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Revance Therapeutics
Revance Therapeutics
(RVNC)
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Daxxify
Botulinum toxin type a
2022-09-07
Genetic skin diseases
,
Dystonia
,
Fissure in ano
,
Strabismus
,
Blepharospasm
,
Muscle rigidity
,
Skin aging
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Botulinum toxin type a
paralysis
,
hemorrhagic stroke
,
complex regional pain syndromes
,
skin abnormalities
,
facial expression
,
thrombosis
,
intracranial sinus thrombosis
,
internal carotid artery dissection
,
vertebral artery dissection
,
vascular headaches
,
affect
,
leukemia
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
myeloid leukemia
,
preleukemia
,
gingival overgrowth
,
treatment-resistant depressive disorder
,
secondary headache disorders
,
vasculogenic impotence
,
feeding behavior
,
darier disease
,
benign familial pemphigus
,
heart arrest
,
seborrheic dermatitis
,
sarcoma
,
liposarcoma
,
myxoid liposarcoma
,
stress fractures
,
psychological stress
,
physiological stress
,
neurological rehabilitation
,
cystitis
,
parkinsonian disorders
,
alopecia areata
,
diabetes mellitus
,
muscle cramp
,
headache disorders
,
cleft lip
,
neck pain
,
muscle hypertonia
,
carpal tunnel syndrome
,
restless legs syndrome
,
contracture
,
prostatic neoplasms
,
neuroma
,
acne vulgaris
,
alopecia
,
facial neuralgia
,
therapeutics
,
chronic disease
,
tendinopathy
,
morbid obesity
,
low anterior resection syndrome
,
obstructive sleep apnea
,
snoring
,
ischemia
,
sleep apnea syndromes
,
atopic dermatitis
,
eczema
,
dermatitis
,
ventricular tachycardia
,
tachycardia
,
voice disorders
,
hemorrhoids
,
type 2 diabetes mellitus
,
magnetic resonance imaging
,
popliteal artery entrapment syndrome
,
ganglion cysts
,
radiation injuries
,
burning mouth syndrome
,
nasal polyps
,
bites and stings
,
rhinitis
,
borderline personality disorder
,
rotator cuff tear arthropathy
,
postoperative complications
,
migraine with aura
,
cleft palate
,
atrial flutter
,
psychomotor agitation
,
cancer pain
,
tardive dyskinesia
,
stomach neoplasms
,
laryngeal granuloma
,
granuloma
,
rectal neoplasms
,
endometriosis
,
pudendal neuralgia
,
lacrimal apparatus diseases
,
renal cell carcinoma
,
malformed nails
,
pachyonychia congenita
,
penile induration
,
atrophic rhinitis
,
myocardial ischemia
,
dementia
,
muscle rigidity
,
caregiver burden
,
abdominoplasty
,
musculoskeletal pain
,
scoliosis
,
pancreatic neoplasms
,
inflammation
,
neurogenic inflammation
,
recreational drug use
,
chronic obstructive pulmonary disease
,
photophobia
,
vascular system injuries
,
food hypersensitivity
,
sensation disorders
,
xerostomia
,
piriformis muscle syndrome
,
traumatic brain injuries
,
sialorrhea
,
lower urinary tract symptoms
,
obesity
,
atrial fibrillation
,
tennis elbow
,
spasm
,
vulvodynia
,
fecal incontinence
,
erectile dysfunction
,
strabismus
,
somatoform disorders
,
deglutition disorders
,
myalgia
,
weight loss
,
constipation
,
systemic scleroderma
,
diffuse scleroderma
,
esophageal motility disorders
,
urologic diseases
,
urinary bladder diseases
,
amyotrophic lateral sclerosis
,
premature ejaculation
,
gastroparesis
,
cluster headache
,
chronic exertional compartment syndrome
,
esophageal neoplasms
,
pruritus
,
nervous system diseases
,
epidermolysis bullosa simplex
,
epidermolysis bullosa
,
neonatal brachial plexus palsy
,
physiological sexual dysfunction
,
dry eye syndromes
