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Esperion Therapeutics
Esperion Therapeutics
(ESPR)
Esperion Therapeutics, Inc. is a public American pharmaceutical company focused on the development of bempedoic acid, an orally available small molecule designed to lower elevated levels of LDL-C. The company is headquartered in Ann Arbor, Michigan.
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Therapeutic Areas:
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Nexletol
Bempedoic acid
2020-02-21
2025-2040
Hypercholesterolemia
,
Dyslipidemias
,
Atherosclerosis
,
Hyperlipoproteinemia type ii
,
Familial combined hyperlipidemia
Nexlizet
Bempedoic acid
,
Ezetimibe
2020-02-26
2025-2040
Hypercholesterolemia
,
Dyslipidemias
,
Atherosclerosis
,
Hyperlipoproteinemia type ii
,
Familial combined hyperlipidemia
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Bempedoic acid
type 2 diabetes mellitus
,
diabetes mellitus
,
dyslipidemias
,
hypertension
,
hypertriglyceridemia
,
hypercholesterolemia
,
hyperlipidemias
,
atherosclerosis
,
hyperlipoproteinemias
,
drug-related side effects and adverse reactions
,
cardiovascular diseases
,
acute coronary syndrome
,
st elevation myocardial infarction
,
non-st elevated myocardial infarction
,
pregnancy
Ezetimibe
hyperlipoproteinemia type ii
,
hyperlipidemias
,
hyperlipoproteinemias
,
diabetes mellitus
,
type 2 diabetes mellitus
,
familial combined hyperlipidemia
,
inborn errors metabolism
,
inborn errors lipid metabolism
,
homozygous familial hypercholesterolemia
,
hypertriglyceridemia
,
syndrome
,
myocardial infarction
,
acute coronary syndrome
,
infarction
,
aortic valve stenosis
,
pathologic constriction
,
vascular diseases
,
carotid artery diseases
,
hypercholesterolemia
,
coronary disease
,
heart diseases
,
coronary artery disease
,
myocardial ischemia
,
atherosclerosis
,
dyslipidemias
,
cardiovascular diseases
,
metabolic syndrome
,
metabolic diseases
,
lipid metabolism disorders
,
arteriosclerosis
,
neoplasms
Serine
healthy volunteers/patients
,
liver diseases
,
hepatic insufficiency
,
renal insufficiency
,
coronary disease
,
balloon angioplasty coronary
,
emphysema
,
alpha 1-antitrypsin deficiency
,
pulmonary emphysema
,
thrombosis
,
venous thrombosis
,
thromboembolism
,
pulmonary embolism
,
embolism
,
homozygous familial hypercholesterolemia
,
atrial fibrillation
,
hemophilia a
,
unstable angina
,
sepsis
,
septic shock
,
shock
,
cardiovascular diseases
,
atherosclerosis
,
hypercholesterolemia
,
hyperlipoproteinemia type ii
,
acute coronary syndrome
,
myocardial infarction
,
infarction
,
coronary artery disease
,
myocardial ischemia
,
syndrome
,
atherosclerotic plaque
,
dyslipidemias
Mevalotin
healthy volunteers/patients
,
rheumatoid arthritis
,
arthritis
,
acute kidney injury
,
drug interactions
,
therapeutic equivalency
,
hiv seronegativity
,
nephrotic syndrome
,
nephrosis
,
hepatitis c
,
biotransformation
,
pharmacokinetics
,
peripheral arterial disease
,
ventilator-associated pneumonia
,
pneumonia
,
wounds and injuries
,
hematopoietic stem cell transplantation
,
fontan procedure
,
univentricular heart
,
leukemia
,
fibrosis
,
progeria
,
neoplasms
,
myeloid leukemia acute
,
megakaryoblastic leukemia acute
,
monocytic leukemia acute
,
myelomonocytic leukemia acute
,
myeloid leukemia
,
erythroblastic leukemia acute
,
tuberculosis
,
eclampsia
,
metabolic diseases
,
pulmonary fibrosis
,
hermanski-pudlak syndrome
