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Disease Reportsheart failure
MeSH D006333 - heart failure
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Competitive landscape
D006331:Heart diseases
0 Companies
0 Drugs
Success rate
D006333: 
Heart failure
D004418:Paroxysmal dyspnea
$
Success rate
D004489:Cardiac edema
0 Companies
0 Drugs
Success rate
D054143:Systolic heart failure
$
Success rate
D054144:Diastolic heart failure
0 Companies
0 Drugs
Success rate
D059347:Cardio-renal syndrome
0 Companies
0 Drugs
Success rate
Events Timeline
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Commercial
Company Name
Drug Name
Trade Name
Patent Expires
Approval Date
Revenue
Period
Salix PharmaceuticalsChlorothiazide Diuril  1982-01-01   
TevaValsartan, Amlodipine besylate Amlodipine Besylate Valsartan  2015-03-30   
Hydrochlorothiazide, Valsartan, Amlodipine besylate Amlodipine Besylate, Valsartan Hydrochlorothiazide  2012-09-25   
Valsartan Valsartan  2016-01-04   
Hydrochlorothiazide, Amiloride Amiloride Hydrochlorothiazide  1988-04-17   
Hydrochlorothiazide, Bisoprolol Bisoprolol Hydrochlorothiazide  2000-09-27   
Hydrochlorothiazide, Captopril Captopril Hydrochlorothiazide  1998-06-18   
Hydrochlorothiazide, Enalapril Enalapril Hydrochlorothiazide  2003-03-25   
Hydrochlorothiazide, Fosinopril Fosinopril Hydrochlorothiazide  2006-07-05   
Hydrochlorothiazide, Hydralazine, Reserpine Hydralazine Hydrochloride, Hydrochlorothiazide Reserpine  1982-01-01   
Hydrochlorothiazide, Hydralazine Hydralazine W/ Hydrochlorothiazide  1984-04-10   
Hydrochlorothiazide Hydrochlorothiazide  2005-07-13   
Hydrochlorothiazide, Reserpine Hydrochlorothiazide W/ Reserpine  1982-01-01   
Hydrochlorothiazide, Hydralazine, Reserpine Hydroserpine (r)  1982-01-01   
Irbesartan, Hydrochlorothiazide Irbesartan Hydrochlorothiazide  2012-03-30   
Irbesartan, Hydrochlorothiazide Irbesartan/Hydrochlorothiazide Teva  2009-11-26   
Hydrochlorothiazide, Lisinopril Lisinopril Hydrochlorothiazide  2002-07-01   
Hydrochlorothiazide, Losartan potassium Losartan Potassium Hydrochlorothiazide  2010-04-06   
Hydrochlorothiazide, Methyldopa Methyldopa Hydrochlorothiazide  1988-03-08   
Hydrochlorothiazide Microzide  1996-12-27   
Hydrochlorothiazide, Moexipril Moexipril Hydrochlorothiazide  2007-03-07   
Hydrochlorothiazide, Olmesartan medoxomil Olmesartan Medoxomil Hydrochlorothiazide  2017-04-24   
Hydrochlorothiazide, Olmesartan medoxomil, Amlodipine besylate Olmesartan Medoxomil, Amlodipine Hydrochlorothiazide  2016-11-03   
Propranolol, Hydrochlorothiazide Propranolol Hydrochlorothiazide  1988-12-01   
Hydrochlorothiazide, Spironolactone Spironolactone W/ Hydrochlorothiazide  1982-05-24   
Hydrochlorothiazide, Bisoprolol Ziac  1993-03-26   
Metoprolol Metoprolol  1994-09-30   
Spironolactone Spironolactone  1982-01-01   
Carvedilol Carvedilol  2007-09-05   
Bisoprolol Bisoprolol  2001-06-26   
Bisoprolol Zebeta  1992-07-31   
Enalapril Enalapril  2000-08-22   
Labetalol Labetalol  1998-09-30   
Losartan potassium Losartan Potassium  2010-04-06   
Ramipril Ramipril  2008-06-18   
Telmisartan Telmisartan Teva  2010-01-25   
Telmisartan Telmisartan Teva Pharma  2011-10-03   
Trandolapril Trandolapril  2006-12-12   
Captopril Captopril  1996-02-13   
Lisinopril Lisinopril  2002-07-01   
Bumetanide Bumetanide  1997-11-18   
Torsemide Torsemide  2002-05-14   
Isosorbide Isosorbide  2000-06-19   
Hydralazine Dralzine  1982-01-01   
Hydralazine Hydralazine  2000-02-23   
Hydroflumethiazide, Reserpine Reserpine Hydroflumethiazide  1985-01-11   
Benazepril, Amlodipine besylate Amlodipine Besylate Benazepril  2007-05-18   
Olmesartan medoxomil, Amlodipine besylate Amlodipine Olmesartan Medoxomil  2016-10-26   
Chlorthalidone Chlorthalidone  1982-01-01   
Propranolol Propranolol  1987-10-07   
Atenolol Atenolol  1993-05-28   
Nadolol Nadolol  1994-08-31   
Indapamide Indapamide  1997-04-04   
Olmesartan medoxomil Olmesartan Medoxomil  2017-04-24   
Novast LaboratoriesMetoprolol Metoprolol  2018-02-06   
Chlorthalidone Chlorthalidone  2017-03-30   
Nadolol Nadolol  2018-06-01   
PadagisNitroglycerin Nitroglycerin  2013-09-20   