,
migraine without aura
,
paraplegia
,
hyperalgesia
,
hereditary sensory and autonomic neuropathies
,
arthritis
,
arthralgia
,
motor neuron disease
,
procedural pain
,
premature birth
,
sinusitis
,
rhinosinusitis
,
cardiac surgical procedures
,
neoplasm metastasis
,
electromyography
,
beckwith-wiedemann syndrome
,
trigeminal nerve injuries
,
acrodynia
,
hammer toe syndrome
,
urinary retention
,
hereditary hemorrhagic telangiectasia
,
intellectual disability
,
brain concussion
,
hereditary breast and ovarian cancer syndrome
,
hip dislocation
,
hyperpigmentation
,
cone-rod dystrophies
,
knee injuries
,
patellofemoral pain syndrome
,
congenital lower extremity deformities
,
eye diseases
,
bronchiolitis obliterans syndrome
,
hereditary spastic paraplegia
,
tension-type headache
,
hyperplasia
,
meige syndrome
,
thromboangiitis obliterans
,
hematuria
,
local anesthesia
,
liver diseases
,
esophageal diseases
,
esophagectomy
,
dysmenorrhea
,
muscle spasticity
,
overactive urinary bladder
,
stroke
,
cerebral palsy
,
torticollis
,
migraine disorders
,
dystonia
,
dystonic disorders
,
urinary incontinence
,
pain
,
blepharospasm
,
urge urinary incontinence
,
hemiplegia
,
bruxism
,
hyperhidrosis
,
neurogenic urinary bladder
,
spinal cord injuries
,
interstitial cystitis
,
clostridium botulinum type a
,
temporomandibular joint disorders
,
clostridium botulinum
,
multiple sclerosis
,
headache
,
syndrome
,
parkinson disease
,
skin aging
,
cicatrix
,
facial pain
,
neuralgia
,
healthy volunteers/patients
,
paresis
,
botulism
,
prostatic hyperplasia
,
dysphonia
,
fissure in ano
,
myofascial pain syndromes
,
temporomandibular joint dysfunction syndrome
,
brain injuries
,
plantar fasciitis
,
hemifacial spasm
,
chronic pain
,
hypertrophic cicatrix
,
enuresis
,
urinary tract infections
,
osteoarthritis
,
raynaud disease
,
tremor
,
postoperative pain
,
sleep bruxism
,
essential tremor
,
facies
,
sclerosis
,
facial paralysis
,
keloid
,
knee osteoarthritis
,
pelvic pain
,
esotropia
,
trigeminal neuralgia
,
low back pain
,
wounds and injuries
,
depression
,
pelvic floor disorders
,
clubfoot
,
hoarseness
,
shoulder pain
,
ventral hernia
,
hypertrophy
,
aging
,
synkinesis
,
compartment syndromes
,
esophageal achalasia
,
fibromyalgia
,
breast neoplasms
,
smiling
,
anxiety disorders
,
abdominal hernia
,
stress urinary incontinence
,
fasciitis
,
post-traumatic headache
,
major depressive disorder
,
rosacea
,
vaginismus
,
back pain
,
lacerations
,
neoplasms
,
postherpetic neuralgia
,
hernia
,
incisional hernia
,
breast diseases
,
vomiting
,
infections
,
diabetic neuropathies
,
dyspareunia
,
anxiety
,
vulvar vestibulitis
,
agnosia
,
psoriasis
,
skin diseases
,
thoracic outlet syndrome
,
prostatitis
,
hidradenitis suppurativa
,
joint diseases
,
prolapse
,
open abdomen techniques
,
hyperkinesis
,
abnormal reflex
,
nausea
,
hallux valgus
,
flushing
,
foot deformities
,
autonomic dysreflexia
,
esthetics
,
muscular atrophy
,
exotropia
,
blepharoptosis
,
skin neoplasms
,
atrophy
,
graves ophthalmopathy
,
injection site reaction
,
peripheral nerve injuries
,
vulvar diseases
,
rejuvenation
,
head and neck neoplasms
,
pelvic organ prolapse
,
nocturia
,
postoperative nausea and vomiting
,
bariatric surgery
,
social phobia
,
facial nerve injuries
,
facial asymmetry
,
stroke rehabilitation
,
neurodegenerative diseases
,
blushing
,
shock
,
diabetes insipidus
,
neoplasms by site
,
drug-related side effects and adverse reactions
