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Disease Reports

Company ReportsACTUATE THERAPEUTICS, INC.

ACTUATE THERAPEUTICS, INC.

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Therapeutic Areas:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

drug interactions

,

,

,

,

pure autonomic failure

,

arteriovenous fistula

,

,

,

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

hematologic neoplasms

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

myeloproliferative disorders

,

non-hodgkin lymphoma

,

primary myelofibrosis

,

multiple myeloma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia chronic

,

,

hodgkin disease

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelodysplastic-myeloproliferative diseases

,

plasma cell neoplasms

,

myeloid leukemia chronic-phase

,

myeloid leukemia

,

neoplasm metastasis

,

myeloid leukemia accelerated phase

,

myelomonocytic leukemia juvenile

,

,

,

,

lymphoid leukemia

,

,

,

shy-drager syndrome

,

multiple system atrophy

,

postural orthostatic tachycardia syndrome

,

,

pharmacokinetics

,

peripheral arterial disease

,

peripheral vascular diseases

,

acute intermittent porphyria

,

hereditary coproporphyria

,

erythropoietic porphyria

,

,

hepatic porphyrias

,

,

pancreatic ductal carcinoma

,

endomyocardial fibrosis

,

sex characteristics

,

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

social cognition

,

,

pancreatic neoplasms

,

cardiomyopathies

,

,

,

,

sickle cell anemia

,

breast neoplasms

,

,

cystic fibrosis

,

post-traumatic stress disorders

,

hypertrophic cardiomyopathy

,

radiation fibrosis syndrome

,

respiratory distress syndrome

,

acute lung injury

,

newborn respiratory distress syndrome

,

,

eosinophilic esophagitis

,

,

traumatic stress disorders

,

radiation pneumonitis

,

prediabetic state

,

knee osteoarthritis

,

,

hip osteoarthritis

,

brain neoplasms

,

mucopolysaccharidosis iv

,

mucopolysaccharidosis vi

,

mucopolysaccharidoses

,

mucopolysaccharidosis i

,

osteochondrodysplasias

,

intracranial hypertension

,

sedentary behavior

,

pulmonary vein stenosis

,

,

,

right ventricular dysfunction

,

congenital abnormalities

,

congenital heart defects

,

tetralogy of fallot

,

,

acquired immunodeficiency syndrome

,

connective tissue diseases

,

obstructive sleep apnea

,

,

kidney transplantation

,

focal segmental glomerulosclerosis

,

hermanski-pudlak syndrome

,

oculocutaneous albinism

,

platelet storage pool deficiency

,

,

type 1 diabetes mellitus

,

acoustic neuroma

,

,

,

endocardial fibroelastosis

,

femoracetabular impingement

,

,

colorectal neoplasms

,

gastrointestinal neoplasms

,

,

,

,

,

oxidative stress

,

replacement arthroplasty knee

,

peripheral nervous system diseases

,

,

marfan syndrome

,

,

,

non-alcoholic fatty liver disease

,

pulmonary fibrosis

,

hyperlipidemias

,

,

acute kidney injury

,

,

cognitive dysfunction

,

ventricular dysfunction

,

,

pathologic dilatation

,

idiopathic pulmonary fibrosis

,

metabolic diseases

,

cerebral small vessel diseases

,

alzheimer disease

,

hyperlipoproteinemias

,

metabolic brain diseases

,

pulmonary hypertension

,

retinal diseases

,

,

primary hyperoxaluria

,

left ventricular dysfunction

,

ventricular remodeling

,

microvascular angina

,

vascular remodeling

,

exercise tolerance

,

aortic coarctation

,

,

kidney diseases

,

essential hypertension

,

diabetic nephropathies

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

chronic renal insufficiency

,

,

,

,

cardiovascular diseases

,

,

,

renal insufficiency

,

,

iga glomerulonephritis

,

left ventricular hypertrophy

,

insulin resistance

,

glomerulonephritis

,

,

coronavirus infections

,

,

metabolic syndrome

,

communicable diseases

,

,

,

severe acute respiratory syndrome

,

chronic kidney failure

,

atherosclerosis

,

,

coronary artery disease

,

atrial fibrillation

,

drug-related side effects and adverse reactions

,

wounds and injuries

,

,

,

sleep apnea syndromes

,

glucose intolerance

,

,

myocardial ischemia

,

aortic valve insufficiency

,

,

pathologic constriction

,

,

pulmonary emphysema

,

chronic obstructive pulmonary disease

,

chronic bronchitis

,

,

,

,

ischemic stroke

,

prehypertension

,

liver cirrhosis

,

respiratory tract diseases

,

respiration disorders

,

peritoneal dialysis

,

aortic valve stenosis

,

,

respiratory aspiration

,

sleep wake disorders

,

pharmacogenomic testing

,

ulcerative colitis

,

,

,

,

,

,

psychotic disorders

,

bipolar disorder

,

