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Ocuphire Pharma

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Ryzumvi	Phentolamine	2023-09-25	2034-2039	Necrosis , Extravasation of diagnostic and therapeutic materials , Malignant hypertension

Clinical Trials

Therapeutic Areas:

All

Classification:

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Approval:

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Status:

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Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

healthy volunteers/patients

,

,

type 1 diabetes mellitus

,

,

chronic obstructive pulmonary disease

,

pulmonary arterial hypertension

,

obstructive lung diseases

,

vasculogenic impotence

,

stem cell transplantation

,

insulin resistance

,

cardiovascular diseases

,

obstructive sleep apnea

,

sleep apnea syndromes

,

erectile dysfunction

,

prostatic neoplasms

,

ocular hypertension

,

,

open-angle glaucoma

,

,

,

pathologic dilatation

,

,

,

,

,

,

drug-related side effects and adverse reactions

,

ischemic stroke

,

,

vision disorders

,

respiratory distress syndrome

,

coronavirus infections

,

respiratory insufficiency

,

acute lung injury

,

,

newborn respiratory distress syndrome

,

soft tissue injuries

,

acute kidney injury

,

wounds and injuries

,

acute coronary syndrome

,

coronary artery disease

,

night blindness

,

,

,

dental anesthesia

,

local anesthesia

,

vasoconstriction

,

,

,

multiple myeloma

,

plasma cell neoplasms

,

neoplasm metastasis

,

pregnancy complications

,

,

cerebral hemorrhage

,

,

intracranial hemorrhages

,

diabetes mellitus

,

,

,

preoperative period

,

,

,

,

,

,

pulmonary aspergillosis

,

,

invasive candidiasis

,

Clavulanic acid

healthy volunteers/patients

,

chemical and drug induced liver injury

,

,

therapeutic equivalency

,

prosthesis-related infections

,

,

brain neoplasms

,

,

,

pulmonary tuberculosis

,

cocaine-related disorders

,

,

colorectal neoplasms

,

,

,

,

major depressive disorder

,

depressive disorder

,

erectile dysfunction

,

,

colonic neoplasms

,

,

pelvic infection

,

pelvic inflammatory disease

,

pleural effusion

,

tobacco use disorder

,

substance-related disorders

,

,

diabetes mellitus

,

,

pancreatic fistula

,

bacterial pneumonia

,

intraabdominal infections

,

,

,

,

,

,

,

acalculous cholecystitis

,

,

,

community-acquired infections

,

,

,

,

,

,

head and neck neoplasms

,

enterobacteriaceae infections

,

,

environmental biomarkers

,

helicobacter infections

,

maxillary sinusitis

,

,

alcoholic liver diseases

,

,

,

alcoholic hepatitis

,

chronic renal insufficiency

,

kidney diseases

,

congenital abnormalities

,

vesico-ureteral reflux

,

,

,

intestinal obstruction

,

peptic ulcer perforation

,

cross infection

,

,

abdominal abscess

,

,

intestinal perforation

,

,

,

,

catheter-related infections

,

,

induced hypothermia

,

suppurative otitis media

,

cholecystectomy

,

central nervous system neoplasms

,

intestinal neoplasms

,

nervous system neoplasms

,

bites and stings

,

disease progression

,

hematologic neoplasms

,

agammaglobulinemia

,

,

incisional hernia

,

osteoradionecrosis

,

,

,

communicable diseases

,

,

,

,

,

,

,

urinary tract infections

,

,

surgical wound infection

,

bacterial infections

,

wound infection

,

respiratory tract infections

,

,

,

wounds and injuries

,

,

,

,

,

,

chronic bronchitis

,

febrile neutropenia

,

,

,

postoperative complications

,

chronic obstructive pulmonary disease

,

,

,

,

ventilator-associated pneumonia

,

,

mandibular fractures

,

,

,

,

obstructive lung diseases

,

antibiotic prophylaxis

,

,

multidrug-resistant tuberculosis

,

cystic fibrosis

,

infectious arthritis

,

postoperative pain

,

staphylococcal infections

,

,

bacterial skin diseases

,

,

,

,

,

tooth extraction

,

,

aspiration pneumonia

,

soft tissue infections

,

urinary bladder neoplasms

,

,

liver cirrhosis

,

overactive urinary bladder

,

,

dental pulp necrosis