,
polyneuropathies
,
vitiligo
,
multiple system atrophy
,
leg length inequality
,
developmental disabilities
,
meningomyelocele
,
brachial plexus neuritis
,
seizures
,
antibiotic prophylaxis
,
whiplash injuries
,
cerebrovascular disorders
,
urodynamics
,
trismus
,
blood circulation
,
contusions
,
ecchymosis
,
basal cell carcinoma
,
melanoma
,
squamous cell carcinoma
,
squamous cell neoplasms
,
basal cell neoplasms
,
equinus deformity
,
ultrasonography
,
neurologic gait disorders
,
ischemic stroke
,
talipes
,
diffuse esophageal spasm
,
motor activity
,
peripheral nervous system diseases
,
rare diseases
,
movement disorders
,
cutis laxa
,
bell palsy
,
gingival recession
,
urinary bladder neck obstruction
,
activities of daily living
,
internal hernia
,
pancreatic fistula
,
pancreatectomy
,
treatment outcome
,
muscle tonus
,
gastroesophageal reflux
,
endoscopy
,
physical therapy modalities
,
anticholinergic syndrome
,
erythema
,
intravesical administration
,
hellp syndrome
,
congenital abnormalities
,
congenital foot deformities
,
ocular motility disorders
,
spinal stenosis
,
tourette syndrome
,
tics
,
sexuality
,
keratoconus
,
chest pain
,
neurologic manifestations
,
mumps
,
urination disorders
,
female urogenital diseases
,
female urogenital diseases and pregnancy complications
,
herpes labialis
,
foot ulcer
,
muscle strength
,
dyspepsia
,
gastrointestinal diseases
,
motor disorders
,
feeding and eating disorders
,
respiratory aspiration
,
inhalation anesthesia
,
optic atrophy
,
metrorrhagia
,
rehabilitation
,
ataxia
,
defecation
,
respiratory insufficiency
,
craniomandibular disorders
,
cosmetic techniques
,
bite force
,
tooth wear
,
lens subluxation
,
chronic brain injury
,
primary headache disorders
,
dystonia musculorum deformans
,
muscle contraction
,
communicable diseases
,
metabolic bone diseases
,
sarcopenia
,
pathologic neovascularization
,
brain stem infarctions
,
arm injuries
,
professional burnout
,
surgical wound
,
transurethral resection of prostate
,
nocturnal enuresis
,
diurnal enuresis
,
postoperative period
,
hepatolenticular degeneration
,
shoulder injuries
,
self concept
,
craniocerebral trauma
,
only child
,
sickle cell anemia
,
hemoglobinopathies
,
reflex sympathetic dystrophy
,
causalgia
,
phantom limb
,
intra-articular injections
,
habits
,
gingival diseases
,
dental esthetics
Benzocaine
type 1 diabetes mellitus
,
neoplasms
,
hypoglycemia
,
liver diseases
,
type 2 diabetes mellitus
,
hepatitis c
,
hepatitis
,
hepatitis a
,
movement disorders
,
central nervous system diseases
,
brain diseases
,
neurodegenerative diseases
,
glucose metabolism disorders
,
metabolic diseases
,
endocrine system diseases
,
drug-induced akathisia
,
nervous system diseases
,
chronic hepatitis
,
parkinsonian disorders
,
drug-induced dyskinesia
,
postoperative pain
,
osteoarthritis
,
neuralgia
,
postherpetic neuralgia
,
liver cirrhosis
,
fibrosis
,
hiv
,
castration-resistant prostatic neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
alzheimer disease
,
dementia
,
thyroid neoplasms
,
thyroid diseases
,
parkinson disease
,
diabetes mellitus
,
chronic hepatitis c
,
hiv infections
,
acquired immunodeficiency syndrome
,
hiv-2
,
immunologic deficiency syndromes
,
small cell lung carcinoma
,
hypertension
,
coronary artery disease
,
myocardial ischemia
,
dyslipidemias
,
atherosclerosis
,
rheumatoid arthritis
,
arthritis
,
polycythemia vera
,
neuromuscular blockade
,
prostatic neoplasms
