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Company ReportsMirum Pharmaceuticals

Mirum Pharmaceuticals(MIRM)

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Marketed Drugs

Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Livmarli	Maralixibat	2021-09-29	2031-2040	Pruritus , Alagille syndrome
Cholbam	Cholic acid	2015-03-17		Zellweger syndrome , Inborn errors metabolism

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

neurofibromatosis 1

,

,

hyperlipidemias

,

central nervous system neoplasms

,

neurofibromatoses

,

,

clostridium infections

,

colonic neoplasms

,

rectal neoplasms

,

,

hyperlipoproteinemia type iv

,

metabolic syndrome

,

hypertriglyceridemia

,

familial combined hyperlipidemia

,

liver function tests

,

,

alcoholic hepatitis

,

parkinson disease

,

huntington disease

,

cardiovascular diseases

,

,

,

alcoholic fatty liver

,

,

gastrointestinal diseases

,

digestive system diseases

,

liver neoplasms

,

,

rheumatoid arthritis

,

,

biliary tract diseases

,

barrett esophagus

,

,

cystic fibrosis

,

,

muscle spasticity

,

hereditary spastic paraplegia

,

,

irritable bowel syndrome

,

,

cardiomyopathies

,

disease progression

,

,

neoplasm metastasis

,

radiation injuries

,

,

insulin resistance

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

,

,

x-linked genetic diseases

,

smith-lemli-opitz syndrome

,

,

,

,

bile duct diseases

,

adolescent development

,

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

obstructive jaundice

,

,

esophageal neoplasms

,

head and neck neoplasms

,

end stage liver disease

,

,

,

breast neoplasms

,

,

healthy volunteers/patients

,

intrahepatic cholestasis

,

colorectal neoplasms

,

cerebrotendinous xanthomatosis

,

,

,

pregnancy complications

,

glucose intolerance

,

sclerosing cholangitis

,

peroxisomal disorders

,

zellweger syndrome

,

infantile refsum disease

,

adrenoleukodystrophy

,

,

,

adenomatous polyposis coli

,

nasopharyngeal neoplasms

,

,

retinal detachment

,

dissociative disorders

,

chronic hepatitis c

,

duodenal neoplasms

,

inborn errors metabolism

,

inborn errors lipid metabolism

,

inborn errors steroid metabolism

,

,

follicular lymphoma

,

inborn genetic diseases

,

,

child nutrition disorders

,

ulcerative colitis

,

,

thyroid diseases

,

acute cholecystitis

,

,

acalculous cholecystitis

,

,

,

biliary liver cirrhosis

,

,

,

liver cirrhosis

,

non-alcoholic fatty liver disease

,

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

cholecystolithiasis

,

,

,

,

,

chemical and drug induced liver injury

,

,

gestational diabetes

,

,

autoimmune hepatitis

,

,

,

neonatal hyperbilirubinemia

,

malabsorption syndromes

,

lipid metabolism disorders

,

,

,

hemolytic anemia

,

chronic kidney failure

,

kidney diseases

,

short bowel syndrome

,

cardiac surgical procedures

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

fontan procedure

,

,

communicable diseases

,

,

brain neoplasms

,

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

,

,

,

rhabdomyosarcoma

,

primitive neuroectodermal tumors

,

,

retinal neoplasms

,

neuroectodermal tumors

,

phenylketonurias

,

appetite regulation

,

,

liver transplantation

,

reperfusion injury

,

gastroesophageal reflux

,

,

biliary atresia

,

liver regeneration

,

,

hepatocellular carcinoma

,

cholangiocarcinoma

,

,

hyperbilirubinemia

,

,

glucosephosphate dehydrogenase deficiency

,

hepatic encephalopathy

,

transjugular intrahepatic portasystemic shunt

cerebrotendinous xanthomatosis

,

,

healthy volunteers/patients

,

,

biliary liver cirrhosis

,

substance withdrawal syndrome

,

digestive system diseases

,

biliary tract diseases

,

bile duct diseases

,

intrahepatic cholestasis

,

biliary atresia

,

sclerosing cholangitis

,

alagille syndrome

,

,

,

Maralixibat chloride

,

healthy volunteers/patients

,

,

biliary liver cirrhosis

,

substance withdrawal syndrome

