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Company ReportsAkebia Therapeutics

Akebia Therapeutics(AKBA)

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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Vafseo	Vadadustat	2023-04-24		Chronic renal insufficiency , Anemia

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

drug interactions

,

,

hepatic insufficiency

,

pharmacokinetics

,

chronic kidney failure

,

,

kidney diseases

,

chronic renal insufficiency

,

,

,

enterovirus infections

Calcium carbonate

metabolic bone diseases

,

Sodium chloride

healthy volunteers/patients

,

,

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

,

,

pulmonary eosinophilia

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

migraine disorders

,

sleep wake disorders

therapeutic equivalency

,

,

,

biological availability

,

,

,

non-hodgkin lymphoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

retinal detachment

,

vascular diseases

,

macular degeneration

,

wet macular degeneration

,

polypoidal choroidal vasculopathy

,

alzheimer disease

,

,

borrelia infections

,

rheumatoid arthritis

,

,

,

,

small cell lung carcinoma

,

streptococcal infections

,

prostatic neoplasms

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

renal cell carcinoma

,

,

hepatocellular carcinoma

,

,

liver neoplasms

,

gastrointestinal stromal tumors

,

,

multiple sclerosis

,

,

,

multiple organ failure

,

,

facial paralysis

,

,

premature birth

,

bacterial vaginosis

,

vaginal diseases

,

,

venous thromboembolism

,

,

venous thrombosis

,

pulmonary embolism

,

,

intracranial thrombosis

,

thromboembolism

,

intracranial sinus thrombosis

,

,

,

contact dermatitis

,

bacterial skin diseases

,

,

,

asymptomatic infections

,

,

escherichia coli infections

,

gastroenteritis

,

pharmacokinetics

,

,

hydrogen-ion concentration

,

,

healthy volunteers/patients

,

,

sjogren's syndrome

,

,

,

,

,

pyruvate dehydrogenase complex deficiency disease

,

,

,

child nutrition disorders

,

,

,

type 2 diabetes mellitus

,

,

diabetes mellitus

,

glucose intolerance

,

,

insulin resistance

,

metabolic syndrome

,

,

feeding behavior

,

glucose metabolism disorders

,

metabolic diseases

,

abdominal obesity

,

,

,

prediabetic state

,

glucose tolerance test

,

,

,

type 1 diabetes mellitus

,

,

,

,

congenital hyperinsulinism

,

nesidioblastosis

,

driving under the influence

,

glycogen storage disease type iii

,

glycogen storage disease

,

kidney transplantation

,

,

sleep deprivation

,

cardiovascular diseases

,

,

hypersensitivity

,

gastrointestinal microbiome

,

chronic disease

,

,

,

adolescent development

,

,

appetitive behavior

,

,

chronic periodontitis

,

,

,

,

atherosclerosis

,

,

intestinal absorption

,

,

,

blood glucose self-monitoring

,

deglutition disorders

,

,

,

,

platelet aggregation

,

wounds and injuries

,

spinal cord injuries

,

cold temperature

,

,

,

vascular stiffness

,

,

exercise tolerance

,

alcohol drinking

healthy volunteers/patients

,

chronic kidney failure

,

kidney diseases

,

healthy volunteers/patients

healthy volunteers/patients

,

type 2 diabetes mellitus

,

,

diabetes mellitus

,

,

diabetic nephropathies

,

kidney diseases

,

Microcrystalline cellulose

,

therapeutic equivalency

,

,

,

,

hematologic neoplasms

,

non-hodgkin lymphoma

,

,

hodgkin disease

,

,

lupus nephritis

,

systemic lupus erythematosus

,

,

multiple sclerosis

,

healthy volunteers/patients

,

,

,

atrophic vaginitis

healthy volunteers/patients

,

rheumatoid arthritis

,

,

acute kidney injury

,

drug interactions

,

therapeutic equivalency

,

hiv seronegativity

,

nephrotic syndrome

,

,

,

biotransformation

,

pharmacokinetics

,

peripheral arterial disease

,

ventilator-associated pneumonia