major depressive disorder

,

mental disorders

,

depressive disorder

,

low cardiac output

,

graft rejection

,

nephrolithiasis

,

,

,

continuous ambulatory peritoneal dialysis

,

systolic murmurs

,

isolated systolic hypertension

,

carotid stenosis

,

cerebral infarction

,

,

,

,

chronic hepatitis c

,

,

chronic hepatitis

,

,

liver transplantation

,

alcoholic liver cirrhosis

,

,

hyperaldosteronism

,

rectal diseases

,

coronary disease

,

heart disease risk factors

,

masked hypertension

,

diabetic neuropathies

,

athletic injuries

,

,

,

systolic heart failure

,

,

urologic diseases

,

systemic scleroderma

,

localized scleroderma

,

diffuse scleroderma

,

,

,

lupus nephritis

,

rheumatoid arthritis

,

,

duchenne muscular dystrophy

,

muscular dystrophies

,

membranous glomerulonephritis

,

,

bicuspid aortic valve disease

,

thoracic aortic aneurysm

,

heart valve diseases

,

aortic aneurysm

,

long-term memory

,

short-term memory

,

non-small-cell lung carcinoma

,

,

precancerous conditions

,

sick sinus syndrome

,

glucose metabolism disorders

,

,

hypersensitivity

,

disease progression

,

drug dose-response relationship

,

bariatric surgery

,

metabolic bone diseases

,

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

vascular stiffness

,

,

healthy volunteers/patients

,

essential hypertension

,

type 1 diabetes mellitus

,

type 2 diabetes mellitus

,

,

chronic hepatitis

,

liver cirrhosis

,

,

,

castration-resistant prostatic neoplasms

,

non-small-cell lung carcinoma

,

,

alzheimer disease

,

,

thyroid neoplasms

,

thyroid diseases

,

diabetes mellitus

,

,

,

chronic hepatitis c

,

,

,

acquired immunodeficiency syndrome

,

,

immunologic deficiency syndromes

,

small cell lung carcinoma

,

,

coronary artery disease

,

myocardial ischemia

,

,

atherosclerosis

,

rheumatoid arthritis

,

,

neuromuscular blockade

,

prostatic neoplasms

,

,

acute coronary syndrome

,

chronic renal insufficiency

,

kidney diseases

,

,

,

,

uterine prolapse

,

intestinal obstruction

,

,

spinal diseases

,

delayed emergence from anesthesia

,

,

,

muscle relaxation

,

,

,

,

,

urinary retention

,

,

female infertility

,

uterine diseases

,

postoperative complications

,

,

wound infection

,

surgical wound infection

colorectal neoplasms

,

squamous cell neoplasms

,

,

head and neck neoplasms

,

pancreatic ductal carcinoma

,

triple negative breast neoplasms

,

,

merkel cell carcinoma

,

mycosis fungoides

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

gastrointestinal stromal tumors

,

neoplasm metastasis

,

pancreatic neoplasms

,

endometrial neoplasms

,

stomach neoplasms

,

esophageal neoplasms

,

bile duct neoplasms

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

renal cell carcinoma

,

ovarian neoplasms

,

urologic neoplasms

,

,

breast neoplasms

,

,

fallopian tube neoplasms

,

ovarian epithelial carcinoma

,

peritoneal neoplasms

,

transitional cell carcinoma

,

neoadjuvant therapy

,

kidney diseases

,

urogenital neoplasms

,

kidney neoplasms

,

urologic diseases

,

neoplasms by site

,

glandular and epithelial neoplasms

,

non-small-cell lung carcinoma

,

,

squamous cell carcinoma of head and neck

,

urinary bladder neoplasms

,

squamous cell carcinoma

,

non-muscle invasive bladder neoplasms

,

disease progression

alzheimer disease

,

myelodysplastic syndromes

,

,

hepatic insufficiency

,

cognitive dysfunction

,

precursor cell lymphoblastic leukemia-lymphoma

,

maximum tolerated dose

,

antineoplastic protocols

,

pharmacokinetics

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

,

aplastic anemia

,

paraproteinemias

,

monoclonal gammopathy of undetermined significance

,

,

laboratory infection

,

myeloid leukemia acute

,

castration-resistant prostatic neoplasms

,

myeloid leukemia

,

,

,

acquired immunodeficiency syndrome

,

hematologic neoplasms

,

,

immunologic deficiency syndromes

,

,

hypergammaglobulinemia

,

,

chronic hepatitis b

,

,

,

prostatic neoplasms

,

neoplasm metastasis

,

multiple myeloma

,

plasma cell neoplasms

,

colorectal neoplasms

,

colonic neoplasms

,

colonic diseases

,

,

sexually transmitted diseases

,

retroviridae infections

,

viral sexually transmitted diseases

,

b-cell lymphoma marginal zone

,

burkitt lymphoma

,

,

pulmonary tuberculosis

,

healthy volunteers/patients

,

non-small-cell lung carcinoma

,

b-cell lymphoma

,

large b-cell lymphoma diffuse

,

non-hodgkin lymphoma

,

follicular lymphoma

,

,

graft vs host disease

,

bronchiolitis obliterans syndrome

