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Company ReportsMirum Pharmaceuticals

Mirum Pharmaceuticals(MIRM)

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Marketed Drugs

Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Livmarli	Maralixibat	2021-09-29	2031-2040	Pruritus , Alagille syndrome
Cholbam	Cholic acid	2015-03-17		Zellweger syndrome , Inborn errors metabolism

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

neurofibromatosis 1

,

,

hyperlipidemias

,

central nervous system neoplasms

,

neurofibromatoses

,

,

clostridium infections

,

colonic neoplasms

,

rectal neoplasms

,

,

hyperlipoproteinemia type iv

,

metabolic syndrome

,

hypertriglyceridemia

,

familial combined hyperlipidemia

,

liver function tests

,

,

alcoholic hepatitis

,

parkinson disease

,

huntington disease

,

cardiovascular diseases

,

,

,

alcoholic fatty liver

,

,

gastrointestinal diseases

,

digestive system diseases

,

liver neoplasms

,

,

rheumatoid arthritis

,

,

biliary tract diseases

,

barrett esophagus

,

reperfusion injury

,

,

cystic fibrosis

,

,

muscle spasticity

,

hereditary spastic paraplegia

,

,

irritable bowel syndrome

,

,

cardiomyopathies

,

disease progression

,

,

neoplasm metastasis

,

radiation injuries

,

,

insulin resistance

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

,

,

x-linked genetic diseases

,

smith-lemli-opitz syndrome

,

,

,

,

bile duct diseases

,

adolescent development

,

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

obstructive jaundice

,

,

esophageal neoplasms

,

head and neck neoplasms

,

end stage liver disease

,

,

,

breast neoplasms

,

acute kidney injury

,

kidney neoplasms

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

,

healthy volunteers/patients

,

intrahepatic cholestasis

,

colorectal neoplasms

,

cerebrotendinous xanthomatosis

,

,

,

,

pregnancy complications

,

glucose intolerance

,

sclerosing cholangitis

,

peroxisomal disorders

,

zellweger syndrome

,

infantile refsum disease

,

adrenoleukodystrophy

,

,

adenomatous polyposis coli

,

nasopharyngeal neoplasms

,

,

retinal detachment

,

dissociative disorders

,

chronic hepatitis c

,

duodenal neoplasms

,

inborn errors metabolism

,

inborn errors lipid metabolism

,

inborn errors steroid metabolism

,

,

follicular lymphoma

,

inborn genetic diseases

,

,

child nutrition disorders

,

ulcerative colitis

,

,

thyroid diseases

,

acute cholecystitis

,

,

acalculous cholecystitis

,

,

,

biliary liver cirrhosis

,

,

,

liver cirrhosis

,

non-alcoholic fatty liver disease

,

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

cholecystolithiasis

,

,

,

,

,

chemical and drug induced liver injury

,

,

gestational diabetes

,

,

autoimmune hepatitis

,

,

,

neonatal hyperbilirubinemia

,

malabsorption syndromes

,

lipid metabolism disorders

,

,

,

hemolytic anemia

,

chronic kidney failure

,

kidney diseases

,

short bowel syndrome

,

cardiac surgical procedures

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

fontan procedure

,

,

communicable diseases

,

,

brain neoplasms

,

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

,

,

,

rhabdomyosarcoma

,

primitive neuroectodermal tumors

,

,

retinal neoplasms

,

neuroectodermal tumors

,

phenylketonurias

,

appetite regulation

,

,

liver transplantation

,

gastroesophageal reflux

,

,

biliary atresia

,

liver regeneration

,

hepatocellular carcinoma

,

cholangiocarcinoma

,

,

hyperbilirubinemia

,

,

glucosephosphate dehydrogenase deficiency

,

hepatic encephalopathy

,

transjugular intrahepatic portasystemic shunt

,

,

,

healthy volunteers/patients

,

,