,

digestive system diseases

,

biliary tract diseases

,

bile duct diseases

,

intrahepatic cholestasis

,

biliary atresia

,

sclerosing cholangitis

,

alagille syndrome

,

,

,

healthy volunteers/patients

,

type 2 diabetes mellitus

,

breast neoplasms

,

diabetes mellitus

,

heart valve prosthesis

,

heart valve diseases

,

,

portal hypertension

,

thromboembolism

,

,

venous thromboembolism

,

percutaneous coronary intervention

,

atrial fibrillation

,

diabetic neuropathies

,

cognitive dysfunction

,

chronic obstructive pulmonary disease

,

,

pulmonary emphysema

hodgkin disease

,

mantle-cell lymphoma

,

multiple myeloma

,

prolymphocytic leukemia t-cell

,

plasma cell leukemia

,

,

non-hodgkin lymphoma

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

myeloproliferative disorders

,

primary myelofibrosis

,

b-cell chronic lymphocytic leukemia

,

refractory anemia with excess of blasts

,

myelodysplastic syndromes

,

myelomonocytic leukemia chronic

,

hematologic neoplasms

,

bcr-abl positive chronic myelogenous leukemia

,

burkitt lymphoma

,

,

b-cell lymphoma

,

ovarian neoplasms

,

fallopian tube neoplasms

,

breast neoplasms

,

triple negative breast neoplasms

,

inflammatory breast neoplasms

,

philadelphia chromosome

,

hematologic diseases

,

,

ovarian epithelial carcinoma

,

peritoneal neoplasms

,

,

pancreatic neoplasms

,

myeloid leukemia acute

,

prolymphocytic leukemia

,

b-cell leukemia

,

myelodysplastic-myeloproliferative diseases

,

hematopoietic stem cell transplantation

,

sickle cell anemia

,

graft rejection

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

graft vs host disease

,

,

large b-cell lymphoma diffuse

,

bronchiolitis obliterans syndrome

,

healthy volunteers/patients

,

non-alcoholic fatty liver disease

,

,

alcoholic fatty liver

,

,

,

pregnancy complications

,

intrahepatic cholestasis

,

sclerosing cholangitis

,

biliary liver cirrhosis

,

digestive system diseases

,

prostatic hyperplasia

,

healthy volunteers/patients

,

respiratory tract diseases

,

respiration disorders

,

,

kidney diseases

,

,

,

,

,

respiratory tract infections

,

,

premature obstetric labor

,

,

pulmonary edema

,

,

bacterial infections

,

,

hepatic insufficiency

,

,

non-alcoholic fatty liver disease

,

,

multiple myeloma

,

,

,

breast neoplasms

,

,

,

atherosclerosis

,

obstructive lung diseases

,

plasma cell neoplasms

,

,

pancreatic neoplasms

,

,

follicular lymphoma

,

allergic rhinitis

,

pulmonary tuberculosis

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

sjogren's syndrome

,

,

,

,

,

systemic lupus erythematosus

,

,

,

acquired immunodeficiency syndrome

,

,

type 2 diabetes mellitus

,

human influenza

,

communicable diseases

,

,

,

parkinson disease

,

,

migraine disorders

,

,

major depressive disorder

,

depressive disorder

,

churg-strauss syndrome

,

granulomatosis with polyangiitis

,

systemic vasculitis

,

eosinophilic granuloma

,

neisseria meningitidis

,

haemophilus influenzae type b

,

restless legs syndrome

,

psychomotor agitation

,

,

,

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

urinary tract infections

,

,

respiratory syncytial virus infections

,

,

chronic obstructive pulmonary disease

,

,

diabetes mellitus

,

,

,

,

pulmonary eosinophilia

,

prostatic neoplasms

,

autoimmune diseases

,

,

growth and development

,

,

,

postherpetic neuralgia

,

,

healthy volunteers/patients

,

non-alcoholic fatty liver disease

,

,

alcoholic fatty liver

,

,

,

pregnancy complications

,

intrahepatic cholestasis

,

sclerosing cholangitis

,

biliary liver cirrhosis

,

digestive system diseases

,

Histone-arginine methyltransferase carm1

,

respiratory aspiration

,

thrombocytopenic purpura idiopathic

,

,

photosensitivity disorders

,

renal cell carcinoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

multiple myeloma

,

plasma cell neoplasms