,
anesthesia
,
obesity
,
chronic renal insufficiency
,
acute coronary syndrome
,
kidney diseases
,
leiomyoma
,
endometriosis
,
cholecystitis
,
uterine prolapse
,
intestinal obstruction
,
prolapse
,
spinal diseases
,
delayed emergence from anesthesia
,
laryngoscopy
,
laparoscopy
,
muscle relaxation
,
disease
,
gastric bypass
,
respiration
,
urinary retention
,
infertility
,
female infertility
,
uterine diseases
,
postoperative complications
,
pneumonia
,
wound infection
,
surgical wound infection
Histidine
streptococcal infections
,
haemophilus infections
,
malaria
,
falciparum malaria
,
covid-19
Aspartame
prostatic hyperplasia
,
healthy volunteers/patients
,
respiratory tract diseases
,
respiration disorders
,
hyperhidrosis
,
kidney diseases
,
obesity
,
weight loss
,
burns
,
bronchiectasis
,
respiratory tract infections
,
skin diseases
,
premature obstetric labor
,
heart failure
,
pulmonary edema
,
amyloidosis
,
bacterial infections
,
liver diseases
,
hepatic insufficiency
,
sepsis
,
non-alcoholic fatty liver disease
,
neoplasms
,
multiple myeloma
,
common cold
,
tuberculosis
,
recurrence
,
breast neoplasms
,
rhinitis
,
pulmonary tuberculosis
,
atherosclerosis
,
obstructive lung diseases
,
plasma cell neoplasms
,
virus diseases
,
pancreatic neoplasms
,
lymphoma
,
follicular lymphoma
,
allergic rhinitis
,
coronary disease
,
coronary artery disease
,
myocardial ischemia
,
heart diseases
,
carcinoma
,
hepatocellular carcinoma
,
liver neoplasms
,
precursor cell lymphoblastic leukemia-lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
sjogren's syndrome
,
xerostomia
,
ulcer
,
buruli ulcer
,
hiv infections
,
systemic lupus erythematosus
,
malaria
,
infections
,
acquired immunodeficiency syndrome
,
vivax malaria
,
type 2 diabetes mellitus
,
human influenza
,
communicable diseases
,
hemolysis
,
bone fractures
,
parkinson disease
,
pemphigus
,
migraine disorders
,
depression
,
major depressive disorder
,
depressive disorder
,
churg-strauss syndrome
,
granulomatosis with polyangiitis
,
systemic vasculitis
,
eosinophilic granuloma
,
neisseria meningitidis
,
haemophilus influenzae type b
,
restless legs syndrome
,
psychomotor agitation
,
syndrome
,
hypereosinophilic syndrome
,
covid-19
,
arthralgia
,
ovarian neoplasms
,
ovarian epithelial carcinoma
,
anthrax
,
urinary tract infections
,
pyelonephritis
,
respiratory syncytial virus infections
,
asthma
,
chronic obstructive pulmonary disease
,
lung diseases
,
diabetes mellitus
,
hepatitis
,
hepatitis a
,
nausea
,
pulmonary eosinophilia
,
prostatic neoplasms
,
autoimmune diseases
,
hyperplasia
,
growth and development
,
neuralgia
,
herpes zoster
,
postherpetic neuralgia
,
herpes simplex
Bevifimod
healthy volunteers/patients
,
factor vii deficiency
,
psoriasis
,
hidradenitis suppurativa
,
chronic kidney failure
,
diabetes mellitus
,
diffuse scleroderma
,
thrombosis
,
systemic scleroderma
,
rheumatoid arthritis
,
chronic obstructive pulmonary disease
,
soft tissue infections
,
necrotizing fasciitis
,
fournier gangrene
,
gas gangrene
,
raynaud disease
,
wounds and injuries
,
myasthenia gravis
,
cardiac surgical procedures
,
covid-19
,
eosinophilic esophagitis
,
postpartum hemorrhage
,
acute kidney injury
,
sickle cell anemia
,
acute chest syndrome
,
vaso-occlusive crises
,
hemophilia a
,
agammaglobulinemia
,
common variable immunodeficiency
,
graft vs host disease
,
hereditary angioedemas
,
afibrinogenemia
,
blood coagulation disorders
,