biliary liver cirrhosis

,

substance withdrawal syndrome

,

biliary tract diseases

,

bile duct diseases

,

biliary atresia

,

digestive system diseases

,

sclerosing cholangitis

,

cystic fibrosis

,

,

alagille syndrome

,

intrahepatic cholestasis

,

,

,

Maralixibat chloride

,

healthy volunteers/patients

,

,

biliary liver cirrhosis

,

biliary tract diseases

,

bile duct diseases

,

substance withdrawal syndrome

,

digestive system diseases

,

biliary atresia

,

sclerosing cholangitis

,

cystic fibrosis

,

,

alagille syndrome

,

intrahepatic cholestasis

,

,

,

community-acquired infections

,

healthy volunteers/patients

,

non-alcoholic fatty liver disease

,

,

alcoholic fatty liver

,

,

,

pregnancy complications

,

intrahepatic cholestasis

,

sclerosing cholangitis

,

biliary liver cirrhosis

,

digestive system diseases

,

,

,

allergic rhinitis

,

,

allergic conjunctivitis

,

liver neoplasms

,

atopic dermatitis

,

,

neoplasm metastasis

,

healthy volunteers/patients

,

,

prostatic neoplasms

,

,

,

,

esophageal neoplasms

,

postoperative nausea and vomiting

,

soft tissue neoplasms

,

brain neoplasms

,

second primary neoplasms

,

treatment-resistant depressive disorder

,

esophageal squamous cell carcinoma

,

renal cell carcinoma

,

experimental liver cirrhosis

,

chronic obstructive pulmonary disease

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

,

,

colorectal neoplasms

,

pancreatic ductal carcinoma

,

biliary tract neoplasms

,

non-muscle invasive bladder neoplasms

,

non-small-cell lung carcinoma

,

,

,

,

ovarian neoplasms

,

uterine cervical neoplasms

,

triple negative breast neoplasms

,

breast neoplasms

,

condylomata acuminata

,

hepatocellular carcinoma

,

,

immunologic deficiency syndromes

,

,

antibiotic prophylaxis

,

,

chronic hepatitis b

,

ovarian epithelial carcinoma

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

,

cystic fibrosis

,

pulmonary hypertension

,

pulmonary arterial hypertension

,

endometrial neoplasms

,

fallopian tube neoplasms

,

urinary bladder neoplasms

,

acquired immunodeficiency syndrome

,

,

chronic hepatitis c

,

,

,

,

,

neuromuscular blockade

,

hematologic neoplasms

,

hematopoietic stem cell transplantation

,

,

pseudomonas infections

,

pseudomonas aeruginosa

,

gram-negative bacterial infections

,

,

chronic kidney failure

,

kidney diseases

,

chronic hepatitis

,

intestinal diseases

,

,

non-hodgkin lymphoma

,

,

,

traumatic brain injuries

,

brain concussion

,

,

post-concussion syndrome

,

papillomavirus infections

,

uterine cervical dysplasia

,

healthy volunteers/patients

,

non-alcoholic fatty liver disease

,

,

alcoholic fatty liver

,

,

,

pregnancy complications

,

intrahepatic cholestasis

,

sclerosing cholangitis

,

biliary liver cirrhosis

,

digestive system diseases

,

Histone-arginine methyltransferase carm1

multiple myeloma

,

myeloid leukemia

,

hypercholesterolemia

,

atherosclerosis

,

plasma cell neoplasms

,

gastrointestinal neoplasms

,

intestinal neoplasms

,

,

b-cell lymphoma

,

hematologic neoplasms

,

non-hodgkin lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

hodgkin disease

,

,

alzheimer disease

,

myeloid leukemia acute

,

b-cell chronic lymphocytic leukemia

,

follicular lymphoma

,

large b-cell lymphoma diffuse

,

b-cell leukemia

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

healthy volunteers/patients

,

,

,

colorectal neoplasms

,

chronic hepatitis

,

,

,

pancreatic neoplasms

,

squamous cell carcinoma of head and neck

,

myeloid leukemia chronic-phase

,

bronchiolitis obliterans syndrome

,

,

hepatitis b virus

,

,

ovarian neoplasms

,