,
oculocutaneous albinism
,
platelet storage pool deficiency
,
albinism
,
colorectal neoplasms
,
melanoma
,
uveal neoplasms
,
systemic lupus erythematosus
,
hematologic neoplasms
,
sarcoma
,
lymphoma
,
cardiomyopathies
,
pulmonary tuberculosis
,
liver cirrhosis
,
mucocutaneous lymph node syndrome
,
ototoxicity
,
lymphedema
,
metabolic syndrome
,
atherosclerosis
,
hyperlipoproteinemia type ii
,
breast neoplasms
,
ischemic stroke
,
hepatocellular carcinoma
,
liver neoplasms
,
pre-eclampsia
,
carcinoma
,
chronic kidney failure
,
vascular diseases
,
arthrogryposis
,
left ventricular hypertrophy
,
hypertrophy
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
sclerosis
,
homozygous familial hypercholesterolemia
,
familial combined hyperlipidemia
,
lung neoplasms
,
small cell lung carcinoma
,
hyperlipoproteinemia type iii
,
arterial occlusive diseases
,
albuminuria
,
retinal diseases
,
pregnancy-induced hypertension
,
obstetric labor complications
,
disease progression
,
vascular dementia
,
cognitive dysfunction
,
hypercholesterolemia
,
dyslipidemias
,
hiv infections
,
cardiovascular diseases
,
hyperlipidemias
,
coronary artery disease
,
diabetes mellitus
,
hyperlipoproteinemias
,
coronary disease
,
myocardial ischemia
,
hypertension
,
syndrome
,
heart diseases
,
acute coronary syndrome
,
stroke
,
type 2 diabetes mellitus
,
stable angina
,
myocardial infarction
,
infarction
,
hypertriglyceridemia
,
kidney diseases
,
schizophrenia
,
angina pectoris
,
lipodystrophy
,
heart failure
,
drug-related side effects and adverse reactions
,
polycystic kidney diseases
,
autosomal dominant polycystic kidney
,
inflammation
,
recurrence
,
chronic renal insufficiency
,
psychotic disorders
,
infections
,
liver diseases
,
drug-eluting stents
,
osteoporosis
,
postmenopausal osteoporosis
,
acute-phase reaction
,
hiv
,
prediabetic state
,
hyperglycemia
,
alzheimer disease
,
aging
,
glucose metabolism disorders
,
lipid metabolism
,
stomach neoplasms
,
esophageal neoplasms
,
inferior wall myocardial infarction
,
arteriosclerosis
,
transient ischemic attack
,
st elevation myocardial infarction
,
unstable angina
,
malignant hyperthermia
,
prostatic neoplasms
,
postpartum depression
,
myelodysplastic syndromes
,
myeloproliferative disorders
,
myelomonocytic leukemia chronic
,
anemia
,
myelodysplastic-myeloproliferative diseases
,
myelomonocytic leukemia juvenile
,
preleukemia
,
refractory anemia with excess of blasts
,
refractory anemia
,
carotid artery diseases
,
pain
,
endometriosis
,
acquired immunodeficiency syndrome
,
crohn disease
,
proteinuria
,
muscular diseases
Evidence
fibrosis
,
idiopathic pulmonary fibrosis
,
pulmonary fibrosis
,
glioblastoma
,
gliosarcoma
,
rheumatoid arthritis
,
arthritis
,
glioma
,
esophageal neoplasms
,
geographic atrophy
,
atrophy
,
choroidal neovascularization
,
non-hodgkin lymphoma
,
lymphoma
,
follicular lymphoma
,
thyroid neoplasms
,
thyroid diseases
,
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
carcinoma
,
squamous cell carcinoma
,
ovarian neoplasms
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
lung neoplasms
,
non-small-cell lung carcinoma
,
breast neoplasms
,
macular degeneration
,
neoplasm metastasis
,
ischemic stroke
,
stroke
,
ischemia
,
cerebral infarction
,
leukemia
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
disease progression
,
glaucoma
,
open-angle glaucoma
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