ischemic stroke
,
stroke
,
coronary artery disease
,
heart diseases
,
atherosclerosis
,
heart valve diseases
,
chronic inflammatory demyelinating polyradiculoneuropathy
,
kidney transplantation
,
igg deficiency
,
von willebrand diseases
,
hemostatic disorders
,
postoperative hemorrhage
,
dermatomyositis
,
atrial fibrillation
,
heart failure
,
hypertension
,
cardiovascular diseases
,
acute coronary syndrome
,
hemorrhagic stroke
,
peripheral arterial disease
,
central nervous system diseases
,
central nervous system infections
,
encephalomyelitis
,
encephalitis
,
meningoencephalitis
,
acquired immunodeficiency syndrome
,
job syndrome
,
factor xiii deficiency
,
thrombocytopenia
,
hematologic neoplasms
,
multiple myeloma
,
b-cell chronic lymphocytic leukemia
,
burkitt lymphoma
,
hemophilia b
,
primary immunodeficiency diseases
,
hemorrhage
,
hereditary angioedema types i and ii
,
alpha 1-antitrypsin deficiency
,
surgical blood loss
,
immunologic deficiency syndromes
,
thrombocytopenic purpura idiopathic
,
emphysema
,
cardiovascular surgical procedures
,
tropical spastic paraparesis
,
thromboembolism
,
sclerosis
,
pneumococcal infections
,
otitis media
,
streptococcal infections
,
bacterial pneumonia
,
bacterial meningitis
,
haemophilus influenzae
,
hereditary complement deficiency diseases
,
neisseriaceae infections
,
infections
,
lung diseases
,
ataxia
,
communicable diseases
,
ataxia telangiectasia
,
telangiectasis
,
x-linked combined immunodeficiency diseases
,
cerebellar ataxia
Trehalose
ovarian neoplasms
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
Azzalure
complex regional pain syndromes
,
pelvic pain
,
dyspareunia
,
vaginismus
,
psoriasis
,
chronic pain
,
stress urinary incontinence
,
osteoarthritis
,
prostatic hyperplasia
,
neuralgia
,
magnetic resonance imaging
,
therapeutics
,
joint diseases
,
hypertrophic cicatrix
,
pruritus
,
major depressive disorder
,
carpal tunnel syndrome
,
premature ejaculation
,
hyperalgesia
,
rectal neoplasms
,
low anterior resection syndrome
,
cicatrix
,
penile induration
,
thoracic outlet syndrome
,
postherpetic neuralgia
,
motor neuron disease
,
cerebral palsy
,
dystonic disorders
,
myofascial pain syndromes
,
shoulder pain
,
prostatitis
,
arthritis
,
arthralgia
,
temporomandibular joint disorders
,
facial pain
,
acrodynia
,
somatoform disorders
,
essential tremor
,
systemic scleroderma
,
raynaud disease
,
diffuse scleroderma
,
urinary bladder diseases
,
multiple sclerosis
,
breast neoplasms
,
neoplasms
,
postoperative pain
,
breast diseases
,
hereditary breast and ovarian cancer syndrome
,
sialorrhea
,
paresis
,
knee injuries
,
patellofemoral pain syndrome
,
constipation
,
muscle spasticity
,
overactive urinary bladder
,
urinary incontinence
,
migraine disorders
,
stroke
,
torticollis
,
hyperhidrosis
,
headache
,
dystonia
,
blepharospasm
,
parkinson disease
,
skin aging
,
neurogenic urinary bladder
,
brain injuries
,
pain
,
healthy volunteers/patients
,
enuresis
,
aging
,
interstitial cystitis
,
drug-related side effects and adverse reactions
,
graves ophthalmopathy
,
depression
,
bruxism
,
spinal cord injuries
,
developmental disabilities
,
postoperative nausea and vomiting
,
bariatric surgery
,
vomiting
,
nausea
,
traumatic brain injuries
,
herpes labialis
,
strabismus
,
diabetes mellitus
,
neck pain
,
back pain
,
dysphonia
,
abnormal reflex
,
muscle strength
,
clostridium botulinum type a
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