,

renal insufficiency

,

respiratory syncytial viruses

,

,

ebola hemorrhagic fever

,

cerebrospinal fluid leak

,

,

soft tissue injuries

,

respiratory tract diseases

,

kidney transplantation

,

prolymphocytic leukemia t-cell

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

atrial fibrillation

Polyglycolic acid

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

,

invasive candidiasis

,

,

,

,

,

invasive fungal infections

,

communicable diseases

,

pneumocystis pneumonia

,

,

,

invasive hydatidiform mole

Globulin, immune

thoracic neoplasms

,

,

small cell carcinoma

,

b-cell lymphoma marginal zone

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

,

respiratory tract neoplasms

,

bronchogenic carcinoma

,

endocrine gland neoplasms

,

glandular and epithelial neoplasms

,

breast diseases

,

bronchial neoplasms

,

,

colorectal neoplasms

,

pancreatic neoplasms

,

,

renal cell carcinoma

,

ovarian neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

urinary bladder neoplasms

,

ovarian epithelial carcinoma

,

neoplasm metastasis

,

liver neoplasms

,

follicular lymphoma

,

,

squamous cell neoplasms

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

uterine cervical neoplasms

,

non-hodgkin lymphoma

,

esophageal neoplasms

,

urologic neoplasms

,

prostatic neoplasms

,

pancreatic ductal carcinoma

,

lymphoid leukemia

,

transitional cell carcinoma

,

esophageal squamous cell carcinoma

,

hodgkin disease

,

cholangiocarcinoma

,

stomach neoplasms

,

castration-resistant prostatic neoplasms

,

kidney neoplasms

,

,

colonic neoplasms

,

kidney diseases

,

uterine neoplasms

,

urethral neoplasms

,

ureteral neoplasms

,

pelvic neoplasms

,

brain neoplasms

,

,

neoplasms by histologic type

,

adenoviridae infections

,

serous cystadenocarcinoma

,

endometrioid carcinoma

,

,

hepatocellular carcinoma

,

,

invasive hydatidiform mole

,

cutaneous malignant melanoma

,

histiocytic sarcoma

,

follicular dendritic cell sarcoma

,

interdigitating dendritic cell sarcoma

,

hemangiosarcoma

,

chronic kidney failure

,

renal insufficiency

,

,

mullerian mixed tumor

,

,

nervous system diseases

,

nerve tissue neoplasms

,

primitive neuroectodermal tumors

,

neuroepithelial neoplasms

,

neuroectodermal tumors

,

bile duct neoplasms

,

,

clear cell adenocarcinoma

,

acinar cell carcinoma

,

,

sezary syndrome

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

,

b-cell chronic lymphocytic leukemia

,

non-muscle invasive bladder neoplasms

,

unknown primary neoplasms

,

immunoblastic lymphadenopathy

,

enteropathy-associated t-cell lymphoma

,

intestinal diseases

,

,

merkel cell carcinoma

,

mouth neoplasms

,

oropharyngeal neoplasms

,

nasopharyngeal neoplasms

,

laryngeal neoplasms

,

hypopharyngeal neoplasms

,

,

malignant fibrous histiocytoma

,

neuroendocrine tumors

,

microsatellite repeats

,

,

multiple myeloma

,

plasma cell neoplasms

,

rectal neoplasms

,

hypersensitivity

,

gastrointestinal stromal tumors

,

biliary tract neoplasms

,

male breast neoplasms

,

adenosquamous carcinoma

,

uveal neoplasms

,

non-small-cell lung carcinoma

,

,

,

,

squamous cell carcinoma of head and neck

,

breast neoplasms

,

head and neck neoplasms

,

squamous cell carcinoma

,

triple negative breast neoplasms

,

,

endometrial neoplasms

,

fallopian tube neoplasms

,

small cell lung carcinoma

,

clostridium infections

,

,

,

,

malignant mesothelioma

,

,

juvenile arthritis

,

,

,

,

,

,

,

rheumatoid arthritis

,

communicable diseases

,

ulcerative colitis

,

,

,

,

papillomavirus infections

,

immunologic deficiency syndromes

,

,

pneumococcal infections

,

prostatic intraepithelial neoplasia

,

carcinoma in situ

,

,

acquired immunodeficiency syndrome

,

uterine cervical dysplasia

,

,

,

coronavirus infections

,

human influenza

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

human papillomavirus recombinant vaccine quadrivalent types 6 11 16 18

,

agammaglobulinemia

,

common variable immunodeficiency

,

papillomaviridae

,

chronic renal insufficiency

,

flavivirus infections

,

,

,

,

,

prediabetic state

,

hypercholesterolemia

,

cerebrovascular disorders

,

diabetes mellitus

,

coronary artery disease

,

peripheral arterial disease

,

,

healthy volunteers/patients

,

myeloid leukemia acute

,

myeloid leukemia

,

bone marrow transplantation

,

Hydroxydaunomycin

,

myeloid leukemia acute

,

myeloid leukemia

,

bone marrow transplantation

,

pancreatic neoplasms

,

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