,

,

wounds and injuries

,

hematopoietic stem cell transplantation

,

fontan procedure

,

univentricular heart

,

,

,

,

,

myeloid leukemia acute

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

myeloid leukemia

,

erythroblastic leukemia acute

,

,

,

metabolic diseases

,

pulmonary fibrosis

,

hermanski-pudlak syndrome

,

oculocutaneous albinism

,

platelet storage pool deficiency

,

,

colorectal neoplasms

,

,

uveal neoplasms

,

systemic lupus erythematosus

,

hematologic neoplasms

,

,

,

cardiomyopathies

,

pulmonary tuberculosis

,

liver cirrhosis

,

mucocutaneous lymph node syndrome

,

,

,

metabolic syndrome

,

atherosclerosis

,

hyperlipoproteinemia type ii

,

breast neoplasms

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

chronic kidney failure

,

vascular diseases

,

,

left ventricular hypertrophy

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

homozygous familial hypercholesterolemia

,

familial combined hyperlipidemia

,

,

small cell lung carcinoma

,

hyperlipoproteinemia type iii

,

arterial occlusive diseases

,

,

retinal diseases

,

pregnancy-induced hypertension

,

obstetric labor complications

,

disease progression

,

vascular dementia

,

cognitive dysfunction

,

hypercholesterolemia

,

,

,

cardiovascular diseases

,

hyperlipidemias

,

coronary artery disease

,

diabetes mellitus

,

hyperlipoproteinemias

,

coronary disease

,

myocardial ischemia

,

,

,

,

,

acute coronary syndrome

,

ischemic stroke

,

type 2 diabetes mellitus

,

,

myocardial infarction

,

,

hypertriglyceridemia

,

kidney diseases

,

,

angina pectoris

,

,

,

drug-related side effects and adverse reactions

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

transient ischemic attack

,

,

,

chronic renal insufficiency

,

psychotic disorders

,

,

,

,

cerebral infarction

,

drug-eluting stents

,

,

postmenopausal osteoporosis

,

acute-phase reaction

,

,

prediabetic state

,

,

alzheimer disease

,

,

glucose metabolism disorders

,

lipid metabolism

,

stomach neoplasms

,

esophageal neoplasms

,

inferior wall myocardial infarction

,

arteriosclerosis

,

st elevation myocardial infarction

,

unstable angina

,

malignant hyperthermia

,

prostatic neoplasms

,

postpartum depression

,

myelodysplastic syndromes

,

myeloproliferative disorders

,

myelomonocytic leukemia chronic

,

,

myelodysplastic-myeloproliferative diseases

,

myelomonocytic leukemia juvenile

,

,

refractory anemia with excess of blasts

,

refractory anemia

,

carotid artery diseases

,

,

,

acquired immunodeficiency syndrome

,

,

,

muscular diseases

,

healthy volunteers/patients

,

gastrointestinal diseases

,

digestive system diseases

therapeutic equivalency

,

pharmacokinetics

,

,

communicable diseases

,

,

alzheimer disease

,

,

juvenile arthritis

,

,

,

chronic pancreatitis

,

exercise-induced asthma

,

breast neoplasms

,

hematologic neoplasms

,

,

,

gastrointestinal diseases

,

,

,

,

peptic ulcer hemorrhage

,

rheumatoid arthritis

,

,

,

gastrointestinal hemorrhage

,

digestive system diseases

,

digestive signs and symptoms

,

simian acquired immunodeficiency syndrome

,

eosinophilic esophagitis

,

esophageal neoplasms

,

precancerous conditions

,

,

,

,

zollinger-ellison syndrome

,

,

postpartum hemorrhage

,

gastroesophageal reflux

,

peptic esophagitis

,

,

healthy volunteers/patients

,

,

,

,

barrett esophagus

,

non-erosive reflux disease

,

laryngopharyngeal reflux

,

,

,

,

,

atrophic gastritis

,

,

,

,

bariatric surgery

,

critical illness

,

,

,

pathologic constriction

,

,

,

microscopic colitis

,

,

metabolic diseases

,

calcium metabolism disorders

,

,

,

vasomotor rhinitis

pharmacokinetics

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

positron-emission tomography

,

,

alzheimer disease

,

