Calcium dobesilate
Calcium dobesilate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| e l f camo semi matte cc spf 30 light 205 n | C200263 | 2024-11-06 |
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Clinical
Clinical Trials
1378 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Retinal vein occlusion | D012170 | EFO_1001157 | H34.81 | — | — | 1 | 1 | — | 2 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple myeloma | D009101 | — | C90.0 | 4 | 3 | 1 | — | — | 7 |
| Leukemia | D007938 | — | C95 | 1 | 3 | 1 | — | — | 4 |
| Macular edema | D008269 | — | — | — | — | 1 | — | — | 1 |
| Edema | D004487 | HP_0000969 | R60.9 | — | — | 1 | — | — | 1 |
| Vision disorders | D014786 | HP_0000505 | H53.11 | — | — | 1 | — | — | 1 |
| Low vision | D015354 | — | — | — | — | 1 | — | — | 1 |
| Myeloid leukemia acute | D015470 | — | C92.0 | — | — | 1 | — | — | 1 |
| Myeloid leukemia | D007951 | — | C92 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Plasma cell neoplasms | D054219 | — | — | 4 | 3 | — | — | — | 6 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | — | 1 | 3 | — | — | — | 3 |
| Lymphoid leukemia | D007945 | — | C91 | 1 | 3 | — | — | — | 3 |
| Lymphoma | D008223 | — | C85.9 | — | 2 | — | — | — | 2 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | — | 1 | — | — | — | 1 |
| Precursor t-cell lymphoblastic leukemia-lymphoma | D054218 | — | — | — | 1 | — | — | — | 1 |
| T-cell leukemia | D015458 | — | — | — | 1 | — | — | — | 1 |
| B-cell leukemia | D015448 | — | — | — | 1 | — | — | — | 1 |
| Arthritis | D001168 | HP_0001369 | M05-M14 | — | 1 | — | — | — | 1 |
| Gouty arthritis | D015210 | — | — | — | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | — | — | — | — | 1 |
| Malignant mesothelioma | D000086002 | — | — | 1 | — | — | — | — | 1 |
| Mesothelioma | D008654 | — | C45 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Calcium dobesilate |
| INN | calcium dobesilate |
| Description | Calcium dobesilate is a vasoprotective. It is the calcium salt of dobesilic acid.
It is a synthetic molecule with the ability to reduce capillary permeability in the body. In Switzerland the drug is sold by the pharmaceutical company OM Pharma under the trade name of Doxium in capsules containing 500 mg of active ingredient.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=S(=O)([O-])c1cc(O)ccc1O.O=S(=O)([O-])c1cc(O)ccc1O.[Ca+2] |
Identifiers
| PDB | — |
| CAS-ID | 117552-78-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2106191 |
| ChEBI ID | — |
| PubChem CID | 29963 |
| DrugBank | DBSALT002519 |
| UNII ID | 5921X1560Q (ChemIDplus, GSRS) |
Target
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
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70 adverse events reported
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