deficiency
Vitamin e
muscular atrophy
,
spinal muscular atrophy
,
neoplasms
,
atherosclerosis
Cerdulatinib
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
leukemia
,
lymphoma
,
t-cell lymphoma
,
hodgkin disease
,
follicular lymphoma
,
b-cell lymphoma
,
lymphoid leukemia
Lampalizumab
multiple myeloma
,
plasma cell neoplasms
Pexelizumab
myocardial infarction
,
infarction
,
inferior wall myocardial infarction
,
coronary artery disease
Tenofovir
insulin resistance
,
autoimmune diseases of the nervous system
,
syndrome
,
nervous system malformations
,
kidney diseases
,
recurrence
,
liver diseases
,
chronic hepatitis d
,
hepatitis d
,
herpesviridae infections
,
lipodystrophy
,
patient acceptance of health care
,
multiple sclerosis
,
fatigue
,
relapsing-remitting multiple sclerosis
,
sclerosis
,
drug-related side effects and adverse reactions
,
leukoencephalopathies
,
progressive multifocal leukoencephalopathy
,
hepatitis b virus
,
pregnancy
,
drug misuse
,
virus diseases
,
treatment adherence and compliance
,
carcinoma
,
hepatocellular carcinoma
,
liver neoplasms
,
breast feeding
,
hiv infections
,
hepatitis b
,
hepatitis
,
hiv
,
chronic hepatitis b
,
acquired immunodeficiency syndrome
,
hepatitis a
,
chronic hepatitis
,
infections
,
communicable diseases
,
immunologic deficiency syndromes
,
coinfection
,
hiv-1
,
medication adherence
,
hepatitis c
,
substance-related disorders
,
tuberculosis
,
patient compliance
,
healthy volunteers/patients
,
osteoporosis
,
chronic renal insufficiency
,
renal insufficiency
,
lymphoma
,
persistent infection
,
cognitive dysfunction
,
chronic hepatitis c
,
neoplasms
,
metabolic diseases
,
crush injuries
,
menopause
,
kidney transplantation
,
non-hodgkin lymphoma
,
burkitt lymphoma
,
viremia
,
herpes simplex
,
neurocognitive disorders
,
sleep wake disorders
,
dyssomnias
,
parasomnias
,
anxiety disorders
,
opioid-related disorders
,
metabolic bone diseases
,
bone diseases
,
morphine dependence
,
hiv seronegativity
,
sarcoma
,
kaposi sarcoma
,
harm reduction
,
recreational drug use
,
hiv seropositivity
,
aging
,
liver cirrhosis
,
fibrosis
,
biliary liver cirrhosis
,
inflammation
,
job syndrome
,
cardiovascular diseases
,
retinal diseases
,
metabolic syndrome
,
drug interactions
Choline alfoscerate
healthy volunteers/patients
,
hepatolenticular degeneration
1
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3
4
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