fallopian tube neoplasms

,

clear cell adenocarcinoma

,

uveal neoplasms

,

cutaneous malignant melanoma

,

,

diabetic neuropathies

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

,

depressive disorder

,

,

postherpetic neuralgia

,

interstitial lung diseases

,

common variable immunodeficiency

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

rectal neoplasms

,

urinary bladder neoplasms

,

head and neck neoplasms

,

squamous cell carcinoma

,

pancreatic ductal carcinoma

,

brain neoplasms

,

,

triple negative breast neoplasms

,

,

,

,

prostatic neoplasms

,

non-small-cell lung carcinoma

,

breast neoplasms

,

chronic hepatitis c

,

diabetes mellitus

,

small cell lung carcinoma

,

renal cell carcinoma

,

systemic lupus erythematosus

,

,

,

neoplasm metastasis

,

,

connective tissue diseases

,

immune system diseases

,

autoimmune diseases

,

venous thrombosis

,

pulmonary embolism

,

,

developmental disabilities

,

autism spectrum disorder

,

pervasive child development disorders

,

,

,

type 2 diabetes mellitus

,

rheumatoid arthritis

,

,

,

chronic hepatitis b

,

atrial fibrillation

,

communicable diseases

,

,

systemic scleroderma

,

juvenile arthritis

,

psoriatic arthritis

,

ankylosing spondylitis

,

sjogren's syndrome

,

undifferentiated connective tissue diseases

,

,

,

mixed connective tissue disease

healthy volunteers/patients

,

,

pharmacokinetics

,

,

,

ocular hypertension

,

open-angle glaucoma

,

multiple myeloma

,

plasma cell neoplasms

,

erectile dysfunction

,

gastrointestinal neoplasms

,

renal cell carcinoma

,

,

breast neoplasms

,

triple negative breast neoplasms

,

,

prostatic neoplasms

,

,

,

squamous cell carcinoma of head and neck

,

ovarian neoplasms

,

pancreatic neoplasms

,

,

squamous cell carcinoma

,

,

castration-resistant prostatic neoplasms

,

chronic hepatitis

,

colorectal neoplasms

,

stomach neoplasms

,

,

biliary tract neoplasms

,

,

uterine cervical neoplasms

,

,

large b-cell lymphoma diffuse

,

transitional cell carcinoma

,

,

gastrointestinal diseases

,

,

rna virus infections

,

digestive system diseases

,

viral hepatitis human

,

flaviviridae infections

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

obstructive sleep apnea

,

sleep apnea syndromes

,

,

,

disorders of excessive somnolence

,

,

papillomavirus infections

,

vaginal neoplasms

,

vulvar neoplasms

,

condylomata acuminata

,

migraine disorders

,

endometrial neoplasms

,

esophageal neoplasms

,

uterine neoplasms

,

,

mullerian mixed tumor

,

esophageal squamous cell carcinoma

,

b-cell lymphoma

,

head and neck neoplasms

,

malignant mesothelioma

,

,

x-linked bulbo-spinal atrophy

,

prostatic hyperplasia

,

,

muscular atrophy

,

,

,

urologic neoplasms

,

hepatocellular carcinoma

,

urinary bladder neoplasms

,

liver neoplasms

,

microsatellite instability

,

hidradenitis suppurativa

,

merkel cell carcinoma

,

non-hodgkin lymphoma

,

follicular lymphoma

,

non-small-cell lung carcinoma

,

type 2 diabetes mellitus

,

diabetes mellitus

,

chronic hepatitis c

,

,

,

,

small cell lung carcinoma

,

,

neoplasm metastasis

,

,

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

,

,

polycystic kidney diseases

,

,

postherpetic neuralgia

,

,

,

,

,

,

,

communicable diseases

,

acquired immunodeficiency syndrome

,

,

,

,

,

,

kidney diseases

,

hepatitis a virus

,

,

chronic renal insufficiency

,

chronic disease

,

drug-related side effects and adverse reactions

,

prostatic neoplasms

,

,

small cell carcinoma

,

neuroendocrine carcinoma

,

urinary bladder neoplasms

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