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Drug ReportsCalcium dobesilate
Calcium dobesilate
Calcium dobesilate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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6M
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5Y
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
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Completion date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name
Status
Last Update
e l f camo semi matte cc spf 30 light 205 nC2002632024-02-06
Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C05: Vasoprotectives
— C05B: Antivaricose therapy drugs
— C05BX: Other sclerosing agents in atc
— C05BX01: Calcium dobesilate
— C05BX51: Calcium dobesilate, combinations
HCPCS
No data
Clinical
Clinical Trials
1375 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Multiple myelomaD009101—C90.01152096349338
Plasma cell neoplasmsD054219——1092006048320
LeukemiaD007938—C9536663026125
Precursor cell lymphoblastic leukemia-lymphomaD054198——33582825112
Macular edemaD008269——522213336112
Lymphoid leukemiaD007945—C913052232498
LymphomaD008223—C85.92755164294
EdemaD004487HP_0000969R60.952021212991
VomitingD014839HP_0002013R11.131434211584
NauseaD009325HP_0002018R11.021329201273
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AmyloidosisD000686EFO_1001875E8514183—230
Immunoglobulin light-chain amyloidosisD000075363——11133—225
Precursor t-cell lymphoblastic leukemia-lymphomaD054218——794——17
Mantle-cell lymphomaD020522——3141——16
Waldenstrom macroglobulinemiaD008258HP_0005508C88.04111——14
CarcinomaD002277—C80.0264—213
Myeloid leukemiaD007951—C92662——11
Smoldering multiple myelomaD000075122——291——11
Hodgkin diseaseD006689—C81452——11
Philadelphia chromosomeD010677——172——9
Show 111 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PlasmacytomaD010954—C90.346——211
Hematologic neoplasmsD019337——75———10
Follicular lymphomaD008224—C8226———7
T-cell leukemiaD015458——24———6
Blast crisisD001752——25———6
AdenocarcinomaD000230——33——16
Bcr-abl positive chronic myelogenous leukemiaD015464EFO_0000340—25———6
Plasma cell leukemiaD007952—C90.113——15
B-cell lymphoma marginal zoneD018442—C88.415———5
Ovarian neoplasmsD010051EFO_0003893C5621——24
Show 100 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———8———19
PruritusD011537HP_0000989L292———24
GlioblastomaD005909EFO_0000515—2———24
Cesarean sectionD002585——1———23
Castration-resistant prostatic neoplasmsD064129——3————3
Endometrioid carcinomaD018269——1———12
Ovarian epithelial carcinomaD000077216——1———12
Hairy cell leukemiaD007943—C91.42————2
Sickle cell anemiaD000755EFO_0000697D571———12
Sleep deprivationD012892—F51.122————2
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Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Deglutition disordersD003680HP_0002015R13.1————33
Respiratory soundsD012135HP_0010307R06.1————22
Ganglion cystsD045888—M67.4————22
NecrosisD009336——————22
MyopiaD009216EFO_0003927H52.1————22
AstigmatismD001251EFO_0004222H52.2————22
PregnancyD011247EFO_0002950Z33.1————22
Thyroid diseasesD013959HP_0000820E00-E07————22
HemorrhageD006470MP_0001914R58————22
Vascular diseasesD014652EFO_0004264I77————22
Show 77 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCalcium dobesilate
INNcalcium dobesilate
Description
Calcium dobesilate is a vasoprotective. It is the calcium salt of dobesilic acid. It is a synthetic molecule with the ability to reduce capillary permeability in the body. In Switzerland the drug is sold by the pharmaceutical company OM Pharma under the trade name of Doxium in capsules containing 500 mg of active ingredient.
Classification
Small molecule
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
O=S(=O)([O-])c1cc(O)ccc1O.O=S(=O)([O-])c1cc(O)ccc1O.[Ca+2]
Identifiers
PDB—
CAS-ID117552-78-0
RxCUI—
ChEMBL IDCHEMBL2106191
ChEBI ID—
PubChem CID29963
DrugBankDBSALT002519
UNII ID5921X1560Q (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 977 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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70 adverse events reported
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