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Drug ReportsSalicylic acid
Salicylic acid
Salicylic acid is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target acid-sensing ion channel 3.
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Clinical
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Target
Variants
Financial
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Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name
Status
Last Update
111medco 2% salicylic acid cleansing barC2002632023-12-12
24 alopecia reliefshampoounapproved drug other2020-08-08
28.5% salicylic acidunapproved drug other2018-04-06
3 in 1 cleanserOTC monograph final2020-09-16
3-1 acne treatment padsC2002632024-10-09
30 day acne treatment kitOTC monograph final2023-08-23
45% urea cream 2% salicylic acidC2002632024-10-17
aavrani dry scalp rescue serumC2002632023-10-25
ac out spot stop serumunapproved drug other2012-09-25
acence tea tree tock blemish spotOTC monograph final2016-01-22
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
D: Dermatologicals
D01: Antifungals for dermatological use
D01A: Antifungals for topical use
D01AE: Other antifungals for topical use in atc
D01AE12: Salicylic acid
D02: Emollients and protectives
D02A: Emollients and protectives
D02AF: Salicylic acid emollient and protective preparations
M: Musculo-skeletal system drugs
M02: Topical products for joint and muscular pain
M02A: Topical products for joint and muscular pain
M02AC: Preparations with salicylic acid derivatives, topical for joint and muscle pain
N: Nervous system drugs
N02: Analgesics
N02B: Other analgesics and antipyretics in atc
N02BA: Salicylic acid and derivatives, analgesics and antipyretics
P: Antiparasitic products, insecticides and repellents
P02: Anthelmintics
P02D: Anticestodals
P02DA: Salicylic acid derivative anticestodals
S: Sensory organ drugs
S01: Ophthalmologicals
S01B: Antiinflammatory agents, ophthalmologic
S01BC: Antiinflammatory agents, non-steroidal, ophthalmologic
S01BC08: Salicylic acid
HCPCS
No data
Clinical
Clinical Trials
3632 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
StrokeD020521EFO_0000712I63.9734356225298
Ischemic strokeD000083242825294182239
IschemiaD007511EFO_00005561721164171221
Retinal vein occlusionD012170EFO_1001157H34.813347513174214
Coronary artery diseaseD003324I25.1191212176207
Arterial occlusive diseasesD001157EFO_000908515181917120182
Peripheral arterial diseaseD058729EFO_000426511191214124172
Macular edemaD0082691927362647142
Peripheral vascular diseasesD016491EFO_0003875I73.9513101089121
Atrial fibrillationD001281EFO_0000275I48.01359102118
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Indications Phases 2
Indications Phases 1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Respiratory aspirationD053120EFO_10018391313
Anterior cruciate ligament injuriesD0000705981313
Blood flow restriction therapyD0000900031313
Bone fracturesD050723EFO_0003931T14.81212
Muscle weaknessD018908HP_00013241111
Patent foramen ovaleD054092HP_0001655Q21.121111
Intracranial arteriosclerosisD002537EFO_1000860I67.21010
EmergenciesD0046301010
Edentulous jawD0075751010
Subarachnoid hemorrhageD013345EFO_0000713I6099
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameSalicylic acid
INN
Description
Salicylic acid is a monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves. It has a role as an antiinfective agent, an antifungal agent, a keratolytic drug, an EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor, a plant metabolite, an algal metabolite and a plant hormone. It is a conjugate acid of a salicylate.
Classification
Small molecule
Drug classanti-inflammatory agents (salicylic acid derivatives)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
O=C(O)c1ccccc1O
Identifiers
PDB
CAS-ID69-72-7
RxCUI
ChEMBL IDCHEMBL424
ChEBI ID16914
PubChem CID338
DrugBankDB00936
UNII ID
Target
No data
Variants
No data
Financial
Revenue by drug
$
£
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Estimated US medical usage
Salicylic acid
Total medical expenditures per year (USD, in millions)
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Salicylic acid
+
Sulfur
Total medical expenditures per year (USD, in millions)
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Trends
PubMed Central
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Additional graphs summarizing 234,599 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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34,329 adverse events reported
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