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ADC Therapeutics
ADC Therapeutics
(ADCT)
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Therapeutic Areas:
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Zynlonta
Loncastuximab tesirine
2021-04-23
Large b-cell lymphoma diffuse
,
B-cell lymphoma
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Loncastuximab tesirine
burkitt lymphoma
,
leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
central nervous system neoplasms
,
follicular lymphoma
,
mantle-cell lymphoma
,
b-cell chronic lymphocytic leukemia
,
b-cell lymphoma marginal zone
,
waldenstrom macroglobulinemia
,
recurrence
,
b-cell lymphoma
,
lymphoma
,
large b-cell lymphoma diffuse
,
non-hodgkin lymphoma
,
hodgkin disease
,
sepsis
,
agranulocytosis
,
opportunistic infections
Epratuzumab
leukemia
,
recurrence
,
precursor cell lymphoblastic leukemia-lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
follicular lymphoma
,
large b-cell lymphoma diffuse
,
aggression
,
waldenstrom macroglobulinemia
,
b-cell lymphoma
,
lymphoma
,
non-hodgkin lymphoma
Edrecolomab
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
large b-cell lymphoma diffuse
,
multiple myeloma
,
non-hodgkin lymphoma
,
lymphoma
,
b-cell lymphoma
,
b-cell chronic lymphocytic leukemia
,
residual neoplasm
,
lung neoplasms
,
small cell lung carcinoma
,
neuroendocrine carcinoma
,
breast neoplasms
Calcium dobesilate
castration-resistant prostatic neoplasms
,
non-hodgkin lymphoma
,
colorectal neoplasms
,
multiple myeloma
,
recurrence
,
plasma cell neoplasms
,
prostatic neoplasms
,
neoplasms
,
vomiting
,
nausea
,
drug-related side effects and adverse reactions
,
sarcoma
Lornoxicam
non-hodgkin lymphoma
,
b-cell lymphoma marginal zone
,
follicular lymphoma
Bevifimod
hematologic neoplasms
,
biphenotypic leukemia acute
,
b-cell leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
stomach neoplasms
,
stroke
,
muscle spasticity
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
precursor b-cell lymphoblastic leukemia-lymphoma
,
endometriosis
,
infertility
,
b-cell lymphoma
,
recurrence
,
ovarian neoplasms
,
b-cell lymphoma marginal zone
,
fallopian tube neoplasms
,
multiple myeloma
,
prostatic neoplasms
,
pancreatic neoplasms
,
burkitt lymphoma
,
triple negative breast neoplasms
,
esophageal neoplasms
,
squamous cell carcinoma of head and neck
,
reactive arthritis
,
waldenstrom macroglobulinemia
,
lymphoproliferative disorders
,
lymphatic diseases
,
intestinal neoplasms
,
colonic neoplasms
,
rectal neoplasms
,
carcinoma
,
glioblastoma
,
melanoma
,
neuroendocrine carcinoma
,
papillary thyroid cancer
,
adenocarcinoma
,
primary myelofibrosis
,
hairy cell leukemia
,
abdominal hernia
,
ventral hernia
,
myelodysplastic syndromes
,
breast neoplasms
,
urinary bladder neoplasms
,
uterine neoplasms
,
myeloid leukemia
,
knee osteoarthritis
,
residual neoplasm
,
neuralgia
,
interstitial cystitis
,
neoadjuvant therapy
,
ovarian epithelial carcinoma
,
mantle-cell lymphoma
,
female genital neoplasms
,
peritoneal neoplasms
,
neoplasms
,
non-hodgkin lymphoma
,
crohn disease
,
non-small-cell lung carcinoma
,
b-cell chronic lymphocytic leukemia
,
lymphoma
,
myeloid leukemia acute
,
colorectal neoplasms
,
large b-cell lymphoma diffuse
,
follicular lymphoma
,
lung neoplasms
,
joint diseases
,
musculoskeletal diseases
,
ankylosing spondylitis
,
small cell lung carcinoma
,
neoplasm metastasis
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
inflammatory bowel diseases
,
macular degeneration
,
leukemia
,
lymphoid leukemia
,
spondylitis
,
juvenile arthritis
,
skin diseases
,
papulosquamous skin diseases
,
wet macular degeneration
,
infections
,
communicable diseases
,
bacterial infections
