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Acacia Pharma

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Barhemsys	Amisulpride	2020-02-26	2031-2038	—
Byfavo	Remimazolam	2020-10-06	2027-2033	Conscious sedation

Clinical Trials

Therapeutic Areas:

All

Classification:

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Approval:

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Status:

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Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

chronic kidney failure

,

postoperative nausea and vomiting

,

,

endometrial neoplasms

,

uterine cervical neoplasms

,

,

myeloid leukemia acute

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

mantle-cell lymphoma

,

ovarian neoplasms

,

aids-related lymphoma

,

central nervous system neoplasms

,

,

rheumatoid arthritis

,

,

,

,

stem cell transplantation

,

systemic scleroderma

,

,

interstitial lung diseases

,

localized scleroderma

,

diffuse scleroderma

,

behcet syndrome

,

reactive arthritis

,

,

immunoblastic lymphadenopathy

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

non-hodgkin lymphoma

,

triple negative breast neoplasms

,

inflammatory breast neoplasms

,

lupus nephritis

,

,

colorectal neoplasms

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

patient preference

,

membranous glomerulonephritis

,

systemic lupus erythematosus

,

breast neoplasms

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

follicular lymphoma

,

,

postmenopausal osteoporosis

Bos taurus adrenal cortex corticosteroids

healthy volunteers/patients

appendiceal neoplasms

,

cystadenocarcinoma

,

neoplasms by histologic type

,

sezary syndrome

,

,

hematologic diseases

,

chromosome aberrations

,

female genital neoplasms

,

castration-resistant prostatic neoplasms

,

leukemia myeloid chronic atypical bcr-abl negative

,

,

,

cutaneous malignant melanoma

,

deltaretrovirus infections

,

htlv-i infections

,

composite lymphoma

,

pelvic neoplasms

,

abdominal neoplasms

,

urogenital neoplasms

,

gastrointestinal stromal tumors

,

liver cirrhosis

,

squamous cell carcinoma of head and neck

,

,

plasmablastic lymphoma

,

invasive hydatidiform mole

,

,

adult t-cell leukemia-lymphoma

,

non-small-cell lung carcinoma

,

aids-related lymphoma

,

myeloid leukemia chronic-phase

,

thyroid neoplasms

,

head and neck neoplasms

,

intestinal neoplasms

,

primary effusion lymphoma

,

,

gastrointestinal neoplasms

,

germ cell and embryonal neoplasms

,

,

desmoplastic small round cell tumor

,

thyroid diseases

,

cholangiocarcinoma

,

squamous cell carcinoma

,

ductal carcinoma

,

t-cell lymphoma cutaneous

,

,

urologic neoplasms

,

,

primitive neuroectodermal tumors

,

primary myelofibrosis

,

uterine cervical neoplasms

,

salivary gland neoplasms

,

breast carcinoma in situ

,

anaplastic thyroid carcinoma

,

thymus neoplasms

,

embryonal rhabdomyosarcoma

,

thrombocytopenia

,

healthy volunteers/patients

,

hypersensitivity

,

intestinal diseases

,

hairy cell leukemia

,

lymphomatoid granulomatosis

,

mycosis fungoides

,

,

myeloid leukemia accelerated phase

,

plasma cell leukemia

,

adenoid cystic carcinoma

,

,

,

carcinoma in situ

,

endocrine gland neoplasms

,

bile duct neoplasms

,

esophageal squamous cell carcinoma

,

graft vs host disease

,

,

alveolar rhabdomyosarcoma

,

neurotoxicity syndromes

,

,

,

neuroendocrine tumors

,

nervous system neoplasms

,

,

intraocular lymphoma

,

castleman disease

,

,

phenylketonurias

,

,

hereditary breast and ovarian cancer syndrome

,

adenomyoepithelioma

,

testicular neoplasms

,

,

neuroepithelial neoplasms

,

islet cell adenoma

,

,

pancreatic ductal carcinoma

,

,

chemotherapy-related cognitive impairment

,

immunoglobulin light-chain amyloidosis

,

,

renal insufficiency

,

human herpesvirus 8

,

cortical blindness

,

blastic plasmacytoid dendritic cell neoplasm

,

antineoplastic combined chemotherapy protocols

,

paranasal sinus neoplasms

,

febrile neutropenia

,

neoplasms by site

,

thromboembolism

,

,

,

gene rearrangement

,

prolymphocytic leukemia t-cell

,