,

,

,

,

streptococcal infections

,

dental focal infection

,

focal infection

,

surgical amputation

,

temporomandibular joint disorders

,

temporomandibular joint dysfunction syndrome

,

obstructive sleep apnea

,

sleep apnea syndromes

,

,

,

,

prostatic neoplasms

,

neurogenic urinary bladder

,

bacterial eye infections

,

neonatal sepsis

,

out-of-hospital cardiac arrest

,

,

,

atrial fibrillation

,

,

venous thrombosis

,

pulmonary embolism

,

,

infectious skin diseases

,

respiratory aspiration

,

surgical wound dehiscence

,

,

,

,

,

pulmonary infarction

,

gastroenteritis

,

,

urinary diversion

,

pharmacokinetics

,

bisphosphonate-associated osteonecrosis of the jaw

,

acute cholecystitis

,

,

,

,

,

,

,

periapical periodontitis

,

alveolar bone loss

,

,

,

disease susceptibility

,

subcutaneous injections

,

,

critical illness

,

spontaneous abortion

,

incomplete abortion

,

peritonsillar abscess

,

ulcerative colitis

,

,

,

chronic kidney failure

,

renal insufficiency

,

continuous renal replacement therapy

,

penicillin resistance

,

capillary leak syndrome

,

electric impedance

,

,

myelodysplastic syndromes

,

myeloproliferative disorders

,

multiple myeloma

,

precancerous conditions

,

myelodysplastic-myeloproliferative diseases

,

plasma cell neoplasms

,

,

,

,

,

,

pregnancy complications

,

,

bone resorption

,

esophageal motility disorders

,

esophageal achalasia

,

diffuse esophageal spasm

,

esophageal diseases

,

motor disorders

,

,

abdominal hernia

,

internal hernia

,

,

,

,

asymptomatic diseases

,

,

,

,

orbital fractures

,

orbital cellulitis

,

methicillin-resistant staphylococcus aureus

,

,

human influenza

,

respiratory syncytial viruses

,

,

,

,

anastomotic leak

,

laparoscopic cholecystectomy

,

,

,

supernumerary tooth

,

dental implants

,

pharmacokinetics

,

chronic kidney failure

,

renal insufficiency

,

cerebral ventriculitis

,

cerebrospinal fluid shunts

,

ventriculoperitoneal shunt

,

retinal diseases

,

aids-related complex

,

,

mandibular fractures

,

viral pneumonia

,

,

,

,

,

,

breast neoplasms

,

,

prostatic neoplasms

,

,

chlamydia infections

,

,

erectile dysfunction

,

bipolar disorder

,

,

ovarian epithelial carcinoma

,

male breast neoplasms

,

,

invasive hydatidiform mole

,

,

ulcerative colitis

,

inflammatory bowel diseases

,

,

subacute bacterial endocarditis

,

parkinson disease

,

,

pelvic infection

,

pelvic inflammatory disease

,

,

psychotic disorders

,

mental disorders

,

fallopian tube neoplasms

,

,

synovial sarcoma

,

,

rhabdomyosarcoma

,

primitive neuroectodermal tumors

,

primitive neuroectodermal tumors peripheral

,

alveolar rhabdomyosarcoma

,

,

embryonal rhabdomyosarcoma

,

neuroectodermal tumors

,

renal cell carcinoma

,

endometrial neoplasms

,

endometrioid carcinoma

,

non-hodgkin lymphoma

,

,

follicular lymphoma

,

mantle-cell lymphoma

,

large b-cell lymphoma diffuse

,

large-cell lymphoma anaplastic

,

burkitt lymphoma

,

brain neoplasms

,

,

,

,

,

salivary gland neoplasms

,

head and neck neoplasms

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

oropharyngeal neoplasms

,

unknown primary neoplasms

,

squamous cell neoplasms

,

tongue neoplasms

,

laryngeal neoplasms

,

verrucous carcinoma

,

paranasal sinus neoplasms

,

laryngeal diseases

,

bile duct neoplasms

,

liver neoplasms

,

cholangiocarcinoma

,

gallbladder neoplasms

,

urinary bladder neoplasms

,

kidney neoplasms

,

urethral neoplasms

,

transitional cell carcinoma

,

ureteral neoplasms

,

,

pulmonary tuberculosis

,

hematologic neoplasms

,

bacillary dysentery

,

tibial meniscus injuries

,

cartilage fractures

,

,

cardiovascular diseases

,

ischemic stroke

,

,

cerebrovascular disorders

,

central nervous system diseases

,

,

nervous system diseases

,

,

cephalosporin resistance

,

enterobacteriaceae infections

,

,

,

,

chronic hepatitis c

,

,

,

,

,

bacterial endocarditis

,

severe acute malnutrition

,

post-lyme disease syndrome

,

,