,
methicillin-resistant staphylococcus aureus
,
staphylococcal skin infections
,
infectious skin diseases
,
bacterial skin diseases
,
cellulitis
,
disease progression
,
covid-19
,
parkinson disease
,
bronchopulmonary dysplasia
,
respiratory syncytial viruses
,
hepatitis b
,
ulcer
,
pyoderma gangrenosum
,
spondylarthropathies
,
spondylarthritis
,
spinal diseases
,
uveitis
,
intermediate uveitis
,
posterior uveitis
,
precocious puberty
,
migraine disorders
,
retinal diseases
,
retinal degeneration
,
eye diseases
,
choroidal neovascularization
,
hepatocellular carcinoma
,
liver neoplasms
,
thyroid diseases
,
hypothyroidism
,
rheumatoid arthritis
,
psoriasis
,
arthritis
,
ulcerative colitis
,
psoriatic arthritis
,
hepatitis c
,
chronic hepatitis c
,
hidradenitis suppurativa
,
axial spondyloarthritis
,
cardiovascular diseases
,
connective tissue diseases
,
seizures
,
panuveitis
,
hiv infections
,
drug monitoring
,
coronary artery disease
,
myocardial ischemia
,
inflammation
,
atherosclerosis
CAMIDANLUMAB
renal cell carcinoma
,
carcinoma
,
colorectal neoplasms
,
ovarian neoplasms
,
pancreatic neoplasms
,
non-small-cell lung carcinoma
,
triple negative breast neoplasms
,
stomach neoplasms
,
esophageal neoplasms
,
urinary bladder neoplasms
,
fallopian tube neoplasms
,
squamous cell carcinoma of head and neck
,
melanoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
non-hodgkin lymphoma
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
hodgkin disease
,
myelodysplastic syndromes
,
neoplasms
,
myeloproliferative disorders
,
myelodysplastic-myeloproliferative diseases
,
preleukemia
,
lymphoma
CAMIDANLUMAB TESIRINE
non-small-cell lung carcinoma
,
urinary bladder neoplasms
,
renal cell carcinoma
,
carcinoma
,
colorectal neoplasms
,
ovarian neoplasms
,
pancreatic neoplasms
,
triple negative breast neoplasms
,
stomach neoplasms
,
esophageal neoplasms
,
fallopian tube neoplasms
,
squamous cell carcinoma of head and neck
,
melanoma
,
breast neoplasms
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
non-hodgkin lymphoma
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
hodgkin disease
,
myelodysplastic syndromes
,
neoplasms
,
myeloproliferative disorders
,
myelodysplastic-myeloproliferative diseases
,
preleukemia
,
lymphoma
Doxecitine
melanoma
,
central nervous system neoplasms
,
stomach neoplasms
,
brain neoplasms
,
medulloblastoma
,
camurati-engelmann syndrome
,
thyroid neoplasms
,
glioblastoma
,
glioma
,
chondrosarcoma
,
endometrial neoplasms
,
renal cell carcinoma
,
sarcoma
,
non-hodgkin lymphoma
,
biliary tract neoplasms
,
lymphoma
,
prostatic neoplasms
,
ovarian epithelial carcinoma
,
pancreatic ductal carcinoma
,
recurrence
,
large b-cell lymphoma diffuse
,
urologic neoplasms
,
esophageal neoplasms
,
non-muscle invasive bladder neoplasms
,
carcinoma
,
inflammatory breast neoplasms
,
extranodal nk-t-cell lymphoma
,
sezary syndrome
,
mycosis fungoides
,
t-cell lymphoma cutaneous
,
head and neck neoplasms
,
hodgkin disease
,
large-cell lymphoma immunoblastic
,
synovial sarcoma
,
respiratory tract diseases
,
lung diseases
,
respiratory tract neoplasms
,
thoracic neoplasms
,
mesothelioma
,
squamous cell neoplasms
,
adolescent development
,
small cell carcinoma
,
b-cell lymphoma marginal zone
,
large-cell lymphoma anaplastic
,
precursor cell lymphoblastic leukemia-lymphoma
,
follicular lymphoma
,
hepatocellular carcinoma
,
liver neoplasms
,
malignant pleural effusion
,
mantle-cell lymphoma
,
b-cell lymphoma
,
kidney neoplasms
,
non-small-cell lung carcinoma
,
neoplasms
,
pancreatic neoplasms
,
lung neoplasms
,
neoplasm metastasis
,
ovarian neoplasms
,
colorectal neoplasms
,
urinary bladder neoplasms
,
peritoneal neoplasms
,
fallopian tube neoplasms