,

,

cardiovascular abnormalities

,

prosthesis failure

,

,

essential thrombocythemia

,

polycythemia vera

,

diffuse intrinsic pontine glioma

,

hemolytic anemia autoimmune

,

hemolytic anemia

,

,

experimental neoplasms

,

fibrous tissue neoplasms

,

optic nerve glioma

,

oligodendroglioma

,

disease progression

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

,

,

zollinger-ellison syndrome

,

post-traumatic stress disorders

,

,

,

,

adenoviridae infections

,

respiratory aspiration

,

mouth neoplasms

,

,

large cell carcinoma

,

vaginal neoplasms

,

vulvar neoplasms

,

endometrial stromal sarcoma

,

minimally invasive surgical procedures

,

cystic fibrosis

,

ovarian neoplasms

,

neoplasm metastasis

,

,

,

stomach neoplasms

,

ovarian epithelial carcinoma

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

,

,

erythroblastic leukemia acute

,

inflammatory breast neoplasms

,

,

megakaryoblastic leukemia acute

,

prostatic neoplasms

,

male breast neoplasms

,

kidney neoplasms

,

,

,

endometrial neoplasms

,

fallopian tube neoplasms

,

bcr-abl positive chronic myelogenous leukemia

,

esophageal neoplasms

,

,

congenital abnormalities

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

myeloproliferative disorders

,

b-cell chronic lymphocytic leukemia

,

transitional cell carcinoma

,

myelomonocytic leukemia chronic

,

cardiovascular diseases

,

small cell lung carcinoma

,

,

colorectal neoplasms

,

,

pancreatic neoplasms

,

endometrioid carcinoma

,

hematologic neoplasms

,

,

b-cell lymphoma marginal zone

,

refractory anemia with excess of blasts

,

large-cell lymphoma immunoblastic

,

,

,

,

basophilic leukemia acute

,

malignant fibrous histiocytoma

,

neoadjuvant therapy

,

,

myelodysplastic-myeloproliferative diseases

,

t-cell leukemia

,

eosinophilic leukemia acute

,

acinar cell carcinoma

,

ureteral neoplasms

,

serous cystadenocarcinoma

,

renal cell carcinoma

,

peritoneal neoplasms

,

malignant mesothelioma

,

,

waldenstrom macroglobulinemia

,

extranodal nk-t-cell lymphoma

,

mucinous cystadenocarcinoma

,

ductal carcinoma breast

,

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

mucinous adenocarcinoma

,

hemangiosarcoma

,

neuroectodermal tumors

,

synovial sarcoma

,

neurofibrosarcoma

,

refractory anemia

,

urethral neoplasms

,

primitive neuroectodermal tumors peripheral

,

benign fibrous histiocytoma

,

ganglioneuroblastoma

,

brain neoplasms

,

myelomonocytic leukemia juvenile

,

nerve sheath neoplasms

,

,

adrenocortical carcinoma

,

drug-related side effects and adverse reactions

,

,

eyelid neoplasms

,

residual neoplasm

,

hypereosinophilic syndrome

,

,

,

acquired immunodeficiency syndrome

,

clear cell adenocarcinoma

,

left ventricular dysfunction

,

,

central nervous system neoplasms

,

lobular carcinoma

,

,

,

dermatofibrosarcoma

,

uterine neoplasms

,

reactive arthritis

,

myeloid sarcoma

,

gallbladder neoplasms

,

clear cell sarcoma

,

induction chemotherapy

,

chemotherapy-induced febrile neutropenia

,

,

connective and soft tissue neoplasms

,

epstein-barr virus infections

,

,

colonic neoplasms

,

b-cell leukemia

,

adjuvant chemotherapy

,

,

ventricular dysfunction

,

solitary fibrous tumors

,

hemangiopericytoma

,

pheochromocytoma

,

lymphadenopathy

,

pathologic complete response

,

alveolar soft part sarcoma

,

rectal neoplasms

,

adenosquamous carcinoma

,

interdigitating dendritic cell sarcoma

,

lymphatic diseases

,

hemophagocytic lymphohistiocytosis

,

pulmonary blastoma

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

,

postoperative complications

,

perivascular epithelioid cell neoplasms

,

mesenchymal chondrosarcoma

,

,

plasma cell granuloma

,

choroid plexus neoplasms

,

retinal neoplasms

,

,

extravasation of diagnostic and therapeutic materials

,

progression-free survival

,

beckwith-wiedemann syndrome

,

adrenal cortex neoplasms

,

unknown primary neoplasms

,

respiratory insufficiency

,

connective tissue neoplasms

,

diastolic heart failure

,

,

positron-emission tomography

,

adolescent development

,