Amiloride Midamor  1982-01-01   
Taro PharmaceuticalHydrochlorothiazide, Enalapril Enalapril Hydrochlorothiazide  2001-09-18   
Carvedilol Carvedilol  2007-09-05   
Enalapril Enalapril  2001-01-23   
Bumetanide Bumetanide  2023-07-24   
Glenmark PharmaceuticalsHydrochlorothiazide, Bisoprolol Bisoprolol Hydrochlorothiazide  2022-01-26   
Hydrochlorothiazide, Moexipril Moexipril Hydrochlorothiazide  2010-03-17   
Telmisartan, Hydrochlorothiazide Telmisartan Hydrochlorothiazide  2019-03-04   
Carvedilol Carvedilol  2007-09-05   
Nitroglycerin Nitroglycerin  2017-09-19   
Telmisartan Telmisartan  2014-07-07   
Verapamil, Trandolapril Trandolapril Verapamil  2010-05-05   
Hydralazine Hydralazine  2009-05-29   
Olmesartan medoxomil, Amlodipine besylate Amlodipine Olmesartan Medoxomil  2017-07-05   
Olmesartan medoxomil Olmesartan Medoxomil  2017-05-25   
IngenusIvabradine Ivabradine  2021-12-30   
MylanAmlodipine, Valsartan Amlodipine / Valsartan Mylan  2016-03-22   
Valsartan, Amlodipine besylate Amlodipine Besylate Valsartan  2015-03-30   
Valsartan Valsartan  2015-01-05   
Hydrochlorothiazide, Valsartan Valsartan Hydrochlorothiazide  2012-09-21   
Hydrochlorothiazide, Benazepril Benazepril Hydrochlorothiazide  2004-02-11   
Hydrochlorothiazide, Bisoprolol Bisoprolol Hydrochlorothiazide  2000-09-25   
Hydrochlorothiazide, Candesartan cilexetil Candesartan Cilexetil Hydrochlorothiazide  2012-12-04   
Hydrochlorothiazide, Fosinopril Fosinopril Hydrochlorothiazide  2006-08-14   
Hydrochlorothiazide, Hydralazine, Reserpine Hydralazine Hydrochloride-hydrochlorothiazide-reserpine  1982-01-01   
Hydrochlorothiazide Hydrochlorothiazide  2007-01-23   
Irbesartan, Hydrochlorothiazide Irbesartan Hydrochlorothiazide  2012-09-27   
Hydrochlorothiazide, Lisinopril Lisinopril Hydrochlorothiazide  2002-07-01   
Hydrochlorothiazide, Losartan potassium Losartan Potassium Hydrochlorothiazide  2010-04-06   
Hydrochlorothiazide, Metoprolol Metoprolol Hydrochlorothiazide  2004-08-20   
Hydrochlorothiazide, Quinapril Quinapril Hydrochlorothiazide  2005-03-28   
Hydrochlorothiazide, Spironolactone Spironolactone Hydrochlorothiazide  1982-01-01   
Hydrochlorothiazide, Triamterene Triamterene Hydrochlorothiazide  1996-06-07   
Metoprolol Metoprolol  1993-12-21   
Spironolactone Spironolactone  2001-08-20   
Carvedilol Carvedilol  2007-09-05   
Enalapril Enalapril  2000-08-22   
Nitroglycerin Nitroglycerin  1996-08-30   
Furosemide Furosemide  1986-10-29   
Milrinone Milrinone  2003-06-16   
Losartan potassium Losartan Potassium  2010-10-06   
Candesartan cilexetil Candesartan Cilexetil  2013-05-03   
Metolazone Metolazone  2003-12-23   
Telmisartan Telmisartan  2014-07-07   
Telmisartan, Amlodipine besylate Telmisartan Amlodipine  2014-08-26   
Trandolapril Trandolapril  2008-04-28   
Torsemide Demadex  1993-08-23   
Hydralazine Hydralazine  2010-12-08   
Chlorothiazide Chlorothiazide  1982-01-01   
Chlorothiazide, Reserpine Chlorothiazide-reserpine  1982-05-06   
Benazepril, Amlodipine besylate Amlodipine Besylate Benazepril  2010-05-21   
Chlorthalidone Chlorthalidone  1982-01-01   
Propranolol Propranolol  1985-11-19   
Atenolol Atenolol  1992-01-24   
Esmolol Esmolol  2005-05-02   
Eprosartan Eprosartan  2011-11-16   
NATCO PharmaHydrochlorothiazide, Olmesartan medoxomil Olmesartan Medoxomil Hydrochlorothiazide  2016-10-26   
Telmisartan, Hydrochlorothiazide Telmisartan Hydrochlorothiazide  2014-02-25   
Nitroglycerin Nitroglycerin  2019-04-30   
Ramipril Ramipril  2011-06-30   
Clonidine, Chlorthalidone Clorpres  1987-02-09   
Bendroflumethiazide, Nadolol Nadolol Bendroflumethiazide  2008-02-15   
GSKHydrochlorothiazide, Triamterene Dyazide  1982-01-01   
Hydrochlorothiazide, Labetalol Trandate  1987-04-10   
Digoxin Lanoxicaps  1982-07-26   
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Clinical Trials
Historical Success Rate
Phase 1
70%
66/94
Phase 2
62%
86/139
Phase 3
76%
142/188
Approved: 60Overall Success rate: 33%
All Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Company name
Phase 1
Phase 2
Phase 3
Phase 4
Drug Name
Teva
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