,
cholangiocarcinoma
,
colonic neoplasms
,
adenocarcinoma
,
rectal neoplasms
,
transitional cell carcinoma
,
gallbladder neoplasms
,
female genital neoplasms
,
pelvic neoplasms
,
uterine cervical neoplasms
,
gastrointestinal neoplasms
,
unknown primary neoplasms
,
digestive system neoplasms
,
rectal diseases
,
gastrointestinal diseases
,
intestinal neoplasms
,
digestive system diseases
,
colonic diseases
,
intestinal diseases
,
breast neoplasms
Loncastuximab
burkitt lymphoma
,
leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
central nervous system neoplasms
,
follicular lymphoma
,
mantle-cell lymphoma
,
b-cell chronic lymphocytic leukemia
,
b-cell lymphoma marginal zone
,
waldenstrom macroglobulinemia
,
recurrence
,
b-cell lymphoma
,
lymphoma
,
large b-cell lymphoma diffuse
,
non-hodgkin lymphoma
,
hodgkin disease
,
sepsis
,
agranulocytosis
,
opportunistic infections
Nepidermin
healthy volunteers/patients
,
melanoma
,
pheochromocytoma
,
neuroendocrine tumors
,
paraganglioma
,
meningeal carcinomatosis
,
meningitis
,
laryngeal neoplasms
,
pancreatic ductal carcinoma
,
obesity
,
head and neck neoplasms
,
squamous cell neoplasms
,
transitional cell carcinoma
,
malignant pleural effusion
,
fallopian tube neoplasms
,
small cell carcinoma
,
gastrointestinal neoplasms
,
dna repair-deficiency disorders
,
urinary bladder neoplasms
,
salivary gland neoplasms
,
xerostomia
,
mucositis
,
radiation injuries
,
radiation effects
,
germ cell and embryonal neoplasms
,
peritoneal neoplasms
,
skin neoplasms
,
pleural effusion
,
lung injury
,
residual neoplasm
,
breast neoplasms
,
type 2 diabetes mellitus
,
diabetes mellitus
,
carcinoma
,
neoplasms
,
neoplasm metastasis
,
prostatic neoplasms
,
asthma
,
adenocarcinoma
,
small cell lung carcinoma
,
gastroesophageal reflux
,
duodenal ulcer
,
ulcer
,
esophagitis
,
heart failure
,
rheumatoid arthritis
,
castration-resistant prostatic neoplasms
,
triple negative breast neoplasms
,
ovarian neoplasms
,
neoplasms by site
,
depression
,
major depressive disorder
,
depressive disorder
,
covid-19
,
peptic esophagitis
,
stomach ulcer
,
colorectal neoplasms
,
arthritis
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
renal cell carcinoma
,
endometrial neoplasms
,
recurrence
,
hypertension
,
urologic neoplasms
,
stomach neoplasms
,
lung diseases
,
hepatocellular carcinoma
,
liver neoplasms
,
peptic ulcer
,
kidney diseases
,
hyperglycemia
,
cardiovascular diseases
,
pancreatic neoplasms
,
ovarian epithelial carcinoma
,
breast diseases
,
sickle cell anemia
,
brain neoplasms
,
heartburn
,
constipation
,
opioid-induced constipation
,
glioblastoma
,
hypercholesterolemia
,
biliary tract neoplasms
,
gallbladder neoplasms
,
hereditary breast and ovarian cancer syndrome
,
brca2 genes
,
chronic renal insufficiency
,
albuminuria
,
body weight
,
glucose metabolism disorders
,
metabolic diseases
,
endocrine system diseases
,
hypersensitivity
,
skin diseases
,
kidney neoplasms
,
gastrinoma
,
zollinger-ellison syndrome
,
hemorrhage
,
peptic ulcer hemorrhage
,
osteoarthritis
,
low back pain
,
chronic obstructive pulmonary disease
,
obstructive lung diseases
,
crohn disease
,
anxiety disorders
,
gynecomastia
,
venous thrombosis
,
pulmonary embolism
,
plexiform neurofibroma
,
neurofibromatosis 1
,
unknown primary neoplasms
,
respiratory insufficiency
,
myocardial infarction
,
coronary artery disease
,
bile duct neoplasms
,
cholangiocarcinoma
,
klatskin tumor
,
respiratory syncytial virus infections
,
uterine neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
respiratory tract diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
thoracic neoplasms
,
bronchial neoplasms
Odronextamab
b-cell chronic lymphocytic leukemia
,
reactive arthritis