breast neoplasms

,

,

,

myeloid leukemia acute

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

non-hodgkin lymphoma

,

large b-cell lymphoma diffuse

,

myeloid leukemia

,

,

b-cell lymphoma

,

triple negative breast neoplasms

,

lymphoid leukemia

,

,

hodgkin disease

,

liver neoplasms

,

myelodysplastic syndromes

,

,

hepatocellular carcinoma

,

multiple myeloma

,

follicular lymphoma

,

burkitt lymphoma

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

plasma cell neoplasms

,

,

,

urinary bladder neoplasms

,

mantle-cell lymphoma

,

biphenotypic leukemia acute

,

,

large-cell lymphoma anaplastic

,

rhabdomyosarcoma

,

cardiomyopathies

,

promyelocytic leukemia acute

,

philadelphia chromosome

,

immunoblastic lymphadenopathy

,

,

enteropathy-associated t-cell lymphoma

,

brain stem neoplasms

,

lymphoproliferative disorders

,

takotsubo cardiomyopathy

,

non-muscle invasive bladder neoplasms

,

breast diseases

,

second primary neoplasms

,

,

,

systolic heart failure

,

mediastinal neoplasms

,

,

male infertility

,

,

circulating neoplastic cells

,

alopecia areata

,

,

peripheral nervous system diseases

,

myocardial infarction

,

,

wounds and injuries

,

carcinoid tumor

,

,

erectile dysfunction

,

diabetic neuropathies

,

,

biliary tract neoplasms

,

,

ataxia telangiectasia

,

,

cerebellar ataxia

,

cardiac rehabilitation

,

chromosome disorders

,

gonadal disorders

,

,

cerebrovascular disorders

,

retroperitoneal neoplasms

,

endomyocardial fibrosis

,

pseudomyxoma peritonei

,

therapeutic chemoembolization

,

liver transplantation

,

malignant carcinoid syndrome

,

,

hyperlipidemias

,

diabetes mellitus

,

metabolic syndrome

,

hyperlipoproteinemias

,

intraductal carcinoma noninfiltrating

,

,

echocardiography

,

environmental biomarkers

,

myocardial contraction

,

physiological sexual dysfunction

,

,

,

cognitive dysfunction

,

peripheral arterial disease

,

peripheral vascular diseases

,

radiation injuries

,

eye abnormalities

,

,

gastrointestinal microbiome

,

coronary artery disease

,

microvascular angina

,

,

,

aortic valve stenosis

,

serotonin syndrome

,

,

cardiac imaging techniques

,

,

early detection of cancer

wasting syndrome

,

healthy volunteers/patients

Fluoroquinolone

,

type 2 diabetes mellitus

,

long qt syndrome

,

,

alzheimer disease

,

,

,

,

,

,

,

photosensitivity disorders

,

chronic renal insufficiency

,

kidney diseases

,

migraine disorders

,

,

pulmonary arterial hypertension

,

,

coronary artery disease

,

cardiovascular abnormalities

,

erectile dysfunction

,

major depressive disorder

,

electrocardiography

,

,

,

,

rheumatoid arthritis

,

,

,

therapeutic equivalency

,

psychotic disorders

,

,

thrombocytopenic purpura idiopathic

,

,

renal cell carcinoma

,

human influenza

,

polycythemia vera

,

duchenne muscular dystrophy

,

autoimmune diseases

,

orthostatic hypotension

,

acute coronary syndrome

,

lecithin cholesterol acyltransferase deficiency

,

,

lice infestations

,

restless legs syndrome

,

marijuana abuse

,

falciparum malaria

,

allergic rhinitis

,

,

retinal diseases

,

,

,

alcoholic liver cirrhosis

,

alcoholic hepatitis

,

hepatolenticular degeneration

,

,

acinetobacter infections

,

systemic lupus erythematosus

,

,

renal insufficiency

,

,

premature obstetric labor

,

premature birth

,

,

,

respiration disorders

,

,

,

,

,

human experimentation

,

myocardial ischemia

,

phase i metabolic detoxication

,

periapical periodontitis

,

,

phototoxic dermatitis

,

,

,

,

,

short bowel syndrome

,

non-alcoholic fatty liver disease

,

alcoholic fatty liver

,

smoking cessation

,

multiple endocrine neoplasia type 1

,

postpartum hemorrhage

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

respiratory syncytial virus infections

,

bacterial vaginosis

,

retinal vein occlusion

,

,

choroidal neovascularization

,

pathologic neovascularization

,

sickle cell anemia

,

,

,

pharmacokinetics

,

,

escherichia coli infections

,

,

infectious arthritis

,

,

,

,

otorhinolaryngologic diseases

,

