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Company ReportsSpark Therapeutics

Spark Therapeutics(ONCE)

Spark Therapeutics, Inc. is a developer of gene therapy treatments, which treat debilitating genetic diseases. It is a subsidiary of Hoffmann-La Roche.

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Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Luxturna	Voretigene neparvovec	2017-12-19		Retinitis pigmentosa , Leber congenital amaurosis

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Voretigene neparvovec

leber congenital amaurosis

,

retinal dystrophies

,

,

retinitis pigmentosa

brain neoplasms

,

nutritional status

,

,

pneumococcal pneumonia

,

,

male breast neoplasms

,

respiratory tract infections

,

embryo transfer

,

,

,

,

postpartum hemorrhage

,

inflammatory bowel diseases

,

,

tendon injuries

,

,

community-acquired infections

,

haemophilus influenzae

,

streptococcus pneumoniae

,

prostatic neoplasms

,

,

energy metabolism

,

ovarian epithelial carcinoma

,

head and neck neoplasms

,

stomach neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

neoplasms by site

,

non-small-cell lung carcinoma

,

,

falciparum malaria

,

,

renal cell carcinoma

,

colorectal neoplasms

,

,

healthy volunteers/patients

,

,

,

multiple myeloma

,

pancreatic neoplasms

,

uterine cervical neoplasms

,

squamous cell carcinoma of head and neck

,

,

type 1 diabetes mellitus

,

sickle cell anemia

,

sjogren's syndrome

,

,

,

respiration disorders

,

chronic hepatitis b

,

endometrial neoplasms

,

plasma cell neoplasms

,

malignant mesothelioma

,

cutaneous malignant melanoma

,

streptococcus agalactiae

,

follicular lymphoma

,

microsatellite repeats

,

small cell lung carcinoma

,

macular degeneration

,

b-cell lymphoma

,

,

,

,

respiratory tract diseases

,

,

focal segmental glomerulosclerosis

,

cytomegalovirus infections

,

membranous glomerulonephritis

,

nephrotic syndrome

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

systemic scleroderma

,

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

,

,

,

kidney transplantation

,

,

,

,

b-cell chronic lymphocytic leukemia

,

beta-thalassemia

,

,

sickle cell trait

,

,

,

clear cell adenocarcinoma

,

large cell carcinoma

,

vaginal neoplasms

,

vulvar neoplasms

,

,

breast neoplasms

,

,

rheumatoid arthritis

,

ovarian neoplasms

,

haemophilus influenzae type b

,

haemophilus infections

,

,

chronic renal insufficiency

,

,

neisseria meningitidis

,

respiratory syncytial virus infections

,

streptococcal infections

,

,

muscle spasticity

,

kidney diseases

,

postmenopausal osteoporosis

,

non-hodgkin lymphoma

,

,

human influenza

,

,

,

insulin resistance

,

pneumococcal infections

,

thrombocytopenic purpura idiopathic

,

inflammatory breast neoplasms

,

ductal carcinoma breast

,

,

,

,

abdominal obesity

,

,

,

,

chronic kidney failure

,

,

large b-cell lymphoma diffuse

,

,

renal insufficiency

,

systemic lupus erythematosus

,

myocardial infarction

,

st elevation myocardial infarction

,

acute coronary syndrome

,

,

,

left ventricular hypertrophy

,

rotavirus infections

,

,

,

meningococcal infections

,

,

mucinous adenocarcinoma

,

,

meningococcal meningitis

,

,

thrombocytopenia

,

respiratory syncytial viruses

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

,

,

chronic obstructive pulmonary disease

,

acquired immunodeficiency syndrome

,

,

,

,

,

metabolic bone diseases

,

obstructive lung diseases

,

pulmonary eosinophilia

,

,

,

chronic bronchitis

,

,

chronic disease

,

growth and development

,

,

,

immunologic tests

,

,

alzheimer disease

,

cardiovascular diseases

,

wasting syndrome

,

,

lipid metabolism

,

resistance training

,

,

,

major depressive disorder

,

depressive disorder

,

,

allergic rhinitis seasonal

,

clostridioides difficile

Globulin, immune

healthy volunteers/patients

,

myeloid leukemia acute

,

myelodysplastic syndromes

,

macular degeneration

,

,

,

monoclonal gammopathy of undetermined significance

,

myeloid leukemia

,

,

soft tissue neoplasms

,

,

chronic hepatitis b

,

,

,

herpesviridae infections

,

,

myeloproliferative disorders

,

,

plasmablastic lymphoma

,

large-cell lymphoma immunoblastic

,

,

renal cell carcinoma

,

urologic neoplasms

,

kidney neoplasms

,

neoplasm metastasis

,

primary myelofibrosis

,

precursor cell lymphoblastic leukemia-lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

hodgkin disease

,

aplastic anemia

,

gastrointestinal neoplasms

,

,

prostatic neoplasms

,

non-small-cell lung carcinoma

,

hematologic neoplasms

,

,

hidradenitis suppurativa

,

smoldering multiple myeloma

,

immunoglobulin light-chain amyloidosis

,

renal insufficiency

,

atopic dermatitis

,

,

,

,

,

paraproteinemias

,

,

,

castration-resistant prostatic neoplasms

,

,

ovarian neoplasms

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

adenocarcinoma of lung

,

biliary liver cirrhosis

,

peripheral arterial disease

,

castleman disease

,

alzheimer disease

,

,

cognitive dysfunction

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

hematologic diseases

,

bone marrow diseases

,

,

cytokine release syndrome

,

small cell carcinoma

,

small cell lung carcinoma

,

neuroendocrine carcinoma

,

,

,

,

,

diffuse intrinsic pontine glioma

,

optic nerve glioma

,

brain stem neoplasms

,

,

acquired immunodeficiency syndrome

,

retroviridae infections

,

viral sexually transmitted diseases

,

pancreatic neoplasms

,

triple negative breast neoplasms

,

sickle cell anemia

,

residual neoplasm

,

plasma cell neoplasms

,

rheumatoid arthritis

,

non-hodgkin lymphoma

,

b-cell lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

large b-cell lymphoma diffuse

,

juvenile arthritis

,

,

colorectal neoplasms

,

systemic lupus erythematosus

,

follicular lymphoma

,

mantle-cell lymphoma

,

axial spondyloarthritis

,

,

lymphoid leukemia

,

waldenstrom macroglobulinemia

,

b-cell lymphoma marginal zone

,

,

prolymphocytic leukemia t-cell

,

neonatal alloimmune thrombocytopenia

,

,

multiple myeloma

,

,

,

,

psoriatic arthritis

,

ulcerative colitis

,

,

ankylosing spondylitis

,

inflammatory bowel diseases

,

spondylarthropathies

,

spondylarthritis

,

,

cardiovascular diseases

,

chronic kidney failure

,

pure red-cell aplasia

,

,

kidney diseases

,

,

congenital abnormalities

,

autoimmune diseases

,

,

lymphoproliferative disorders

Lambda-cyhalothrin

,

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