,
lupus nephritis
,
systemic lupus erythematosus
,
mantle-cell lymphoma
,
follicular lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
lymphoma
,
non-hodgkin lymphoma
,
b-cell lymphoma marginal zone
,
recurrence
,
hodgkin disease
Palifosfamide
non-hodgkin lymphoma
,
lymphoma
,
hodgkin disease
,
b-cell lymphoma
Globulin, immune
hematologic neoplasms
,
carcinoma
,
neoplasm metastasis
,
b-cell leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
biphenotypic leukemia acute
,
hiv infections
,
hiv-1
,
acquired immunodeficiency syndrome
,
hiv-2
,
immunologic deficiency syndromes
,
sarcoma
,
squamous cell carcinoma
,
malignant fibrous histiocytoma
,
pancreatic neoplasms
,
stomach neoplasms
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
precursor b-cell lymphoblastic leukemia-lymphoma
,
t-cell lymphoma
,
endometrial neoplasms
,
uterine cervical neoplasms
,
myelodysplastic syndromes
,
myelodysplastic-myeloproliferative diseases
,
b-cell lymphoma
,
non-small-cell lung carcinoma
,
recurrence
,
b-cell lymphoma marginal zone
,
plasma cell neoplasms
,
small cell lung carcinoma
,
squamous cell carcinoma of head and neck
,
mantle-cell lymphoma
,
lymphoproliferative disorders
,
adenocarcinoma
,
burkitt lymphoma
,
lung neoplasms
,
breast neoplasms
,
triple negative breast neoplasms
,
esophageal neoplasms
,
immunoglobulin light-chain amyloidosis
,
amyloidosis
,
reactive arthritis
,
waldenstrom macroglobulinemia
,
residual neoplasm
,
myeloid leukemia
,
myeloproliferative disorders
,
lymphatic diseases
,
intestinal neoplasms
,
colonic neoplasms
,
rectal neoplasms
,
asthma
,
hairy cell leukemia
,
smoldering multiple myeloma
,
prostatic neoplasms
,
urinary bladder neoplasms
,
uterine neoplasms
,
amyloid plaque
,
knee osteoarthritis
,
blastic plasmacytoid dendritic cell neoplasm
,
neoadjuvant therapy
,
female genital neoplasms
,
neoplasms
,
non-hodgkin lymphoma
,
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell chronic lymphocytic leukemia
,
colorectal neoplasms
,
follicular lymphoma
,
fallopian tube neoplasms
,
myeloid leukemia acute
,
ovarian neoplasms
,
multiple myeloma
,
joint diseases
,
musculoskeletal diseases
,
leukemia
,
peritoneal neoplasms
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
brain neoplasms
,
glioblastoma
,
juvenile arthritis
,
skin diseases
,
papulosquamous skin diseases
,
ulcer
,
macular degeneration
,
lymphoid leukemia
,
ovarian epithelial carcinoma
,
covid-19
,
gliosarcoma
,
bronchopulmonary dysplasia
,
respiratory syncytial viruses
,
pyoderma gangrenosum
,
spondylarthropathies
,
spinal diseases
,
uveitis
,
intermediate uveitis
,
posterior uveitis
,
retinal diseases
,
wet macular degeneration
,
retinal degeneration
,
eye diseases
,
choroidal neovascularization
,
hepatocellular carcinoma
,
liver neoplasms
,
pouchitis
,
rheumatoid arthritis
,
psoriasis
,
crohn disease
,
arthritis
,
ulcerative colitis
,
psoriatic arthritis
,
ankylosing spondylitis
,
inflammatory bowel diseases
,
spondylitis
,
hidradenitis suppurativa
,
axial spondyloarthritis
,
spondylarthritis
,
cardiovascular diseases
,
connective tissue diseases
,
panuveitis
,
pathologic constriction
,
intestinal diseases
,
colitis
,
atopic dermatitis
,
atherosclerosis
,
drug monitoring
Anthracycline
neoplasms
,
hiv infections
,
kaposi sarcoma
,
sarcoma
,
non-hodgkin lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
triple negative breast neoplasms
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
aggression
,
esophageal neoplasms
,
neoplasm metastasis
,
leukemia
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
myeloid leukemia
,
preleukemia
,
syndrome
,
breast neoplasms
,
hodgkin disease
,
lymphoma
1
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