parkinson disease

,

methicillin-resistant staphylococcus aureus

,

,

pharmacological phenomena

,

pulmonary sarcoidosis

,

,

refractive errors

,

,

pancreatic ductal carcinoma

,

systemic inflammatory response syndrome

,

,

,

,

amyotrophic lateral sclerosis

,

anastomotic leak

,

cutaneous leishmaniasis

,

mycobacterium avium-intracellulare infection

,

staphylococcal skin infections

,

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

neoplasm metastasis

,

,

anorexia nervosa

,

,

,

graft vs host disease

,

muscle spasticity

,

interstitial lung diseases

,

myeloid leukemia

,

lymphoid leukemia

,

hepatopulmonary syndrome

,

corneal injuries

,

,

rectal neoplasms

,

,

,

castration-resistant prostatic neoplasms

,

periapical diseases

,

colorectal neoplasms

,

,

,

,

,

acquired immunodeficiency syndrome

,

,

,

,

,

community-acquired infections

,

extensively drug-resistant tuberculosis

,

multiple myeloma

,

mycobacterium infections

,

,

infectious skin diseases

,

bacterial skin diseases

,

,

respiratory tract diseases

,

plasma cell neoplasms

,

latent tuberculosis

,

,

myelodysplastic syndromes

,

prosthesis-related infections

,

wounds and injuries

,

,

large b-cell lymphoma diffuse

,

,

b-cell chronic lymphocytic leukemia

,

hodgkin disease

,

,

,

,

,

congenital abnormalities

,

healthcare-associated pneumonia

,

aids-related opportunistic infections

,

urologic diseases

,

bronchial diseases

,

sezary syndrome

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mantle-cell lymphoma

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

burkitt lymphoma

,

large-cell lymphoma immunoblastic

,

,

clostridium infections

,

meningeal tuberculosis

,

enterobacteriaceae infections

,

neurogenic urinary bladder

,

,

ventilator-associated pneumonia

,

biphenotypic leukemia acute

,

,

,

,

wound infection

,

abdominal abscess

,

pelvic infection

,

ovarian neoplasms

,

myeloproliferative disorders

,

myelomonocytic leukemia chronic

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia chronic-phase

,

myeloid leukemia accelerated phase

,

hairy cell leukemia

,

testicular neoplasms

,

,

paranasal sinus diseases

,

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

intraocular lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

central nervous system neoplasms

,

,

,

phenylketonurias

,

mycobacterium tuberculosis

,

,

hematologic neoplasms

,

,

,

musculoskeletal pain

,

systolic heart failure

,

sick sinus syndrome

,

,

,

gram-positive bacterial infections

,

triple negative breast neoplasms

,

,

primary myelofibrosis

,

,

leukemia myeloid chronic atypical bcr-abl negative

,

gestational trophoblastic disease

,

ovarian epithelial carcinoma

,

neutrophilic leukemia chronic

,

trophoblastic neoplasms

,

nervous system diseases

,

hereditary congenital and neonatal diseases and abnormalities

,

neural tube defects

,

nervous system malformations

,

spinal dysraphism

,

ocular hypertension

,

open-angle glaucoma

,

,

,

sphenoid sinusitis

,

,

hematopoietic stem cell transplantation

,

prolymphocytic leukemia

,

large granular lymphocytic leukemia

,

,

small cell lung carcinoma

,

phacoemulsification

,

nontuberculous mycobacterium infections

,

acute cholecystitis

,

,

esophageal and gastric varices

,

intestinal neoplasms

,

nervous system neoplasms

,

salivary gland diseases

,

neurologic manifestations

,

,

acquired joint deformities

,

,

hematologic diseases

,

acanthamoeba keratitis

,

agammaglobulinemia

,

hidradenitis suppurativa

,

,

lymph node tuberculosis

,

prostatic diseases

,

healthy volunteers/patients

,

,

urinary tract infections

,

communicable diseases

,

,

,

pulmonary tuberculosis

,

chronic obstructive pulmonary disease

,

bacterial infections

,

multidrug-resistant tuberculosis

,

helicobacter infections

,

community-acquired pneumonia

,

,

,

,

,

chronic bronchitis

,

,

bacterial conjunctivitis

,

respiratory tract infections

,

,

,

,

,

liver cirrhosis

,

,

,

bacterial pneumonia

,

,

cystic fibrosis

,

endophthalmitis

,

,

,

prostatic neoplasms

,

,