,

healthy volunteers/patients

,

rheumatoid arthritis

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

,

respiratory tract infections

,

,

tendon injuries

,

anxiety disorders

,

,

,

,

,

,

,

,

chronic hepatitis c

,

chronic hepatitis b

,

,

chronic hepatitis

,

,

acquired immunodeficiency syndrome

,

,

inflammatory breast neoplasms

,

atrial fibrillation

,

,

macular degeneration

,

depressive disorder

,

ovarian neoplasms

,

endometrial neoplasms

,

ovarian epithelial carcinoma

,

immunologic deficiency syndromes

,

,

pulmonary tuberculosis

,

,

thrombocytopenia

,

non-small-cell lung carcinoma

,

,

non-hodgkin lymphoma

,

systemic lupus erythematosus

,

,

major depressive disorder

,

,

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

atherosclerosis

,

,

respiratory syncytial viruses

,

,

allergic rhinitis

,

allergic rhinitis perennial

,

breast neoplasms

,

,

diabetes mellitus

,

alzheimer disease

,

,

falciparum malaria

,

postmenopausal osteoporosis

,

prostatic hyperplasia

,

personal satisfaction

,

hypersensitivity

,

dentin sensitivity

,

tension-type headache

,

diabetic neuropathies

,

,

postoperative nausea and vomiting

,

,

,

,

,

,

respiratory sounds

,

allergic rhinitis seasonal

,

,

,

,

,

spinal cord injuries

,

,

erectile dysfunction

,

chronic obstructive pulmonary disease

,

,

,

type 2 diabetes mellitus

,

migraine disorders

,

obstructive lung diseases

,

communicable diseases

,

,

bipolar disorder

,

infectious skin diseases

,

insulin resistance

,

prostatic neoplasms

,

bacterial infections

,

bacterial skin diseases

,

,

,

soft tissue infections

,

,

,

,

healthy volunteers/patients

,

non-hodgkin lymphoma

,

,

b-cell lymphoma

,

metabolic syndrome

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

hematologic neoplasms

,

b-cell chronic lymphocytic leukemia

,

mantle-cell lymphoma

,

,

transitional cell carcinoma

,

ocular hypertension

,

open-angle glaucoma

,

rectal diseases

,

breast neoplasms

,

,

triple negative breast neoplasms

,

kidney transplantation

,

,

renal cell carcinoma

,

kidney neoplasms

,

,

colorectal neoplasms

,

chronic obstructive pulmonary disease

,

respiratory tract infections

,

urologic neoplasms

,

head and neck neoplasms

,

kidney diseases

,

,

pneumococcal infections

,

,

diabetic retinopathy

,

stomach neoplasms

,

lobular carcinoma

,

,

adenocarcinoma of lung

,

,

smoking cessation

,

,

obstructive lung diseases

,

,

diabetic nephropathies

,

ulcerative colitis

,

,

,

alzheimer disease

,

,

urogenital neoplasms

,

urologic diseases

,

neoplasms by site

,

glandular and epithelial neoplasms

,

malignant mesothelioma

,

,

,

pulmonary tuberculosis

,

urinary bladder neoplasms

,

inflammatory bowel diseases

,

intestinal diseases

,

uveal neoplasms

,

macular degeneration

,

,

post-acute covid-19 syndrome

,

,

atopic dermatitis

,

,

,

chronic urticaria

,

,

,

non-small-cell lung carcinoma

,

diabetes mellitus

,

,

type 2 diabetes mellitus

,

human influenza

,

squamous cell carcinoma of head and neck

,

knee osteoarthritis

,

neoplasm metastasis

,

prostatic neoplasms

,

,

glucose metabolism disorders

,

metabolic diseases

,

endocrine system diseases

,

,

ovarian neoplasms

,

,

migraine disorders

,

,

endometrial hyperplasia

,

,

,

,

,

laparoscopic cholecystectomy

,

,

major depressive disorder

,

depressive disorder

,

,

,

bone marrow diseases

,

coronavirus infections

,

,

opioid-induced constipation

,

juvenile arthritis

,

,

,

,

nutrition disorders

,

signs and symptoms

,

nutritional and metabolic diseases

,

signs and symptoms pathological conditions

,

,

rheumatoid arthritis

,

,

,

postoperative pain

,

bipolar disorder

,

,

sprains and strains

,

,

,

,

,

,

premature birth

,

bacterial vaginosis

,

,

h1n1 subtype influenza a virus

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