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Drug ReportsPenicillin g
Benzylpenicillin
Benzylpenicillin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
Penicillin g (discontinued: Penicillin g)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name
Status
Last Update
bicillin c-r 900/300New Drug Application2024-06-03
bicillin crNew Drug Application2024-06-04
bicillin l-aNew Drug Application2024-07-12
buffered penicillin g potassiumANDA2020-02-22
extencillineunapproved drug for use in drug shortage2024-07-18
lentocilinunapproved drug for use in drug shortage2024-06-07
penicillin g potassiumANDA2024-06-28
penicillin g sodiumANDA2020-05-27
pfizerpenANDA2024-08-27
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
respiratory tract infections—D012141J06.9
pericarditisEFO_0007427D010493I30
urinary tract infectionsEFO_0003103D014552N39.0
pneumococcal infectionsEFO_0000772D011008J13
bacterial infections—D001424A49
gonorrheaDOID_7551D006069A54
bacterial skin diseases—D017192—
escherichia coli infectionsEFO_1001318D004927B96.20
syphilisEFO_0007504D013587A53.9
staphylococcal infections—D013203A49.01
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01C: Beta-lactam antibacterials, penicillins
— J01CE: Beta-lactamase sensitive penicillins
— J01CE01: Benzylpenicillin
— J01CE08: Benzathine benzylpenicillin
— J01CE09: Procaine benzylpenicillin
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AA: Antibiotics, ophthalmologic
— S01AA14: Benzylpenicillin
HCPCS
No data
Clinical
Clinical Trials
97 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SyphilisD013587EFO_0007504A53.91356317
InfectionsD007239EFO_0000544——256214
Communicable diseasesD003141————2428
PneumoniaD011014EFO_0003106——14127
SepsisD018805HP_0100806A41.9——2125
Hiv infectionsD015658EFO_0000764B20—12114
HypersensitivityD006967HP_0012393T78.40—1—124
YawsD015001EFO_0007548A66——21—3
Respiratory tract infectionsD012141—J06.9———123
BacteremiaD016470EFO_0003033R78.81—1—2—3
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bacterial infectionsD001424—A49——1—23
NeurosyphilisD009494EFO_0007339A50.4——1—23
Treponemal infectionsD014211EFO_1001217———2——2
Neonatal sepsisD000071074HP_0040187———1—12
ToxemiaD014115————1—12
TuberculosisD014376EFO_0000774A15-A19—11——1
Cytomegalovirus infectionsD003586EFO_0001062B25—11——1
MalnutritionD044342EFO_0008572E40-E46——1——1
Microbial drug resistanceD004352————1——1
Severe acute malnutritionD000067011————1——1
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Heart diseasesD006331EFO_0003777I51.9—2——24
Rheumatic heart diseaseD012214EFO_1001161I09.9—2——24
Rheumatic diseasesD012216—M79.0—2——13
Urinary bladder neoplasmsD001749—C6721———3
Non-muscle invasive bladder neoplasmsD000093284——21———3
PsoriasisD011565EFO_0000676L40—1——12
Covid-19D000086382———1———1
DyspepsiaD004415EFO_0008533K30—1———1
Congenital abnormalitiesD000013EFO_0003915Q89.9—1———1
LymphangiomaD008202—D18.1—1———1
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———2————2
Streptococcal infectionsD013290EFO_1001476—1———12
PharyngitisD010612—R07.01———12
OsteomyelitisD010019EFO_0003102M861————1
AtrophyD001284——1————1
Bone regenerationD001861——1————1
Bacterial vaginosisD016585EFO_0003932—1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Impacted toothD014095HP_0011079K01.1————22
Drug monitoringD016903——————11
PharmacokineticsD010599——————11
Critical illnessD016638——————11
Hiv seropositivityD006679——————11
Breast neoplasmsD001943EFO_0003869C50————11
Urinary incontinenceD014549HP_0000020R32————11
Stress urinary incontinenceD014550HP_0010992—————11
EnuresisD004775—R32————11
Hepatitis cD006526—B19.2————11
Show 22 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBenzylpenicillin
INNbenzylpenicillin
Description
Benzylpenicillin is a penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group. It has a role as an antibacterial drug, an epitope and a drug allergen. It is a penicillin allergen and a penicillin. It is a conjugate acid of a benzylpenicillin(1-).
Classification
Small molecule
Drug classpenicillins
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O
Identifiers
PDB—
CAS-ID61-33-6
RxCUI—
ChEMBL IDCHEMBL29
ChEBI ID18208
PubChem CID5904
DrugBankDB01053
UNII IDQ42T66VG0C (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
Black-box warning for: Bicillin c-r 900/300, Bicillin cr, Bicillin l-a
Adverse Events
Top Adverse Reactions
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5,429 adverse events reported
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