diabetes mellitus

,

myeloid leukemia acute

,

,

breast neoplasms

,

,

,

disease susceptibility

,

disease progression

,

non-hodgkin lymphoma

,

cataract extraction

,

,

pseudomonas infections

,

febrile neutropenia

,

,

,

,

,

,

cardiovascular diseases

,

precursor cell lymphoblastic leukemia-lymphoma

,

intraabdominal infections

,

respiratory aspiration

,

,

,

,

,

critical illness

,

urinary bladder neoplasms

,

,

corneal diseases

,

,

,

,

,

maxillary sinusitis

,

nephrolithiasis

,

,

insulin resistance

,

,

drug-related side effects and adverse reactions

,

prostatic hyperplasia

,

microbial drug resistance

,

surgical wound infection

,

retinal detachment

,

obstructive lung diseases

,

overactive urinary bladder

,

,

,

inflammatory bowel diseases

,

dental pulp necrosis

,

postoperative pain

,

,

cardiac arrhythmias

,

cross infection

,

,

pelvic inflammatory disease

,

,

,

antibiotic prophylaxis

,

,

bacillary dysentery

,

,

mycoplasma pneumonia

,

pyogenic liver abscess

,

osteoarticular tuberculosis

,

,

ulcerative colitis

,

otitis media with effusion

,

pancreatic neoplasms

,

macular degeneration

,

pseudomonas aeruginosa

,

intravenous substance abuse

,

hypersensitivity

,

aspiration pneumonia

,

chronic periodontitis

,

corneal transplantation

,

bacterial eye infections

,

aggressive periodontitis

,

soft tissue infections

,

meningococcal meningitis

,

pancreatic cyst

,

gastroenteritis

,

postoperative complications

,

chlamydia infections

,

adaptive immunity

,

klebsiella infections

,

,

pneumococcal pneumonia

,

periapical abscess

,

patient preference

,

suppurative otitis media

,

,

,

,

contraception behavior

,

heart disease risk factors

,

glucose intolerance

,

,

,

intravitreal injections

,

patient compliance

,

metabolic syndrome

,

,

intravesical administration

,

non-muscle invasive bladder neoplasms

,

mycoplasma pneumoniae

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

kidney transplantation

,

polyomavirus infections

,

,

,

,

,

penetrating eye injuries

,

,

ophthalmologic surgical procedures

,

hepatorenal syndrome

,

,

hereditary angioedemas

,

ureteral calculi

,

,

herpesviridae infections

,

substance-related disorders

,

bacterial endocarditis

,

,

,

pulmonary infarction

,

haemophilus infections

,

,

urinary diversion

,

staphylococcal infections

,

,

ischemic stroke

,

bacterial drug resistance

,

staphylococcus aureus

,

,

,

pathologic dilatation

,

drug monitoring

,

deglutition disorders

,

clostridioides difficile

,

,

aortic dissection

,

,

mycoplasma infections

,

pleuropneumonia

,

,

inappropriate prescribing

,

chemical and drug induced liver injury

,

,

venous thrombosis

,

drug resistance

,

,

,

,

,

,

hyperaldosteronism

,

,

sleep initiation and maintenance disorders

,

,

,

,

general anesthesia

,

,

,

,

gram-negative bacterial infections

,

,

bacterial meningitis

,

central nervous system infections

,

neuromuscular blockade

,

,

,

cytomegalovirus retinitis

,

,

adenoviridae infections

,

port-wine stain

,

,

,

capillary hemangioma

,

bipolar disorder

,

autistic disorder

,

,

,

treatment-resistant schizophrenia

,

potassium deficiency

,

asymptomatic infections

,

,

,

extracorporeal circulation

,

,

,

precancerous conditions

,

,

,

stenotrophomonas maltophilia

,

percutaneous nephrolithotomy

,

,

dissociative disorders

,

,

reactive arthritis

,

chronic kidney failure

,

musculoskeletal diseases

,

catheter-related infections

,

portal hypertension

,

myocardial revascularization

,

emergency treatment

,

,

,

multiple drug resistance

,

physical exertion

,

laboratory infection

,

,

uterine hemorrhage

,

spontaneous abortion

,

blood transfusion

,

lymphatic diseases

,

traumatic brain injuries

,

pleural empyema

,

root resorption

,

persistent infection

,

torsades de pointes

healthy volunteers/patients

,

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

chronic progressive multiple sclerosis

,

,

,

equipment and supplies

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