bacterial skin diseases

,

kidney diseases

,

systemic inflammatory response syndrome

,

microbial drug resistance

,

bacterial drug resistance

,

methicillin-resistant staphylococcus aureus

,

pseudomonas infections

,

esophageal achalasia

,

,

hepatocellular carcinoma

,

antibiotic prophylaxis

,

uterine cervicitis

,

,

,

environmental biomarkers

,

escherichia coli infections

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

hemopneumothorax

,

,

,

chronic renal insufficiency

,

congenital abnormalities

,

vesico-ureteral reflux

,

chronic obstructive pulmonary disease

,

disease progression

,

,

acquired immunodeficiency syndrome

,

child nutrition disorders

,

hidradenitis suppurativa

,

,

asymptomatic diseases

,

,

communicable diseases

,

,

healthy volunteers/patients

,

,

bacterial infections

,

urinary tract infections

,

bacterial pneumonia

,

critical illness

,

intraabdominal infections

,

,

,

hypersensitivity

,

,

ventilator-associated pneumonia

,

cystic fibrosis

,

,

healthcare-associated pneumonia

,

,

,

gram-negative bacterial infections

,

staphylococcal infections

,

,

,

,

surgical wound infection

,

,

soft tissue infections

,

,

,

,

respiratory tract infections

,

,

,

,

,

infectious arthritis

,

,

lyme neuroborreliosis

,

febrile neutropenia

,

drug hypersensitivity

,

,

,

liver cirrhosis

,

wound infection

,

,

,

,

,

,

community-acquired infections

,

bacterial vaginosis

,

chronic bronchitis

,

,

bacterial meningitis

,

central nervous system infections

,

,

,

staphylococcal skin infections

,

infectious skin diseases

,

,

,

,

pyogenic liver abscess

,

klebsiella infections

,

gastrointestinal hemorrhage

,

,

,

cross infection

,

wounds and injuries

,

,

immediate hypersensitivity

,

drug-related side effects and adverse reactions

,

premature birth

,

,

adaptive immunity

,

nephrolithiasis

,

,

diabetes mellitus

,

,

esophageal and gastric varices

,

pneumococcal pneumonia

,

abdominal abscess

,

acalculous cholecystitis

,

pregnancy complications

,

postpartum hemorrhage

,

pituitary neoplasms

,

,

pituitary diseases

,

pseudomonas aeruginosa

,

,

peritoneal dialysis

,

,

otitis media with effusion

,

,

,

neisseria gonorrhoeae

,

respiratory aspiration

,

aspiration pneumonia

,

,

substance-related disorders

,

intravenous substance abuse

,

pulmonary infarction

,

gastroenteritis

,

pulmonary fibrosis

,

,

,

premature rupture fetal membranes

,

,

high-risk pregnancy

,

drug monitoring

,

acute kidney injury

,

,

newborn respiratory distress syndrome

,

neurotoxicity syndromes

,

penicillin resistance

,

respiratory distress syndrome

,

,

streptococcal infections

,

replacement arthroplasty hip

,

,

,

coronavirus infections

,

,

,

,

,

blood coagulation disorders

,

mucocutaneous lymph node syndrome

,

hyperaldosteronism

,

pulmonary arterial hypertension

,

hyperphosphatemia

,

,

,

sleep initiation and maintenance disorders

,

cardiac arrhythmias

,

bronchopulmonary dysplasia

,

adrenal insufficiency

,

,

hemostatic disorders

,

,

coagulation protein disorders

,

attention deficit disorder with hyperactivity

,

,

,

,

disease susceptibility

,

,

propionibacterium acnes

,

aseptic meningitis

,

benign migratory glossitis

,

erythema chronicum migrans

,

,

,

depressive disorder

,

salmonella infections

,

hiv seropositivity

,

,

hemodiafiltration

,

continuous renal replacement therapy

,

gram-positive bacterial infections

,

,

digestive system fistula

,

retinal detachment

,

dissociative disorders

,

,

,

menstruation disturbances

,

,

protein-energy malnutrition

,

,

nut hypersensitivity

,

,

delayed hypersensitivity

,

streptococcus agalactiae

,

recreational drug use

,

postoperative complications

,

laboratory infection

,

acute lung injury

,

,

,

,

hip osteoarthritis

,

,

cardiogenic shock

,

,

acinetobacter baumannii

,

retinal diseases

,

diabetic retinopathy

type 2 diabetes mellitus

,

diabetes mellitus

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