diagnostic imaging

,

medical sociology

,

,

,

drug interactions

,

electrocardiography

,

therapeutic equivalency

,

pharmacological phenomena

,

,

,

stomach neoplasms

,

hypophosphatemia

,

hematologic neoplasms

,

respiratory aspiration

,

cystic fibrosis

,

pseudomonas infections

,

biological availability

,

castration-resistant prostatic neoplasms

,

,

non-small-cell lung carcinoma

,

,

breast neoplasms

,

postcoital contraception

,

ovulation inhibition

,

atrial fibrillation

,

,

parkinson disease

,

small cell lung carcinoma

,

ovarian neoplasms

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

,

cardiomyopathies

,

,

,

,

overactive urinary bladder

,

hormonal contraception

,

unplanned pregnancy

,

b-cell lymphoma

,

,

skin abnormalities

,

myocardial infarction

,

,

,

acquired immunodeficiency syndrome

,

magnetic resonance angiography

,

,

left ventricular dysfunction

,

ventricular dysfunction

,

interstitial lung diseases

,

ovarian epithelial carcinoma

,

thyroid neoplasms

,

thyroid diseases

,

pancreatic neoplasms

,

,

,

,

,

prostatic hyperplasia

,

,

angina pectoris

,

,

ischemic stroke

,

,

cerebral infarction

,

urologic neoplasms

,

head and neck neoplasms

,

thromboembolism

,

venous thromboembolism

,

pulmonary hypertension

,

,

hyperphosphatemia

,

,

prostatic neoplasms

,

,

venous thrombosis

,

non-hodgkin lymphoma

,

,

chronic renal insufficiency

,

kidney diseases

,

surgical blood loss

,

,

,

vascular diseases

,

peripheral arterial disease

,

peripheral vascular diseases

,

postoperative hemorrhage

,

pulmonary embolism

,

,

cardiovascular diseases

,

,

,

spinal cord injuries

,

pathologic constriction

,

renal artery obstruction

,

,

bacterial infections

,

esophageal neoplasms

,

,

,

intraabdominal infections

,

,

chronic progressive multiple sclerosis

,

blood coagulation disorders

,

hemostatic disorders

,

hormone replacement therapy

,

hyperlipidemias

,

hyperlipoproteinemias

,

choroidal neovascularization

,

,

degenerative myopia

,

pathologic neovascularization

,

,

aspiration pneumonia

,

,

,

pelvic infection

,

pelvic inflammatory disease

,

,

metabolic bone diseases

,

,

premenstrual dysphoric disorder

,

diabetic nephropathies

,

,

follicular lymphoma

,

wounds and injuries

,

brain neoplasms

,

congenital abnormalities

,

cardiovascular abnormalities

,

,

memory disorders

,

carotid stenosis

,

pulmonary arterial hypertension

,

,

,

depressive disorder

,

hypersensitivity

,

aortic valve stenosis

,

heart valve diseases

,

ventricular outflow obstruction

,

abdominal abscess

,

erectile dysfunction

,

,

,

,

,

,

,

healthy volunteers/patients

,

renal cell carcinoma

,

communicable diseases

,

multiple sclerosis

,

,

,

,

essential hypertension

,

atopic dermatitis

,

,

liver neoplasms

,

,

relapsing-remitting multiple sclerosis

,

,

hepatocellular carcinoma

,

urinary tract infections

,

diabetes mellitus

,

coronary artery disease

,

,

type 2 diabetes mellitus

,

colorectal neoplasms

,

,

,

,

physiological sexual dysfunction

,

magnetic resonance imaging

,

neoplasm metastasis

,

coronary disease

,

acute coronary syndrome

,

myocardial ischemia

,

,

tension-type headache

,

,

,

renal insufficiency

,

chronic bronchitis

,

,

,

,

,

respiratory tract infections

,

,

peripheral nervous system diseases

,

ischemic optic neuropathy

,

optic nerve diseases

,

,

,

macular degeneration

,

energy metabolism

,

,

maxillary sinusitis

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

medicated intrauterine devices

,

,

gene expression

,

cell proliferation

,

,

central nervous system neoplasms

,

photoallergic dermatitis

,

phototoxic dermatitis

,

four-dimensional computed tomography

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